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Andrew J. Gifford

children's cancer institute
H指数:32
被引数:6,468

个人简介

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教育背景

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工作经历

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荣誉奖项

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Precision-guided therapy in H3K27-altered diffuse midline glioma

H3K27-改变的弥漫性中线胶质瘤中的精准导向疗法

Nature Communications
IF15.7
2026-05-190
OAAI
Campbell J. L. McKay; Chelsea Mayoh; Phoebe Power; Sophie Jessop; Shampavi Sriharan; Jordan Staunton; Sarah Trinder; Nataliya Zhukova; Cristina Mignone; Dinisha Govender; Frank Alvaro; Peter Downie; Jordan R. Hansford; Tim Hassall; Santosh Valvi; Marion K. Mateos; Paulette Barahona; Andrew J. Gifford; Gabor Tax; Maria Tsoli; Emmy M. Dolman; Marie Wong; Mark Cowley; Glenn M. Marshall; Toby N. Trahair; Paul G. Ekert; Michelle Haber; Vanessa Tyrell; Loretta M. S. Lau; Neevika Manoharan; David S. Ziegler; Dong-Anh Khuong-Quang
P-glycoprotein as a chemotherapy resistance mechanism and biomarker of poor response in high-risk neuroblastoma
EJC Paediatric Oncology
IF0
2025-11-010
OA
Atkinson, Caroline; Kamili, Alvin; Tactacan, Carole M.; Jayatilleke, Nisitha; Rosser, Sebastian P. A.; Saletta, Federica; Gana, Christine C.; Graber, Philipp; Wanninayaka, Amanda; Ignacio, Rosa Mistica C.; Kavallaris, Maria; Gifford, Andrew J.; Lock, Richard B.; Norris, Murray D.; Haber, Michelle; Mayoh, Chelsea; Nath, Christa E.; Trahair, Toby N.; Fletcher, Jamie I.
High-throughput 3D engineered paediatric tumour models for precision medicine

高通量3D工程化儿科肿瘤模型用于精准医学

Molecular Systems Biology
IF7.7
2025-10-010
OAAI
MoonSun Jung; Valentina Poltavets; Joanna N Skhinas; Gabor Tax; Alvin Kamili; Jinhan Xie; Sarah Ghamrawi; Philipp Graber; Jie Mao; Marie Wong-Erasmus; Louise Cui; Kathleen Kimpton; Pooja Venkat; Chelsea Mayoh; Angela Lin; Emmy D G Fleuren; Ashleigh M Fordham; Zara Barger; John Grady; David M Thomas; Eric Y Du; Nicole S Graf; Mark J Cowley; Andrew J Gifford; Jamie I Fletcher; Loretta M S Lau; M Emmy M Dolman; J Justin Gooding; Maria Kavallaris
Returning raw genomic data to research participants in a pediatric cancer precision medicine trial (vol 10, 12, 2025)

在儿科癌症精准医学试验（第10卷，第12期，2025年）中向研究参与者返还原始基因组数据

NPJ GENOMIC MEDICINE
IF4.8
2025-03-240
OA
Barlow-Stewart, Kristine; Courtney, Eliza; Cowley, Mark; Ebzery, Camron; Fuentes Bolanos, Noemi; Gifford, Andrew J.; Harden, Hazel; Josephi-Taylor, Sarah; Kotecha, Rishi S.; Mateos, Marion K.; Manzur, Mitali; Milnes, Di; Nielsen, Jane; O'Connor, Matthew; Padhye, Bhavna; Pitman, Catherine; Pitman, Elizabeth; Pinese, Mark; Speechly, Catherine; Sullivan, Ashleigh; Tucker, Katherine; Tyrrell, Vanessa; Warby, Meera; Wood, Andrew; Ziegler, David S.; Johnston, Carolyn
The CD123 antibody-drug conjugate pivekimab sunirine exerts profound activity in preclinical models of pediatric acute lymphoblastic leukemia

