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KRASG12C-inhibitor-based combination therapies for pancreatic cancer: insights from drug screening 胰腺癌的KRASG12C-inhibitor-based联合治疗: 来自药物筛选的见解 Contreras, Constanza Tapia; Falke, Jonas Dominik; Seifert, Dana-Magdalena; Schneider, Carolin; Krauss, Lukas; Fang, Xin; Mueller, Denise; Demirdizen, Engin; Spitzner, Melanie; De Oliveira, Tiago; Schneeweis, Christian; Gaedcke, Jochen; Kaulfuss, Silke; Mirzakhani, Kimia; Wollnik, Bernd; Conrads, Karly; Beissbarth, Tim; Salinas, Gabriela; Huegel, Jonas; Beyer, Nils; Rheinlander, Sophia; Sax, Ulrich; Wirth, Matthias; Conradi, Lena-Christin; Reichert, Maximilian; Ellenrieder, Volker; Strobel, Philipp; Ghadimi, Michael; Grade, Marian; Saur, Dieter; Hessmann, Elisabeth; Schneider, Gunter 分享 收藏
A Novel AMPK Inhibitor Sensitizes Pancreatic Cancer Cells to Ferroptosis Induction 一种新的AMPK抑制剂使胰腺癌细胞对铁死亡诱导敏感 Schneider, Carolin; Hilbert, Jorina; Genevaux, Franziska; Hoefer, Stefanie; Krauss, Lukas; Schicktanz, Felix; Contreras, Constanza Tapia; Jansari, Shaishavi; Papargyriou, Aristeidis; Richter, Thorsten; Alfayomy, Abdallah M.; Falcomata, Chiara; Schneeweis, Christian; Orben, Felix; Oellinger, Ruppert; Wegwitz, Florian; Boshnakovska, Angela; Rehling, Peter; Mueller, Denise; Stroebel, Philipp; Ellenrieder, Volker; Conradi, Lena; Hessmann, Elisabeth; Ghadimi, Michael; Grade, Marian; Wirth, Matthias; Steiger, Katja; Rad, Roland; Kuster, Bernhard; Sippl, Wolfgang; Reichert, Maximilian; Saur, Dieter; Schneider, Guenter 分享 收藏
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Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma (vol 21, pg 1163, 2015) BET家族蛋白和组蛋白去乙酰化酶的联合抑制作为胰腺导管腺癌的潜在的基于表观遗传学的疗法 (第21卷，1163页，2015) Mazur, Pawel K.; Herner, Alexander; Mello, Stephano S.; Wirth, Matthias; Hausmann, Simone; Sanchez-Rivera, Francisco J.; Lofgren, Shane M.; Kuschma, Timo; Hahn, Stephan A.; Vangala, Deepak; Trajkovic-Arsic, Marija; Gupta, Aayush; Heid, Irina; Noeel, Peter B.; Braren, Rickmer; Erkan, Mert; Kleeff, Joerg; Sipos, Bence; Sayles, Leanne C.; Heikenwalder, Mathias; Hessmann, Elisabeth; Ellenrieder, Volker; Esposito, Irene; Jacks, Tyler; Bradner, James E.; Khatri, Purvesh; Sweet-Cordero, E. Alejandro; Attardi, Laura D.; Schmid, Roland M.; Schneider, Guenter; Sage, Julien; Siveke, Jens T. 分享 收藏
Characterization of nucleolar SUMO isopeptidases unveils a general p53-independent checkpoint of impaired ribosome biogenesis Doenig, Judith; Mende, Hannah; Gallesio, Jimena Davila; Wagner, Kristina; Hotz, Paul; Schunck, Kathrin; Piller, Tanja; Hoelper, Soraya; Uhan, Sara; Kaulich, Manuel; Wirth, Matthias; Keller, Ulrich; Tascher, Georg; Bohnsack, Katherine E.; Mueller, Stefan 分享 收藏
Actionable loss of SLF2 drives B-cell lymphomagenesis and impairs the DNA damage response Zhang, Le; Wirth, Matthias; Patra, Upayan; Stroh, Jacob; Isaakidis, Konstandina; Rieger, Leonie; Kossatz, Susanne; Milanovic, Maja; Zang, Chuanbing; Demel, Uta; Keiten-Schmitz, Jan; Wagner, Kristina; Steiger, Katja; Rad, Roland; Bassermann, Florian; Mueller, Stefan; Keller, Ulrich; Schick, Markus 分享 收藏
SUMOylation inhibition overcomes proteasome inhibitor resistance in multiple myeloma Heynen, Guus J. J. E.; Baumgartner, Francis; Heider, Michael; Patra, Upayan; Holz, Maximilian; Braune, Jan; Kaiser, Melanie; Schaeffer, Isabell; Bamopoulos, Stefanos A.; Ramberger, Evelyn; Murgai, Arunima; Ng, Yuen Lam Dora; Demel, Uta Margareta; Laue, Dominik; Liebig, Sven; Krueger, Josefine; Janz, Martin; Nogai, Axel; Schick, Markus; Mertins, Philipp; Mueller, Stefan; Bassermann, Florian; Kroenke, Jan; Keller, Ulrich; Wirth, Matthias 分享 收藏
