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Identifying therapeutic targets in low-grade serous ovarian carcinomas with no specific molecular profile Pishas, Kathleen, I; Cowley, Karla J.; Marinovic, Evanny; Kobel, Martin; Llaurado-Fernandez, Marta; Kim, Hannah; Bao, Shaine Chenxin; Mizikovsky, Dalia; Palpant, Nathan J.; Shrestha, Raunak; Vary, Robert; Luu, Jennii; Meunier, Liliane; Semple, Timothy; Blancafort, Pilar; Golden, Emily; Cohen, Paul A.; Carey, Mark S.; Campbell, Ian G.; Simpson, Kaylene J.; Cheasley, Dane Share Save
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GGNBP2 regulates MDA5 sensing triggered by self double-stranded RNA following loss of ADAR1 editing Heraud-Farlow, Jacki E.; Taylor, Scott R.; Chalk, Alistair M.; Escudero, Adriana; Hu, Shi-Bin; Goradia, Ankita; Sun, Tao; Li, Qin; Nikolic, Iva; Li, Jin Billy; Fidalgo, Miguel; Guallar, Diana; Simpson, Kaylene J.; Walkley, Carl R. Share Save
CDK9 inhibition constrains multiple oncogenic transcriptional and epigenetic pathways in prostate cancer (vol 131, pg 1092, 2024) Rahman, Razia; Rahaman, Muhammed H.; Hanson, Adrienne R.; Choo, Nicholas; Xie, Jianling; Townley, Scott L.; Shrestha, Raj; Hassankhani, Ramin; Islam, Saiful; Ramm, Susanne; Simpson, Kaylene J.; Risbridger, Gail P.; Best, Giles; Centenera, Margaret M.; Balk, Steven P.; Kichenadasse, Ganessan; Taylor, Renea A.; Butler, Lisa M.; Tilley, Wayne D.; Conn, Simon J.; Lawrence, Mitchell G.; Wang, Shudong; Selth, Luke A. Share Save
RNA kinetics influence the response to transcriptional perturbation in leukaemia cell lines Todorovski, Izabela; Tsang, Mary-Jane; Feran, Breon; Fan, Zheng; Gadipally, Sreeja; Yoannidis, David; Kong, Isabella Y.; Bjelosevic, Stefan; Rivera, Sarahi; Voulgaris, Olivia; Zethoven, Magnus; Hawkins, Edwin D.; Simpson, Kaylene J.; Arnau, Gisela Mir; Papenfuss, Anthony T.; Johnstone, Ricky W.; Vervoort, Stephin J. Share Save
A new method for network bioinformatics identifies novel drug targets for mucinous ovarian carcinoma Craig, Olivia; Lee, Samuel; Pilcher, Courtney; Saoud, Rita; Abdirahman, Suad; Salazar, Carolina; Williams, Nathan; Ascher, David B.; Vary, Robert; Luu, Jennii; Cowley, Karla J.; Ramm, Susanne; Li, Mark Xiang; Thio, Niko; Li, Jason; Semple, Tim; Simpson, Kaylene J.; Gorringe, Kylie L.; Holien, Jessica K. Share Save
CDK9 inhibition inhibits multiple oncogenic transcriptional and epigenetic pathways in prostate cancer Rahman, Razia; Rahaman, Muhammed H.; Hanson, Adrienne R.; Choo, Nicholas; Xie, Jianling; Townley, Scott L.; Shrestha, Raj; Hassankhani, Ramin; Islam, Saiful; Ramm, Susanne; Simpson, Kaylene J.; Risbridger, Gail P.; Best, Giles; Centenera, Margaret M.; Balk, Steven P.; Kichenadasse, Ganessan; Taylor, Renea A.; Butler, Lisa M.; Tilley, Wayne D.; Conn, Simon J.; Lawrence, Mitchell G.; Wang, Shudong; Selth, Luke A. Share Save
Delineating functional drivers of esophageal adenocarcinoma to identify synthetic lethal interactions Milne, Julia V.; Mustafa, Ebtihal; Fujihara, Kenji; Kusnadi, Eric; Trigos, Anna; Thio, Niko; Pechlivanis, Maree; Cabalag, Carlos; Gulati, Twishi; Simpson, Kaylene; Duong, Cuong; Furic, Luc; Phillips, Wayne; Clemons, Nicholas Share Save