CD123抗体药物偶联物pivekimab sunirine在儿童急性淋巴细胞白血病临床前模型中表现出显著的活性。

HEMASPHERE
IF14.6
2025-01-171
OAAI
Watts, Ben; Smith, Christopher M.; Evans, Kathryn; Gifford, Andrew J.; Mohamed, Sara M. A.; Erickson, Stephen W.; Earley, Eric J.; Neuhauser, Steven; Stearns, Timothy M.; Philip, Vivek M.; Chuang, Jeffrey H.; Zweidler-McKay, Patrick A.; Lakshmikanthan, Sribalaji; Jocoy, Emily L.; Bult, Carol J.; Teicher, Beverly A.; Smith, Malcolm A.
The third generation AKR1C3-activated prodrug, ACHM-025, eradicates disease in preclinical models of aggressive T-cell acute lymphoblastic leukemia
BLOOD CANCER JOURNAL
IF11.6
2024-11-060
OAAI
Toscan, Cara E.; McCalmont, Hannah; Ashoorzadeh, Amir; Lin, Xiaojing; Fu, Zhe; Doculara, Louise; Kosasih, Hansen J.; Cadiz, Roxanne; Zhou, Anthony; Williams, Sarah; Evans, Kathryn; Khalili, Faezeh; Cai, Ruilin; Yeats, Kristy L.; Gifford, Andrew J.; Pickford, Russell; Mayoh, Chelsea; Xie, Jinhan; Henderson, Michelle J.; Trahair, Toby N.; Patterson, Adam V.; Smaill, Jeff B.; de Bock, Charles E.; Lock, Richard B.
Golgi-localized Ring Finger Protein 121 is necessary for MYCN-driven neuroblastoma tumorigenesis

高尔基体定位的环指蛋白121是MYCN驱动的神经母细胞瘤肿瘤发生所必需的

COMMUNICATIONS BIOLOGY
IF5.1
2024-10-140
OAAI
Cheung, Belamy B.; Mittra, Ritu; Murray, Jayne; Wang, Qian; Seneviratne, Janith A.; Raipuria, Mukesh; Wong, Iris Poh Ling; Restuccia, David; Gifford, Andrew; Salib, Alice; Sutton, Selina; Huang, Libby; Ferdowsi, Parisa Vahidi; Tsang, Joanna; Sekyere, Eric; Mayoh, Chelsea; Luo, Lin; Brown, Darren L.; Stow, Jennifer L.; Zhu, Shizhen; Young, Richard J.; Solomon, Benjamin J.; Chappaz, Stephane; Kile, Benjamin; Kueh, Andrew; Herold, Marco J.; Hilton, Douglas J.; Liu, Tao; Norris, Murray D.; Haber, Michelle; Carter, Daniel R.; Parker, Michael W.; Marshall, Glenn M.
The transcriptional co-repressor Runx1t1 is essential for MYCN-driven neuroblastoma tumorigenesis

转录共阻遏物Runx1t1对于MYCN驱动的神经母细胞瘤肿瘤发生至关重要

NATURE COMMUNICATIONS
IF15.7
2024-07-111
OAAI
Murray, Jayne E.; Valli, Emanuele; Milazzo, Giorgio; Mayoh, Chelsea; Gifford, Andrew J.; Fletcher, Jamie I.; Xue, Chengyuan; Jayatilleke, Nisitha; Salehzadeh, Firoozeh; Gamble, Laura D.; Rouaen, Jourdin R. C.; Carter, Daniel R.; Forgham, Helen; Sekyere, Eric O.; Keating, Joanna; Eden, Georgina; Allan, Sophie; Alfred, Stephanie; Kusuma, Frances K.; Clark, Ashleigh; Webber, Hannah; Russell, Amanda J.; de Weck, Antoine; Kile, Benjamin T.; Santulli, Martina; De Rosa, Piergiuseppe; Fleuren, Emmy D. G.; Gao, Weiman; Wilkinson-White, Lorna; Low, Jason K. K.; Mackay, Joel P.; Marshall, Glenn M.; Hilton, Douglas J.; Giorgi, Federico M.; Koster, Jan; Perini, Giovanni; Haber, Michelle; Norris, Murray D.
PRECISION GUIDED THERAPY PROVIDES CLINICAL BENEFIT IN H3K27-ALTERED DIFFUSE MIDLINE GLIOMA
NEURO-ONCOLOGY
IF13.4
2024-06-180
OAAI
McKay, Campbell; Power, Phoebe; Staunton, Jordan; Sriharan, Shampavi; Jessop, Sophie; Zhukova, Nataliya; Trinder, Sarah; Govender, Dinisha; Barahona, Paulette; Gifford, Andrew J.; Mignone, Cristina; Xie, Angela; Tax, Gabor; Tsoli, Maria; Dolman, Emmy; Mayoh, Chelsea; Wong, Marie; Cowley, Mark; Marshall, Glenn; Trahair, Toby; Lock, Richard B.; Ekert, Paul; Haber, Michelle; Tyrell, Vanessa; Lau, Loretta; Manoharan, Neevika; Ziegler, David S.; Khuong-Quang, Dong-Anh
Precision-guided treatment in high-risk pediatric cancers
NATURE MEDICINE
IF50
2024-06-067
OAAI
Lau, Loretta M. S.; Khuong-Quang, Dong-Anh; Mayoh, Chelsea; Wong, Marie; Barahona, Paulette; Ajuyah, Pamela; Senapati, Akanksha; Nagabushan, Sumanth; Sherstyuk, Alexandra; Altekoester, Ann-Kristin; Fuentes-Bolanos, Noemi A.; Yeung, Veronica; Sullivan, Ashleigh; Omer, Natacha; Diamond, Yonatan; Jessop, Sophie; Battaglia, Lauren; Zhukova, Nataliya; Cui, Louise; Lin, Angela; Gifford, Andrew J.; Fleuren, Emmy D. G.; Dalla-Pozza, Luciano; Moore, Andrew S.; Khaw, Seong-Lin; Eisenstat, David D.; Gottardo, Nicholas G.; Wood, Paul J.; Tapp, Heather; Alvaro, Frank; McCowage, Geoffrey; Nicholls, Wayne; Hansford, Jordan R.; Manoharan, Neevika; Kotecha, Rishi S.; Mateos, Marion K.; Lock, Richard B.; Tyrrell, Vanessa; Haber, Michelle; Trahair, Toby N.; Cowley, Mark J.; Ekert, Paul G.; Marshall, Glenn M.; Ziegler, David S.
High-Throughput Drug Screening of Primary Tumor Cells Identifies Therapeutic Strategies for Treating Children with High-Risk Cancer

