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J

Jana Sopková‐de Oliveira Santos

cermn ur4258

28H-index
222Paper Count
2.7KCitation Count
Published Papers 64
Publication Date
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Integrative in silico and experimental identification of non-covalent UBE2N inhibitors enhancing PARP inhibitor sensitivity
errEuropean Journal of Medicinal Chemistry Reports
IF4.1
err2026-07-30
err0
errOAAI
errCôme Ghadi; Shafi Ullah Khan; Léonie Ibazizene; Florian Schwalen; Charline Kieffer; Peggy Suzanne; Julie Jaouen; Hassiba Bouafia; Xavier Thuru; Marie Cornu; Cedric Lecoutey; Matthieu Meryet-Figuiere; Anne Sophie Voisin-Chiret; Louis-Bastien Weiswald; Jana Sopkova-de Oliveira Santos
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Rational Design and Evaluation of Rivastigmine-Based Pleiotropic Prodrugs for the Treatment of Alzheimer’s Disease
errACS Chemical Neuroscience
IF3.9
err2026-04-13
err0
PREAI
errValentin Travers-Lesage; Marc Since; Alice Wang; Audrey Davis; Dimitri Fayolle; Benoit Bernay; Fabrice Modeste; Florian Nachon; Xavier Brazzalotto; Lucie Crouzier; Jana Sopkova-De Oliveira Santos; Tangui Maurice; Patrick Dallemagne; Christophe Rochais
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ID Card of Mcl-1 PROTAC degrader: From in silico design to biological validation in chemoresistant ovarian cancer
errEuropean Journal of Medicinal Chemistry Reports
IF4.1
err2026-04-03
err0
errOAAI
errMarie Cornu; Jocelyn Pezeril; Nicolas Guedeney; Hippolyte Paysant; Thomas Lemaitre; Florian Schwalen; Romane Florent; Julie N’Guyen; Sophie Corvaisier; Marc Since; Dimitri Fayolle; Amina Hamza; Mike Maillasson; Jana Sopkova-de Oliveira Santos; Charline Kieffer; Laurent Poulain; Anne Sophie Voisin-Chiret
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UBE2N: Hope on the Cancer Front, How to Inhibit This Promising Target Prospect?
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2025-01-14
err0
PREAI
errSchwalen, Florian; Ghadi, Come; Ibazizene, Leonie; Khan, Shafi Ullah; Santos, Jana Sopkova-de Oliveira; Weiswald, Louis-Bastien; Voisin-Chiret, Anne Sophie; Meryet-Figuiere, Matthieu; Kieffer, Charline
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Synthesis, in vitro and in vivo biological evaluation of novel dual compounds targeting both acetylcholinesterase and serotonergic 5-HT4 receptors with potential interest in the treatment of Alzheimer's disease
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2024-12-01
err0
errOAAI
errRochais, Christophe; Lecoutey, Cedric; Lalut, Julien; Davis, Audrey; Duval, Emilie; Gaven, Florence; Largilliere, Stacy; Nee, Gerald; Corvaisier, Sophie; Santos, Jana Sopkova de Oliveira; Since, Marc; Freret, Thomas; Legrand, Romain; Callizot, Noelle; Claeysen, Sylvie; Boulouard, Michel; Dallemagne, Patrick
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Towards New Anti-Inflammatory Agents: Design, Synthesis and Evaluation of Molecules Targeting XIAP-BIR2
errCHEMMEDCHEM
IF3.4
err2024-11-12
err0
PREAI
errFarag, Marc; Guedeney, Nicolas; Schwalen, Florian; Zadoroznyj, Aymeric; Barczyk, Amelie; Giret, Martin; Antraygues, Kevin; Wang, Alice; Cornu, Marie; Suzanne, Peggy; Since, Marc; Voisin-Chiret, Anne Sophie; Dubrez, Laurence; Leleu-Chavain, Natascha; Kieffer, Charline; Santos, Jana Sopkova-de Oliveira
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Disruption of PHF6 Peptide Aggregation from Tau Protein: Mechanisms of Palmatine Chloride in Preventing Early PHF6 Aggregation
errACS CHEMICAL NEUROSCIENCE
IF3.9
err2024-10-15
err0
PREAI
errFagnen, Charline; Giovannini, Johanna; Vignol, Thomas; Since, Marc; Catto, Marco; Voisin-Chiret, Anne Sophie; Santos, Jana Sopkova-de Oliveira
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Design, synthesis and preliminary biological evaluation of rivastigmine-INDY hybrids as multitarget ligands against Alzheimer's disease by targeting butyrylcholinesterase and DYRK1A/CLK1 kinases
errRSC MEDICINAL CHEMISTRY
IF3.6
err2024-01-01
err0
errOAAI
errTintas, Mihaela-Liliana; Peauger, Ludovic; Barre, Anais; Papamicael, Cyril; Besson, Thierry; Sopkova-de Oliveira Santos, Jana; Gembus, Vincent; Levacher, Vincent
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Gold(I)-Mediated Radioiododecarboxylation of Arenes
errORGANIC LETTERS
IF5
err2023-11-07
err2
PREAI
errBloux, Hugo; Khouya, Ahmed Ait; Sopkova-de Oliveira Santos, Jana; Fabis, Frederic; Dubost, Emmanuelle; Cailly, Thomas
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Computational Tool to Design Small Synthetic Inhibitors Selective for XIAP-BIR3 Domain
