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T

Tatu Pantsar

University of Eastern Finland
H指数:15
被引数:2,431

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荣誉奖项

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PIP4K2C inhibition reverses autophagic flux impairment induced by SARS-CoV-2

Karim, M.; Mishra, M.; Lo, C.W.; Saul, S.; Cagirici, H.; Gourdelier, M.; Ghita, L.; Ojha, A.; Tran, D.H.N.; Agrawal, A.; et al. PIP4K2C抑制逆转由SARS-CoV-2引起的自噬流障碍。Nat. Commun. 2025, 16, 6397. [Google Scholar] [CrossRef]

Nature Communications
IF15.7
2025-07-100
OAAI
Marwah Karim; Manjari Mishra; Chieh-Wen Lo; Sirle Saul; Halise Busra Cagirici; Manon Gourdelier; Luca Ghita; Amrita Ojha; Do Hoang Nhu Tran; Aditi Agrawal; Connor McGraw; Michael P. East; Karen Anbro Gammeltoft; Malaya Kumar Sahoo; Nancie A. Mooney; Gary L. Johnson; Soumita Das; Pieter Leyssen; Johan Neyts; Winston Chiu; Courtney A. Cohen; Jens Bukh; Judith Gottwein; John M. Dye; Norma Neff; Peter K. Jackson; Benjamin A. Pinsky; Tuomo Laitinen; Tatu Pantsar; Antti Poso; Fabio Zanini; Steven De Jonghe; Christopher R. M. Asquith; Shirit Einav
Beyond KRAS(G12C): Biochemical and Computational Characterization of Sotorasib and Adagrasib Binding Specificity and the Critical Role of H95 and Y96

超越KRAS(G12C): Sotorasib和Adagrasib结合特异性的生化和计算表征以及H95和Y96的关键作用

ACS CHEMICAL BIOLOGY
IF3.8
2024-09-161
PRE
Mahran, Randa; Kapp, Jonas N.; Valtonen, Salla; Champagne, Allison; Ning, Jinying; Gillette, William; Stephen, Andrew G.; Hao, Feng; Pluckthun, Andreas; Harma, Harri; Pantsar, Tatu; Kopra, Kari
Development and characterization of kinase sparing TPX2-tethering Aurora kinase A ligands for cancer therapy
CANCER RESEARCH
IF16.6
2024-03-220
PRE
Moschopoulou, Athina Anastasia; Henning, Melanie; Wagner, Benedikt; Flotgen, Dirk; Reiner, Juliander; Skliarenko, Yulia; Zwirner, Stefan; Hinterleitner, Clemens; Seehawer, Marco; dArtista, Luana; Rist, Elke; Pantsar, Tatu; Kronenberger, Thales; Dauch, Daniel; Gehring-Khav, Corinna; Poso, Antti; Andreeva, Liudmila; Schwab, Matthias; Forster, Michael; Albrecht, Wolfgang; Laufer, Stefan; Zender, Lars
Discovery and Development of First-in-Class ACKR3/CXCR7 Superagonists for Platelet Degranulation Modulation

用于血小板脱颗粒调节的一流ACKR3/CXCR7超激动剂的发现和开发

JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2022-09-237
PRE
Bayrak, Alp; Mohr, Florian; Kolb, Kyra; Szpakowska, Martyna; Shevchenko, Ekaterina; Dicenta, Valerie; Rohlfing, Anne-Katrin; Kudolo, Mark; Pantsar, Tatu; Guenther, Marcel; Kaczor, Agnieszka A.; Poso, Antti; Chevigne, Andy; Pillaiyar, Thanigaimalai; Gawaz, Meinrad; Laufer, Stefan A.
Bioisosteric Replacement of Arylamide-Linked Spine Residues with N-Acylhydrazones and Selenophenes as a Design Strategy to Novel Dibenzosuberone Derivatives as Type I 1/2 p38α MAP Kinase Inhibitors

用N-酰基hydr和硒酚生物等排取代芳基酰胺连接的脊柱残基，作为新型二苯并环酮衍生物作为I型1/2 p38α MAP激酶抑制剂的设计策略

JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2020-05-2814
PREAI
Pedreira, Julia G. B.; Nahidino, Philipp; Kudolo, Mark; Pantsar, Tatu; Berger, Benedict-Tilman; Forster, Michael; Knapp, Stefan; Laufer, Stefan; Barreiro, Eliezer J.
Design, synthesis, and biological evaluation of 2,4-dihydropyrano[2,3-c]pyrazole derivatives as autotaxin inhibitors

自分泌运动因子抑制剂2，4-二氢吡喃并 [2，3-c] 吡唑衍生物的设计、合成及生物学评价

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
IF4.7
2017-09-0111
PREAI
Pantsar, Tatu; Singha, Prosanta; Nevalainen, Tapio J.; Koshevoy, Igor; Leppanen, Jukka; Poso, Antti; Niskanen, Juha M. A.; Pasonen-Seppanen, Sanna; Savinainen, Juha R.; Laitinen, Tuomo; Laitinen, Jarmo T.
A MYC-aurora kinase A protein complex represents an actionable drug target in p53-altered liver cancer

Myc-aurora激酶A蛋白复合物代表p53-altered肝癌的可行药物靶标

NATURE MEDICINE
IF50
2016-05-23223
PREAI
Dauch, Daniel; Rudalska, Ramona; Cossa, Giacomo; Nault, Jean-Charles; Kang, Tae-Won; Wuestefeld, Torsten; Hohmeyer, Anja; Imbeaud, Sandrine; Yevsa, Tetyana; Hoenicke, Lisa; Pantsar, Tatu; Bozko, Przemyslaw; Malek, Nisar P.; Longerich, Thomas; Laufer, Stefan; Poso, Antti; Zucman-Rossi, Jessica; Eilers, Martin; Zender, Lars

研究方向

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S
Stefan Laufer
H 指数:70论文数:823被引数:2.0万
A
Antti Poso
H 指数:46论文数:413被引数:7,695
M
Mark Kudolo
H 指数:13论文数:54被引数:395
T
Tuomo Laitinen
H 指数:29论文数:209被引数:2,398
M
Michael Förster
H 指数:17论文数:52被引数:966
P
Pierre Koch
H 指数:23论文数:152被引数:1,679
F
Francesco Ansideri
H 指数:9论文数:35被引数:301
M
Matthias Schwab
H 指数:122论文数:1,356被引数:7.0万
W
Wolfgang Albrecht
H 指数:24论文数:119被引数:2,946
J
Juha R. Savinainen
H 指数:26论文数:68被引数:2,214