Andrew W. Munro - Publications, H-index & Citations

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Andrew W. Munro

University of Manchester

61H-index

303Paper Count

1.2WCitation Count

Published Papers 126

Publication Date

The Mycobacterium tuberculosis Rv0132c Gene Product Mtb-FGD2 Can Act as an F420-Dependent Glucose Dehydrogenase

PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

IF2.8

2026-04-01

OAAI

Aderemi, Adewale V.; Snee, Matthew; Tunnicliffe, Richard B.; Johanissen, Linus O.; Cliff, Matthew J.; Levy, Colin W.; Heyes, Derren J.; Golovanova, Marina; Jowitt, Thomas A.; Hay, Sam; Munro, Andrew W.; Waltho, Jonathan P.; Leys, David

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Fragment-Based Development of Small Molecule Inhibitors Targeting Mycobacterium tuberculosis Cholesterol Metabolism

Journal of Medicinal Chemistry

IF6.8

2025-07-14

OAAI

Madeline E. Kavanagh; Kirsty J. McLean; Sophie H. Gilbert; Cecilia N. Amadi; Matthew Snee; Richard B. Tunnicliffe; Kriti Arora; Helena I. M. Boshoff; Alexander Fanourakis; Maria Jose Rebollo-Lopez; Fatima Ortega; Colin W. Levy; Andrew W. Munro; David Leys; Chris Abell; Anthony G. Coyne

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Structure Based Discovery of Inhibitors of CYP125 and CYP142 from Mycobacterium tuberculosis

CHEMISTRY-A EUROPEAN JOURNAL

IF3.7

2023-04-12

OAAI

Katariya, Mona M.; Snee, Matthew; Tunnicliffe, Richard B.; Kavanagh, Madeline E.; Boshoff, Helena I. M.; Amadi, Cecilia N.; Levy, Colin W.; Munro, Andrew W.; Abell, Chris; Leys, David; Coyne, Anthony G.; McLean, Kirsty J.

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Computation-Aided Engineering of Cytochrome P450 for the Production of Pravastatin

ACS CATALYSIS

IF13.1

2022-11-28

OAAI

Ashworth, Mark A.; Bombino, Elvira; de Jong, Rene M.; Wijma, Hein J.; Janssen, Dick B.; McLean, Kirsty J.; Munro, Andrew W.

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A new strategy for hit generation: Novel in cellulo active inhibitors of CYP121A1 from Mycobacterium tuberculosis via a combined X-ray crystallographic and phenotypic screening approach (XP screen)

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2022-02-01

OAAI

Frederickson, Martyn; Selvam, Irwin R.; Evangelopoulos, Dimitrios; McLean, Kirsty J.; Katariya, Mona M.; Tunnicliffe, Richard B.; Campbell, Bethany; Kavanagh, Madeline E.; Charoensutthivarakul, Sitthivut; Blankley, Richard T.; Levy, Colin W.; de Carvalho, Luiz Pedro S.; Leys, David; Munro, Andrew W.; Coyne, Anthony G.; Abell, Chris

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Catalytic Mechanism of Aromatic Nitration by Cytochrome P450 TxtE: Involvement of a Ferric-Peroxynitrite Intermediate

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2020-08-19

OAAI

Louka, Savvas; Barry, Sarah M.; Heyes, Derren J.; Mubarak, M. Qadri E.; Ali, Hafiz Saqib; Alkhalaf, Lona M.; Munro, Andrew W.; Scrutton, Nigel S.; Challis, Gregory L.; de Visser, Sam P.

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Characterization of the structure and interactions of P450 BM3 using hybrid mass spectrometry approaches

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2020-05-01

OAAI

Jeffreys, Laura N.; Pacholarz, Kamila J.; Johannissen, Linus O.; Girvan, Hazel M.; Barran, Perdita E.; Voice, Michael W.; Munro, Andrew W.

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Clobetasol Propionate Is a Heme-Mediated Selective Inhibitor of Human Cytochrome P450 3A5

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2020-01-22

OAAI

Wright, William C.; Chenge, Jude; Wang, Jingheng; Girvan, Hazel M.; Yang, Lei; Chai, Sergio C.; Huber, Andrew D.; Wu, Jing; Oladimeji, Peter O.; Munro, Andrew W.; Chen, Taosheng

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Structure-Activity Relationships of cyclo(L-Tyrosyl-L-tyrosine) Derivatives Binding to Mycobacterium tuberculosis CYP121: Iodinated Analogues Promote Shift to High-Spin Adduct

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2019-10-16

PREAI

Rajput, Sunnia; McLean, Kirsty J.; Poddar, Harshwardhan; Selvam, Irwin R.; Nagalingam, Gayathri; Triccas, James A.; Levy, Colin W.; Munro, Andrew W.; Hutton, Craig A.