errMOLECULES
IF4.6
err2023-06-30
err1
errOAAI
errFarag, Marc; Kieffer, Charline; Guedeney, Nicolas; Voisin-Chiret, Anne Sophie; Sopkova-de Oliveira Santos, Jana
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Discovery of Bis-Imidazoline Derivatives as New CXCR4 Ligands
errMOLECULES
IF4.6
err2023-01-24
err4
errOAAI
errZhou, Zhicheng; Staropoli, Isabelle; Brelot, Anne; Suzanne, Peggy; Lesnard, Aurelien; Fontaine, Fanny; Perato, Serge; Rault, Sylvain; Helynck, Olivier; Arenzana-Seisdedos, Fernando; Santos, Jana Sopkova-de Oliveira; Lagane, Bernard; Munier-Lehmann, Helene; Colin, Philippe
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Straightforward Access to a New Class of Dual DYRK1A/CLK1 Inhibitors Possessing a Simple Dihydroquinoline Core
errMOLECULES
IF4.6
err2022-12-21
err0
errOAAI
errTintas, Mihaela-Liliana; Peauger, Ludovic; Alix, Florent; Papamicael, Cyril; Besson, Thierry; Santos, Jana Sopkova-de Oliveira; Gembus, Vincent; Levacher, Vincent
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Synthesis and Physicochemical Properties of Cryptophazane-A Soluble and Functionalizable C1-Symmetrical Cryptophane
errANGEWANDTE CHEMIE-INTERNATIONAL EDITION
IF16.9
err2022-10-17
err4
PREAI
errVigier, Clement; Fayolle, Dimitri; El Siblani, Hussein; Santos, Jana Sopkova-de Oliveira; Fabis, Frederic; Cailly, Thomas; Dubost, Emmanuelle
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On the Tracks of the Aggregation Mechanism of the PHF6 Peptide from Tau Protein: Molecular Dynamics, Energy, and Interaction Network Investigations
errACS CHEMICAL NEUROSCIENCE
IF3.9
err2022-09-26
err5
PREAI
errFagnen, Charline; Giovannini, Johanna; Catto, Marco; Voisin-Chiret, Anne Sophie; Santos, Jana Sopkova-de Oliveira
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Tau protein aggregation: Key features to improve drug discovery screening
errDRUG DISCOVERY TODAY
IF7.5
err2022-05-01
err20
errOAAI
errGiovannini, Johanna; Smeralda, Willy; Jouanne, Marie; Santos, Jana Sopkova-de Oliveira; Catto, Marco; Voisin-Chiret, Anne Sophie
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Cryptic Pockets Repository through Pocket Dynamics Tracking and Metadynamics on Essential Dynamics Space: Applications to Mcl-1
errJOURNAL OF CHEMICAL INFORMATION AND MODELING
IF5.3
err2021-11-08
err4
PREAI
errBenabderrahmane, Mohammed; Bureau, Ronan; Voisin-Chiret, Anne Sophie; Santos, Jana Sopkova-de Oliveira
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Development of Novel Potential Pleiotropic Compounds of Interest in Alzheimer's Disease Treatment through Rigidification Strategy
errMOLECULES
IF4.6
err2021-04-26
err5
errOAAI
errLecoutey, Cedric; Legay, Remi; Davis, Audrey; Sopkova-de Oliveira Santos, Jana; Dallemagne, Patrick; Rochais, Christophe
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Pleiotropic prodrugs: Design of a dual butyrylcholinesterase inhibitor and 5-HT6 receptor antagonist with therapeutic interest in Alzheimer's disease
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2021-01-01
err25
errOAAI
errToublet, Francois-Xavier; Lalut, Julien; Hatat, Berenice; Lecoutey, Cedric; Davis, Audrey; Since, Marc; Corvaisier, Sophie; Freret, Thomas; Santos, Jana Sopkova-de Oliveira; Claeysen, Sylvie; Boulouard, Michel; Dallemagne, Patrick; Rochais, Christophe
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First Synthesis of Racemic Trans Propargylamino-Donepezil, a Pleiotrope Agent Able to Both Inhibit AChE and MAO-B, with Potential Interest against Alzheimer's Disease
errMOLECULES
IF4.6
err2020-12-27
err17
errOAAI
errGuieu, Benjamin; Lecoutey, Cedric; Legay, Remi; Davis, Audrey; Sopkova de Oliveira Santos, Jana; Altomare, Cosimo Damiano; Catto, Marco; Rochais, Christophe; Dallemagne, Patrick
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Insights into Mcl-1 Conformational States and Allosteric Inhibition Mechanism from Molecular Dynamics Simulations, Enhanced Sampling, and Pocket Crosstalk Analysis
errJOURNAL OF CHEMICAL INFORMATION AND MODELING
IF5.3
err2020-05-11
err9
PREAI
errBenabderrahmane, Mohammed; Bureau, Ronan; Voisin-Chiret, Anne Sophie; Santos, Jana Sopkova-de Oliveira
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Research Directions

No research directions
Co-authors
Cooperation Journals
L
Laurent Meijer
H-index: 93 · Papers: 541
C
Carmen Garrido
H-index: 84 · Papers: 490
T
Timothy Clark
H-index: 78 · Papers: 887
H
Hubert Vaudry
H-index: 76 · Papers: 993
D
Denis Vivien
H-index: 73 · Papers: 530
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