logo
科言猫学术研究的AI总结
language
手机端手机端
  • Phone Feature微信小程序
简体中文简体中文
notice消息通知
博客博客
arrow
G

Guillaume Lessène

University of Melbourne
H指数:47
被引数:1.4万

个人简介

暂无内容

教育背景

暂无内容

工作经历

暂无内容

荣誉奖项

暂无内容

Re-appraising assays on permeabilized blood cancer cells testing venetoclax or other BH3 mimetic agents selectively targeting pro-survival BCL2 proteins

对渗透的血癌细胞进行再评估试验，测试维奈克拉或选择性靶向促生存BCL2蛋白的其他BH3模拟剂

CELL DEATH AND DIFFERENTIATION
IF15.4
2025-04-090
OA
Gong, Jia-Nan; Djajawi, Tirta M.; Moujalled, Donia M.; Pomilio, Giovanna; Khong, Tiffany; Zhang, Li-Ping; Fedele, Pasquale L.; Low, Michael S.; Anderson, Mary Ann; Riffkin, Christopher D.; White, Christine A.; Lan, Ping; Lessene, Guillaume; Herold, Marco J.; Strasser, Andreas; Spencer, Andrew; Grigoriadis, George; Wei, Andrew H.; van Delft, Mark F.; Roberts, Andrew W.; Huang, David C. S.
The anti-cancer agent APR-246 can activate several programmed cell death processes to kill malignant cells (Feb,10.1038/s41418-023-01122-3, 2023)
CELL DEATH AND DIFFERENTIATION
IF15.4
2023-02-240
OAAI
Wang, Zilu; Hu, Huimin; Heitink, Luuk; Rogers, Kelly; You, Yue; Tan, Tao; Suen, Connie Li Wai; Garnham, Alex; Chen, Hao; Lieschke, Elizabeth; Diepstraten, Sarah T.; Chang, Catherine; Chen, Tianwei; Moujalled, Diane; Sutherland, Kate; Lessene, Guillaume; Sieber, Oliver M.; Visvader, Jane; Kelly, Gemma L.; Strasser, Andreas
Development of NanoLuc-targeting protein degraders and a universal reporter system to benchmark tag-targeted degradation platforms
NATURE COMMUNICATIONS
IF15.7
2022-04-1916
OAAI
Grohmann, Christoph; Magtoto, Charlene M.; Walker, Joel R.; Chua, Ngee Kiat; Gabrielyan, Anna; Hall, Mary; Cobbold, Simon A.; Mieruszynski, Stephen; Brzozowski, Martin; Simpson, Daniel S.; Dong, Hao; Dorizzi, Bridget; Jacobsen, Annette, V; Morrish, Emma; Silke, Natasha; Murphy, James M.; Heath, Joan K.; Testa, Andrea; Maniaci, Chiara; Ciulli, Alessio; Lessene, Guillaume; Silke, John; Feltham, Rebecca
Insights Into Drug Repurposing, as Well as Specificity and Compound Properties of Piperidine-Based SARS-CoV-2 PLpro Inhibitors

洞察药物再利用，以及基于哌啶的SARS-CoV-2 PLpro抑制剂的特异性和复合特性

FRONTIERS IN CHEMISTRY
IF4.2
2022-04-1222
OAAI
Calleja, Dale J.; Kuchel, Nathan; Lu, Bernadine G. C.; Birkinshaw, Richard W.; Klemm, Theresa; Doerflinger, Marcel; Cooney, James P.; Mackiewicz, Liana; Au, Amanda E.; Yap, Yu Q.; Blackmore, Timothy R.; Katneni, Kasiram; Crighton, Elly; Newman, Janet; Jarman, Kate E.; Call, Melissa J.; Lechtenberg, Bernhard C.; Czabotar, Peter E.; Pellegrini, Marc; Charman, Susan A.; Lowes, Kym N.; Mitchell, Jeffrey P.; Nachbur, Ueli; Lessene, Guillaume; Komander, David
BCL-XL antagonism selectively reduces neutrophil life span within inflamed tissues without causing neutropenia
BLOOD ADVANCES
IF7.1
2021-06-0812
OA
Carrington, Emma M.; Louis, Cynthia; Kratina, Tobias; Hancock, Manuela; Keenan, Christine R.; Iannarella, Nadia; Allan, Rhys S.; Wardak, Ahmad Z.; Czabotar, Peter E.; Herold, Marco J.; Schenk, Robyn L.; White, Christine A.; D'Silva, Damian; Yang, Yuyan; Wong, Wesley; Wong, Huon; Bryant, Vanessa L.; Huntington, Nicholas D.; Rautela, Jai; Sutherland, Robyn M.; Zhan, Yifan; Hansen, Jacinta; Duong Nhu; Lessene, Guillaume; Wicks, Ian P.; Lew, Andrew M.
Preclinical small molecule WEHI-7326 overcomes drug resistance and elicits response in patient-derived xenograft models of human treatment-refractory tumors
CELL DEATH & DISEASE
IF9.6
2021-03-122
OAAI
Grohmann, Christoph; Walker, Francesca; Devlin, Mark; Luo, Meng-Xiao; Chueh, Anderly C.; Doherty, Judy; Vaillant, Francois; Ho, Gwo-Yaw; Wakefield, Matthew J.; Weeden, Clare E.; Kamili, Alvin; Murray, Jayne; Po'uha, Sela T.; Weinstock, Janet; Kane, Serena R.; Faux, Maree C.; Broekhuizen, Esmee; Zheng, Ye; Shield-Artin, Kristy; Kershaw, Nadia J.; Tan, Chin Wee; Witchard, Helen M.; Ebert, Gregor; Charman, Susan A.; Street, Ian; Kavallaris, Maria; Haber, Michelle; Fletcher, Jamie I.; Asselin-Labat, Marie-Liesse; Scott, Clare L.; Visvader, Jane E.; Lindeman, Geoffrey J.; Watson, Keith G.; Burgess, Antony W.; Lessene, Guillaume
Synthesis and Biological Evaluation of (-) and (+)-Spiroleucettadine and Analogues
CHEMMEDCHEM
IF3.4
2021-01-260
PREAI
Badart, Michael P.; Barnes, Emma M.; Cording, Andrew P.; Gilmer, Selena C. L.; Billinghurst, Ian D.; Edupuganti, Veera V. Shivaji R.; Lessene, Guillaume; Bland, Abigail R.; Bower, Rebekah L.; Rana, Zohaib; Ferguson, Scott A.; Opel Reading, Helen K.; Cook, Gregory M.; Rosengren, Rhonda J.; Krause, Kurt L.; Gamble, Allan B.; Ashton, John C.; Hawkins, Bill C.

研究方向

暂未获取到该数据
P
Peter E. Czabotar
H 指数:62论文数:216被引数:2.6万
D
David C.S. Huang
H 指数:101论文数:577被引数:4.5万
J
James M. Murphy
H 指数:89论文数:488被引数:2.6万
J
John Silke
H 指数:91论文数:370被引数:3.6万
K
Kym N. Lowes
H 指数:23论文数:65被引数:3,875
P
Peter M. Colman
H 指数:65论文数:195被引数:2.2万
A
Andreas Strasser
H 指数:135论文数:816被引数:8.4万
B
Brian J. Smith
H 指数:70论文数:358被引数:1.9万
J
Jonathan B. Baell
H 指数:52论文数:352被引数:1.5万
M
Mark F. van Delft
H 指数:25论文数:51被引数:6,879