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Stephan Krähenbühl

university of basel

H指数:36

被引数:4,150

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Effect of protein binding on the pharmacokinetics of the six substrates in the Basel phenotyping cocktail in healthy subjects and patients with liver cirrhosis

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

IF4.7

2024-11-010

OA

Allosteric targeting resolves limitations of earlier LFA-1 directed modalities

BIOCHEMICAL PHARMACOLOGY

IF5.6

2023-05-012

PRE

Dose Adjustment in Patients with Liver Cirrhosis - Comparison of Two Different Modeling Approaches

CLINICAL PHARMACOLOGY & THERAPEUTICS

IF5.5

2023-04-207

OAAI

Exploration and application of a liver-on-a-chip device in combination with modelling and simulation for quantitative drug metabolism studies

IF5.4

2022-01-0135

OA

Metamizole is a Moderate Cytochrome P450 Inducer Via the Constitutive Androstane Receptor and a Weak Inhibitor of CYP1A2

CLINICAL PHARMACOLOGY & THERAPEUTICS

IF5.5

2021-01-1916

OAAI

In Vitro to In Vivo Extrapolation of Metabolic Clearance for UGT Substrates Using Short-Term Suspension and Long-Term Co-cultured Human Hepatocytes (vol 22, 131, 2020)

IF3.7

2020-11-061

OAAI

Antiseizure drugs and risk of developing smoking-related chronic obstructive pulmonary disease or lung cancer: A population-based case-control study

抗癫痫药物与吸烟相关的慢性阻塞性肺疾病或肺癌的风险: 一项基于人群的病例对照研究

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

IF3

2020-08-301

OAAI

Anti-αLβ2 antibodies reveal novel endocytotic cross-modulatory functionality

BRITISH JOURNAL OF PHARMACOLOGY

IF7.7

2020-03-093

OAAI

Pharmacokinetics and phenotyping properties of the Basel phenotyping cocktail combination capsule in healthy male adults

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

IF3

2019-12-1216

OAAI

Metamizole-associated neutropenia: Comparison of patients with neutropenia and metamizole-tolerant patients

EUROPEAN JOURNAL OF INTERNAL MEDICINE

IF6.1

2019-10-0110

PREAI

Microdosed midazolam for the determination of cytochrome P450 3A activity: Development and clinical evaluation of a buccal film

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

IF4.7

2019-07-015

PREAI

Cytochrome P450 enzymes contribute to the metabolism of LSD to nor-LSD and 2-oxo-3-hydroxy-LSD: Implications for clinical LSD use

BIOCHEMICAL PHARMACOLOGY

IF5.6

2019-06-0125

PREAI

PGC-1 modulates statin-associated myotoxicity in mice

ARCHIVES OF TOXICOLOGY

IF6.9

2018-12-0313

PREAI

N-demethylation of N-methyl-4-aminoantipyrine, the main metabolite of metamizole

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

IF4.7

2018-07-0112

OAAI

Prediction of Safety Margin and Optimization of Dosing Protocol for a Novel Antibiotic using Quantitative Systems Pharmacology Modeling

CTS-CLINICAL AND TRANSLATIONAL SCIENCE

IF2.8

2018-06-079

OA

An alternative sterility assessment for parenteral drug products using isothermal microcalorimetry

JOURNAL OF APPLIED MICROBIOLOGY

IF3.2

2017-08-0411

PREAI

Mechanisms of hepatotoxicity associated with the monocyclic β-lactam antibiotic BAL30072

ARCHIVES OF TOXICOLOGY

IF6.9

2017-05-2329

PREAI

Downstream effect profiles discern different mechanisms of integrin αLβ2 inhibition

BIOCHEMICAL PHARMACOLOGY

IF5.6

2016-11-015

PREAI

IGF-1 prevents simvastatin-induced myotoxicity in C2C12 myotubes

ARCHIVES OF TOXICOLOGY

IF6.9

2016-10-1221

PREAI

Reduction of hyperbilirubinemia with hypericum extract (St. John's Wort) in a patient with Crigler-Najjar syndrome type II

金丝桃提取物 (圣约翰草) 减少II型crigler-najjar综合征患者的高胆红素血症

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

IF3

2016-03-074

OAAI