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Christopher J. Schofield

Department of Chemistry

112H-index
1.3KPaper Count
6.3WCitation Count
Published Papers 474
Publication Date
Human carbonic anhydrase II as a versatile biocatalyst for the synthesis of chiral aryl-1,2-diols
err2026-07-28
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errOAAI
errLaura Edit Barabás; Diana Maria Scrob; Monica Ioana Toşa; Jürgen Brem; László Poppe; Christopher J. Schofield; Csaba Paizs
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Substrate-Selective Inhibition of the SARS-CoV-2 Papain-Like Protease: Inhibition of Hydrolysis of Human Over Viral Substrates
err2026-06-12
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errOAAI
errSakshi Sharma; Peter A. C. Wing; Wojtek Trede; Shyam Basak; Simeon D. Draganov; Taylah Andrews-Clark; Eidarus Salah; Petra Lukacik; Claire Strain-Damerell; Adán Pinto-Fernández; Martin A. Walsh; Fernanda Duarte; Christopher J. Schofield; Lennart Brewitz
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Beyond Histone Demethylation: Mechanisms of N-Alkyl Consecutive Oxidations by the Non-Heme Fe(II)/2-Oxoglutarate Oxygenase KDM6B
errJACS Au
IF8.7
err2026-06-06
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errOAAI
errSimahudeen Bathir Jaber Sathik Rifayee; Sudheesh Devadas; Midhun George Thomas; Bhargav Varada; Ethan Sommer; Cassandra Talaba; Christopher Schofield; Christo Z. Christov
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Development of Water-Trapping Pyrrole-2-carboxylic Acids as Broad-Spectrum Metallo-β-lactamase Inhibitors
err2026-05-14
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errOAAI
errMonisha Singha; Liam A. Wilson; Elisabete C. C. M. Moura; Maria M. Trush; Karina Calvopina; Gurleen Kaur; Greta Zaborskytė; Toms Kalniņš; Tharindi Panduwawala; Matthew J. Bowen; Matthew J. Beech; Jürgen Brem; Peter J. McHugh; Edgars Suna; Timothy R. Walsh; Christopher J. Schofield; Alistair J. M. Farley
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Structure-guided optimisation of fenofibrate-derived oxidative phosphorylation inhibitors to modify tumour hypoxia
err2026-04-29
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errOAAI
errJames P. Holt-Martyn †; Nicole Machado †; James T. T. Coates; Rathi Puliyadi; Thomas Ashton; Elysia Traynor; Samina Aslam; Thomas K. Wise; Gonzalo Rodriguez-Berriguete; Christopher J. Schofield; Geoff S. Higgins
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β-Lactam antibiotics and β-lactamases: historical perspectives and a review of β-lactamase inhibitors derived from natural products
err2026-04-23
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errOAAI
errPhanankosi Moyo †; Ikhane O. Albert †; Neo Hlungwani; Thulani Sibanda; Perfoy Lumu; Ndivhuwo Kevin Khorommbi; Gurleen Kaur; Karina Calvopina Tapia; George Siegwart; Nana Kwaku Buabeng; Cynthia A. Danquah; Lyndy J. McGaw; Sekelwa Cosa; Christopher J. Schofield; Vinesh J. Maharaj
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KDM3A catalyses the oxidation of acetyl-lysine to hydroxyacetyl-lysine on histone H3K9
err2026-04-15
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errOAAI
errRoman Belle; John-Paul Bukowski; Rachel Schiller; Ronald Cutler; Eidarus Salah; Robert S. Dawber; Anthony Tumber; Joanna Bonnici; Jessica D. Kindrick; Loane Serrano; Patrick Rabe; Catrine Johansson; Marie-Hélène Ruchaud; Richard J. Hopkinson; William D. Figg, Sr; Paul E. Brennan; David R. Mole; Simone Sidoli; Akane Kawamura; Christopher J. Schofield
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JmjC Histone Demethylases: Beyond Histone Lysine Demethylation
errCHIMIA
IF1.6
err2026-03-01
err1
PREAI
errBonnici, Joanna; Schofield, Christopher J.; Kawamura, Akane
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Structural basis of the promiscuity of the unusual Fe(II) and 2-oxoglutarate dependent human aspartate/asparagine-β-hydroxylase
err2026-02-25
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errOAAI
errMariska de Munnik; Amelia Brasnett; Tiankun Zhou; William Myers; Yicheng Wang; Kuntal Chatterjee; Anthony Tumber; Stephen A. Marshall; Philipp S. Simon; Pierre Aller; Anastasiia Shilova; Danny Axford; Hiroki Makita; Daniel W. Paley; Vandana Tiwari; Alexander T. Stead; Sebastian Dehe; Humberto Sanchez; Daniel J. Rosenberg; Roberto Alonso-Mori; Asmit Bhowmick; Junko Yano; Vittal K. Yachandra; Jaehyun Park; Sehan Park; Allen M. Orville; Lennart Brewitz; Jan F. Kern; Christopher J. Schofield; Patrick Rabe
