Mitchell Guttman - Publications, H-index & Citations

Mitchell Guttman

california institute of technology

55H指数

134论文数

5.4W被引数

收录论文 45

发表时间

Genome-wide chromatin recording resolves dynamic cell state changes 全基因组染色质记录解析动态细胞状态变化

Cell Systems

IF7.7

2026-09-02

PREAI

Yodai Takei; Jordan A. Lay; James M. Linton; Duncan M. Chadly; Yoshiki Ochiai; Ron Hadas; Andrew A. Perez; Mario R. Blanco; Paola Laurino; Mitchell Guttman; Michael B. Elowitz

LncRNA-splicing factor condensates regulate hypoxia-responsive pre-mRNA processing near nuclear speckles 长链非编码RNA-剪接因子凝聚体调控缺氧响应的pre-mRNA加工，其位置靠近核斑。

Molecular Cell

IF16.6

2026-03-19

PREAI

You Jin Song; Min Kyung Shinn; Sushant Bangru; Yu Wang; Qinyu Sun; Qinyu Hao; Pankaj Chaturvedi; Susan M. Freier; Pablo Perez-Pinera; Erik R. Nelson; Andrew S. Belmont; Mitchell Guttman; Supriya G. Prasanth; Auinash Kalsotra; Rohit V. Pappu; Kannanganattu V. Prasanth

An integrated view of the structure and function of the human 4D nucleome 人类4D核体结构与功能的综合视图

Nature

IF48.5

2025-12-17

OAAI

Job Dekker; Betul Akgol Oksuz; Yang Zhang; Ye Wang; Miriam K. Minsk; Shuzhen Kuang; Liyan Yang; Johan H. Gibcus; Nils Krietenstein; Oliver J. Rando; Jie Xu; Derek H. Janssens; Steven Henikoff; Alexander Kukalev; Willemin Andréa; Warren Winick-Ng; Rieke Kempfer; Ana Pombo; Miao Yu; Pradeep Kumar; Liguo Zhang; Andrew S. Belmont; Takayo Sasaki; Tom van Schaik; Laura Brueckner; Daan Peric-Hupkes; Bas van Steensel; Ping Wang; Haoxi Chai; Minji Kim; Yijun Ruan; Ran Zhang; Sofia A. Quinodoz; Prashant Bhat; Mitchell Guttman; Wenxin Zhao; Shu Chien; Yuan Liu; Sergey V. Venev; Dariusz Plewczynski; Ibai Irastorza Azcarate; Dominik Szabó; Christoph J. Thieme; Teresa Szczepińska; Mateusz Chiliński; Kaustav Sengupta; Mattia Conte; Andrea Esposito; Alex Abraham; Ruochi Zhang; Yuchuan Wang; Xingzhao Wen; Qiuyang Wu; Yang Yang; Jie Liu; Lorenzo Boninsegna; Asli Yildirim; Yuxiang Zhan; Andrea Maria Chiariello; Simona Bianco; Lindsay Lee; Ming Hu; Yun Li; R. Jordan Barnett; Ashley L. Cook; Daniel J. Emerson; Claire Marchal; Peiyao Zhao; Peter J. Park; Burak H. Alver; Andrew J. Schroeder; Rahi Navelkar; Clara Bakker; William Ronchetti; Shannon Ehmsen; Alexander D. Veit; Nils Gehlenborg; Ting Wang; Daofeng Li; Xiaotao Wang; Mario Nicodemi; Bing Ren; Sheng Zhong; Jennifer E. Phillips-Cremins; David M. Gilbert; Katherine S. Pollard; Frank Alber; Jian Ma; William S. Noble; Feng Yue

SPIDR enables multiplexed mapping of RNA-protein interactions and uncovers a mechanism for selective translational suppression upon cell stress SPIDR实现了RNA-蛋白质相互作用的复用映射，并揭示了一种细胞应激下的选择性翻译抑制机制。

Cell

IF42.5

2025-07-22

OAAI

Erica Wolin; Jimmy K. Guo; Mario R. Blanco; Isabel N. Goronzy; Darvesh Gorhe; Wenzhao Dong; Andrew A. Perez; Abdurrahman Keskin; Elizabeth Valenzuela; Ahmed A. Abdou; Carl R. Urbinati; Ross Kaufhold; H. Tomas Rube; Jailson Brito Querido; Mitchell Guttman; Marko Jovanovic

Inhibition of SARS-CoV-2 growth in the lungs of mice by a peptide-conjugated morpholino oligomer targeting viral RNA

MOLECULAR THERAPY NUCLEIC ACIDS

IF6.1

2024-12-01

OAAI

Sakai, Alexandra; Singh, Gagandeep; Khoshbakht, Mahsa; Bittner, Scott; Lohr, Christiane V.; Diaz-Tapia, Randy; Warang, Prajakta; White, Kris; Le Luo, Luke; Tolbert, Blanton; Blanco, Mario; Chow, Amy; Guttman, Mitchell; Li, Cuiping; Bao, Yiming; Ho, Joses; Maurer-Stroh, Sebastian; Chatterjee, Arnab; Chanda, Sumit; Garcia-Sastre, Adolfo; Schotsaert, Michael; Teijaro, John R.; Moulton, Hong M.; Stein, David A.