CX-5461 sensitizes DNA damage repair-proficient castrate-resistant prostate cancer to PARP inhibition Lawrence, Mitchell G.; Porter, Laura H.; Choo, Nicholas; Sanij, Elaine; Taylor, Renea; Pearson, Richard; Simpson, Kaylene J.; Hannan, Ross D.; Sandhu, Shahneen; Furic, Luc Share Save
Delineating functional drivers of esophageal adenocarcinoma to identify synthetic lethal interactions Milne, Julia V.; Mustafa, Ebtihal; Fujihara, Kenji; Kusnadi, Eric; Trigos, Anna; Thio, Niko; Pechlivanis, Maree; Cabalag, Carlos; Gulati, Twishi; Simpson, Kaylene; Duong, Cuong; Furic, Luc; Phillips, Wayne; Clemons, Nicholas Share Save
miR-99b-5p, miR-380-3p, and miR-485-3p are novel chemosensitizing miRNAs in high-risk neuroblastoma (vol 30, pg 1119, 2022) Holliday, Holly; Yang, Jessica; Dodson, Eoin; Nikolic, Iva; Kamili, Alvin; Wheatley, Madeleine; Deng, Niantao; Alexandrou, Sarah; Davis, Thomas P.; Kavallaris, Maria; Caldon, C. Elizabeth; Mccarroll, Joshua; De Preter, Katleen; Mestdagh, Pieter; Marshall, Glenn M.; Simpson, Kaylene J.; Fletcher, Jamie; Swarbrick, Alexander Share Save
Co-targeting BET, CBP, and p300 inhibits neuroendocrine signalling in androgen receptor-null prostate cancer Choo, Nicholas; Keerthikumar, Shivakumar; Ramm, Susanne; Ashikari, Daisaku; Teng, Linda; Niranjan, Birunthi; Hedwards, Shelley; Porter, Laura H.; Goode, David L.; Simpson, Kaylene J.; Taylor, Renea A.; Risbridger, Gail P.; Lawrence, Mitchell G. Share Save
Hit-to-lead optimization of 2-aminoquinazolines as anti-microbial agents against Leishmania donovani Das, Nirmal; Roy, Jayasree; Patra, Binita; Saunders, Eleanor; Sarkar, Dipika; Goon, Sunny; Sinha, Bishnu Prasad; Roy, Shreya; Roy, Swarnali; Sarif, Jafar; Bandopadhyay, Purbita; Barik, Subhasis; Mukherjee, Suravi; Mcnamara, Nicole; Varghese, Swapna; Simpson, Kaylene; Baell, Jonathan; Mcconville, Malcolm; Ganguly, Dipyaman; Talukdar, Arindam Share Save
Multi-omics approach reveals a SMAD4-deficiency signature, translational reprogramming and synthetic lethality in esophageal adenocarcinom Milne, Julia V.; Fujihara, Kenji; Kusnadi, Eric; Pechlivanis, Maree; Thio, Niko; Cabalag, Carlos; Gulati, Twishi; Gotovac, Jovana; Simpson, Kaylene; Duong, Cuong; Furic, Luc; Phillips, Wayne; Clemons, Nicholas Share Save
Quantitative subcellular reconstruction reveals a lipid mediated inter-organelle biogenesis network Lee, Richard G.; Rudler, Danielle L.; Raven, Samuel A.; Peng, Liuyu; Chopin, Anaelle; Moh, Edward S. X.; Mccubbin, Tim; Siira, Stefan J.; Fagan, Samuel V.; Debono, Nicholas J.; Stentenbach, Maike; Browne, Jasmin; Rackham, Filip F.; Li, Ji; Simpson, Kaylene J.; Marcellin, Esteban; Packer, Nicolle H.; Reid, Gavin E.; Padman, Benjamin S.; Rackham, Oliver; Filipovska, Aleksandra Share Save
Loss of SMAD4 unleashes mTOR and increases dependency on cap-dependent translation in esophageal tumorigenesis Milne, Julia V.; Mustafa, Ebtihal; Fujihara, Kenji; Kusnadi, Eric; Thio, Niko; Pechlivanis, Maree; Cabalag, Carlos; Gulati, Twishi; Simpson, Kaylene; Duong, Cuong; Furic, Luc; Phillips, Wayne; Clemons, Nicholas J. Share Save
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