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Expanding the Alkene-Forming Capability of the Pseudomonas Savastanoi Ethylene-Forming Enzyme
err2026-01-14
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errOAAI
errSiddhant Dhingra; Yihong Sun; Zhihong Zhang; Christopher J. Schofield; Lennart Brewitz
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In Vitro and In Vivo Evaluation of Nitroxoline as an Effective Antimicrobial Alternative to Poultry Production
err2026-01-07
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errOAAI
errYuqing Zhou; Maria M. Trush; Lewis Ibbotson; Laura Espina; Aditya Kumar Lankapalli; Alistair J. M. Farley; Huangwei Song; Congming Wu; Xingyuan Cao; Xi Xia; Charlotte J. Gray-Hammerton; Alice Moorey; Amelie Delaitre; George Siegwart; Shaolin Wang; Yang Wang; Jianzhong Shen; Christopher J. Schofield; Timothy R. Walsh
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Structural and functional consequences of aspartate/asparagine-β-hydroxylase variants causing Traboulsi Syndrome
err2025-12-05
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errOAAI
errCynthia X. Hou; Amelia Brasnett; Patrick Rabe; Christopher J. Schofield; Lennart Brewitz
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Cellular and functional insights into FIH-mediated hydroxylation of TRPA1
err2025-11-04
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errOAAI
errTao Guo; Dianne Marquez Lopez; Siyuan Wang; Liudi Yao; Xi Li; Elizabeth R. Davies; Mariana Vargas-Caballero; Nullin Divecha; Christopher J. Schofield; Katrin Deinhardt; Yihua Wang
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Small but powerful
err2025-11-04
err0
PREAI
errAndrew V. Stachulski; Christopher J. Schofield
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Profiling Inhibitor Scaffolds for the Cancer Target Jumonji-C Domain-Containing Protein 6
err2025-10-31
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errOAAI
errThomas P. Corner; Eidarus Salah; Anthony Tumber; James P. Holt-Martyn; Lennart Brewitz; Christopher J. Schofield
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C6-Alkoxy substituted penicillins are potent non-covalently binding inhibitors of the SARS-CoV-2 main protease
err2025-10-27
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errOAAI
errDorian-Gabriel Muntean; Wojtek Treyde; Linda Kinena; Eidarus Saleh; Hani Choudhry; Fernanda Duarte; Lennart Brewitz; Christopher J Schofield
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Evidence human FTO catalyses hydroxylation of <i>N</i>6-methyladenosine without direct formation of a demethylated product contrasting with ALKBH5/2/3 and bacterial AlkB
err2025-08-28
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errOAAI
errSimranjeet Kaur; Pratheesh Maheswaran; Samanpreet Kaur; Yingqi Lai; Eidarus Salah; Dong Zhang; Shifali Shishodia; Christopher J Schofield; Wei Shen Aik
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Revealing the catalytic mechanism of the Fe(II)/2-oxoglutarate-dependent human epigenetic modifying enzyme ALKBH5
err2025-08-12
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errOAAI
errFathima Hameed Cherilakkudy; Midhun George Thomas; Ann Varghese; Sodiq O. Waheed; Anandhu Krishnan; Vincenzo Venditti; Christopher J. Schofield; Deyu Li; Christo Z. Christov; Tatyana G. Karabencheva-Christova
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Electrostatic interactions influence diazabicyclooctane inhibitor potency against OXA-48-like β-lactamases
err2025-08-09
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errOAAI
errJoseph Francis Hoff; Kirsty Elizabeth Goudar; Karina Calvopiña; Michael Beer; Philip Hinchliffe; John Shaw; Catherine Louise Tooke; Yuiko Takebayashi; Andrew Cadzow; Nicholas Harmer; Adrian John Mulholland; Christopher J Schofield; James Spencer
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Investigating the N-terminal linker histone H1 subtypes as substrates for JmjC lysine demethylases
err2025-08-06
err0
errOAAI
errVildan Turkmen; Anthony Tumber; Eidarus Saleh; Samanpreet Kaur; Christopher J Schofield; Jasmin Mecinović
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