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Christopher J. Schofield

University of Oxford

112H-index
1.3KPaper Count
6.3WCitation Count
Published Papers 476
Publication Date
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Unanticipated intermediates during isopenicillin N synthase catalysis identified by time-resolved X-ray free-electron laser studies
errNature Catalysis
IF44.6
err2026-10-09
err0
errOAAI
errPatrick Rabe; Hiroki Makita; Rebecca Southwart; Midhun George Thomas; Mihails Kazaks; Shyam Basak; Tiankun Zhou; William K. Myers; Margaret D. Doyle; Philipp S. Simon; Shusaku Hayama; J. Frederick W. Mosselmans; Alexander T. Stead; Abraham O. Oluwole; Malkit Sami; Ian Clifton; Pierre Aller; Asmit Bhowmick; Anthony Tumber; Jos J. A. G. Kamps; Karina Calvopiña; Agata Butryn; Robert Bosman; Arjun Cheema; Jordan Welsh; James D. S. Linyard; Frederick J. H. Foster; Pauline A. Lang; Mariska de Munnik; Stephen M. Keable; Medhanjali Dasgupta; In-Sik Kim; Isabel Bogacz; Kuntal Chatterjee; Kyle D. Sutherlin; Corey J. Kaminsky; Jürgen Brem; Michael A. McDonough; Christina Redfield; James R. D. Montgomery; Coral Mycroft; Anastasya Shilova; Nicholas Devenish; Frederic P. Poitevin; Sebastian Dehe; Vandana Tiwari; Humberto Sanchez; Daniel J. Rosenberg; Mark S. Hunter; Leland B. Gee; Uwe Bergmann; Roberto Alonso-Mori; Jaehyun Park; Shigeki Owada; Kensuke Tono; Danny Axford; Robin L. Owen; Daniel W. Paley; Nicholas K. Sauter; David Mittan-Moreau; Aaron S. Brewster; Carol V. Robinson; Vittal K. Yachandra; Junko Yano; Edgars Suna; Christo Z. Christov; Allen M. Orville; Jan F. Kern; Christopher J. Schofield
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Human carbonic anhydrase II as a versatile biocatalyst for the synthesis of chiral aryl-1,2-diols
errCommunications Chemistry
IF6.2
err2026-07-28
err0
errOAAI
errLaura Edit Barabás; Diana Maria Scrob; Monica Ioana Toşa; Jürgen Brem; László Poppe; Christopher J. Schofield; Csaba Paizs
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errSave
Substrate-Selective Inhibition of the SARS-CoV-2 Papain-Like Protease: Inhibition of Hydrolysis of Human Over Viral Substrates
errChemistry – A European Journal
IF0
err2026-06-12
err0
errOAAI
errSakshi Sharma; Peter A. C. Wing; Wojtek Trede; Shyam Basak; Simeon D. Draganov; Taylah Andrews-Clark; Eidarus Salah; Petra Lukacik; Claire Strain-Damerell; Adán Pinto-Fernández; Martin A. Walsh; Fernanda Duarte; Christopher J. Schofield; Lennart Brewitz
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errSave
Beyond Histone Demethylation: Mechanisms of N-Alkyl Consecutive Oxidations by the Non-Heme Fe(II)/2-Oxoglutarate Oxygenase KDM6B
errJACS Au
IF8.7
err2026-06-06
err0
errOAAI
errSimahudeen Bathir Jaber Sathik Rifayee; Sudheesh Devadas; Midhun George Thomas; Bhargav Varada; Ethan Sommer; Cassandra Talaba; Christopher Schofield; Christo Z. Christov
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errSave
Evidence that SmTetX is not a tetracycline resistance determinant
errMicrobiology Spectrum
IF3.8
err2026-06-02
err0
PREAI
errBeech, Matthew J.; Trush, Maria M.; Toma, Edmond C.; Farley, Alistair J. M.; Walsh, Timothy R.; Schofield, Christopher J.
