Not logged in Sitravatinib in patients with solid tumors selected by molecular alterations: results from a Phase Ib study Bazhenova, Lyudmila; Kim, Dong-Wan; Cho, Byoung Chul; Goel, Sanjay; Heist, Rebecca; Werner, Theresa L.; Eaton, Keith D.; Wang, Judy S.; Pant, Shubham; Adkins, Douglas R.; Blakely, Collin M.; Yan, Xiaohong; Neuteboom, Saskia; Christensen, James G.; Chao, Richard; Bauer, Todd Share Save
Targeting multiple receptor tyrosine kinases with sitravatinib: A Phase 1b study in advanced renal cell carcinoma and castrate-resistant prostate cancer Pant, Shubham; Cho, Byoung Chul; Kyriakopoulos, Christos E.; Spira, Alexander; Tannir, Nizar; Werner, Theresa L.; Yan, Xiaohong; Neuteboom, Saskia; Chao, Richard; Goel, Sanjay Share Save
First-in-human phase 1/1b study to evaluate sitravatinib in patients with advanced solid tumors Bauer, Todd; Cho, Byong Chul; Heist, Rebecca; Bazhenova, Lyudmila; Werner, Theresa; Goel, Sanjay; Kim, Dong-Wan; Adkins, Douglas; Carvajal, Richard D.; Alva, Ajjai; Eaton, Keith; Wang, Judy; Liu, Yong; Yan, Xiaohong; Christensen, Jamie; Neuteboom, Saskia; Chao, Richard; Pant, Shubham Share Save
A first-in-human phase 1/1b study of receptor tyrosine kinase (RTK) inhibitor, MGCD516, in patients with advanced solid tumors Schwartz, G.; Adkins, D.; Heist, R.; Werner, T.; Abbott, M.; Barber, S.; Slusarz, K.; Agarwal, N.; Neuteboom, S.; Faltaos, D.; Chen, I.; Christensen, J.; Chao, R.; Bauer, T. Share Save
Synthesis and structure-activity relationships of benzophenone-bearing diketopiperazine-type anti-microtubule agents Yamazaki, Yuri; Sumikura, Makiko; Masuda, Yurika; Hayashi, Yoshiki; Yasui, Hiroyuki; Kiso, Yoshiaki; Chinen, Takumi; Usui, Takeo; Yakushiji, Fumika; Potts, Barbara; Neuteboom, Saskia; Palladino, Michael; Lloyd, George Kenneth; Hayashi, Yoshio Share Save
Synthesis and Structure-Activity Relationship Study of Antimicrotubule Agents Phenylahistin Derivatives with a Didehydropiperazine-2,5-dione Structure Yamazaki, Yuri; Tanaka, Koji; Nicholson, Benjamin; Deyanat-Yazdi, Gordafaried; Potts, Barbara; Yoshida, Tomoko; Oda, Akiko; Kitagawa, Takayoshi; Orikasa, Sumie; Kiso, Yoshiaki; Yasui, Hiroyuki; Akamatsu, Miki; Chinen, Takumi; Usui, Takeo; Shinozaki, Yuki; Yakushiji, Fumika; Miller, Brian R.; Neuteboom, Saskia; Palladino, Michael; Kanoh, Kaneo; Lloyd, George Kenneth; Hayashi, Yoshio Share Save
Phase 1 clinical trial of the novel proteasome inhibitor marizomib with the histone deacetylase inhibitor vorinostat in patients with melanoma, pancreatic and lung cancer based on in vitro assessments of the combination Millward, Michael; Price, Timothy; Townsend, Amanda; Sweeney, Christopher; Spencer, Andrew; Sukumaran, Shawgi; Longenecker, Angie; Lee, Lonnie; Lay, Ana; Sharma, Girish; Gemmill, Robert M.; Drabkin, Harry A.; Lloyd, G. Kenneth; Neuteboom, Saskia T. C.; McConkey, David J.; Palladino, Michael A.; Spear, Matthew A. Share Save
