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Polyamine depletion limits progression of acute leukaemia Gao, Weiman; Karsa, Mawar; Xiao, Lin; Spurling, Dayna; Karsa, Ayu; Ronca, Emma; Bongers, Angelika; Guo, Xinyi; Mayoh, Chelsea; Azfar, Mujahid; Verhelst, Steven H. L.; Tanaka, Katsunori; Cheung, Laurence C.; Kotecha, Rishi S.; Lock, Richard B.; Burns, Mark R.; Vangheluwe, Peter; Norris, Murray D.; Haber, Michelle; Somers, Klaartje 分享 收藏
The polyamine transporter ATP13A3 mediates difluoromethylornithine-induced polyamine uptake in neuroblastoma Azfar, Mujahid; Gao, Weiman; van den Haute, Chris; Xiao, Lin; Karsa, Mawar; Pandher, Ruby; Karsa, Ayu; Spurling, Dayna; Ronca, Emma; Bongers, Angelika; Guo, Xinyi; Mayoh, Chelsea; Fayt, Youri; Schoofs, Arthur; Burns, Mark R.; Verhelst, Steven H. L.; Norris, Murray D.; Haber, Michelle; Vangheluwe, Peter; Somers, Klaartje 分享 收藏
Prediction of tumor origin in cancers of unknown primary origin with cytology-based deep learning 基于细胞学的深度学习预测不明原发癌的肿瘤起源 Tian, Fei; Liu, Dong; Wei, Na; Fu, Qianqian; Sun, Lin; Liu, Wei; Sui, Xiaolong; Tian, Kathryn; Nemeth, Genevieve; Feng, Jingyu; Xu, Jingjing; Xiao, Lin; Han, Junya; Fu, Jingjie; Shi, Yinhua; Yang, Yichen; Liu, Jia; Hu, Chunhong; Feng, Bin; Sun, Yan; Wang, Yunjun; Yu, Guohua; Kong, Dalu; Wang, Meiyun; Li, Wencai; Chen, Kexin; Li, Xiangchun 分享 收藏
Addition of AMXT1501 (polyamine uptake inhibitor) plus DFMO (polyamine synthesis inhibitor) to standard-of-care chemotherapy/anti-GD2 antibody in the TH-MYCN mouse neuroblastoma model, enhances efficacy compared to addition of DFMO alone Murray, Jayne; Pandher, Ruby; Xiao, Lin; Somers, Klaartje; Brand, Jennifer; Mosmann, Erin; Alfred, Stephanie; Kusuma, Frances; Keams, Adam; Park, Julie R.; Marshall, Lynley V.; Gorrini, Chiara; Chesler, Louis; Hogarty, Michael D.; Pearson, Andrew D. J.; Burns, Mark; Fletcher, Jamie I.; Ziegler, David; Norris, Murray D.; Haber, Michelle 分享 收藏
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Molecular Architecture of Quartet MOZ/MORF Histone Acetyltransferase Complexes Ullah, Mukta; Pelletier, Nadine; Xiao, Lin; Zhao, Song Ping; Wang, Kainan; Degerny, Cindy; Tahmasebi, Soroush; Cayrou, Christelle; Doyon, Yannick; Goh, Siew-Lee; Champagne, Nathalie; Cote, Jacques; Yang, Xiang-Jiao 分享 收藏
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The Combination of Curaxin CBL0137 and Histone Deacetylase Inhibitor Panobinostat Delays KMT2A-Rearranged Leukemia Progression Curaxin CBL0137和组蛋白去乙酰化酶抑制剂Panobinostat的组合延缓了KMT2A-Rearranged白血病的进展 Xiao, Lin; Karsa, Mawar; Ronca, Emma; Bongers, Angelika; Kosciolek, Angelika; El-Ayoubi, Ali; Revalde, Jezrael L.; Seneviratne, Janith A.; Cheung, Belamy B.; Cheung, Laurence C.; Kotecha, Rishi S.; Newbold, Andrea; Bjelosevic, Stefan; Arndt, Greg M.; Lock, Richard B.; Johnstone, Ricky W.; Gudkov, Andrei V.; Gurova, Katerina V.; Haber, Michelle; Norris, Murray D.; Henderson, Michelle J.; Somers, Klaartje 分享 收藏
Systematic In Vitro Evaluation of a Library of Approved and Pharmacologically Active Compounds for the Identification of Novel Candidate Drugs for KMT2A-Rearranged Leukemia Karsa, Mawar; Ronca, Emma; Bongers, Angelika; Mariana, Anna; Moles, Ernest; Failes, Timothy W.; Arndt, Greg M.; Cheung, Laurence C.; Kotecha, Rishi S.; Kavallaris, Maria; Haber, Michelle; Norris, Murray D.; Henderson, Michelle J.; Xiao, Lin; Somers, Klaartje 分享 收藏
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The impact of ExHp-CD (outer membrane vesicles) released from Helicobacter pylori SS1 on macrophage RAW 264.7 cells and their immunogenic potential Ahmed, Abeer Ahmed Qaed; Qi, Fuyu; Zheng, Ruizhu; Xiao, Lin; Abdalla, Ahmed M. E.; Mao, Lin; Bakadia, Bianza Moise; Liu, Li; Atta, Omar Mohammad; Li, Xiaohong; Shi, Zhijun; Yang, Guang 分享 收藏
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DJ-1 is involved in the multidrug resistance of SGC7901 gastric cancer cells through PTEN/PI3K/Akt/Nrf2 pathway DJ-1通过PTEN/PI3K/Akt/Nrf2通路参与SGC7901胃癌细胞的多药耐药 Qiu, Lejia; Ma, Zhaoxia; Li, Xiaoran; Deng, Yizhang; Duan, Guangling; Zhao, L. E.; Xu, Xingwang; Xiao, Lin; Liu, Haoyue; Zhu, Zhengming; Chen, Heping 分享 收藏
Electroporation of NKG2D RNA CAR Improves Vγ9Vδ2 T Cell Responses against Human Solid Tumor Xenografts Ang, Wei Xia; Ng, Yu Yang; Xiao, Lin; Chen, Can; Li, Zhendong; Chi, Zhixia; Tay, Johan Chin-Kang; Tan, Wee Kiat; Zeng, Jieming; Toh, Han Chong; Wang, Shu 分享 收藏
LINC00173.v1 promotes angiogenesis and progression of lung squamous cell carcinoma by sponging miR-511-5p to regulate VEGFA expression Chen, Jiarong; Liu, Aibin; Wang, Zhihui; Wang, Bin; Chai, Xingxing; Lu, Wenjie; Cao, Ting; Li, Ronggang; Wu, Minyan; Lu, Zhuming; Pang, Wenguang; Xiao, Lin; Chen, Xiangmeng; Zheng, Yan; Chen, Qiong; Zeng, Jincheng; Li, Jun; Zhang, Xin; Ren, Dong; Huang, Yanming 分享 收藏
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