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M

Mitchell Guttman

California Institute of Technology
H指数:55
被引数:5.4万

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LncRNA-splicing factor condensates regulate hypoxia-responsive pre-mRNA processing near nuclear speckles

长链非编码RNA-剪接因子凝聚体调控缺氧响应的pre-mRNA加工，其位置靠近核斑。

Molecular Cell
IF16.6
2026-03-190
PRE
You Jin Song; Min Kyung Shinn; Sushant Bangru; Yu Wang; Qinyu Sun; Qinyu Hao; Pankaj Chaturvedi; Susan M. Freier; Pablo Perez-Pinera; Erik R. Nelson; Andrew S. Belmont; Mitchell Guttman; Supriya G. Prasanth; Auinash Kalsotra; Rohit V. Pappu; Kannanganattu V. Prasanth
An integrated view of the structure and function of the human 4D nucleome

人类4D核体结构与功能的综合视图

Nature
IF48.5
2025-12-170
OAAI
Job Dekker; Betul Akgol Oksuz; Yang Zhang; Ye Wang; Miriam K. Minsk; Shuzhen Kuang; Liyan Yang; Johan H. Gibcus; Nils Krietenstein; Oliver J. Rando; Jie Xu; Derek H. Janssens; Steven Henikoff; Alexander Kukalev; Willemin Andréa; Warren Winick-Ng; Rieke Kempfer; Ana Pombo; Miao Yu; Pradeep Kumar; Liguo Zhang; Andrew S. Belmont; Takayo Sasaki; Tom van Schaik; Laura Brueckner; Daan Peric-Hupkes; Bas van Steensel; Ping Wang; Haoxi Chai; Minji Kim; Yijun Ruan; Ran Zhang; Sofia A. Quinodoz; Prashant Bhat; Mitchell Guttman; Wenxin Zhao; Shu Chien; Yuan Liu; Sergey V. Venev; Dariusz Plewczynski; Ibai Irastorza Azcarate; Dominik Szabó; Christoph J. Thieme; Teresa Szczepińska; Mateusz Chiliński; Kaustav Sengupta; Mattia Conte; Andrea Esposito; Alex Abraham; Ruochi Zhang; Yuchuan Wang; Xingzhao Wen; Qiuyang Wu; Yang Yang; Jie Liu; Lorenzo Boninsegna; Asli Yildirim; Yuxiang Zhan; Andrea Maria Chiariello; Simona Bianco; Lindsay Lee; Ming Hu; Yun Li; R. Jordan Barnett; Ashley L. Cook; Daniel J. Emerson; Claire Marchal; Peiyao Zhao; Peter J. Park; Burak H. Alver; Andrew J. Schroeder; Rahi Navelkar; Clara Bakker; William Ronchetti; Shannon Ehmsen; Alexander D. Veit; Nils Gehlenborg; Ting Wang; Daofeng Li; Xiaotao Wang; Mario Nicodemi; Bing Ren; Sheng Zhong; Jennifer E. Phillips-Cremins; David M. Gilbert; Katherine S. Pollard; Frank Alber; Jian Ma; William S. Noble; Feng Yue
SPIDR enables multiplexed mapping of RNA-protein interactions and uncovers a mechanism for selective translational suppression upon cell stress

SPIDR实现了RNA-蛋白质相互作用的复用映射，并揭示了一种细胞应激下的选择性翻译抑制机制。

Cell
IF42.5
2025-07-220
OAAI
Erica Wolin; Jimmy K. Guo; Mario R. Blanco; Isabel N. Goronzy; Darvesh Gorhe; Wenzhao Dong; Andrew A. Perez; Abdurrahman Keskin; Elizabeth Valenzuela; Ahmed A. Abdou; Carl R. Urbinati; Ross Kaufhold; H. Tomas Rube; Jailson Brito Querido; Mitchell Guttman; Marko Jovanovic
Inhibition of SARS-CoV-2 growth in the lungs of mice by a peptide-conjugated morpholino oligomer targeting viral RNA
MOLECULAR THERAPY NUCLEIC ACIDS
IF6.1
2024-12-010
OAAI
Sakai, Alexandra; Singh, Gagandeep; Khoshbakht, Mahsa; Bittner, Scott; Lohr, Christiane V.; Diaz-Tapia, Randy; Warang, Prajakta; White, Kris; Le Luo, Luke; Tolbert, Blanton; Blanco, Mario; Chow, Amy; Guttman, Mitchell; Li, Cuiping; Bao, Yiming; Ho, Joses; Maurer-Stroh, Sebastian; Chatterjee, Arnab; Chanda, Sumit; Garcia-Sastre, Adolfo; Schotsaert, Michael; Teijaro, John R.; Moulton, Hong M.; Stein, David A.
Genome organization around nuclear speckles drives mRNA splicing efficiency

围绕核斑点的基因组组织驱动mRNA剪接效率

Nature
IF48.5
2024-05-080
PRE
Prashant Bhat; Amy Chow; Benjamin Emert; Olivia Ettlin; Sofia A. Quinodoz; Mackenzie Strehle; Yodai Takei; Alex Burr; Isabel N. Goronzy; Allen W. Chen; Wesley Huang; Jose Lorenzo M. Ferrer; Elizabeth Soehalim; Say-Tar Goh; Tara Chari; Delaney K. Sullivan; Mario R. Blanco; Mitchell Guttman
Long non-coding RNAs: definitions, functions, challenges and recommendations

长链非编码rna: 定义、功能、挑战和建议

NATURE REVIEWS MOLECULAR CELL BIOLOGY
IF90.2
2023-01-03711
OA
Mattick, John S. S.; Amaral, Paulo P. P.; Carninci, Piero; Carpenter, Susan; Chang, Howard Y. Y.; Chen, Ling-Ling; Chen, Runsheng; Dean, Caroline; Dinger, Marcel E. E.; Fitzgerald, Katherine A. A.; Gingeras, Thomas R. R.; Guttman, Mitchell; Hirose, Tetsuro; Huarte, Maite; Johnson, Rory; Kanduri, Chandrasekhar; Kapranov, Philipp; Lawrence, Jeanne B. B.; Lee, Jeannie T. T.; Mendell, Joshua T. T.; Mercer, Timothy R. R.; Moore, Kathryn J. J.; Nakagawa, Shinichi; Rinn, John L. L.; Spector, David L. L.; Ulitsky, Igor; Wan, Yue; Wilusz, Jeremy E. E.; Wu, Mian

研究方向

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Manuel Garber
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M
Mario R. Blanco
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S
Sofia A. Quinodoz
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A
Aviv Regev
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E
Eric S. Lander
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H 指数:100论文数:291被引数:9.7万
C
Chad Nusbaum
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James Robinson
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A
Andreas Gnirke
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