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S

Scott A. Foster

genentech, inc.
H指数:38
被引数:6,797

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Chemically-induced degradation of the endoplasmic-reticulum stress sensor IRE1 by a VHL-recruiting chimera

化学诱导的内质网应激传感器IRE1的降解，通过一种VHL招募嵌合体实现

Nature Communications
IF15.7
2025-12-110
OA
Jin Du; Elisia Villemure; Matthew Johnson; Caleigh Azumaya; Catarina J. Gaspar; Scot Marsters; David Lawrence; Scott Foster; Alexis Rohou; Tommy K. Cheung; Christopher M. Rose; Thomas Garner; Soo Ro; Kevin Clark; Maureen H. Beresini; Marie-Gabrielle Braun; Joachim Rudolph; Peter Hsu; Avi Ashkenazi
NRF2 supports non-small cell lung cancer growth independently of CBP/p300-enhanced glutathione synthesis

NRF2支持非小细胞肺癌的生长，且该作用独立于CBP/p300增强的谷胱甘肽合成。

EMBO REPORTS
IF6.2
2025-05-140
OA
Conrad, Ryan J.; Mondo, James A.; Wang, Mike Lingjue; Liu, Peter S.; Lai, Zijuan; Choudhury, Feroza K.; Li, Qingling; Wong, Weng Ruh; Lee, James; Shanahan, Frances; Lin, Eva; Martin, Scott; Rudolph, Joachim; Moffat, John G.; Sangaraju, Dewakar; Sandoval, Wendy; Sterne-Weiler, Timothy; Foster, Scott A.
Targeted degradation via direct 26S proteasome recruitment
NATURE CHEMICAL BIOLOGY
IF13.7
2022-12-2838
OAAI
Bashore, Charlene; Prakash, Sumit; Johnson, Matthew C.; Conrad, Ryan J.; Kekessie, Ivy A.; Scales, Suzie J.; Ishisoko, Noriko; Kleinheinz, Tracy; Liu, Peter S.; Popovych, Nataliya; Wecksler, Aaron T.; Zhou, Lijuan; Tam, Christine; Zilberleyb, Inna; Srinivasan, Rajini; Blake, Robert A.; Song, Aimin; Staben, Steven T.; Zhang, Yingnan; Arnott, David; Fairbrother, Wayne J.; Foster, Scott A.; Wertz, Ingrid E.; Ciferri, Claudio; Dueber, Erin C.

研究方向

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S
Shiva Malek
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B
Brian A. Johns
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Randall Lanier
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A
Akihiko Sato
H 指数:51论文数:481被引数:1.1万
T
Tomokazu Yoshinaga
H 指数:21论文数:41被引数:2,489
J
Joachim Rudolph
H 指数:37论文数:169被引数:4,951
D
David O. Morgan
H 指数:83论文数:300被引数:3.5万
T
Tamio Fujiwara
H 指数:35论文数:121被引数:6,190
V
Varun V. Prabhu
H 指数:28论文数:362被引数:2,873