Proteasome Regulator Marizomib (NPI-0052) Exhibits Prolonged Inhibition, Attenuated Efflux, and Greater Cytotoxicity than Its Reversible Analogs Obaidat, Amanda; Weiss, Jeffrey; Wahlgren, Brett; Manam, Rama R.; Macherla, Venkat R.; McArthur, Katherine; Chao, Ta-Hsiang; Palladino, Michael A.; Lloyd, G. Kenneth; Potts, Barbara C.; Enna, Salvatore J.; Neuteboom, Saskia T. C.; Hagenbuch, Bruno Share Save
Phase 1 First-in-Human Trial of the Vascular Disrupting Agent Plinabulin (NPI-2358) in Patients with Solid Tumors or Lymphomas Mita, Monica M.; Spear, Matthew A.; Yee, Lorrin K.; Mita, Alain C.; Heath, Elisabeth I.; Papadopoulos, Kyriakos P.; Federico, Kristine C.; Reich, Steven D.; Romero, Ofelia; Malburg, Lisa; Pilat, MaryJo; Lloyd, G. Kenneth; Neuteboom, Saskia T. C.; Cropp, Gillian; Ashton, Edward; LoRusso, Patricia M. Share Save
Clinical trial combining proteasome (NPI-0052) and HDAC (vorinostat) inhibition in melanoma, pancreatic, and lung cancer Millward, Michael; Spear, Matthew A.; Townsend, Amanda; Sweeney, Christopher; Sukumaran, Shawgi; Longenecker, Angie; Palladino, Michael A.; Lloyd, G. Kenneth; Neuteboom, Saskia T.; Price, Timothy Share Save
A two-arm phase 1 clinical trial with NPI-0052, a novel proteasome inhibitor Price, Timothy; Millward, Michael; Mainwaring, Paul; Harrison, Simon; Galley, Laurence; Townsend, Amanda; Sukumaran, Shawgi; Longenecker, Angie; Palladino, Michael A.; Lloyd, G. Kenneth; Neuteboom, Saskia; Padrik, Peeter; Spear, Matthew A.; Spencer, Andrew Share Save
Leaving Groups Prolong the Duration of 20S Proteasome Inhibition and Enhance the Potency of Salinosporamides Manam, Rama Rao; McArthur, Katherine A.; Chao, Ta-Hsiang; Weiss, Jeffrey; Ali, Janid A.; Palonibella, Vito J.; Groll, Michael; Lloyd, G. Kenneth; Palladino, Michael A.; Neuteboom, Saskia T. C.; Macherla, Venkat R.; Potts, Barbara C. M. Share Save
Selective activation of liver X receptors by acanthoic acid-related diterpenes Traves, Paqui G.; Hortelano, Sonsoles; Zeini, Miriam; Chao, Ta-Hsiang; Lam, Thanh; Neuteboom, Saskia T.; Theodorakis, Emmanuel A.; Palladino, Michael A.; Castrillo, Antonio; Bosca, Lisardo Share Save
NPI-0052 enhances tumoricidal response to conventional cancer therapy in a colon cancer model Cusack, James C., Jr.; Liu, Rong; Xia, Lijun; Chao, Ta-Hsiang; Pien, Christine; Niu, Wei; Palombella, Vito J.; Neuteboom, Saskia T. C.; Palladino, Michael A. Share Save
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Intratumoral spread and increased efficacy of a p53-VP22 fusion protein expressed by a recombinant adenovirus Wills, KN; Atencio, IA; Avanzini, JB; Neuteboom, S; Phelan, A; Philopena, J; Sutjipto, S; Vaillancourt, MT; Wen, VF; Ralston, RO; Johnson, DE Share Save
Enhanced apoptotic activity of a p53 variant in tumors resistant to wild-type p53 treatment Atencio, IA; Avanzini, JB; Johnson, D; Neuteboom, S; Vaillancourt, MT; Nielsen, LL; Hajian, G; Sutjipto, S; Sugarman, BJ; Philopena, J; McAllister, DL; Beltran, JC; Nodelman, M; Ramachandra, M; Wills, KN Share Save
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