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Bernard Testa

University of Lausanne

77H-index
546Paper Count
2.2WCitation Count
Published Papers 90
Publication Date
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Fluoroquinolone Derivatives in the Treatment of Mycobacterium tuberculosis Infection
errPHARMACEUTICALS
IF4.8
err2022-09-30
err0
errOAAI
errPais, Joao Pedro; Policarpo, Margarida; Pires, David; Francisco, Ana Paula; Madureira, Ana Margarida; Testa, Bernard; Anes, Elsa; Constantino, Luis
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Benzoic Acid Derivatives as Prodrugs for the Treatment of Tuberculosis
errPHARMACEUTICALS
IF4.8
err2022-09-07
err6
errOAAI
errPais, Joao P.; Magalhaes, Marta; Antoniuk, Olha; Barbosa, Ivete; Freire, Raquel; Pires, David; Valente, Emilia; Testa, Bernard; Anes, Elsa; Constantino, Luis
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Activation of benzoate model prodrugs by mycobacteria. Comparison with mammalian plasma and liver hydrolysis
errEUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
IF4.7
err2021-07-01
err8
errOAAI
errValente, Emilia; Testa, Bernard; Constantino, Luis
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errSave
FAME 3: Predicting the Sites of Metabolism in Synthetic Compounds and Natural Products for Phase 1 and Phase 2 Metabolic Enzymes
errJOURNAL OF CHEMICAL INFORMATION AND MODELING
IF5.3
err2019-07-30
err63
errOAAI
errSicho, Martin; Stork, Conrad; Mazzolari, Angelica; Kops, Christina de Bruyn; Pedretti, Alessandro; Testa, Bernard; Vistoli, Giulio; Svozil, Daniel; Kirchmair, Johannes
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Prediction of UGT-mediated Metabolism Using the Manually Curated MetaQSAR Database
errACS MEDICINAL CHEMISTRY LETTERS
IF4
err2019-02-12
err12
errOAAI
errMazzolari, Angelica; Afzal, Avid M.; Pedretti, Alessandro; Testa, Bernard; Vistoli, Giulio; Bender, Andreas
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Prediction of the Formation of Reactive Metabolites by A Novel Classifier Approach Based on Enrichment Factor Optimization (EFO) as Implemented in the VEGA Program
errMOLECULES
IF4.6
err2018-11-13
err8
errOAAI
errMazzolari, Angelica; Vistoli, Giulio; Testa, Bernard; Pedretti, Alessandro
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errSave
MetaQSAR: An Integrated Database Engine to Manage and Analyze Metabolic Data
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2018-01-17
err20
PREAI
errPedretti, Alessandro; Mazzolari, Angelica; Vistoli, Giulio; Testa, Bernard
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Binding Space Concept: A New Approach To Enhance the Reliability of Docking Scores and Its Application to Predicting Butyrylcholinesterase Hydrolytic Activity
errJOURNAL OF CHEMICAL INFORMATION AND MODELING
IF5.3
err2017-07-10
err30
PREAI
errVistoli, Giulio; Mazzolari, Angelica; Testa, Bernard; Pedretti, Alessandro
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Mechanisms and pharmaceutical consequences of processes of stereoisomerisation - A didactic excursion
errEUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
IF4.7
err2016-06-01
err16
PREAI
errTesta, Bernard; Vistoli, Giulio; Pedretti, Alessandro
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Esters of Pyrazinoic Acid Are Active against Pyrazinamide-Resistant Strains of Mycobacterium tuberculosis and Other Naturally Resistant Mycobacteria In Vitro and Ex Vivo within Macrophages
errANTIMICROBIAL AGENTS AND CHEMOTHERAPY
IF4.5
err2015-12-01
err25
errOAAI
errPires, David; Valente, Emilia; Simoes, Marta Filipa; Carmo, Nuno; Testa, Bernard; Constantino, Luis; Anes, Elsa
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errSave
Predicting drug metabolism: experiment and/or computation?
errNATURE REVIEWS DRUG DISCOVERY
IF101.8
err2015-04-24
err366
PREAI
errKirchmair, Johannes; Goeller, Andreas H.; Lang, Dieter; Kunze, Jens; Testa, Bernard; Wilson, Ian D.; Glen, Robert C.; Schneider, Gisbert
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errSave
Types of stereoselectivity in drug metabolism: a heuristic approach
errDRUG METABOLISM REVIEWS
IF3.8
err2014-11-20
err15
PREAI
errTesta, Bernard
errShare
errSave
Quantitative monitoring of tamoxifen in human plasma extended to 40 metabolites using liquid-chromatography high-resolution mass spectrometry: new investigation capabilities for clinical pharmacology
errANALYTICAL AND BIOANALYTICAL CHEMISTRY
IF3.8
err2014-03-16
err32
errOAAI
errDahmane, Elyes; Boccard, Julien; Csajka, Chantal; Rudaz, Serge; Decosterd, Laurent; Genin, Eric; Duretz, Benedicte; Bromirski, Maciej; Zaman, Khalil; Testa, Bernard; Rochat, Bertrand
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Exploring the space of histidine containing dipeptides in search of novel efficient RCS sequestering agents
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2013-08-01
err15
PREAI
errVistoli, Giulio; De Maddis, Danilo; Straniero, Valentina; Pedretti, Alessandro; Pallavicini, Marco; Valoti, Ermanno; Carini, Marina; Testa, Bernard; Aldini, Giancarlo
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Chemodiversity and molecular plasticity: recognition processes as explored by property spaces
errFUTURE MEDICINAL CHEMISTRY
IF3.4
err2011-06-27
err11
PREAI
errVistoli, Giulio; Pedretti, Alessandro; Testa, Bernard
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errSave
Lipophilicity and Its Relationship with Passive Drug Permeation
errPHARMACEUTICAL RESEARCH
IF4.3
err2010-10-30
err246
PREAI
errLiu, Xiangli; Testa, Bernard; Fahr, Alfred
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errSave
Homology modeling and metabolism prediction of human carboxylesterase-2 using docking analyses by GriDock: a parallelized tool based on AutoDock 4.0
errJOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN
IF3.1
err2010-07-11
err44
PREAI
errVistoli, Giulio; Pedretti, Alessandro; Mazzolari, Angelica; Testa, Bernard
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errSave
Qualitative structure-metabolism relationships in the hydrolysis of carbamates
errDRUG METABOLISM REVIEWS
IF3.8
err2010-05-04
err63
PREAI
errVacondio, Federica; Silva, Claudia; Mor, Marco; Testa, Bernard
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In silico prediction of human carboxylesterase-1 (hCES1) metabolism combining docking analyses and MD simulations
errBIOORGANIC & MEDICINAL CHEMISTRY
IF3
err2010-01-01
err46
PREAI
errVistoli, Giulio; Pedretti, Alessandro; Mazzolari, Angelica; Testa, Bernard
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errSave
Prodrugs: bridging pharmacodynamic/pharmacokinetic gaps
errCURRENT OPINION IN CHEMICAL BIOLOGY
IF6.1
err2009-06-01
err116
PREAI
errTesta, Bernard
errShare
errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
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C. D. Marsden
H-index: 143 · Papers: 1.1K
P
Peter Jenner
H-index: 92 · Papers: 557
G
Gordon L. Amidon
H-index: 90 · Papers: 481
R
Richard H. Guy
H-index: 89 · Papers: 546
S
Sean Ekins
H-index: 83 · Papers: 710
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