errShare
errSave
Development of Water-Trapping Pyrrole-2-carboxylic Acids as Broad-Spectrum Metallo-β-lactamase Inhibitors
errJournal of Medicinal Chemistry
IF6.8
err2026-05-14
err0
errOAAI
errMonisha Singha; Liam A. Wilson; Elisabete C. C. M. Moura; Maria M. Trush; Karina Calvopina; Gurleen Kaur; Greta Zaborskytė; Toms Kalniņš; Tharindi Panduwawala; Matthew J. Bowen; Matthew J. Beech; Jürgen Brem; Peter J. McHugh; Edgars Suna; Timothy R. Walsh; Christopher J. Schofield; Alistair J. M. Farley
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errSave
Structure-guided optimisation of fenofibrate-derived oxidative phosphorylation inhibitors to modify tumour hypoxia
errrsc med. chem.
IF0
err2026-04-29
err0
errOAAI
errJames P. Holt-Martyn †; Nicole Machado †; James T. T. Coates; Rathi Puliyadi; Thomas Ashton; Elysia Traynor; Samina Aslam; Thomas K. Wise; Gonzalo Rodriguez-Berriguete; Christopher J. Schofield; Geoff S. Higgins
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errSave
β-Lactam antibiotics and β-lactamases: historical perspectives and a review of β-lactamase inhibitors derived from natural products
errnat. prod. rep.
IF0
err2026-04-23
err0
errOAAI
errPhanankosi Moyo †; Ikhane O. Albert †; Neo Hlungwani; Thulani Sibanda; Perfoy Lumu; Ndivhuwo Kevin Khorommbi; Gurleen Kaur; Karina Calvopina Tapia; George Siegwart; Nana Kwaku Buabeng; Cynthia A. Danquah; Lyndy J. McGaw; Sekelwa Cosa; Christopher J. Schofield; Vinesh J. Maharaj
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errSave
KDM3A catalyses the oxidation of acetyl-lysine to hydroxyacetyl-lysine on histone H3K9
errNature Chemistry
IF20.2
err2026-04-15
err0
errOAAI
errRoman Belle; John-Paul Bukowski; Rachel Schiller; Ronald Cutler; Eidarus Salah; Robert S. Dawber; Anthony Tumber; Joanna Bonnici; Jessica D. Kindrick; Loane Serrano; Patrick Rabe; Catrine Johansson; Marie-Hélène Ruchaud; Richard J. Hopkinson; William D. Figg, Sr; Paul E. Brennan; David R. Mole; Simone Sidoli; Akane Kawamura; Christopher J. Schofield
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errSave
JmjC Histone Demethylases: Beyond Histone Lysine Demethylation
errCHIMIA
IF1.6
err2026-03-01
err1
PREAI
errBonnici, Joanna; Schofield, Christopher J.; Kawamura, Akane
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errSave
Structural basis of the promiscuity of the unusual Fe(II) and 2-oxoglutarate dependent human aspartate/asparagine-β-hydroxylase
errNature Communications
IF15.7
err2026-02-25
err0
errOAAI
errMariska de Munnik; Amelia Brasnett; Tiankun Zhou; William Myers; Yicheng Wang; Kuntal Chatterjee; Anthony Tumber; Stephen A. Marshall; Philipp S. Simon; Pierre Aller; Anastasiia Shilova; Danny Axford; Hiroki Makita; Daniel W. Paley; Vandana Tiwari; Alexander T. Stead; Sebastian Dehe; Humberto Sanchez; Daniel J. Rosenberg; Roberto Alonso-Mori; Asmit Bhowmick; Junko Yano; Vittal K. Yachandra; Jaehyun Park; Sehan Park; Allen M. Orville; Lennart Brewitz; Jan F. Kern; Christopher J. Schofield; Patrick Rabe
errShare
errSave
Expanding the Alkene-Forming Capability of the Pseudomonas Savastanoi Ethylene-Forming Enzyme
errChemCatChem
IF3.9
err2026-01-14
err0
errOAAI
errSiddhant Dhingra; Yihong Sun; Zhihong Zhang; Christopher J. Schofield; Lennart Brewitz
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errSave
