Sonia Laı́n

Karolinska Institutet

H指数:46

被引数:8,827

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荣誉奖项

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Retinoblastoma vulnerability to combined de novo and salvage pyrimidine ribonucleotide synthesis pharmacologic blockage

HELIYON

IF3.6

2024-01-010

OAAI

Modulation of p53 C-Terminal Acetylation by Mdm2, p14ARF, and Cytoplasmic SirT2 (vol 12, pg 471, 2013)

MOLECULAR CANCER THERAPEUTICS

IF5.5

2023-12-010

Publisher Correction: A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage (vol 14, 5019, 2023)

NATURE COMMUNICATIONS

IF15.7

2023-08-182

OAAI

Ladds, Marcus J. G. W.; van Leeuwen, Ingeborg M. M.; Drummond, Catherine J.; Chu, Su; Healy, Alan R.; Popova, Gergana; Fernandez, Andres Pastor; Mollick, Tanzina; Darekar, Suhas; Sedimbi, Saikiran K.; Nekulova, Marta; Sachweh, Marijke C. C.; Campbell, Johanna; Higgins, Maureen; Tuck, Chloe; Popa, Mihaela; Safont, Mireia Mayoral; Gelebart, Pascal; Fandalyuk, Zinayida; Thompson, Alastair M.; Svensson, Richard; Gustavsson, Anna-Lena; Johansson, Lars; Faernegardh, Katarina; Yngve, Ulrika; Saleh, Aljona; Haraldsson, Martin; D'Hollander, Agathe C. A.; Franco, Marcela; Zhao, Yan; Hakansson, Maria; Walse, Bjoern; Larsson, Karin; Peat, Emma M.; Pelechano, Vicent; Lunec, John; Vojtesek, Borivoj; Carmena, Mar; Earnshaw, William C.; McCarthy, Anna R.; Westwood, Nicholas J.; Arsenian-Henriksson, Marie; Lane, David P.; Bhatia, Ravi; McCormack, Emmet; Lain, Sonia

Multiple C-terminal lysine residues target p53 for ubiquitin-proteasome-mediated degradation

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-28396

OAAI

Proof-of-principle studies on a strategy to enhance nucleotide imbalance specifically in cancer cells (vol 15, pg 548, 2022)

CELL DEATH DISCOVERY

IF7

2022-11-300

OAAI

Proof-of-principle studies on a strategy to enhance nucleotide imbalance specifically in cancer cells

CELL DEATH DISCOVERY

IF7

2022-11-243

OAAI

Asymmetric inheritance of cytoophidia could contribute to determine cell fate and plasticity The onset of alternative differentiation patterns in daughter cells may rely on the acquisition of either CTPS or IMPDH cytoophidia

BIOESSAYS

IF2.7

2022-10-091

OAAI

Exploitation of dihydroorotate dehydrogenase (DHODH) and p53 activation as therapeutic targets: A case study in polypharmacology

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2020-12-0114

OAAI

Modulating pyrimidine ribonucleotide levels for the treatment of cancer

CANCER & METABOLISM

IF5.3

2020-06-0934

OAAI

Optimization of Tetrahydroindazoles as Inhibitors of Human Dihydroorotate Dehydrogenase and Evaluation of Their Activity and In Vitro Metabolic Stability

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2020-03-2616

OAAI

High intracellular stability of the spidroin N-terminal domain in spite of abundant amyloidogenic segments revealed by in-cell hydrogen/deuterium exchange mass spectrometry

FEBS JOURNAL

IF4.2

2019-12-2014

OAAI

Constitutive activation of WASp in X-linked neutropenia renders neutrophils hyperactive

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2018-08-2032

A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage

NATURE COMMUNICATIONS

IF15.7

2018-05-227

OAAI

Ladds, Marcus J. G. W.; van Leeuwen, Ingeborg M. M.; Drummond, Catherine J.; Chu, Su; Healy, Alan R.; Popova, Gergana; Fernandez, Andres Pastor; Mollick, Tanzina; Darekar, Suhas; Sedimbi, Saikiran K.; Nekulova, Marta; Sachweh, Marijke C. C.; Campbell, Johanna; Higgins, Maureen; Tuck, Chloe; Popa, Mihaela; Safont, Mireia Mayoral; Gelebart, Pascal; Fandalyuk, Zinayida; Thompson, Alastair M.; Svensson, Richard; Gustavsson, Anna-Lena; Johansson, Lars; Farnegardh, Katarina; Yngve, Ulrika; Saleh, Aljona; Haraldsson, Martin; D'Hollander, Agathe C. A.; Franco, Marcela; Zhao, Yan; Hakansson, Maria; Walse, Bjorn; Larsson, Karin; Peat, Emma M.; Pelechano, Vicent; Lunec, John; Vojtesek, Borivoj; Carmena, Mar; Earnshaw, William C.; McCarthy, Anna R.; Westwood, Nicholas J.; Arsenian-Henriksson, Marie; Lane, David P.; Bhatia, Ravi; McCormack, Emmet; Lain, Sonia

A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage

NATURE COMMUNICATIONS

IF15.7

2018-03-1679

OAAI

Ladds, Marcus J. G. W.; van Leeuwen, Ingeborg M. M.; Drummond, Catherine J.; Chu, Su; Healy, Alan R.; Popova, Gergana; Fernandez, Andres Pastor; Mollick, Tanzina; Darekar, Suhas; Sedimbi, Saikiran K.; Nekulova, Marta; Sachweh, Marijke C. C.; Campbell, Johanna; Higgins, Maureen; Tuck, Chloe; Popa, Mihaela; Safont, Mireia Mayoral; Gelebart, Pascal; Fandalyuk, Zinayida; Thompson, Alastair M.; Svensson, Richard; Gustavsson, Anna-Lena; Johansson, Lars; Farnegardh, Katarina; Yngve, Ulrika; Saleh, Aljona; Haraldsson, Martin; D'Hollander, Agathe C. A.; Franco, Marcela; Zhao, Yan; Hakansson, Maria; Walse, Bjorn; Larsson, Karin; Peat, Emma M.; Pelechano, Vicent; Lunec, John; Vojtesek, Borivoj; Carmena, Mar; Earnshaw, William C.; McCarthy, Anna R.; Westwood, Nicholas J.; Arsenian-Henriksson, Marie; Lane, David P.; Bhatia, Ravi; McCormack, Emmet; Lain, Sonia

Lipids Shape the Electron Acceptor-Binding Site of the Peripheral Membrane Protein Dihydroorotate Dehydrogenase

CELL CHEMICAL BIOLOGY

IF7.2

2018-03-0125

OAAI

cMyc-p53 feedback mechanism regulates the dynamics of T lymphocytes in the immune response

CELL CYCLE

IF3.4

2016-03-1710

OAAI

Acetylation site specificities of lysine deacetylase inhibitors in human cells

人细胞中赖氨酸脱乙酰酶抑制剂的乙酰化位点特异性