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Alex Toker

harvard medical school

80H指数
420论文数
2.7W被引数
收录论文 114
发表时间
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Scope evolution at the journal of biological chemistry: Advancing molecular insight in a changing scientific landscape《生物化学杂志》的范畴演变：在不断变化的科学格局中推进分子洞察
errJournal of Biological Chemistry
IF3.9
err2026-04-24
err0
errOAAI
errHenrik G. Dohlman; Alex Toker
err分享
err收藏
Androgen deprivation-mediated activation of AKT is enhanced in prostate cancer with TMPRSS2:ERG fusion雄激素剥夺介导的AKT激活在TMPRSS2:ERG融合的前列腺癌中增强
errJOURNAL OF CLINICAL INVESTIGATION
IF13.6
err2025-12-01
err0
errOAAI
errMa, Fen; Chen, Sen; Cecchi, Luigi; Ersoy-Fazlioglu, Betul; Russo, Joshua W.; Arai, Seiji; Awad, Seifeldin; Calagua, Carla; Xie, Fang; Poluben, Larysa; Voznesensky, Olga; Ku, Anson T.; Karzai, Fatima; Cai, Changmeng; Einstein, David J.; Ye, Huihui; Yuan, Xin; Toker, Alex; Taplin, Mary-Ellen; Sowalsky, Adam G.; Balk, Steven P.
err分享
err收藏
The glycosyltransferase ALG3 is an AKT substrate that regulates protein N-glycosylation糖基转移酶ALG3是AKT底物，调节蛋白质N-糖基化。
errJournal of Biological Chemistry
IF3.9
err2025-08-09
err0
errOAAI
errAdrija J. Navarro-Traxler; Laura Ghisolfi; Evan C. Lien; Alex Toker
err分享
err收藏
Parallel phosphoproteomics and metabolomics map the global metabolic tyrosine phosphoproteome平行磷酸化蛋白质组学和代谢组学绘制全球代谢酪氨酸磷酸化蛋白质组图
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2024-11-13
err1
errOAAI
errHillis, Alissandra L.; Tamir, Tigist; Perry, Grace E.; Asara, John M.; Johnson, Jared L.; Yaron, Tomer M.; Cantley, Lewis C.; White, Forest M.; Toker, Alex
err分享
err收藏
Targeting Cholesterol Biosynthesis with Statins Synergizes with AKT Inhibitors in Triple-Negative Breast Cancer
errCANCER RESEARCH
IF16.6
err2024-07-18
err1
errOAAI
errHillis, Alissandra L.; Martin, Timothy D.; Manchester, Haley E.; Hogstrom, Jenny; Zhang, Na; Lecky, Emmalyn; Kozlova, Nina; Lee, Jonah; Persky, Nicole S.; Root, David E.; Brown, Myles; Cichowski, Karen; Elledge, Stephen J.; Muranen, Taru; Fruman, David A.; Barry, Simon T.; Clohessy, John G.; Madsen, Ralitsa R.; Toker, Alex
err分享
err收藏
Identifying Collateral Vulnerabilities in the AKT pathway for Therapeutic Benefit
errCANCER RESEARCH
IF16.6
err2024-05-02
err0
PREAI
errToker, A.
err分享
err收藏
Multiomic profiling of breast cancer cells uncovers stress MAPK-associated sensitivity to AKT degradation乳腺癌细胞的多组学分析揭示了与AKT降解相关的应激MAPK敏感性
errSCIENCE SIGNALING
IF6.6
err2024-02-27
err3
errOAAI
errErickson, Emily C.; You, Inchul; Perry, Grace; Dugourd, Aurelien; Donovan, Katherine A.; Crafter, Claire; Johannes, Jeffrey W.; Williamson, Stuart; Moss, Jennifer I.; Ros, Susana; Ziegler, Robert E.; Barry, Simon T.; Fischer, Eric S.; Gray, Nathanael S.; Madsen, Ralitsa R.; Toker, Alex
err分享
err收藏
PI3K signaling through a biochemical systems lens
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2023-10-01
err9
errOAAI
errMadsen, Ralitsa R.; Toker, Alex
err分享
err收藏
Generative artificial intelligence in Journal of Biological Chemistry
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2023-08-01
err0
errOAAI
errColbran, Roger J.; Toker, Alex
err分享
err收藏
Protein kinase Cδ selectively regulates protein kinase D-dependent activation of NF-κB in oxidative stress signaling
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err233
errOAAI
errStorz, P; Döppler, H; Toker, A
err分享
err收藏
Protein kinase D mediates mitochondrion-to-nucleus signaling and detoxification from mitochondrial reactive oxygen species
