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SaveDiscovery of BW710 as a potent, selective and orally bioavailable fibroblast growth factor receptor 2 (FGFR2) inhibitor
Yang, Bowen; Xun, Qiuju; Tian, Yuan; Li, Huiqiong; Wu, Pinglian; Zhou, Yang; Chang, Shaohua; Wang, Zhen; Ding, Ke; Ma, Dawei Share Save Share Save 2-Oxo-3,4-dihydropyrimido[4,5-d] pyrimidines as new reversible inhibitors of EGFR C797S (Cys797 to Ser797) mutantHu, Xianglong; Xun, Qiuju; Zhang, Tao; Zhu, Su-Jie; Li, Qian; Tong, Linjiang; Lai, Mengzhen; Huang, Tao; Yun, Cai-Hong; Xie, Hua; Ding, Ke; Lu, Xiaoyun Share Save Discovery of JND3229 as a New EGFRC797S Mutant Inhibitor with In Vivo Monodrug EfficacyLu, Xiaoyun; Zhang, Tao; Zhu, Su-Jie; Xun, Qiuju; Tong, Lingjiang; Hu, Xianglong; Li, Yan; Chan, Shingpan; Su, Yi; Sun, Yiming; Chen, Yi; Ding, Jian; Yun, Cai-Hong; Xie, Hua; Ding, Ke Share Save Design, Synthesis, and Biological Evaluation of 3-(Imidazo[1,2-a]pyrazin-3-ylethynyl)-4-isopropyl-N-(3-((4-methylpiperazin-1-yl)methyl)-5-(trifluoromethyl)phenyl)benzamide as a Dual Inhibitor of Discoidin Domain Receptors 1 and 2Wang, Zhen; Zhang, Yali; Pinkas, Daniel M.; Fox, Alice E.; Luo, Jinfeng; Huang, Huocong; Cui, Shengyang; Xiang, Qiuping; Xu, Tingting; Xun, Qiuju; Zhu, Dongsheng; Tu, Zhengchao; Ren, Xiaomei; Brekken, Rolf A.; Bullock, Alex N.; Liang, Guang; Ding, Ke; Lu, Xiaoyun Share Save Design, Synthesis, and Structure-Activity Relationship Study of 2-Oxo-3,4-dihydropyrimido[4,5-d]pyrimidines as New Colony Stimulating Factor 1 Receptor (CSF1R) Kinase InhibitorsXun, Qiuju; Zhang, Zhang; Luo, Jinfeng; Tong, Linjiang; Huang, Minhao; Wang, Zhen; Zou, Jian; Liu, Yingqiang; Xu, Yong; Xie, Hua; Tu, Zheng-Chao; Lu, Xiaoyun; Ding, Ke Share Save Tetrahydroisoquinoline-7-carboxamide Derivatives as New Selective Discoidin Domain Receptor 1 (DDR1) InhibitorsWang, Zhen; Zhang, Yali; Bartual, Sergio G.; Luo, Jinfeng; Xu, Tingting; Du, Wenting; Xun, Qiuju; Tu, Zhengchao; Brekken, Rolf A.; Ren, Xiaomei; Bullock, Alex N.; Liang, Guang; Lu, Xiaoyun; Ding, Ke Share Save 
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