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Combined inhibition of MTAP and MAT2a mimics synthetic lethality in tumor models via PRMT5 inhibition Bedard, Gabriel T.; Gilaj, Nord; Peregrina, Karina; Brew, Isabella; Tosti, Elena; Shaffer, Karl; Tyler, Peter C.; Edelmann, Winfried; Augenlicht, Leonard H.; Schramm, Vern L. Share Save
Phosphoinositide and redox dysregulation by the anticancer methylthioadenosine phosphorylase transition state inhibitor Salita, Timothy; Rustam, Yepy H.; Hofferek, Vinzenz; Jackson, Michael; Tollestrup, Isaac; Sheridan, Jeffrey P.; Schramm, Vern L.; Evans, Gary B.; Reid, Gavin E.; Munkacsi, Andrew B. Share Save
MAT Gain of Activity Mutation in Helicobacter pylori Is Associated with Resistance to MTAN Transition State Analogues Feng, Mu; Namanja-Magliano, Hilda; Rajagopalan, Saranathan; Mishra, Tanmay; Ducati, Rodrigo G.; Hirsch, Brett M.; Kelly, Libusha; Szymczak, Wendy; Fajardo, Jorge Eduardo; Sidoli, Simone; Fiser, Andras; Jacobs, William R.; Schramm, Vern L. Share Save
Inhibition and Mechanism of Plasmodium falciparum Hypoxanthine-Guanine-Xanthine Phosphoribosyltransferase Minnow, Yacoba V. T.; Suthagar, Kajitha; Clinch, Keith; Ducati, Rodrigo G.; Ghosh, Agnidipta; Buckler, Joshua N.; Harijan, Rajesh K.; Cahill, Sean M.; Tyler, Peter C.; Schramm, Vern L. Share Save
The design of protozoan phosphoribosyltransferase inhibitors containing non-charged phosphate mimic residues Gai, Sinan; Suthagar, Kajitha; Shaffer, Karl J.; Jiao, Wanting; Minnow, Yacoba V. T.; Glockzin, Kayla; Maatouk, Sean W.; Katzfuss, Ardala; Meek, Thomas D.; Schramm, Vern L.; Tyler, Peter C. Share Save
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Synthesis and Characterization of Transition-State Analogue Inhibitors against Human DNA Methyltransferase 1 Lamiable-Oulaidi, Farah; Harijan, Rajesh K.; Shaffer, Karl J.; Crump, Douglas R.; Sun, Yan; Du, Quan; Gulab, Shivali A.; Khan, Ashna A.; Luxenburger, Andreas; Woolhouse, Anthony D.; Sidoli, Simone; Tyler, Peter C.; Schramm, Vern L. Share Save
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