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Combination of bazedoxifene with chemotherapy and SMAC-mimetics for the treatment of colorectal cancer (vol 15, 255, 2024) 唑来膦酸与化疗及SMAC模拟物联合治疗结直肠癌(卷15,255,2024) Dmello, Rhynelle S.; Palmieri, Michelle; Thilakasiri, Pathum S.; Doughty, Larissa; Nero, Tracy L.; Poh, Ashleigh R.; To, Sarah Q.; Lee, Erinna F.; Fairlie, W. Douglas; Mielke, Lisa; Parker, Michael W.; Poon, Ivan K. H.; Batlle, Eduard; Ernst, Matthias; Chand, Ashwini L. 分享 收藏
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In situ visualization of endothelial cell-derived extracellular vesicle formation in steady state and malignant conditions Atkin-Smith, Georgia K.; Santavanond, Jascinta P.; Light, Amanda; Rimes, Joel S.; Samson, Andre L.; Er, Jeremy; Liu, Joy; Johnson, Darryl N.; Le Page, Melanie; Rajasekhar, Pradeep; Yip, Raymond K. H.; Geoghegan, Niall D.; Rogers, Kelly L.; Chang, Catherine; Bryant, Vanessa L.; Margetts, Mai; Keightley, M. Cristina; Kilpatrick, Trevor J.; Binder, Michele D.; Tran, Sharon; Lee, Erinna F.; Fairlie, Walter D.; Ozkocak, Dilara C.; Wei, Andrew H.; Hawkins, Edwin D.; Poon, Ivan K. H. 分享 收藏
Combination of bazedoxifene with chemotherapy and SMAC-mimetics for the treatment of colorectal cancer Dmello, Rhynelle S.; Palmieri, Michelle; Thilakasiri, Pathum S.; Doughty, Larissa; Nero, Tracy L.; Poh, Ashleigh R.; To, Sarah Q.; Lee, Erinna F.; Fairlie, W. Douglas; Mielke, Lisa; Parker, Michael W.; Poon, Ivan K. H.; Batlle, Eduard; Ernst, Matthias; Chand, Ashwini L. 分享 收藏
BCL-XL inhibitors enhance the apoptotic efficacy of BRAF inhibitors in BRAFV600E colorectal cancer Jenkins, Laura J.; Luk, Ian Y.; Chionh, Fiona; Tan, Tao; Needham, Kristen; Ayton, Jamieson; Reehorst, Camilla M.; Vukelic, Natalia; Sieber, Oliver M.; Mouradov, Dmitri; Gibbs, Peter; Williams, David S.; Tebbutt, Niall C.; Desai, Jayesh; Hollande, Frederic; Dhillon, Amardeep S.; Lee, Erinna F.; Merino, Delphine; Fairlie, W. Douglas; Mariadason, John M. 分享 收藏
BECLIN1 is essential for intestinal homeostasis involving autophagy-independent mechanisms through its function in endocytic trafficking BECLIN1通过其在内细胞运输中的功能对涉及自噬非依赖性机制的肠道稳态至关重要 Tran, Sharon; Juliani, Juliani; Harris, Tiffany J.; Evangelista, Marco; Ratcliffe, Julian; Ellis, Sarah L.; Baloyan, David; Reehorst, Camilla M.; Nightingale, Rebecca; Luk, Ian Y.; Jenkins, Laura J.; Ghilas, Sonia; Yakou, Marina H.; Inguanti, Chantelle; Johnson, Chad; Buchert, Michael; Lee, James C.; De Cruz, Peter; Duszyc, Kinga; Gleeson, Paul A.; Kile, Benjamin T.; Mielke, Lisa A.; Yap, Alpha S.; Mariadason, John M.; Douglas Fairlie, W.; Lee, Erinna F. 分享 收藏
Modular synthesis of functional libraries by accelerated SuFEx click chemistry Homer, Joshua A.; Koelln, Rebecca A.; Barrow, Andrew S.; Gialelis, Timothy L.; Boiarska, Zlata; Steinohrt, Nikita S.; Lee, Erinna F.; Yang, Wen-Hsuan; Johnson, Robert M.; Chung, Taemoon; Habowski, Amber N.; Vishwakarma, Dharmendra S.; Bhunia, Debmalya; Avanzi, Charlotte; Moorhouse, Adam D.; Jackson, Mary; Tuveson, David A.; Lyons, Scott K.; Lukey, Michael J.; Fairlie, W. Douglas; Haider, Shozeb M.; Steinmetz, Michel O.; Prota, Andrea E.; Moses, John E. 分享 收藏
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Genotype-Tailored ERK/MAPK Pathway and HDAC Inhibition Rewires the Apoptotic Rheostat to Trigger Colorectal Cancer Cell Death Jenkins, Laura J.; Luk, Ian Y.; Fairlie, W. Douglas; Lee, Erinna F.; Palmieri, Michelle; Schoffer, Kael L.; Tan, Tao; Ng, Irvin; Vukelic, Natalia; Tran, Sharon; Tse, Janson W. T.; Nightingale, Rebecca; Alam, Zakia; Chionh, Fiona; Iatropoulos, George; Ernst, Matthias; Afshar-Sterle, Shoukat; Desai, Jayesh; Gibbs, Peter; Sieber, Oliver M.; Dhillon, Amardeep S.; Tebbutt, Niall C.; Mariadason, John M. 分享 收藏
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BCL-XL is an actionable target for treatment of malignant pleural mesothelioma (vol 6, 114, 2020) Arulananda, Surein; O'Brien, Megan; Evangelista, Marco; Harris, Tiffany J.; Steinohrt, Nikita S.; Jenkins, Laura J.; Walkiewicz, Marzena; O'Donoghue, Robert J. J.; Poh, Ashleigh R.; Thapa, Bibhusal; Williams, David S.; Leong, Trishe; Mariadason, John M.; Li, Xia; Cebon, Jonathan; Lee, Erinna F.; John, Thomas; Fairlie, W. Douglas 分享 收藏
A novel BH3-mimetic, AZD0466, targeting BCL-XL and BCL-2 is effective in pre-clinical models of malignant pleural mesothelioma Arulananda, Surein; O'Brien, Megan; Evangelista, Marco; Jenkins, Laura J.; Poh, Ashleigh R.; Walkiewicz, Marzena; Leong, Trishe; Mariadason, John M.; Cebon, Jonathan; Balachander, Srividya B.; Cidado, Justin R.; Lee, Erinna F.; John, Thomas; Fairlie, Walter D. 分享 收藏
Optimization of Benzothiazole and Thiazole Hydrazones as Inhibitors of Schistosome BCL-2 Nguyen, William; Lee, Erinna F.; Evangelista, Marco; Lee, Mihwa; Harris, Tiffany J.; Colman, Peter M.; Smith, Nicholas A.; Williams, Luke B.; Jarman, Kate E.; Lowes, Kym N.; Haeberli, Cecile; Keiser, Jennifer; Smith, Brian J.; Fairlie, W. Douglas; Sleebs, Brad E. 分享 收藏
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BCL-XL is an actionable target for treatment of malignant pleural mesothelioma Arulananda, Surein; O'Brien, Megan; Evangelista, Marco; Harris, Tiffany J.; Steinohrt, Nikita S.; Jenkins, Laura J.; Walkiewicz, Marzena; O'Donoghue, Robert J. J.; Poh, Ashleigh R.; Thapa, Bibhusal; Williams, David S.; Leong, Trishe; Mariadason, John M.; Li, Xia; Cebon, Jonathan; Lee, Erinna F.; John, Thomas; Douglas Fairlie, W. 分享 收藏