In Vitro and In Vivo Evaluation of Nitroxoline as an Effective Antimicrobial Alternative to Poultry Production
errAntibiotics
IF0
err2026-01-07
err0
errOAAI
errYuqing Zhou; Maria M. Trush; Lewis Ibbotson; Laura Espina; Aditya Kumar Lankapalli; Alistair J. M. Farley; Huangwei Song; Congming Wu; Xingyuan Cao; Xi Xia; Charlotte J. Gray-Hammerton; Alice Moorey; Amelie Delaitre; George Siegwart; Shaolin Wang; Yang Wang; Jianzhong Shen; Christopher J. Schofield; Timothy R. Walsh
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errSave
Structural and functional consequences of aspartate/asparagine-β-hydroxylase variants causing Traboulsi Syndrome
errJournal of Biological Chemistry
IF3.9
err2025-12-05
err0
errOAAI
errCynthia X. Hou; Amelia Brasnett; Patrick Rabe; Christopher J. Schofield; Lennart Brewitz
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errSave
Cellular and functional insights into FIH-mediated hydroxylation of TRPA1
errJournal of Biological Chemistry
IF3.9
err2025-11-04
err0
errOAAI
errTao Guo; Dianne Marquez Lopez; Siyuan Wang; Liudi Yao; Xi Li; Elizabeth R. Davies; Mariana Vargas-Caballero; Nullin Divecha; Christopher J. Schofield; Katrin Deinhardt; Yihua Wang
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errSave
Small but powerful
errNature Reviews Chemistry
IF51.7
err2025-11-04
err0
PREAI
errAndrew V. Stachulski; Christopher J. Schofield
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errSave
Profiling Inhibitor Scaffolds for the Cancer Target Jumonji-C Domain-Containing Protein 6
errChemMedChem
IF3.4
err2025-10-31
err0
errOAAI
errThomas P. Corner; Eidarus Salah; Anthony Tumber; James P. Holt-Martyn; Lennart Brewitz; Christopher J. Schofield
errShare
errSave
C6-Alkoxy substituted penicillins are potent non-covalently binding inhibitors of the SARS-CoV-2 main protease
errRSC Med. Chem.
IF3.6
err2025-10-27
err0
errOAAI
errDorian-Gabriel Muntean; Wojtek Treyde; Linda Kinena; Eidarus Saleh; Hani Choudhry; Fernanda Duarte; Lennart Brewitz; Christopher J Schofield
errShare
errSave
Evidence human FTO catalyses hydroxylation of N6-methyladenosine without direct formation of a demethylated product contrasting with ALKBH5/2/3 and bacterial AlkB
errNucleic Acids Research
IF13.1
err2025-08-28
err0
errOAAI
errSimranjeet Kaur; Pratheesh Maheswaran; Samanpreet Kaur; Yingqi Lai; Eidarus Salah; Dong Zhang; Shifali Shishodia; Christopher J Schofield; Wei Shen Aik
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errSave
Revealing the catalytic mechanism of the Fe(II)/2-oxoglutarate-dependent human epigenetic modifying enzyme ALKBH5
errCell Reports Physical Science
IF7.3
err2025-08-12
err0
errOAAI
errFathima Hameed Cherilakkudy; Midhun George Thomas; Ann Varghese; Sodiq O. Waheed; Anandhu Krishnan; Vincenzo Venditti; Christopher J. Schofield; Deyu Li; Christo Z. Christov; Tatyana G. Karabencheva-Christova
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Research Directions

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Co-authors
Cooperation Journals
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Adrian L. Harris
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E
Eamonn R. Maher
H-index: 134 · Papers: 850
D
David I. Stuart
H-index: 129 · Papers: 1.1K
P
Peter J. Ratcliffe
H-index: 125 · Papers: 634
S
Stefan Knapp
H-index: 111 · Papers: 1.3K
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