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A

Aviad Tsherniak

broad institute of harvard and massachusetts institute of technology
H指数:55
被引数:2.5万

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Multiplex CRISPR/Cas9-Based Genome Editing in Human Hematopoietic Stem Cells Models Clonal Hematopoiesis and Myeloid Neoplasia (vol 21, pg 547, 2017)

Multiplex CRISPR/Cas9-Based Genome Editing in Human Hematopoietic Stem Cells Models Clonal Hematopoiesis and Myeloid Neoplasia (vol 21, pg 547, 2017)

CELL STEM CELL
IF20.4
2024-10-010
PRE
Tothova, Zuzana; Krill-Burger, John M.; Popova, Katerina D.; Landers, Catherine C.; Sievers, Quinlan L.; Yudovich, David; Belizaire, Roger; Aster, Jon C.; Morgan, Elizabeth A.; Tsherniak, Aviad; Ebert, Benjamin L.
Genome-scale functional genomics identify genes preferentially essential for multiple myeloma cells compared to other neoplasias
NATURE CANCER
IF28.5
2023-05-2615
PRE
Simoes, Ricardo de Matos; Shirasaki, Ryosuke; Downey-Kopyscinski, Sondra L.; Matthews, Geoffrey M.; Barwick, Benjamin G.; Gupta, Vikas A.; Dupere-Richer, Daphne; Yamano, Shizuka; Hu, Yiguo; Sheffer, Michal; Dhimolea, Eugen; Dashevsky, Olga; Gandolfi, Sara; Ishiguro, Kazuya; Meyers, Robin M.; Bryan, Jordan G.; Dharia, Neekesh V.; Hengeveld, Paul J.; Bruggenthies, Johanna B.; Tang, Huihui; Aguirre, Andrew J.; Sievers, Quinlan L.; Ebert, Benjamin L.; Glassner, Brian J.; Ott, Christopher J.; Bradner, James E.; Kwiatkowski, Nicholas P.; Auclair, Daniel; Levy, Joan; Keats, Jonathan J.; Groen, Richard W. J.; Gray, Nathanael S.; Culhane, Aedin C.; McFarland, James M.; Dempster, Joshua M.; Licht, Jonathan D.; Boise, Lawrence H.; Hahn, William C.; Vazquez, Francisca; Tsherniak, Aviad; Mitsiades, Constantine S.
Genome-scale screens identify factors regulating tumor cell responses to natural killer cells

基因组规模筛选确定调节肿瘤细胞对自然杀伤细胞反应的因素

NATURE GENETICS
IF31.8
2021-07-1253
PRE
Sheffer, Michal; Lowry, Emily; Beelen, Nicky; Borah, Minasri; Naffar-Abu Amara, Suha; Mader, Chris C.; Roth, Jennifer A.; Tsherniak, Aviad; Freeman, Samuel S.; Dashevsky, Olga; Gandolfi, Sara; Bender, Samantha; Bryan, Jordan G.; Zhu, Cong; Wang, Li; Tariq, Ifrah; Kamath, Govinda M.; Simoes, Ricardo De Matos; Dhimolea, Eugen; Yu, Channing; Hu, Yiguo; Dufva, Olli; Giannakis, Marios; Syrgkanis, Vasilis; Fraenkel, Ernest; Golub, Todd; Romee, Rizwan; Mustjoki, Satu; Culhane, Aedin C.; Wieten, Lotte; Mitsiades, Constantine S.
Synthetic Lethal Interaction between the ESCRT Paralog Enzymes VPS4A and VPS4B in Cancers Harboring Loss of Chromosome 18q or 16q (vol 33, pg 108493, 2020)
CELL REPORTS
IF6.9
2021-07-011
OAAI
Neggers, Jasper E.; Paolella, Brenton R.; Asfaw, Adhana; Rothberg, Michael V.; Skipper, Thomas A.; Yang, Annan; Kalekar, Radha L.; Krill-Burger, John M.; Dharia, Neekesh V.; Kugener, Guillaume; Kalfon, Jeremie; Yuan, Chen; Dumont, Nancy; Gonzalez, Alfredo; Abdusamad, Mai; Li, Yvonne Y.; Spurr, Liam F.; Wu, Westley W.; Durbin, Adam D.; Wolpin, Brian M.; Piccioni, Federica; Root, David E.; Boehm, Jesse S.; Cherniack, Andrew D.; Tsherniak, Aviad; Hong, Andrew L.; Hahn, William C.; Stegmaier, Kimberly; Golub, Todd R.; Vazquez, Francisca; Aguirre, Andrew J.
A first-generation pediatric cancer dependency map
NATURE GENETICS
IF31.8
2021-03-2295
OAAI
Dharia, Neekesh, V; Kugener, Guillaume; Guenther, Lillian M.; Malone, Clare F.; Durbin, Adam D.; Hong, Andrew L.; Howard, Thomas P.; Bandopadhayay, Pratiti; Wechsler, Caroline S.; Fung, Iris; Warren, Allison C.; Dempster, Joshua M.; Krill-Burger, John M.; Paolella, Brenton R.; Moh, Phoebe; Jha, Nishant; Tang, Andrew; Montgomery, Philip; Boehm, Jesse S.; Hahn, William C.; Roberts, Charles W. M.; McFarland, James M.; Tsherniak, Aviad; Golub, Todd R.; Vazquez, Francisca; Stegmaier, Kimberly
Functional Genomics Identify Distinct and Overlapping Genes Mediating Resistance to Different Classes of Heterobifunctional Degraders of Oncoproteins

