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K

Karthik Venkatakrishnan

EMD Serono Research and Development Institute Inc

49H指数
330论文数
9.4K被引数
收录论文 133
发表时间
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Empowering Clinical Development With Disease Progression Modeling: Recommendations From the Clinical Trials Transformation Initiative通过疾病进展建模赋能临床试验开发：临床研究转型倡议的推荐
errCTS-Clinical and Translational Science
IF2.8
err2026-09-20
err0
errOAAI
errLindsay S. Kehoe; Shu Chin Ma; Jiang Liu; Qi Liu; Herbert Pang; Bruce Burnett; Reem Yunis; Karthik Venkatakrishnan
err分享
err收藏
Acoustic Microbots: Linking Fabrication Techniques to Acoustic Actuation Mechanisms—A Systematic Review声学微机器人：连接制造技术与声学驱动机制——一项系统综述
errJournal of Field Robotics
IF5.2
err2026-08-30
err0
PREAI
errSubhashree Das; Karthik Venkatakrishnan; Anish Pandey; Pramod Kumar Malik
err分享
err收藏
An Integrated Nonclinical and Clinical Risk Assessment of the Effects of Investigational ATRi Tuvusertib on QTc Interval in Patients With Solid TumorsATR抑制剂Tuvusertib对实体瘤患者QTc间期影响的综合非临床与临床风险评估
errCTS-Clinical and Translational Science
IF2.8
err2026-02-10
err0
errOAAI
errMukker, Jatinder Kaur; Yap, Timothy A.; Tolcher, Anthony W.; de Bono, Johann S.; Plummer, Ruth; Grosser, Gary; van Amsterdam, Christoph; Schieferstein, Hanno; Witjes, Han; Diderichsen, Paul Matthias; Krebs-Brown, Axel; Gao, Wei; Strotmann, Rainer; Szucs, Zoltan; Gounaris, Ioannis; Venkatakrishnan, Karthik
err分享
err收藏
Liberty on Odaiba, Against the Silhouette of Tokyo Bay: Inspirations for Moving Hypothesis-Generating Research to Patient-Centered Therapeutics
errClinical Pharmacology & Therapeutics
IF5.5
err2026-01-19
err0
errOAAI
errKarthik Venkatakrishnan
err分享
err收藏
Innovations in Clinical Pharmacology: Shaping the Future of Evidence Generation in Research, Development, and Utilization of Medicines临床药理学创新：塑造药品研究、开发和利用中证据生成的未来
errCLINICAL PHARMACOLOGY & THERAPEUTICS
IF5.5
err2025-12-01
err0
errOAAI
errVenkatakrishnan, Karthik; Joshi, Amita; Gerding, Alethea; Giacomini, Kathleen M.; van der Graaf, Piet H.
err分享
err收藏
Integrated Population Pharmacokinetic, Pharmacodynamic, and Safety Analyses to Inform Dosage Selection in the Clinical Development of the ATR Inhibitor Tuvusertib整合群体药代动力学、药效动力学和安全性的综合分析，以指导ATR抑制剂Tuvusertib在临床开发中的剂量选择
errClinical Pharmacology & Therapeutics
IF5.5
err2025-08-21
err0
errOAAI
errJatinder Kaur Mukker; Paul Matthias Diderichsen; Farina Hellmann; Timothy A. Yap; Ruth Plummer; Anthony W. Tolcher; Johann S. de Bono; Ioannis Gounaris; Zoltan Szucs; Astrid Zimmermann; Irina Kareva; Jayaprakasam Bolleddula; Annick Seithel-Keuth; Giuseppe Locatelli; Marta Enderlin; Christine Hicking; Anup Zutshi; Wei Gao; Rainer Strotmann; Lisa Benincosa; Karthik Venkatakrishnan
err分享
err收藏
Sensitivity of Tepotinib to Inhibitors or Inducers of CYP3A4 and P-Gp: Drug Interaction Studies and Physiologically-Based Pharmacokinetic AnalysisTepotinib对CYP3A4或P-Gp抑制剂或诱导剂的敏感性：药物相互作用研究及生理药代动力学分析
errcts clinical and translational science
IF0
err2025-07-18
err0
errOAAI
errRainer Strotmann; Christian Lüpfert; Axel Krebs-Brown; Alice Ke; Matthias Boedding; Jürgen Heuer; Karen Rowland Yeo; Lisa Benincosa; Karthik Venkatakrishnan
err分享
err收藏
A Translational Model-Based Meta-Analysis to Predict Tremor Incidence Associated with Serotonin Reuptake Transporter Inhibition基于转化模型的元分析，用于预测与血清素再摄取转运蛋白抑制相关的震颤发生率
errClinical Pharmacology & Therapeutics
IF5.5
err2025-04-30
err0
PREAI
errSheetal K. Panday; Benjamin J. Lang; Georgi I. Kapitanov; Kalyanasundaram Subramanian; Lena Klopp-Schulze; Karthik Venkatakrishnan; Anup Zutshi; Abed E. Alnaif
err分享
err收藏
Model-Informed Selection of the Recommended Phase 2 Dosage for Anti-TIGIT Immunotherapy Leveraging co-Expressed PD-1 Inhibitor Target Engagement基于PD-1抑制剂靶点结合的共表达信息，指导抗TIGIT免疫疗法推荐II期剂量的模型选择
errCLINICAL PHARMACOLOGY & THERAPEUTICS
IF5.5
err2025-02-08
err0
PREAI
errKareva, Irina; Hu, Ping; Pierre, Vadryn; Kitzing, Thomas; Victor, Anja; Richter, Emilia; Gao, Wei; Venkatakrishnan, Karthik; Zutshi, Anup
err分享
err收藏
Integrated modeling of biomarkers, survival and safety in clinical oncology drug development临床肿瘤药物开发中生物标志物、生存和安全的综合建模
errADVANCED DRUG DELIVERY REVIEWS
IF17.6
err2025-01-01