ChIP-DIP maps binding of hundreds of proteins to DNA simultaneously and identifies diverse gene regulatory elements

NATURE GENETICS

IF31.8

2024-11-25

PREAI

Perez, Andrew A.; Goronzy, Isabel N.; Blanco, Mario R.; Yeh, Benjamin T.; Guo, Jimmy K.; Lopes, Carolina S.; Ettlin, Olivia; Burr, Alex; Guttman, Mitchell

PRC2-RNA interactions: Viewpoint from Jimmy K. Guo, Mario R. Blanco, and Mitchell Guttman PRC2-RNA相互作用：Jimmy K. Guo、Mario R. Blanco和Mitchell Guttman的观点

MOLECULAR CELL

IF16.6

2024-10-01

PREAI

Guo, Jimmy K.; Blanco, Mario R.; Guttman, Mitchell

Denaturing purifications demonstrate that PRC2 and other widely reported chromatin proteins do not appear to bind directly to RNA in vivo

MOLECULAR CELL

IF16.6

2024-04-01

OAAI

Guo, Jimmy K.; Blanco, Mario R.; Walkup, Ward G.; Bonesteele, Grant; Urbinati, Carl R.; Banerjee, Abhik K.; Chow, Amy; Ettlin, Olivia; Strehle, Mackenzie; Peyda, Parham; Amaya, Enrique; Trinh, Vickie; Guttman, Mitchell

Long non-coding RNAs: definitions, functions, challenges and recommendations 长链非编码rna: 定义、功能、挑战和建议

NATURE REVIEWS MOLECULAR CELL BIOLOGY

IF90.2

2023-01-03

711

OAAI

Mattick, John S. S.; Amaral, Paulo P. P.; Carninci, Piero; Carpenter, Susan; Chang, Howard Y. Y.; Chen, Ling-Ling; Chen, Runsheng; Dean, Caroline; Dinger, Marcel E. E.; Fitzgerald, Katherine A. A.; Gingeras, Thomas R. R.; Guttman, Mitchell; Hirose, Tetsuro; Huarte, Maite; Johnson, Rory; Kanduri, Chandrasekhar; Kapranov, Philipp; Lawrence, Jeanne B. B.; Lee, Jeannie T. T.; Mendell, Joshua T. T.; Mercer, Timothy R. R.; Moore, Kathryn J. J.; Nakagawa, Shinichi; Rinn, John L. L.; Spector, David L. L.; Ulitsky, Igor; Wan, Yue; Wilusz, Jeremy E. E.; Wu, Mian

Simultaneous mapping of 3D structure and nascent RNAs argues against nuclear compartments that preclude transcription

CELL REPORTS

IF6.9

2022-11-01

OAAI

Goronzy, Isabel N.; Quinodoz, Sofia A.; Jachowicz, Joanna W.; Ollikainen, Noah; Bhat, Prashant; Guttman, Mitchell

Regulatory non-coding RNAs: everything is possible, but what is important?

NATURE METHODS

IF32.1

2022-10-06

PREAI

Guo, Jimmy K.; Guttman, Mitchell

Integrative genome modeling platform reveals essentiality of rare contact events in 3D genome organizations

NATURE METHODS

IF32.1

2022-07-11

OAAI

Boninsegna, Lorenzo; Yildirim, Asli; Polles, Guido; Quinodoz, Sofia A.; Finn, Elizabeth; Guttman, Mitchell; Zhou, Xianghong Jasmine; Alber, Frank; Zhan, Yuxiang

Xist spatially amplifies SHARP/SPEN recruitment to balance chromosome-wide silencing and specificity to the X chromosome

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2022-03-17

OAAI

Jachowicz, Joanna W.; Strehle, Mackenzie; Banerjee, Abhik K.; Blanco, Mario R.; Thai, Jasmine; Guttman, Mitchell

SPRITE: a genome-wide method for mapping higher-order 3D interactions in the nucleus using combinatorial split-and-pool barcoding

NATURE PROTOCOLS

IF16

2022-01-10

PREAI

Quinodoz, Sofia A.; Bhat, Prashant; Chovanec, Peter; Jachowicz, Joanna W.; Ollikainen, Noah; Detmar, Elizabeth; Soehalim, Elizabeth; Guttman, Mitchell

Single-cell measurement of higher-order 3D genome organization with scSPRITE

NATURE BIOTECHNOLOGY

IF41.7

2021-08-23

OAAI

Arrastia, Mary, V; Jachowicz, Joanna W.; Ollikainen, Noah; Curtis, Matthew S.; Lai, Charlotte; Quinodoz, Sofia A.; Selck, David A.; Ismagilov, Rustem F.; Guttman, Mitchell

Essential Roles for RNA in Shaping Nuclear Organization

cold spring harbor perspectives in medicine

IF8.4

2021-08-16

PREAI

Quinodoz, Sofia A.; Guttman, Mitchell

Nuclear compartmentalization as a mechanism of quantitative control of gene expression

NATURE REVIEWS MOLECULAR CELL BIOLOGY

IF90.2

2021-08-02

131

PREAI