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J

Jacob Leander

astrazeneca

8H-index
34Paper Count
338Citation Count
Published Papers 15
Publication Date
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Pharmacokinetics and safety of tezepelumab in children with mild, moderate or severe asthma and adolescents with mild-to-moderate asthma
errBritish Journal of Clinical Pharmacology
IF3
err2026-07-06
err0
errOAAI
errAnna Lundahl; Jonathan Grigg; Lubna Abuqayyas; Piotr Kuna; Gillian Hunter; Beata Pawlikowska; Jacob Leander; Michael Levin; Atul Gupta; James Paton; Katharine C. Pike; Jane R. Parnes; Gun Almqvist; Stephanie L. Roseti; the study investigators
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errSave
Modeling Peak Expiratory Flow in Patients With Asthma and Quantifying Treatment Effects Using a Mixed-Effects Hidden Markov Model
errcpt: pharmacometrics & systems pharmacology
IF0
err2026-06-06
err0
errOAAI
errLudvig Jakobsson; Marcus Baaz; Jacob Leander; Philip Gerlee; Mats Jirstrand
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errSave
Population Pharmacokinetics of the Novel Myeloperoxidase Inhibitor Mitiperstat
errPharmacology Research & Perspectives
IF2.3
err2026-05-08
err0
errOAAI
errMikael Sunnåker; Jacob Leander; Hans Ericsson
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errSave
Preclinical characterization of AZD1163, a first-in-class anti-PAD2/4 bispecific antibody for the treatment of rheumatoid arthritis
errmAbs
IF7.3
err2026-04-15
err0
errOAAI
errGary P. Sims; Lacie Scaletta; John Andrews; Dorothy A. Sims; Martin Strain; Anna Sigurdardottir; Teneema Kuriakose; Elizabeth England; Lichchavi Rajasinghe; Fanyi Jiang; Ximing Xiong; Frances Neal; Lisa Vinall; Philip Newton; Elin Boger; Chong Kim; Helena Dahlbäck; Susanne Prothon; Jacob Leander; Erika Darrah; Mia Collins; Garry Douglas; Nicholas White; Katie Day; Katherine A. Vousden; Catherine E. Huntington; David Close
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Elarekibep, an inhaled anti-IL-4 receptor alpha Anticalin, in moderate-to-severe asthma: a randomized, placebo-controlled phase 2a study (APATURA)
errRespiratory Research
IF5
err2026-04-14
err0
errOAAI
errTania Hugo; Andrew R Harper; Jacob Leander; Philip Gardiner; Robert Palmér; Pål Lundin; David Bock; Xiao-Hong Zhou; Irina Bondarenko; Steve Burns; Erol Wiegert; Mary F Fitzgerald; David R Close; David J Keeling; Hitesh Pandya; Maria G Belvisi; Paul M O’Byrne
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A machine learning approach to population pharmacokinetic modelling automation
errCommunications Medicine
IF6.3
err2025-07-31
err0
errOAAI
errSam Richardson; Itziar Irurzun Arana; Andrzej Nowojewski; Diansong Zhou; Jacob Leander; Weifeng Tang; Richard Dearden; Megan Gibbs
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errSave
Pharmacokinetics, pharmacodynamics and safety of tezepelumab in children with asthma
errEUROPEAN RESPIRATORY JOURNAL
IF21
err2024-10-30
err0
PREAI
errLundahl, Anna; Grigg, Jonathan; Hunter, Gillian; Pawlikowska, Beata; Chen, Cecil; Leander, Jacob; Levin, Michael; Gupta, Atul; Paton, James; Pike, Katharine C.; Abuqayyas, Lubna; Latchman, Mickel; Roseti, Stephanie L.
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errSave
APATURA: a Phase 2a study of elarekibep, an inhaled IL-4 receptor alpha inhibitor, in moderate-to-severe asthma
errEUROPEAN RESPIRATORY JOURNAL
IF21
err2024-10-30
err0
PREAI
