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E

Evan C. Lien

Van Andel Institute
H指数:24
被引数:3,551

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Dietary restriction reprograms CD8+ T cell fate to enhance anti-tumour immunity and immunotherapy responses

饮食限制重新编程CD8 T细胞命运以增强抗肿瘤免疫和免疫治疗反应

Nature Metabolism
IF20.8
2025-12-090
OAAI
Brandon M. Oswald; Lisa M. DeCamp; Joseph Longo; Michael S. Dahabieh; Nicholas Bunda; Benjamin K. Johnson; McLane J. Watson; Shixin Ma; Samuel E. J. Preston; Ryan D. Sheldon; Michael P. Vincent; Abigail E. Ellis; Molly T. Soper-Hopper; Christine Isaguirre; Dahlya Kamarudin; Hui Shen; Kelsey S. Williams; Peter A. Crawford; Susan Kaech; H. Josh Jang; Evan C. Lien; Connie M. Krawczyk; Russell G. Jones
NOTCH3 mediates metabolic reprogramming and ferroptosis resistance in meningiomas

NOTCH3介导脑膜瘤中的代谢重编程和铁死亡抵抗

NEURO-ONCOLOGY
IF13.4
2025-11-010
OAAI
Sadagopan, Nishanth S.; Gomez, Mateo; Tripathi, Shashwat; Billingham, Leah K.; Delay, Susan L.; Cady, Martha A.; Congivaram, Harrshavasan T. S.; Chia, Tzu-yi; Wan, Hanxiao; Wang, Si; Raleigh, David R.; Kaluba, Faith C.; Lien, Evan C.; Heimberger, Amy B.; Lee-Chang, Catalina; Youngblood, Mark W.; Magill, Stephen T.; Miska, Jason
NOTCH3 drives fatty acid oxidation and ferroptosis resistance in aggressive meningiomas

NOTCH3驱动脂肪酸氧化和铁死亡抗性在侵袭性脑膜瘤中

Journal of Neuro-Oncology
IF3.1
2025-09-090
OA
Nishanth S. Sadagopan; Mateo Gomez; Shashwat Tripathi; Leah K. Billingham; Susan L. DeLay; Martha A. Cady; Harrshavasan T. S. Congivaram; Tzu-Yi Chia; Hanxiao Wan; Si Wang; David R. Raleigh; Faith C. Kaluba; Evan C. Lien; Amy B. Heimberger; Catalina Lee-Chang; Mark W. Youngblood; Stephen T. Magill; Jason M. Miska
Lipid availability influences ferroptosis sensitivity in cancer cells by regulating polyunsaturated fatty acid trafficking

脂质可用性通过调控多不饱和脂肪酸转运影响癌细胞的铁死亡敏感性。

CELL CHEMICAL BIOLOGY
IF7.2
2024-10-013
OAAI
Sokol, Kelly H.; Lee, Cameron J.; Rogers, Thomas J.; Waldhart, Althea; Ellis, Abigail E.; Madireddy, Sahithi; Daniels, Samuel R.; House, Rachel (Rae) J.; Ye, Xinyu; Olesnavich, Mary; Johnson, Amy; Furness, Benjamin R.; Sheldon, Ryan D.; Lien, Evan C.
Short-term post-fast refeeding enhances intestinal stemness via polyamines

短期快速再喂养后通过多胺增强肠道的stemness

Nature
IF48.5
2024-08-210
PRE
Shinya Imada; Saleh Khawaled; Heaji Shin; Sven W. Meckelmann; Charles A. Whittaker; Renan Oliveira Corrêa; Chiara Alquati; Yixin Lu; Guodong Tie; Dikshant Pradhan; Gizem Calibasi-Kocal; Luiza Martins Nascentes Melo; Gabriele Allies; Jonas Rösler; Pia Wittenhofer; Jonathan Krystkiewicz; Oliver J. Schmitz; Jatin Roper; Marco Aurelio Ramirez Vinolo; Luigi Ricciardiello; Evan C. Lien; Matthew G. Vander Heiden; Ramesh A. Shivdasani; Chia-Wei Cheng; Alpaslan Tasdogan; Ömer H. Yilmaz
Ketogenic HMG-CoA lyase and its product β-hydroxybutyrate promote pancreatic cancer progression

生酮hmg-coa裂解酶及其产物 β-羟丁酸促进胰腺癌进展

EMBO JOURNAL
IF8.3
2022-03-2132
OA
Gouirand, Victoire; Gicquel, Tristan; Lien, Evan C.; Jaune-Pons, Emilie; Da Costa, Quentin; Finetti, Pascal; Metay, Elodie; Duluc, Camille; Mayers, Jared R.; Audebert, Stephane; Camoin, Luc; Borge, Laurence; Rubis, Marion; Leca, Julie; Nigri, Jeremy; Bertucci, Francois; Dusetti, Nelson; Iovanna, Juan Lucio; Tomasini, Richard; Bidaut, Ghislain; Guillaumond, Fabienne; Vander Heiden, Matthew G.; Vasseur, Sophie
REV1 inhibitor JH-RE-06 enhances tumor cell response to chemotherapy by triggering senescence hallmarks

REV1抑制剂JH-RE-06通过触发衰老标志增强肿瘤细胞对化疗的反应

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2020-11-0934
OAAI
Chatterjee, Nimrat; Whitman, Matthew A.; Harris, Cynthia A.; Min, Sophia M.; Jonas, Oliver; Lien, Evan C.; Luengo, Alba; Vander Heiden, Matthew G.; Hong, Jiyong; Zhou, Pei; Hemann, Michael T.; Walker, Graham C.

研究方向

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Matthew G. Vander Heiden
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H 指数:28论文数:150被引数:3,411
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Abigail E. Ellis
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Yariv Houvras
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Sagar Chhangawala
H 指数:25论文数:74被引数:4,587
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Wolfram Goessling
H 指数:53论文数:236被引数:1.5万
A
Andrew G. Cox
H 指数:31论文数:104被引数:4,099
K
Kristin Brown
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