功能基因组学鉴定介导对不同类别的癌蛋白异双功能降解物抗性的不同和重叠基因

CELL REPORTS
IF6.9
2021-01-0168
OA
Shirasaki, Ryosuke; Matthews, Geoffrey M.; Gandolfi, Sara; Simoes, Ricardo de Matos; Buckley, Dennis L.; Vora, Joseline Raja; Sievers, Quinlan L.; Bruggenthies, Johanna B.; Dashevsky, Olga; Poarch, Haley; Tang, Huihui; Bariteau, Megan A.; Sheffer, Michal; Hu, Yiguo; Downey-Kopyscinski, Sondra L.; Hengeveld, Paul J.; Glassner, Brian J.; Dhimolea, Eugen; Ott, Christopher J.; Zhang, Tinghu; Kwiatkowski, Nicholas P.; Laubach, Jacob P.; Schlossman, Robert L.; Richardson, Paul G.; Culhane, Aedin C.; Groen, Richard W. J.; Fischer, Eric S.; Vazquez, Francisca; Tsherniak, Aviad; Hahn, William C.; Levy, Joan; Auclair, Daniel; Licht, Jonathan D.; Keats, Jonathan J.; Boise, Lawrence H.; Ebert, Benjamin L.; Bradner, James E.; Gray, Nathanael S.; Mitsiades, Constantine S.
Synthetic Lethal Interaction between the ESCRT Paralog Enzymes VPS4A and VPS4B in Cancers Harboring Loss of Chromosome 18q or 16q
CELL REPORTS
IF6.9
2020-12-0127
OAAI
Neggers, Jasper E.; Paolella, Brenton R.; Asfaw, Adhana; Rothberg, Michael, V; Skipper, Thomas A.; Yang, Annan; Kalekar, Radha L.; Krill-Burger, John M.; Dharia, Neekesh, V; Kugener, Guillaume; Kalfon, Jeremie; Yuan, Chen; Dumont, Nancy; Gonzalez, Alfredo; Abdusamad, Mai; Li, Yvonne Y.; Spurr, Liam F.; Wu, Westley W.; Durbin, Adam D.; Wolpin, Brian M.; Piccioni, Federica; Root, David E.; Boehm, Jesse S.; Cherniack, Andrew D.; Tsherniak, Aviad; Hong, Andrew L.; Hahn, William C.; Stegmaier, Kimberly; Golub, Todd R.; Vazquez, Francisca; Aguirre, Andrew J.
Pan-cancer single-cell RNA-seq identifies recurring programs of cellular heterogeneity
NATURE GENETICS
IF31.8
2020-10-30217
OAAI
Kinker, Gabriela S.; Greenwald, Alissa C.; Tal, Rotem; Orlova, Zhanna; Cuoco, Michael S.; McFarland, James M.; Warren, Allison; Rodman, Christopher; Roth, Jennifer A.; Bender, Samantha A.; Kumar, Bhavna; Rocco, James W.; Fernandes, Pedro A. C. M.; Mader, Christopher C.; Keren-Shaul, Hadas; Plotnikov, Alexander; Barr, Haim; Tsherniak, Aviad; Rozenblatt-Rosen, Orit; Krizhanovsky, Valery; Puram, Sidharth V.; Regev, Aviv; Tirosh, Itay
Multiplexed single-cell transcriptional response profiling to define cancer vulnerabilities and therapeutic mechanism of action

