Gregory M. Cook - Publications, H-index & Citations

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Gregory M. Cook

University of Otago

64H-index

386Paper Count

1.4WCitation Count

Published Papers 170

Publication Date

Development of Thieno[2,3-b]pyridin-6(7H)-one derivatives against drug-resistant Mycobacterium tuberculosis

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2026-04-11

PREAI

Qin Zha; Zhiyong Liu; Wanwen Li; Yihuan Zhou; Matthew B. McNeil; Gregory M. Cook; Tianyu Zhang; Niuniu Zhang

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ClpC1-targeting peptide natural products differentially dysregulate the proteome of Mycobacterium tuberculosis

Nature Communications

IF15.7

2026-01-29

OAAI

Isabel K. Barter; Max J. Bedding; Julia Leodolter; Joshua W. C. Maxwell; Paige M. E. Hawkins; Maxwell T. Stevens; Matthew B. McNeil; William J. Jowsey; Trixie Wang; Diana Quan; Sabryna Junker; Manuela Flórido; Daniel Hesselson; Gregory M. Cook; Tim Clausen; Warwick J. Britton; Mark Larance; Richard J. Payne

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Design; synthesis and biological activity of potential retrometabolic polymyxins via thiol–ene chemistry

Chem. Commun.

IF0

2025-12-04

PREAI

Catherine Smith; Andrew Siow; Renata Kowalczyk; Scott A. Ferguson; Matigan J. B. Smith; Gregory M. Cook; Veronika Sander; Alan J. Davidson; Margaret A. Brimble; Paul W. R. Harris

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Remission spectroscopy resolves the mechanism of action of bedaquiline within living mycobacteria

Nature Communications

IF15.7

2025-11-25

OAAI

Suzanna H. Harrison; Rowan C. Walters; Chen-Yi Cheung; Roger J. Springett; Gregory M. Cook; Morwan M. Osman; James N. Blaza

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Advancing the antituberculosis activity of nitropicolinic acids and amides

European Journal of Medicinal Chemistry

IF5.9

2025-10-29

OAAI

Andrew M. Thompson; Chen-Yi Cheung; Matthew B. McNeil; Ashley C. Campbell; Monika Záhorszká; Jana Korduláková; Giovanni Stelitano; Deborah Recchia; Maria Rosalia Pasca; Baojie Wan; Shahebraj Khan; Dejan S. Nikolic; Gauri S. Shetye; Scott G. Franzblau; William A. Denny; Gregory M. Cook; Kurt L. Krause

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ClpC1 Modulating Ohmyungsamycin A and Ecumicin Natural Product Analogues are Potent Antimycobacterials

ACS Infectious Diseases

IF3.8

2025-10-23

PREAI

Paige M. E. Hawkins; Max J. Bedding; David M. Hoi; Isabel K. Barter; Chen-Yi Cheung; Stefan H. Oehlers; Gregory M. Cook; Tim Clausen; Warwick J. Britton; Richard J. Payne

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Beyond the 2+2 Pharmacophore Electronic and Hydrophobic Effects Control the Activity of Cationic Amphiphilic Antimicrobial 2,5-Diketopiperazines

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2025-10-01

PREAI

Siu, Christy; Siew, Tashia; Li, Freda F.; Mros, Sonya; Cleary, Caitlin S. B.; Ferguson, Scott A.; Cook, Gregory M.; Cahill, Patrick; Brimble, Margaret A.; Svenson, Johan; Rennison, David

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Comparative genomics of endemic Staphylococcus aureus ST1 in New Zealand

MSPHERE

IF3.1

2025-09-01

PREAI

Voss, Emma M.; Cook, Gregory M.; Couldrey, Christine; Ferguson, Scott A.; Harland, Chad; Karkaba, Ali; Mcdougall, Scott; Morales, Sergio E.; Rolfe, Jack; Ussher, James E.; White, Rhys T.; Williams, Liam; Williamson, John

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Whole genome sequencing reveals novel resistance-conferring mutations and large genome deletions in drug-resistant Mycobacterium tuberculosis isolates from Indonesia

Journal of Global Antimicrobial Resistance

IF3.2

2025-07-22

OAAI

Htin Lin Aung; Lidya Chaidir; Dian Ayu Eka Pitaloka; Yugen Miyahara; Narender Kumar; Arto Yuwono Soeroto; Greg M Cook; Reinout van Crevel; Bachti Alisjahbana; Sharon J. Peacock; Philip C Hill

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Verapamil and its metabolite norverapamil inhibit the Mycobacterium tuberculosis MmpS5L5 efflux pump to increase bedaquiline activity

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2025-04-17

OAAI

Fountain, Adam J.; Waller, Natalie J. E.; Cheung, Chen - Yi; Jowsey, William; Chrisp, Michael T.; Troll, Mark; Edelstein, Paul H.; Cook, Gregory M.; Ramakrishnan, Lalita

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Structure of Mycobacterial NDH-2 Bound to a 2-Mercapto-Quinazolinone Inhibitor

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2025-03-21

OAAI

Liang, Yingke; Bueler, Stephanie A.; Cook, Gregory M.; Rubinstein, John L.