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err226
errOAAI
errStorz, P; Döppler, H; Toker, A
err分享
err收藏
FOXO3a Promotes Tumor Cell Invasion through the Induction of Matrix Metalloproteinases
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-21
err139
errOAAI
errStorz, Peter; Doeppler, Heike; Copland, John A.; Simpson, Kaylene J.; Toker, Alex
err分享
err收藏
JAK-STAT Signaling in Inflammatory Breast Cancer Enables Chemotherapy-Resistant Cell States
errCANCER RESEARCH
IF16.6
err2022-11-21
err42
errOAAI
errStevens, Laura E.; Peluffo, Guillermo; Qiu, Xintao; Temko, Daniel; Fassl, Anne; Li, Zheqi; Trinh, Anne; Seehawer, Marco; Jovanovic, Bojana; Aleckovic, Masa; Wilde, Callahan M.; Geck, Renee C.; Shu, Shaokun; Kingston, Natalie L.; Harper, Nicholas W.; Almendro, Vanessa; Pyke, Alanna L.; Egri, Shawn B.; Papanastasiou, Malvina; Clement, Kendell; Zhou, Ningxuan; Walker, Sarah; Salas, Jacqueline; Park, So Yeon; Frank, David A.; Meissner, Alexander; Jaffe, Jacob D.; Sicinski, Piotr; Toker, Alex; Michor, Franziska; Long, Henry W.; Overmoyer, Beth A.; Polyak, Kornelia
err分享
err收藏
2022 Herbert Tabor Early Career Investigator Awards: Call for nominations
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2022-10-01
err0
errOAAI
errFarabaugh, Kenneth T.; Toker, Alex; DeMartino, George
err分享
err收藏
PI 3-Kinase signaling: A journey in three AKTs
errFASEB JOURNAL
IF4.2
err2022-05-13
err0
PREAI
errToker, Alex
err分享
err收藏
FGFR inhibitor mediated dismissal of SWI/SNF complexes from YAP-dependent enhancers induces therapeutic resistance in triple negative breast cancer
errCANCER RESEARCH
IF16.6
err2022-02-15
err0
PREAI
errLi, Yihao; Qiu, Xintao; Wang, Xiaoqing; Liu, Hui; Geck, Renee Geck; Tewari, Alok; Chow, Kin-Hoe; Xiao, Tengfei; Cejas, Paloma; Nguyen, Quang-De; Long, Henry; Liu, Shirley X.; Toker, Alex; Brown, Myles
err分享
err收藏
Can Improved Use of Biomarkers Alter the Fate of PI3K Pathway Inhibitors in the Clinic?改善生物标志物的使用能否改变PI3K通路抑制剂在临床上的命运？
errCANCER RESEARCH
IF16.6
err2021-12-15
err2
errOAAI
errErickson, Emily C.; Toker, Alex
err分享
err收藏
Positive correlation between transcriptomic stemness and PI3K/AKT/mTOR signaling scores in breast cancer, and a counterintuitive relationship with PIK3CA genotype乳腺癌中转录组干性与PI3K/AKT/mTOR信号传导评分之间呈正相关，与PIK3CA基因型之间存在违反直觉的关系
errPLOS GENETICS
IF3.7
err2021-11-11
err19
errOAAI
errMadsen, Ralitsa; Erickson, Emily; Rueda, Oscar; Robin, Xavier K.; Caldas, Carlos; Toker, Alex; Semple, Robert; Vanhaesebroeck, Bart
err分享
err收藏
FGFR-inhibitor-mediated dismissal of SWI/SNF complexes from YAP-dependent enhancers induces adaptive therapeutic resistance
errNATURE CELL BIOLOGY
IF19.1
err2021-11-04
err21
errOAAI
errLi, Yihao; Qiu, Xintao; Wang, Xiaoqing; Liu, Hui; Geck, Renee C.; Tewari, Alok K.; Xiao, Tengfei; Font-Tello, Alba; Lim, Klothilda; Jones, Kristen L.; Morrow, Murry; Vadhi, Raga; Kao, Pei-Lun; Jaber, Aliya; Yerrum, Smitha; Xie, Yingtian; Chow, Kin-Hoe; Cejas, Paloma; Nguyen, Quang-De; Long, Henry W.; Liu, X. Shirley; Toker, Alex; Brown, Myles
err分享
err收藏
The INPP4B Tumor Suppressor Modulates EGFR Trafficking and Promotes Triple-Negative Breast Cancer
errCANCER DISCOVERY
IF33.3
err2020-08-03
err37
errOAAI
errLiu, Hui; Paddock, Marcia N.; Wang, Haibin; Murphy, Charles J.; Geck, Renee C.; Navarro, Adrija J.; Wulf, Gerburg M.; Elemento, Olivier; Haucke, Volker; Cantley, Lewis C.; Toker, Alex
err分享
err收藏

研究方向

暂无研究方向
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