AP1/Fra1 confers resistance to MAPK cascade inhibition in pancreatic cancer Schneeweis, Christian; Diersch, Sandra; Hassan, Zonera; Krauss, Lukas; Schneider, Carolin; Lucarelli, Daniele; Falcomata, Chiara; Steiger, Katja; Oellinger, Rupert; Kraemer, Oliver H.; Arlt, Alexander; Grade, Marian; Schmidt-Supprian, Marc; Hessmann, Elisabeth; Wirth, Matthias; Rad, Roland; Reichert, Maximilian; Saur, Dieter; Schneider, Guenter 分享 收藏
Small-molecule SUMO inhibition for biomarker-informed B-cell lymphoma therapy Demel, Uta M.; Wirth, Matthias; Yousefian, Schayan; Zhang, Le; Isaakidis, Konstandina; Doenig, Judith; Boger, Marlitt; Singh, Nikita; Koese, Hazal; Haas, Simon; Mueller, Stefan; Schick, Markus; Keller, Ulrich 分享 收藏
The OTUD6B-LIN28B-MYC axis determines the proliferative state in multiple myeloma Paulmann, Carmen; Spallek, Ria; Karpiuk, Oleksandra; Heider, Michael; Schaeffer, Isabell; Zecha, Jana; Klaeger, Susan; Walzik, Michaela; Oellinger, Rupert; Engleitner, Thomas; Wirth, Matthias; Keller, Ulrich; Kroenke, Jan; Rudelius, Martina; Kossatz, Susanne; Rad, Roland; Kuster, Bernhard; Bassermann, Florian 分享 收藏
Epigenetic drug screening defines a PRMT5 inhibitor-sensitive pancreatic cancer subtype Orben, Felix; Lankes, Katharina; Schneeweis, Christian; Hassan, Zonera; Jakubowsky, Hannah; Krauss, Lukas; Boniolo, Fabio; Schneider, Carolin; Schaefer, Arlett; Murr, Janine; Schlag, Christoph; Kong, Bo; Oellinger, Rupert; Wang, Chengdong; Beyer, Georg; Mahajan, Ujjwal M.; Xue, Yonggan; Mayerle, Julia; Schmid, Roland M.; Kuster, Bernhard; Rad, Roland; Braun, Christian J.; Wirth, Matthias; Reichert, Maximilian; Saur, Dieter; Schneider, Guenter 分享 收藏
Activated SUMOylation restricts MHC class I antigen presentation to confer immune evasion in cancer Demel, Uta M.; Boeger, Marlitt; Yousefian, Schayan; Grunert, Corinna; Zhang, Le; Hotz, Paul W.; Gottschlich, Adrian; Koese, Hazal; Isaakidis, Konstandina; Vonficht, Dominik; Gruenschlaeger, Florian; Rohleder, Elena; Wagner, Kristina; Doenig, Judith; Igl, Veronika; Brzezicha, Bernadette; Baumgartner, Francis; Habringer, Stefan; Loeber, Jens; Chapuy, Bjoern; Weidinger, Carl; Kobold, Sebastian; Haas, Simon; Busse, Antonia B.; Mueller, Stefan; Wirth, Matthias; Schick, Markus; Keller, Ulrich 分享 收藏
Indirect targeting of MYC sensitizes pancreatic cancer cells to mechanistic target of rapamycin (mTOR) inhibition Schneeweis, Christian; Hassan, Zonera; Ascherl, Katja; Wirth, Matthias; Koutsouli, Stella; Orben, Felix; Krauss, Lukas; Schneider, Carolin; Oellinger, Rupert; Kraemer, Oliver H.; Rad, Roland; Reichert, Maximilian; Robles, Maria S.; Saur, Dieter; Schneider, Gunter 分享 收藏
NOXA expression drives synthetic lethality to RUNX1 inhibition in pancreatic cancer Doffo, Josefina; Bamopoulos, Stefanos A.; Koese, Hazal; Orben, Felix; Zang, Chuanbing; Pons, Miriam; den Dekker, Alexander T.; Brouwer, Rutger W. W.; Baluapuri, Apoorva; Habringer, Stefan; Reichert, Maximillian; Illendula, Anuradha; Kraemer, Oliver H.; Schick, Markus; Wolf, Elmar; van IJcken, Wilfred F. J.; Esposito, Irene; Keller, Ulrich; Schneider, Guenter; Wirth, Matthias 分享 收藏
Genetic alterations of the SUMO isopeptidase SENP6 drive lymphomagenesis and genetic instability in diffuse large B-cell lymphoma Schick, Markus; Zhang, Le; Maurer, Sabine; Maurer, Hans Carlo; Isaakaidis, Konstandina; Schneider, Lara; Patra, Upayan; Schunck, Kathrin; Rohleder, Elena; Hofstetter, Julia; Baluapuri, Apoorva; Scherger, Anna Katharina; Slotta-Huspenina, Julia; Hettler, Franziska; Weber, Julia; Engleitner, Thomas; Maresch, Roman; Slawska, Jolanta; Lewis, Richard; Istvanffy, Rouzanna; Habringer, Stefan; Steiger, Katja; Baiker, Armin; Oostendorp, Robert A. J.; Miething, Cornelius; Lenhof, Hans-Peter; Bassermann, Florian; Chapuy, Bjoern; Wirth, Matthias; Wolf, Elmar; Rad, Roland; Mueller, Stefan; Keller, Ulrich 分享 收藏
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