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Development of tolerance to bedaquiline by overexpression of trypanosomal acetate: succinate CoA transferase in Mycobacterium smegmatis

COMMUNICATIONS BIOLOGY

IF5.1

2025-02-06

OAAI

Bundutidi, Gloria Mavinga; Mochizuki, Kota; Matsuo, Yuichi; Hayashishita, Mizuki; Sakura, Takaya; Ando, Yuri; Cook, Gregory Murray; Rajib, Acharjee; Bringaud, Frederic; Boshart, Michael; Hamano, Shinjiro; Sekijima, Masakazu; Hirayama, Kenji; Kita, Kiyoshi; Inaoka, Daniel Ken

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A novel non-invasive murine model for rapidly testing drug activity via inhalation administration against Mycobacterium tuberculosis

FRONTIERS IN PHARMACOLOGY

IF4.8

2025-01-03

OAAI

Tian, Xirong; Gao, Yamin; Li, Chunyu; Ma, Wanli; Zhang, Jingran; Ju, Yanan; Ding, Jie; Zeng, Sanshan; Hameed, H. M. Adnan; Aung, Htin Lin; Zhong, Nanshan; Cook, Gregory M.; Hu, Jinxing

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Whole genome CRISPRi screening identifies druggable vulnerabilities in an isoniazid resistant strain of Mycobacterium tuberculosis

NATURE COMMUNICATIONS

IF15.7

2024-11-13

OAAI

Wang, Xinyue; Jowsey, William J.; Cheung, Chen-Yi; Smart, Caitlan J.; Klaus, Hannah R.; Seeto, Noon E. J.; Waller, Natalie J. E.; Chrisp, Michael T.; Peterson, Amanda L.; Ofori-Anyinam, Boatema; Strong, Emily; Nijagal, Brunda; West, Nicholas P.; Yang, Jason H.; Fineran, Peter C.; Cook, Gregory M.; Jackson, Simon A.; McNeil, Matthew B.

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Phenotypic-Based Discovery and Exploration of a Resorufin Scaffold with Activity against Mycobacterium tuberculosis

CHEMMEDCHEM

IF3.4

2024-10-25

OAAI

Tran, Eric; Cheung, Chen-Yi; Li, Lucy; Carter, Glen P.; Gable, Robert W.; West, Nicholas P.; Kaur, Amandeep; Gee, Yi Sing; Cook, Gregory M.; Baell, Jonathan B.; Joerg, Manuela

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Identification of Chemical Scaffolds That Inhibit the Mycobacterium tuberculosis Respiratory Complex Succinate Dehydrogenase

ACS INFECTIOUS DISEASES

IF3.8

2024-09-13

PREAI

Adolph, Cara; Hards, Kiel; Williams, Zoe C.; Cheung, Chen-Yi; Keighley, Laura M.; Jowsey, William J.; Kyte, Matson; Inaoka, Daniel Ken; Kita, Kiyoshi; Mackenzie, Jared S.; Steyn, Adrie J. C.; Li, Zhengqiu; Yan, Ming; Tian, Guo-Bao; Zhang, Tianyu; Ding, Xiaobo; Furkert, Daniel P.; Brimble, Margaret A.; Hickey, Anthony J. R.; McNeil, Matthew B.; Cook, Gregory M.

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Remission cytochrome spectroscopy reveals the mode of action of bedaquiline in living mycobacteria

BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

IF2.7

2024-09-01

PREAI

Harrison, Suzanna H.; Walters, Rowan C.; Osman, Morwan M.; Springett, Roger J.; Cook, Gregory M.; Blaza, James N.

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Discovery of dual-targeting bioenergetic inhibitors to produce fast-acting antimicrobials for the rapid treatment of tuberculosis disease

BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

IF2.7

2024-09-01

PREAI

Cook, Gregory Murray

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Marine sponge microbe provides insights into evolution and virulence of the tubercle bacillus

PLOS PATHOGENS

IF4.9

2024-08-29

OAAI

Pidot, Sacha J.; Klatt, Stephan; Ates, Louis S.; Frigui, Wafa; Sayes, Fadel; Majlessi, Laleh; Izumi, Hiroshi; Monk, Ian R.; Porter, Jessica L.; Bennett-Wood, Vicki; Seemann, Torsten; Otter, Ashley; Taiaroa, George; Cook, Gregory M.; West, Nicholas; Tobias, Nicholas J.; Fuerst, John A.; Stutz, Michael D.; Pellegrini, Marc; McConville, Malcolm; Brosch, Roland; Stinear, Timothy P.

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Allenamides as a Powerful Tool to Incorporate Diversity: Thia-Michael Lipidation of Semisynthetic Peptides and Access to β-Keto Amides

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

IF16.9

2024-08-22

OAAI

Na, Tae-Ung; Sander, Veronika; Davidson, Alan J.; Lin, Rolland; Hermant, Yann O.; Hardie Boys, Madeleine T.; Pletzer, Daniel; Campbell, Georgia; Ferguson, Scott A.; Cook, Gregory M.; Allison, Jane R.; Brimble, Margaret A.; Northrop, Brian H.; Cameron, Alan J.

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Research Directions