多重单细胞转录反应分析以定义癌症脆弱性和治疗作用机制

NATURE COMMUNICATIONS
IF15.7
2020-08-2797
OAAI
McFarland, James M.; Paolella, Brenton R.; Warren, Allison; Geiger-Schuller, Kathryn; Shibue, Tsukasa; Rothberg, Michael; Kuksenko, Olena; Colgan, William N.; Jones, Andrew; Chambers, Emily; Dionne, Danielle; Bender, Samantha; Wolpin, Brian M.; Ghandi, Mahmoud; Tirosh, Itay; Rozenblatt-Rosen, Orit; Roth, Jennifer A.; Golub, Todd R.; Regev, Aviv; Aguirre, Andrew J.; Vazquez, Francisca; Tsherniak, Aviad
VPS4A is a synthetic lethal target in VPS4B-deficient cancers due to co-deletion with SMAD4
CANCER RESEARCH
IF16.6
2020-08-150
PRE
Neggers, Jasper E.; Paolella, Brenton R.; Asfaw, Adhana; Rothberg, Michael, V; Skipper, Thomas A.; Kalekar, Radha L.; Krill-Burger, John M.; Hong, Andrew L.; Kugener, Guillaume; Kalfon, Jeremie; Yang, Annan; Yuan, Chen; Dumont, Nancy; Gonzalez, Alfredo; Abdusamad, Mai; Li, Yvonne Y.; Spurr, Liam F.; Wu, Westley W.; Piccioni, Federica; Wolpin, Brian M.; Root, David E.; Boehm, Jesse S.; Cherniack, Andrew D.; Tsherniak, Aviad; Golub, Todd R.; Vazquez, Francisca; Aguirre, Andrew J.
Discovering the anticancer potential of non-oncology drugs by systematic viability profiling
NATURE CANCER
IF28.5
2020-01-20469
OAAI
Corsello, Steven M.; Nagari, Rohith T.; Spangler, Ryan D.; Rossen, Jordan; Kocak, Mustafa; Bryan, Jordan G.; Humeidi, Ranad; Peck, David; Wu, Xiaoyun; Tang, Andrew A.; Wang, Vickie M.; Bender, Samantha A.; Lemire, Evan; Narayan, Rajiv; Montgomery, Philip; Ben-David, Uri; Garvie, Colin W.; Chen, Yejia; Rees, Matthew G.; Lyons, Nicholas J.; McFarland, James M.; Wong, Bang T.; Wang, Li; Dumont, Nancy; O'Hearn, Patrick J.; Stefan, Eric; Doench, John G.; Harrington, Caitlin N.; Greulich, Heidi; Meyerson, Matthew; Vazquez, Francisca; Subramanian, Aravind; Roth, Jennifer A.; Bittker, Joshua A.; Boehm, Jesse S.; Mader, Christopher C.; Tsherniak, Aviad; Golub, Todd R.
Agreement between two large pan-cancer CRISPR-Cas9 gene dependency data sets
NATURE COMMUNICATIONS
IF15.7
2019-12-20155
OAAI
Dempster, Joshua M.; Pacini, Clare; Pantel, Sasha; Behan, Fiona M.; Green, Thomas; Krill-Burger, John; Beaver, Charlotte M.; Younger, Scott T.; Zhivich, Victor; Najgebauer, Hanna; Allen, Felicity; Goncalves, Emanuel; Shepherd, Rebecca; Doench, John G.; Yusa, Kosuke; Vazquez, Francisca; Parts, Leopold; Boehm, Jesse S.; Golub, Todd R.; Hahn, William C.; Root, David E.; Garnett, Mathew J.; Tsherniak, Aviad; Iorio, Francesco

研究方向

暂未获取到该数据
F
Francisca Vázquez
H 指数:76论文数:520被引数:3.3万
W
William C. Hahn
H 指数:147论文数:1,091被引数:10.1万
D
David E. Root
H 指数:106论文数:815被引数:6.9万
T
Todd R. Golub
H 指数:176论文数:757被引数:26.7万
J
Jesse S. Boehm
H 指数:59论文数:332被引数:4.2万
B
Barbara A. Weir
H 指数:52论文数:288被引数:4.4万
K
Kimberly Stegmaier
H 指数:64论文数:757被引数:2.2万
J
John M. Krill-Burger
H 指数:25论文数:91被引数:6,116
J
James M. McFarland
H 指数:36论文数:232被引数:1.3万
N
Neekesh V. Dharia
H 指数:36论文数:297被引数:7,650