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MhuD from Mycobacterium tuberculosis: Probing a Dual Role in Heme Storage and Degradation

ACS INFECTIOUS DISEASES

IF3.8

2019-09-03

OAAI

Matthews, Sarah; Pacholarz, Kamila J.; France, Aidan P.; Jowitt, Thomas A.; Hay, Sam; Barran, Perdita; Munro, Andrew W.

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Synthesis and biological evaluation of novel cYY analogues targeting Mycobacterium tuberculosis CYP121A1

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2019-04-01

OAAI

Kishk, Safaa M.; McLean, Kirsty J.; Sood, Sakshi; Helal, Mohamed A.; Gomaa, Mohamed S.; Salama, Ismail; Mostafa, Samia M.; de Carvalho, Luiz Pedro S.; Munro, Andrew W.; Simons, Claire

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Novel insights into P450 BM3 interactions with FDA-approved antifungal azole drugs

SCIENTIFIC REPORTS

IF3.9

2019-02-07

OAAI

Jeffreys, Laura N.; Poddar, Harshwardhan; Golovanova, Marina; Levy, Colin W.; Girvan, Hazel M.; McLean, Kirsty J.; Voice, Michael W.; Leys, David; Munro, Andrew W.

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Cytochrome P450 1A1 opens up to new substrates

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2018-12-01

OAAI

Munro, Andrew W.

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Structural and catalytic properties of the peroxygenase P450 enzyme CYP152K6 from Bacillus methanolicus

JOURNAL OF INORGANIC BIOCHEMISTRY

IF3.2

2018-11-01

OAAI

Girvan, Hazel M.; Poddar, Harshwardhan; McLean, Kirsty J.; Nelson, David R.; Hollywood, Katherine A.; Levy, Colin W.; Leys, David; Munro, Andrew W.

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P450-Catalyzed Regio- and Diastereoselective Steroid Hydroxylation: Efficient Directed Evolution Enabled by Mutability Landscaping

ACS CATALYSIS

IF13.1

2018-03-08

126

OAAI

Acevedo-Rocha, Carlos G.; Gamble, Charles G.; Lonsdale, Richard; Li, Aitao; Nett, Nathalie; Hoebenreich, Sabrina; Lingnau, Julia B.; Wirtz, Cornelia; Fares, Christophe; Hinrichs, Heike; Deege, Alfred; Mulholland, Adrian J.; Nov, Yuval; Leys, David; McLean, Kirsty J.; Munro, Andrew W.; Reetz, Manfred T.

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Structure and function of the cytochrome P450 peroxygenase enzymes

BIOCHEMICAL SOCIETY TRANSACTIONS

IF4.3

2018-02-06

180

OAAI

Munro, Andrew W.; McLean, Kirsty J.; Grant, Job L.; Makris, Thomas M.

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Design, synthesis and evaluation against Mycobacterium tuberculosis of azole piperazine derivatives as dicyclotyrosine (cYY) mimics

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2018-01-01

OAAI

Abd El-Wahab, Hend A. A.; Accietto, Mauro; Marino, Leonardo B.; McLean, Kirsty J.; Levy, Colin W.; Abdel-Rahman, Hamdy M.; El-Gendy, Mahmoud A.; Munro, Andrew W.; Aboraia, Ahmed S.; Simons, Claire

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Novel Aryl Substituted Pyrazoles as Small Molecule Inhibitors of Cytochrome P450 CYP121A1: Synthesis and Antimycobacterial Evaluation

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2017-12-07

OAAI

Taban, Ismail M.; Elshihawy, Hosam E. A. E.; Torun, Beyza; Zucchini, Benedetta; Williamson, Clare J.; Altuwairigi, Dania; Ngu, Adeline S. T.; McLean, Kirsty J.; Leyy, Colin W.; Sood, Sakshi; Marino, Leonardo B.; Munro, Andrew W.; de Caryalho, Luiz Pedro S.; Simone, Claire

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Effect of DMSO on Protein Structure and Interactions Assessed by Collision-Induced Dissociation and Unfolding

ANALYTICAL CHEMISTRY

IF6.7

2017-08-25

OAAI

Chan, Daniel S. -H.; Kavanagh, Madeline E.; McLean, Kirsty J.; Munro, Andrew. W.; Matak-Vinkovic, Dijana; Coyne, Anthony G.; Abell, Chris

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Expression, Purification, and Biochemical Characterization of the Flavocytochrome P450 CYP505A30 from Myceliophthora thermophila

ACS OMEGA

IF4.3

2017-08-18

OAAI

Baker, George J.; Girvan, Hazel M.; Matthews, Sarah; McLean, Kirsty J.; Golovanova, Marina; Waltham, Timothy N.; Rigby, Stephen E. J.; Nelson, David R.; Blankley, Richard T.; Munro, Andrew W.

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Research Directions