原发性肿瘤细胞的高通量药物筛选确定治疗高危癌症儿童的治疗策略

CANCER RESEARCH
IF16.6
2023-07-3114
OAAI
Mayoh, Chelsea; Mao, Jie; Xie, Jinhan; Tax, Gabor; Chow, Shu-Oi; Cadiz, Roxanne; Pazaky, Karina; Barahona, Paulette; Ajuyah, Pamela; Trebilcock, Peter; Malquori, Angela; Gunther, Kate; Avila, Anica; Yun, Doo Young; Alfred, Stephanie; Gopalakrishnan, Anjana; Kamili, Alvin; Wong, Marie; Cowley, Mark J.; Jessop, Sophie; Lau, Loretta M. S.; Trahair, Toby N.; Ziegler, David S.; Fletcher, Jamie I.; Gifford, Andrew J.; Tsoli, Maria; Marshall, Glenn M.; Haber, Michelle; Tyrrell, Vanessa; Failes, Timothy W.; Arndt, Greg M.; Lock, Richard B.; Ekert, Paul G.; Dolman, M. Emmy M.
Precision Medicine Is Changing the Roles of Healthcare Professionals, Scientists, and Research Staff: Learnings from a Childhood Cancer Precision Medicine Trial
JOURNAL OF PERSONALIZED MEDICINE
IF3
2023-06-237
OA
Daly, Rebecca; Hetherington, Kate; Hazell, Emily; Wadling, Bethany R.; Tyrrell, Vanessa; Tucker, Katherine M.; Marshall, Glenn M.; Ziegler, David S.; Lau, Loretta; Trahair, Toby N.; O'Brien, Tracey A.; Collins, Kiri; Gifford, Andrew J.; Haber, Michelle; Pinese, Mark; Malkin, David; Cowley, Mark J.; Karpelowsky, Jonathan; Drew, Donna; Jacobs, Chris; Wakefield, Claire E.
A novel transcriptional signature identifies T-cell infiltration in high-risk paediatric cancer

一种新的转录特征识别高危儿科癌症中的T细胞浸润

GENOME MEDICINE
IF11.2
2023-04-033
OAAI
Mayoh, Chelsea; Gifford, Andrew J.; Terry, Rachael; Lau, Loretta M. S.; Wong, Marie; Rao, Padmashree; Shai-Hee, Tyler; Saletta, Federica; Khuong-Quang, Dong-Anh; Qin, Vicky; Mateos, Marion K.; Meyran, Deborah; Miller, Katherine E.; Yuksel, Aysen; Mould, Emily V. A.; Bowen-James, Rachel; Govender, Dinisha; Senapati, Akanksha; Zhukova, Nataliya; Omer, Natacha; Dholaria, Hetal; Alvaro, Frank; Tapp, Heather; Diamond, Yonatan; Pozza, Luciano Dalla; Moore, Andrew S.; Nicholls, Wayne; Gottardo, Nicholas G.; McCowage, Geoffrey; Hansford, Jordan R.; Khaw, Seong-Lin; Wood, Paul J.; Catchpoole, Daniel; Cottrell, Catherine E.; Mardis, Elaine R.; Marshall, Glenn M.; Tyrrell, Vanessa; Haber, Michelle; Ziegler, David S.; Vittorio, Orazio; Trapani, Joseph A.; Cowley, Mark J.; Neeson, Paul J.; Ekert, Paul G.
Histone H3-wild type diffuse midline gliomas with H3K27me3 loss are a distinct entity with exclusive EGFR or ACVR1 mutation and differential methylation of homeobox genes

