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J

John Alexander

The Institute of Cancer Research
H指数:33
被引数:4,426

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荣誉奖项

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The anion channel GPR89 is a tumor-specific dependency in breast cancer

GPR89阴离子通道是乳腺癌的肿瘤特异性依赖

Nature Communications
IF15.7
2026-08-240
OA
Riccardo Ferro; Alexandra Carroll; Ana M. Mendes-Pereira; Virinder Reen; George Vlachogiannis; Rebeca Uceda-Castro; Dragomir Krastev; Valeria Amodeo; Stephen Pettitt; Nadja D’Uonno; Ioanna Mavrommati; Blanca Navarro; Luke Hitchen; Jennifer Trendell; Ana Stojiljkovic; Cynthia Prince; Narinder Janghra; Ioannis Roxanis; Patrycja Gazinska; Daniel Larcombe-Young; Rebecca Marlow; Stefano Annunziato; Jos Jonkers; Tejashree Rajaram Kanitkar; Amadeus Xu; Nirmesh Patel; Nalan Liv; John Alexander; Jelmar Quist; Mercedes Pardo; Theodoros I. Roumeliotis; Jyoti S. Choudhary; Daniel Weekes; Pierfrancesco Marra; Joanna I. Loizou; Rachael Natrajan; Anita Grigoriadis; Mallur Srivatsan Madhusudhan; Syed Haider; Christopher J. Lord; Andrew Tutt
ClinGen recuration of hearing loss-associated genes demonstrates significant changes in gene-disease validity over time

ClinGen对听力损失相关基因的再注释表明基因-疾病有效性随时间发生显著变化

Genetics in Medicine
IF6.2
2025-09-070
PREAI
Kezang C. Tshering; Marina T. DiStefano; Andrea M. Oza; Pamela Ajuyah; Ryan Webb; Enyonam Edoh; Ellie Broeren; Julie Ratliff; Vanessa Gitau; Kelley Paris; Amal Aburyyan; John Alexander; Victoria Albano; Donglin Bai; Kevin T.A. Booth; Paula I. Buonfiglio; Cherine Charfeddine; Viviana Dalamón; Ignacio del Castillo; Miguel Angel Moreno-Pelayo; Hatice Duzkale; Ben Dorshorst; Rabia Faridi; Margaret Kenna; Morag A. Lewis; Minjie Luo; Yu Lu; Rahma Mkaouar; Tatsuo Matsunaga; Kiyomitsu Nara; Arti Pandya; Shelby Redfield; Isabelle Roux; Lisa A. Schimmenti; Isabelle Schrauwen; Sherin Shaaban; Jun Shen; Barbara Vona; Richard J. Smith; Heidi L. Rehm; Hela Azaiez; Ahmad N. Abou Tayoun; Sami S. Amr
A RIPK1-specific PROTAC degrader achieves potent antitumor activity by enhancing immunogenic cell death

RIPK1-specific的PROTAC降解剂通过增强免疫原性细胞死亡来实现有效的抗肿瘤活性

IMMUNITY
IF26.3
2024-07-013
OA
Mannion, Jonathan; Gifford, Valentina; Bellenie, Benjamin; Fernando, Winnie; Garcia, Laura Ramos; Wilson, Rebecca; John, Sidonie Wicky; Udainiya, Savita; Patin, Emmanuel C.; Tiu, Crescens; Smith, Angel; Goicoechea, Maria; Craxton, Andrew; Vasconcelos, Nathalia Moraes de; Cheung, Kwai-Ming J.; Cundy, Nicholas J.; Pierrat, Olivier; Brennan, Alfie; Benstead-Hume, Graeme; Roumeliotis, Theodoros I.; Alexander, John; Muirhead, Gareth; Layzell, Scott; Lyu, Wenxin; Roulstone, Victoria; Baldock, Holly; Legrand, Arnaud; Gabel, Florian; Serrano-Aparicio, Natalia; Starling, Chris; Guo, Hongyan; Upton, Jason; Gyrd-Hansen, Mads; Seddon, Benedict; Roxanis, Ioannis; Harrington, Kevin; Haider, Syed; Choudhary, Jyoti S.; Haider, Swen; Tenev, Tencho; Meier, Pascal
MND1 and PSMC3IP control PARP inhibitor sensitivity in mitotic cells

