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SaveShare Save Discovery of 1,2-diaryl-3-oxopyrazolidin-4-carboxamides as a new class of MurA enzyme inhibitors and characterization of their antibacterial activity
Wagdy, Reem A.; Abutaleb, Nader S.; Fathalla, Reem K.; Elgammal, Yehia; Weck, Stefanie; Pal, Rusha; Fischer, Patrick D.; Ducho, Christian; Abadi, Ashraf H.; Seleem, Mohamed N.; Engel, Matthias; Abdel-Halim, Mohammad Share Save Inhibitors of the Elastase LasB for the Treatment of Pseudomonas aeruginosa Lung InfectionsKonstantinovic, Jelena; Kany, Andreas M.; Alhayek, Alaa; Abdelsamie, Ahmed S.; Sikandar, Asfandyar; Voos, Katrin; Yao, Yiwen; Andreas, Anastasia; Shafiei, Roya; Loretz, Brigitta; Schoenauer, Esther; Bals, Robert; Brandstetter, Hans; Hartmann, Rolf W.; Ducho, Christian; Lehr, Claus-Michael; Beisswenger, Christoph; Mueller, Rolf; Rox, Katharina; Haupenthal, Joerg; Hirsch, Anna K. H. Share Save Discovery, Synthesis, and Optimization of 1,2,4-Triazolyl Pyridines Targeting Mycobacterium tuberculosisBerida, Tomayo; Mckee, Samuel R.; Chatterjee, Shamba; Manning, Destinee L.; Li, Wei; Pandey, Pankaj; Tripathi, Siddharth Kaushal; Mreyoud, Yassin; Smirnov, Asya; Doerksen, Robert J.; Jackson, Mary; Ducho, Christian; Stallings, Christina L.; Roy, Sudeshna Share Save GreenMedChem: the challenge in the next decade toward eco-friendly compounds and processes in drug designCastiello, Carola; Junghanns, Pierre; Mergel, Annika; Jacob, Claus; Ducho, Christian; Valente, Sergio; Rotili, Dante; Fioravanti, Rossella; Zwergel, Clemens; Mai, Antonello Share Save Share Save Identification and Biochemical Characterization of Pyrrolidinediones as Novel Inhibitors of the Bacterial Enzyme MurAFathalla, Reem K.; Froehner, Wolfgang; Bader, Chantal D.; Fischer, Patrick D.; Dahlem, Charlotte; Chatterjee, Deep; Mathea, Sebastian; Kiemer, Alexandra K.; Arthanari, Haribabu; Muller, Rolf; Abdel-Halim, Mohammad; Ducho, Christian; Engel, Matthias Share Save Inhibition of Collagenase Q1 of Bacillus cereus as a Novel Antivirulence Strategy for the Treatment of Skin-Wound InfectionsAlhayek, Alaa; Khan, Essak S.; Schoenauer, Esther; Daeinghaus, Tobias; Shafiei, Roya; Voos, Katrin; Han, Mitchell K. L.; Ducho, Christian; Posselt, Gernot; Wessler, Silja; Brandstetter, Hans; Haupenthal, Joerg; del Campo, Aranzazu; Hirsch, Anna K. H. Share Save Enzymatic Cβ-H Functionalization of L-Arg and L-Leu in Nonribosomally Derived Peptidyl Natural Products: A Tale of Two OxidoreductasesCui, Zheng; Han Nguyen; Bhardwaj, Minakshi; Wang, Xiachang; Bueschleb, Martin; Lemke, Anke; Schuetz, Christian; Rohrbacher, Christian; Junghanns, Pierre; Koppermann, Stefan; Ducho, Christian; Thorson, Jon S.; Van Lanen, Steven G. Share Save A biphenyl inhibitor of eIF4E targeting an internal binding site enables the design of cell-permeable PROTAC-degradersFischer, Patrick D.; Papadopoulos, Evangelos; Dempersmier, Jon M.; Wang, Zi-Fu; Nowak, Radoslaw P.; Donovan, Katherine A.; Kalabathula, Joann; Gorgulla, Christoph; Junghanns, Pierre P. M.; Kabha, Eihab; Dimitrakakis, Nikolaos; Petrov, Ognyan, I; Mitsiades, Constantine; Ducho, Christian; Gelev, Vladimir; Fischer, Eric S.; Wagner, Gerhard; Arthanari, Haribabu Share Save Phosphonate as a Stable Zinc-Binding Group for Pathoblocker Inhibitors of Clostridial Collagenase H (ColH)Voos, Katrin; Schoenauer, Esther; Alhayek, Alaa; Haupenthal, Joerg; Andreas, Anastasia; Mueller, Rolf; Hartmann, Rolf W.; Brandstetter, Hans; Hirsch, Anna K. H.; Ducho, Christian Share Save N-Aryl mercaptoacetamides as potential multi-target inhibitors of metallo-β-lactamases (MBLs) and the virulence factor LasB from Pseudomonas aeruginosaYahiaoui, Samir; Voos, Katrin; Haupenthal, Joerg; Wichelhaus, Thomas A.; Frank, Denia; Weizel, Lilia; Rotter, Marco; Brunst, Steffen; Kramer, Jan S.; Proschak, Ewgenij; Ducho, Christian; Hirsch, Anna K. H. Share Save Share Save Share Save Pyridoxal-5′-phosphate-dependent alkyl transfer in nucleoside antibiotic biosynthesisCui, Zheng; Overbay, Jonathan; Wang, Xiachang; Liu, Xiaodong; Zhang, Yinan; Bhardwaj, Minakshi; Lemke, Anke; Wiegmann, Daniel; Niro, Giuliana; Thorson, Jon S.; Ducho, Christian; Van Lanen, Steven G. Share Save Specific, Sensitive, and Quantitative Detection of HER-2 mRNA Breast Cancer Marker by Fluorescent Light-Up Hybridization ProbesSaady, Abed; Wojtyniak, Melissa; Varon, Eli; Boettner, Verena; Kinor, Noa; Shav-Tal, Yaron; Ducho, Christian; Fischer, Bilha Share Save Share Save Share Save Share Save 
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