errHugo, Tania; Harper, Andrew R.; Leander, Jacob; Lundin, Pa; Bock, David; Zhou, Xiao-Hong; Bondarenko, Irina; Burns, Steve; Wiegert, Erol; Fitzgerald, Mary F.; Close, David R.; Keeling, David J.; Pandya, Hitesh; Belvisi, Maria G.; O'Byrne, Paul M.
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A stochastic mixed effects model to assess treatment effects and fluctuations in home-measured peak expiratory flow and the association with exacerbation risk in asthma
errCPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY
IF3
err2021-12-13
err2
errOAAI
errLeander, Jacob; Jirstrand, Mats; Eriksson, Ulf G.; Palmer, Robert
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errSave
Estimation of Equipotent Doses for Anti-Inflammatory Effects of Prednisolone and AZD9567, an Oral Selective Nonsteroidal Glucocorticoid Receptor Modulator
errCPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY
IF3
err2020-08-19
err8
errOAAI
errAlmquist, Joachim; Sadiq, Muhammad Waqas; Eriksson, Ulf G.; Myrback, Tove Hegelund; Prothon, Susanne; Leander, Jacob
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errSave
Effects of a selective glucocorticoid receptor modulator (AZD9567) versus prednisolone in healthy volunteers: two phase 1, single-blind, randomised controlled trials
errLANCET RHEUMATOLOGY
IF16.4
err2020-01-01
err15
PREAI
errMyrback, Tove Hegelund; Prothon, Susanne; Edman, Karl; Leander, Jacob; Hashemi, Mahdi; Dearman, Matthew; Edenro, Goran; Svanberg, Petter; Andersson, Eva-Marie; Almquist, Joachim; Ammala, Carina; Hendrickx, Ramon; Taib, Ziad; Johansson, Kicki A.; Berggren, Anders R.; Keen, Christina M.; Eriksson, Ulf G.; Fuhr, Rainard; Carlsson, Bjorn C. L.
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URINARY LEUKOTRIENE E4 (ULTE4) PHARMACODYNAMIC BIOMARKER FOR EARLY DECISION MAKING IN THE AZD9898 ADAPTIVE PHASE I STUDY
errTHORAX
IF7.7
err2018-11-16
err1
PREAI
errBetts, J.; Larsson, B.; Jauhiainen, A.; Hegelund-Myrback, T.; Leander, J.; Berton, A.; Glader, P.; Holmberg, A. Aurell; Santisteban, Z.; Franzen, J.; Albayaty, M.; Keen, C.; Kristensson, C.
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errSave
Exact Gradients Improve Parameter Estimation in Nonlinear Mixed Effects Models with Stochastic Dynamics
errAAPS JOURNAL
IF3.7
err2018-08-01
err7
errOAAI
errOlafsdottir, Helga Kristin; Leander, Jacob; Almquist, Joachim; Jirstrand, Mats
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errSave
Mixed Effects Modeling Using Stochastic Differential Equations: Illustrated by Pharmacokinetic Data of Nicotinic Acid in Obese Zucker Rats
errAAPS JOURNAL
IF3.7
err2015-02-19
err29
errOAAI
errLeander, Jacob; Almquist, Joachim; Ahlstrom, Christine; Gabrielsson, Johan; Jirstrand, Mats
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errSave
Joint Feedback Analysis Modeling of Nonesterified Fatty Acids in Obese Zucker Rats and Normal Sprague-Dawley Rats after Different Routes of Administration of Nicotinic Acid
errJOURNAL OF PHARMACEUTICAL SCIENCES
IF3.8
err2014-08-01
err7
errOAAI
errTapani, Sofia; Almquist, Joachim; Leander, Jacob; Ahlstrom, Christine; Peletier, Lambertus A.; Jirstrand, Mats; Gabrielsson, Johan
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errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
P
Paul M. O’Byrne
H-index: 111 · Papers: 885
M
Maria G. Belvisi
H-index: 79 · Papers: 412
L
L. A. Peletier
H-index: 56 · Papers: 318
B
Björn Carlsson
H-index: 53 · Papers: 216
K
K. A. P. Edman
H-index: 50 · Papers: 178
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