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A

Alex Toker

Harvard Medical School
H指数:80
被引数:2.7万

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Androgen deprivation-mediated activation of AKT is enhanced in prostate cancer with TMPRSS2:ERG fusion

雄激素剥夺介导的AKT激活在TMPRSS2:ERG融合的前列腺癌中增强

JOURNAL OF CLINICAL INVESTIGATION
IF13.6
2025-12-010
OA
Ma, Fen; Chen, Sen; Cecchi, Luigi; Ersoy-Fazlioglu, Betul; Russo, Joshua W.; Arai, Seiji; Awad, Seifeldin; Calagua, Carla; Xie, Fang; Poluben, Larysa; Voznesensky, Olga; Ku, Anson T.; Karzai, Fatima; Cai, Changmeng; Einstein, David J.; Ye, Huihui; Yuan, Xin; Toker, Alex; Taplin, Mary-Ellen; Sowalsky, Adam G.; Balk, Steven P.
Multiomic profiling of breast cancer cells uncovers stress MAPK-associated sensitivity to AKT degradation

乳腺癌细胞的多组学分析揭示了与AKT降解相关的应激MAPK敏感性

SCIENCE SIGNALING
IF6.6
2024-02-273
OA
Erickson, Emily C.; You, Inchul; Perry, Grace; Dugourd, Aurelien; Donovan, Katherine A.; Crafter, Claire; Johannes, Jeffrey W.; Williamson, Stuart; Moss, Jennifer I.; Ros, Susana; Ziegler, Robert E.; Barry, Simon T.; Fischer, Eric S.; Gray, Nathanael S.; Madsen, Ralitsa R.; Toker, Alex
JAK-STAT Signaling in Inflammatory Breast Cancer Enables Chemotherapy-Resistant Cell States
CANCER RESEARCH
IF16.6
2022-11-2142
OAAI
Stevens, Laura E.; Peluffo, Guillermo; Qiu, Xintao; Temko, Daniel; Fassl, Anne; Li, Zheqi; Trinh, Anne; Seehawer, Marco; Jovanovic, Bojana; Aleckovic, Masa; Wilde, Callahan M.; Geck, Renee C.; Shu, Shaokun; Kingston, Natalie L.; Harper, Nicholas W.; Almendro, Vanessa; Pyke, Alanna L.; Egri, Shawn B.; Papanastasiou, Malvina; Clement, Kendell; Zhou, Ningxuan; Walker, Sarah; Salas, Jacqueline; Park, So Yeon; Frank, David A.; Meissner, Alexander; Jaffe, Jacob D.; Sicinski, Piotr; Toker, Alex; Michor, Franziska; Long, Henry W.; Overmoyer, Beth A.; Polyak, Kornelia
PI3K drives the de novo synthesis of coenzyme A from vitamin B5

PI3K驱动维生素B5从头合成辅酶a

Nature
IF48.5
2022-07-270
OAAI
Christian C. Dibble; Samuel A. Barritt; Grace E. Perry; Evan C. Lien; Renee C. Geck; Sarah E. DuBois-Coyne; David Bartee; Thomas T. Zengeya; Emily B. Cohen; Min Yuan; Benjamin D. Hopkins; Jordan L. Meier; John G. Clohessy; John M. Asara; Lewis C. Cantley; Alex Toker
FGFR-inhibitor-mediated dismissal of SWI/SNF complexes from YAP-dependent enhancers induces adaptive therapeutic resistance
NATURE CELL BIOLOGY
IF19.1
2021-11-0421
OA
Li, Yihao; Qiu, Xintao; Wang, Xiaoqing; Liu, Hui; Geck, Renee C.; Tewari, Alok K.; Xiao, Tengfei; Font-Tello, Alba; Lim, Klothilda; Jones, Kristen L.; Morrow, Murry; Vadhi, Raga; Kao, Pei-Lun; Jaber, Aliya; Yerrum, Smitha; Xie, Yingtian; Chow, Kin-Hoe; Cejas, Paloma; Nguyen, Quang-De; Long, Henry W.; Liu, X. Shirley; Toker, Alex; Brown, Myles

研究方向

暂未获取到该数据
Y
Y. Rebecca Chin
H 指数:23论文数:100被引数:3,037
L
Lewis C. Cantley
H 指数:214论文数:1,444被引数:20.7万
P
Peter Störz
H 指数:53论文数:192被引数:1.3万
J
John M. Asara
H 指数:115论文数:839被引数:6.1万
W
Wenyi Wei
H 指数:89论文数:440被引数:2.7万
H
Heike Döppler
H 指数:33论文数:111被引数:3,927
E
Evan C. Lien
H 指数:24论文数:68被引数:3,551
R
Renee C. Geck
H 指数:12论文数:77被引数:760
A
Alexandra C. Newton
H 指数:77论文数:337被引数:2.5万
M
Merav Yoeli-Lerner
H 指数:7论文数:14被引数:985