H3K27me3缺失的组蛋白H3-wild型弥漫性中线胶质瘤是一个独特的实体，具有EGFR或ACVR1突变和同源框基因的差异甲基化

SCIENTIFIC REPORTS
IF3.9
2023-03-077
OAAI
Ajuyah, Pamela; Mayoh, Chelsea; Lau, Loretta M. S.; Barahona, Paulette; Wong, Marie; Chambers, Hazel; Valdes-Mora, Fatima; Senapati, Akanksha; Gifford, Andrew J.; D'Arcy, Colleen; Hansford, Jordan R.; Manoharan, Neevika; Nicholls, Wayne; Williams, Molly M.; Wood, Paul J.; Cowley, Mark J.; Tyrrell, Vanessa; Haber, Michelle; Ekert, Paul G.; Ziegler, David S.; Khuong-Quang, Dong-Anh
Inhibition of mitochondrial translocase SLC25A5 and histone deacetylation is an effective combination therapy in neuroblastoma
INTERNATIONAL JOURNAL OF CANCER
IF4.7
2022-11-1710
OA
Seneviratne, Janith A.; Carter, Daniel R.; Mittra, Rituparna; Gifford, Andrew; Kim, Patrick Y.; Luo, Jie-Si; Mayoh, Chelsea; Salib, Alice; Rahmanto, Aldwin S.; Murray, Jayne; Cheng, Ngan C.; Nagy, Zsuzsanna; Wang, Qian; Kleynhans, Ane; Tan, Owen; Sutton, Selina K.; Xue, Chengyuan; Chung, Sylvia A.; Zhang, Yizhuo; Sun, Chengtao; Zhang, Li; Haber, Michelle; Norris, Murray D.; Fletcher, Jamie I.; Liu, Tao; Dilda, Pierre J.; Hogg, Philip J.; Cheung, Belamy B.; Marshall, Glenn M.
In vitro and in vivo drug screens of tumor cells identify novel therapies for high-risk child cancer

肿瘤细胞的体外和体内药物筛选确定高危儿童癌症的新疗法

EMBO MOLECULAR MEDICINE
IF8.3
2021-12-2019
OAAI
Lau, Loretta M. S.; Mayoh, Chelsea; Xie, Jinhan; Barahona, Paulette; MacKenzie, Karen L.; Wong, Marie; Kamili, Alvin; Tsoli, Maria; Failes, Tim W.; Kumar, Amit; Mould, Emily V. A.; Gifford, Andrew; Chow, Shu-Oi; Pinese, Mark; Fletcher, Jamie, I; Arndt, Greg M.; Khuong-Quang, Dong-Anh; Wadham, Carol; Eden, Georgina; Trebilcock, Peter; Joshi, Swapna; Alfred, Stephanie; Gopalakrishnan, Anjana; Khan, Aaminah; Wade, Dylan Grebert; Strong, Patrick A.; Manouvrier, Elodie; Morgan, Lisa T.; Cadiz, Roxanne; Ung, Caitlin; Thomas, David M.; Tucker, Katherine M.; Warby, Meera; McCowage, Geoffrey B.; Dalla-Pozza, Luciano; Byrne, Jennifer A.; Saletta, Federica; Fellowes, Andrew; Fox, Stephen B.; Norris, Murray D.; Tyrrell, Vanessa; Trahair, Toby N.; Lock, Richard B.; Cowley, Mark J.; Ekert, Paul G.; Haber, Michelle; Ziegler, David S.; Marshall, Glenn M.
Neuro-Oncology Advances
NEURO-ONCOLOGY ADVANCES
IF4.1
2021-08-255
OAAI
Robertson, Eden G.; Wakefield, Claire E.; Tsoli, Maria; Kellie, Stewart J.; Alvaro, Frank; Gifford, Andrew J.; Weber, Martin A.; Rodriguez, Michael; Kirby, Maria; Ziegler, David S.

研究方向

暂未获取到该数据
M
Michelle Haber
H 指数:65论文数:666被引数:1.6万
C
Chelsea Mayoh
H 指数:33论文数:324被引数:3,974
T
Toby N. Trahair
H 指数:40论文数:270被引数:5,096
G
Glenn M. Marshall
H 指数:62论文数:528被引数:1.1万
M
Murray D. Norris
H 指数:61论文数:515被引数:1.3万
D
David S. Ziegler
H 指数:45论文数:632被引数:8,531
J
Jamie I. Fletcher
H 指数:34论文数:253被引数:9,511
M
Mark J. Cowley
H 指数:63论文数:409被引数:1.9万
P
Paul G. Ekert
H 指数:55论文数:367被引数:1.4万
L
Loretta M. S. Lau
H 指数:43论文数:201被引数:1.8万