MND1和PSMC3IP控制有丝分裂细胞的PARP抑制剂敏感性

CELL REPORTS
IF6.9
2023-05-013
OA
Zelceski, Anabel; Francica, Paola; Lingg, Lea; Mutlu, Merve; Stok, Colin; Liptay, Martin; Alexander, John; Baxter, Joseph S.; Brough, Rachel; Gulati, Aditi; Haider, Syed; Raghunandan, Maya; Song, Feifei; Sridhar, Sandhya; Forment, Josep, V; O'Connor, Mark J.; Davies, Barry R.; van Vugt, Marcel A. T. M.; Krastev, Dragomir B.; Pettitt, Stephen J.; Tutt, Andrew N. J.; Rottenberg, Sven; Lord, Christopher J.
Longitudinal analysis of PARP inhibitor and platinum resistance in BRCA1/2m breast cancer using liquid biopsy
CANCER RESEARCH
IF16.6
2023-04-043
PRE
Harvey-Jones, Elizabeth; Raghunandan, Maya; Robbez-Masson, Luisa; Thanussuyah, Alaguthurai; Liccardo, Roberta; Yablonovitch, Arielle; Cai, Mingyang; Drusbosky, Leylah; Dorschner, Michael; Pardo, Lorena Magraner; Marlow, Rebecca; Konde, Asha; Trendell, Jennifer; Alexander, John; Haider, Syed; Starling, Chris; Roxanis, Ioannis; Yen, Jennifer; Pettitt, Stephen J.; Lord, Christopher J.; Tutt, Andrew N.
SMG8/SMG9 Heterodimer Loss Modulates SMG1 Kinase to Drive ATR Inhibitor Resistance
CANCER RESEARCH
IF16.6
2022-10-237
OAAI
Llorca-Cardenosa, Marta J.; Aronson, Lauren I.; Krastev, Dragomir B.; Nieminuszczy, Jadwiga; Alexander, John; Song, Feifei; Dylewska, Malgorzata; Broderick, Ronan; Brough, Rachel; Zimmermann, Astrid; Zenke, Frank T.; Gurel, Bora; Riisnaes, Ruth; Ferreira, Ana; Roumeliotis, Theodoros; Choudhary, Jyoti; Pettitt, Stephen J.; de Bono, Johann; Cervantes, Andres; Haider, Syed; Niedzwiedz, Wojciech; Lord, Christopher J.; Chong, Irene Y.
The Mutational Concordance of Fixed Formalin Paraffin Embedded and Fresh Frozen Gastro-Oesophageal Tumours Using Whole Exome Sequencing

使用全外显子组测序固定的福尔马林石蜡包埋和新鲜冷冻的胃食管肿瘤的突变一致性

JOURNAL OF CLINICAL MEDICINE
IF2.9
2021-01-098
OAAI
Chong, Irene Y.; Starling, Naureen; Rust, Alistair; Alexander, John; Aronson, Lauren; Llorca-Cardenosa, Marta; Chauhan, Ritika; Chaudry, Asif; Kumar, Sacheen; Fenwick, Kerry; Assiotis, Ioannis; Matthews, Nik; Begum, Ruwaida; Wotherspoon, Andrew; Terlizzo, Monica; Watkins, David; Chau, Ian; Lord, Christopher J.; Haider, Syed; Rao, Sheela; Cunningham, David
Epilepsy and Electroencephalographic Abnormalities in SATB2-Associated Syndrome
PEDIATRIC NEUROLOGY
IF2.1
2020-11-0113
OAAI
Lewis, Hannah; Samanta, Debopam; Orsell, Jenny-Li; Bosanko, Katherine A.; Rowell, Amy; Jones, Melissa; Dale, Russell C.; Taravath, Sasidharan; Hahn, Cecil D.; Krishnakumar, Deepa; Chagnon, Sarah; Keller, Stephanie; Hagebeuk, Eveline; Pathak, Sheel; Bebin, E. Martina; Arndt, Daniel H.; Alexander, John J.; Mainali, Gayatra; Coppola, Giangennaro; Maclean, Jane; Sparagana, Steven; McNamara, Nancy; Smith, Douglas M.; Raggio, Victor; Cruz, Marcos; Fernandez-Jaen, Alberto; Kava, Maina P.; Emrick, Lisa; Fish, Jennifer L.; Vanderver, Adeline; Helman, Guy; Pierson, Tyler M.; Zarate, Yuri A.

研究方向

暂未获取到该数据
S
Syed Haider
H 指数:52论文数:432被引数:1.4万
C
Christopher J. Lord
H 指数:98论文数:710被引数:4.5万
S
Stephen J. Pettitt
H 指数:31论文数:216被引数:5,721
A
Andrew Tutt
H 指数:103论文数:781被引数:8.7万
R
Rachel Brough
H 指数:35论文数:264被引数:9,652
D
Dragomir B. Krastev
H 指数:18论文数:109被引数:3,045
F
Feifei Song
H 指数:11论文数:54被引数:1,360
J
Jyoti S. Choudhary
H 指数:69论文数:458被引数:2.6万
T
Theodoros I. Roumeliotis
H 指数:30论文数:191被引数:4,774
C
Clare M. Isacke
H 指数:63论文数:472被引数:1.1万