Not logged in Structural and mechanistic bases for resistance of the M66I capsid variant to lenacapavir Briganti, Lorenzo; Annamalai, Arun S.; Bester, Stephanie M.; Wei, Guochao; Andino-Moncada, Jonathan R.; Singh, Satya P.; Kleinpeter, Alex B.; Tripathi, Meghna; Nguyen, Binh; Radhakrishnan, Rajalingam; Singh, Parmit K.; Greenwood, Juliet; Schope, Lauren I.; Haney, Reed; Huang, Szu-Wei; Freed, Eric O.; Engelman, Alan N.; Francis, Ashwanth C.; Kvaratskhelia, Mamuka Share Save
The primary mechanism for highly potent inhibition of HIV-1 maturation by lenacapavir Huang, Szu-Wei; Briganti, Lorenzo; Annamalai, Arun S.; Greenwood, Juliet; Shkriabai, Nikoloz; Haney, Reed; Armstrong, Michael L.; Wempe, Michael F.; Singh, Satya Prakash; Francis, Ashwanth C.; Engelman, Alan N.; Kvaratskhelia, Mamuka Share Save
Elasticity of the HIV-1 core facilitates nuclear entry and infection Deshpande, Akshay; Bryer, Alexander J.; Andino-Moncada, Jonathan R.; Shi, Jiong; Hong, Jun; Torres, Cameron; Harel, Shimon; Francis, Ashwanth C.; Perilla, Juan R.; Aiken, Christopher; Rousso, Itay Share Save
HIV-1 usurps mixed-charge domain-dependent CPSF6 phase separation for higher-order capsid binding, nuclear entry and viral DNA integration Jang, Sooin; Bedwell, Gregory J.; Singh, Satya P.; Yu, Hyun Jae; Arnarson, Bjarki; Singh, Parmit K.; Radhakrishnan, Rajalingam; Douglas, AidanDarian W.; Ingram, Zachary M.; Freniere, Christian; Akkermans, Onno; Sarafianos, Stefan G.; Ambrose, Zandrea; Xiong, Yong; Anekal, Praju, V; Montero Llopis, Paula; Kewalramani, Vineet N.; Francis, Ashwanth C.; Engelman, Alan N. Share Save
Multidisciplinary studies with mutated HIV-1 capsid proteins reveal structural mechanisms of lattice stabilization Gres, Anna T.; Kirby, Karen A.; Mcfadden, William M.; Du, Haijuan; Liu, Dandan; Xu, Chaoyi; Bryer, Alexander J.; Perilla, Juan R.; Shi, Jiong; Aiken, Christopher; Fu, Xiaofeng; Zhang, Peijun; Francis, Ashwanth C.; Melikyan, Gregory B.; Sarafianos, Stefan G. Share Save
Prion-like low complexity regions enable avid virus-host interactions during HIV-1 infection Wei, Guochao; Iqbal, Naseer; Courouble, Valentine V.; Francis, Ashwanth C.; Singh, Parmit K.; Hudait, Arpa; Annamalai, Arun S.; Bester, Stephanie; Huang, Szu-Wei; Shkriabai, Nikoloz; Briganti, Lorenzo; Haney, Reed; KewalRamani, Vineet N.; Voth, Gregory A.; Engelman, Alan N.; Melikyan, Gregory B.; Griffin, Patrick R.; Asturias, Francisco; Kvaratskhelia, Mamuka Share Save
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HIV-1 replication complexes accumulate in nuclear speckles and integrate into speckle-associated genomic domains (vol 11, pg 3505, 2020) Francis, Ashwanth C.; Marin, Mariana; Singh, Parmit K.; Achuthan, Vasudevan; Prellberg, Mathew J.; Palermino-Rowland, Kristina; Lan, Shuiyun; Tedbury, Philip R.; Sarafianos, Stefan G.; Engelman, Alan N.; Melikyan, Gregory B. Share Save
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HIV-1 replication complexes accumulate in nuclear speckles and integrate into speckle-associated genomic domains Francis, Ashwanth C.; Marin, Mariana; Singh, Parmit K.; Achuthan, Vasudevan; Prellberg, Mathew J.; Palermino-Rowland, Kristina; Lan, Shuiyun; Tedbury, Philip R.; Sarafianos, Stefan G.; Engelman, Alan N.; Melikyan, Gregory B. Share Save
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A Novel Phenotype Links HIV-1 Capsid Stability to cGAS-Mediated DNA Sensing Siddiqui, Mohammad Adnan; Saito, Akatsuki; Halambage, Upul D.; Ferhadian, Damien; Fischer, Douglas K.; Francis, Ashwanth C.; Melikyan, Gregory B.; Ambrose, Zandrea; Aiken, Christopher; Yamashita, Masahiro Share Save
HIV-1 integrase tetramers are the antiviral target of pyridine-based allosteric integrase inhibitors Koneru, Pratibha C.; Francis, Ashwanth C.; Deng, Nanjie; Rebensburg, Stephanie V.; Hoyte, Ashley C.; Lindenberger, Jared; Adu-Ampratwum, Daniel; Larue, Ross C.; Wempe, Michael F.; Engelman, Alan N.; Lyumkis, Dmitry; Fuchs, James R.; Levy, Ronald M.; Melikyan, Gregory B.; Kvaratskhelia, Mamuka Share Save
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