err0
errOAAI
errLiu, Han; Ibrahim, Eman I. K.; Centanni, Maddalena; Sarr, Celine; Venkatakrishnan, Karthik; Friberg, Lena E.
err分享
err收藏
Asia-inclusive drug development leveraging principles of ICH E5 and E17 guidelines: Case studies illustrating quantitative clinical pharmacology as a foundational enabler
errCTS-CLINICAL AND TRANSLATIONAL SCIENCE
IF2.8
err2024-10-24
err0
errOAAI
errLu, Hong; Klopp-Schulze, Lena; Mukker, Jatinder Kaur; Li, Dandan; Kuroki, Yoshihiro; Bolleddula, Jayaprakasam; Terranova, Nadia; Goteti, Kosalaram; Gao, Wei; Strotmann, Rainer; Dong, Jennifer; Venkatakrishnan, Karthik
err分享
err收藏
Establishing a physiologically based pharmacokinetic framework for aldehyde oxidase and dual aldehyde oxidase-CYP substrates
errCPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY
IF3
err2024-10-23
err1
errOAAI
errIzat, Nihan; Bolleddula, Jayaprakasam; Carione, Pasquale; Valentin, Leticia Huertas; Jones, Robert S.; Kulkarni, Priyanka; Moss, Darren; Peterkin, Vincent C.; Tian, Dan-Dan; Treyer, Andrea; Venkatakrishnan, Karthik; Zientek, Michael A.; Barber, Jill; Houston, J. Brian; Galetin, Aleksandra; Scotcher, Daniel
err分享
err收藏
The Potential of Disease Progression Modeling to Advance Clinical Development and Decision Making
errCLINICAL PHARMACOLOGY & THERAPEUTICS
IF5.5
err2024-10-15
err0
errOAAI
errStarling, Mary Summer; Kehoe, Lindsay; Burnett, Bruce K.; Green, Phil; Venkatakrishnan, Karthik; Madabushi, Rajanikanth
err分享
err收藏
Explainable machine learning prediction of edema adverse events in patients treated with tepotinib
errCTS-CLINICAL AND TRANSLATIONAL SCIENCE
IF2.8
err2024-09-02
err0
errOAAI
errAmato, Federico; Strotmann, Rainer; Castello, Roberto; Bruns, Rolf; Ghori, Vishal; Johne, Andreas; Berghoff, Karin; Venkatakrishnan, Karthik; Terranova, Nadia
err分享
err收藏
Getting the Dosage Right: A Vital Role for Clinical Pharmacology in the Era of Precision Medicine
errCLINICAL PHARMACOLOGY & THERAPEUTICS
IF5.5
err2024-08-20
err1
errOAAI
errMinichmayr, Iris K.; Shebley, Mohamad; van Der Graaf, Piet H.; Venkatakrishnan, Karthik
err分享
err收藏
Model-informed Evidence for Clinical Non-inferiority of Every-2-Weeks Versus Standard Weekly Dosing Schedule of Cetuximab in Metastatic Colorectal Cancer
errCLINICAL PHARMACOLOGY & THERAPEUTICS
IF5.5
err2024-08-12
err0
errOAAI
errMilenkovic-Grisic, Ana-Marija; Hayes, Siobhan; Farrell, Colm; Kuroki, Yoshihiro; Bertolino, Mauro; Venkatakrishnan, Karthik; Girard, Pascal
err分享
err收藏
Moving the needle for oncology dose optimization: A call for action
errCTS-CLINICAL AND TRANSLATIONAL SCIENCE
IF2.8
err2024-06-24
err1
errOAAI
errVenkatakrishnan, Karthik; Jayachandran, Priya; Seo, Shirley K.; van Der Graaf, Piet H.; Wagner, John A.; Gupta, Neeraj
err分享
err收藏
A phase 1 study to assess the absolute bioavailability, mass balance, pharmacokinetics, metabolism, and excretion of [14C]-mobocertinib, an oral inhibitor of EGFR exon 20 insertion mutations, in healthy participants
errINVESTIGATIONAL NEW DRUGS
IF2.7
err2024-05-24
err2
errOAAI
errHanley, Michael J.; Zhang, Steven; Griffin, Robert; Zhu, Sean Xiaochun; Fram, Robert J.; Lin, Jianchang; Venkatakrishnan, Karthik; Gupta, Neeraj
err分享
err收藏
Moving the needle for oncology dose optimization: A call for action
errCPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY
IF3
err2024-05-22
err1
errOAAI
errVenkatakrishnan, Karthik; Jayachandran, Priya; Seo, Shirley K.; van der Graaf, Piet H.; Wagner, John A.; Gupta, Neeraj
err分享
err收藏
Dose Optimization in Oncology Drug Development: An International Consortium for Innovation and Quality in Pharmaceutical Development White Paper
errCLINICAL PHARMACOLOGY & THERAPEUTICS
IF5.5
err2024-05-16
err4
errOAAI
errSamineni, Divya; Venkatakrishnan, Karthik; Othman, Ahmed A.; Pithavala, Yazdi K.; Poondru, Srinivasu; Patel, Chirag; Vaddady, Pavan; Ankrom, Wendy; Ramanujan, Saroja; Budha, Nageshwar; Wu, Michael; Haddish-Berhane, Nahor; Fritsch, Holger; Hussain, Azher; Kanodia, Jitendra; Li, Meng; Li, Mengyao; Melhem, Murad; Parikh, Apurvasena; Upreti, Vijay V.; Gupta, Neeraj
err分享
err收藏

研究方向

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合作期刊
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