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J

Jiekun Yang

broad institute of massachusetts institute of technology

18H-index
62Paper Count
1.3KCitation Count
Published Papers 24
Publication Date
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Author Correction: Specific oncogene activation of the cell of origin in mucosal melanoma
errNature Communications
IF15.7
err2026-08-20
err0
errOAAI
errSwathy Babu; Jiajia Chen; Chloé S. Baron; Kaiwen Sun; Emily Robitschek; Alicia M. McConnell; Constance Wu; Aikaterini Dedeilia; Moshe Sade-Feldman; Rodsy Modhurima; Michael P. Manos; Kevin Y. Chen; Anna M. Cox; Calvin G. Ludwig; Manolis Kellis; Elizabeth I. Buchbinder; Nir Hacohen; Jiekun Yang; Genevieve M. Boland; Brian J. Abraham; David Liu; Leonard I. Zon; Megan L. Insco
errShare
errSave
Impaired nitrogenous waste clearance promotes hepatocellular carcinoma
errScience Advances
IF12.5
err2026-01-09
err1
PREAI
errHan, Xinlu; Shen, Jianliang; Yan, Junrong; Tacke, Rahul; Dai, Weiwei; Mao, Qingqing; Queen Daguplo, Heineken; Liu, Shuyang; Islam, Ariful; Liu, Tong; Koch, Mark C.; Lin, Richard Z.; Li, Hong; Anthony, Tracy; Xie, Ping; Zhang, Lanjing; Gao, Shenglan; Simon, M. Celeste; Chen, Xin; Yang, Jiekun; Su, Xiaoyang; Zong, Wei-Xing
errShare
errSave
Mature and migratory dendritic cells promote immune infiltration and response to anti-PD-1 checkpoint blockade in metastatic melanoma
errNature Communications
IF15.7
err2025-09-01
err0
errOAAI
errJiekun Yang; Cassia Wang; Doris Fu; Li-Lun Ho; Kyriakitsa Galani; Lee Chen; Jose Gonzalez; Jolene Fu; Amy Y. Huang; Dennie T. Frederick; Liang He; Mukta Asnani; Rahul Tacke; Emily J. Robitschek; Sandeep K. Yadav; Wentao Deng; Kelly P. Burke; Tatyana Sharova; Ryan J. Sullivan; Sarah Weiss; Kunal Rai; David Liu; Genevieve M. Boland; Manolis Kellis
errShare
errSave
Overcoming resistance to immunotherapy by targeting CD38 in human tumor explants
errCell Reports Medicine
IF10.6
err2025-06-27
err0
errOAAI
errOr-Yam Revach; Angelina M. Cicerchia; Ofir Shorer; Claire A. Palin; Boryana Petrova; Seth Anderson; Baolin Liu; Joshua Park; Lee Chen; Arnav Mehta; Samuel J. Wright; Niamh McNamee; Aya Tal-Mason; Giulia Cattaneo; Payal Tiwari; Hongyan Xie; Johanna M. Sweere; Li-Chun Cheng; Natalia Sigal; Elizabeth Enrico; Marisa Miljkovic; Shane A. Evans; Ngan Nguyen; Mark E. Whidden; Ramji Srinivasan; Matthew H. Spitzer; Yi Sun; Tatyana Sharova; Aleigha R. Lawless; William A. Michaud; Martin Q. Rasmussen; Jacy Fang; Jeannette R. Brook; Feng Chen; Xinhui Wang; Cristina R. Ferrone; Donald P. Lawrence; Ryan J. Sullivan; David Liu; Uma M. Sachdeva; Debattama R. Sen; Keith T. Flaherty; Robert T. Manguso; Lloyd Bod; Manolis Kellis; Genevieve M. Boland; Keren Yizhak; Jiekun Yang; Naama Kanarek; Moshe Sade-Feldman; Nir Hacohen; Russell W. Jenkins
errShare
errSave
Depletion of lamins B1 and B2 promotes chromatin mobility and induces differential gene expression by a mesoscale-motion-dependent mechanism
errGENOME BIOLOGY
IF9.4
err2024-03-22
err2
errOAAI
errLiwag, Emily M. Pujadas; Wei, Xiaolong; Acosta, Nicolas; Carter, Lucas M.; Yang, Jiekun; Almassalha, Luay M.; Jain, Surbhi; Daneshkhah, Ali; Rao, Suhas S. P.; Seker-Polat, Fidan; MacQuarrie, Kyle L.; Ibarra, Joe; Agrawal, Vasundhara; Aiden, Erez Lieberman; Kanemaki, Masato T.; Backman, Vadim; Adli, Mazhar
errShare
errSave
Antigen presenting cells in cancer immunity and mediation of immune checkpoint blockade
errCLINICAL & EXPERIMENTAL METASTASIS
IF3.2
err2024-01-23
err1
errOAAI
errWang, Cassia; Chen, Lee; Fu, Doris; Liu, Wendi; Puri, Anusha; Kellis, Manolis; Yang, Jiekun
errShare
errSave
Dissecting the tumor microenvironment in response to immune checkpoint inhibitors via single-cell and spatial transcriptomics
errCLINICAL & EXPERIMENTAL METASTASIS
IF3.2
err2023-12-08
err5
errOAAI
errLiu, Wendi; Puri, Anusha; Fu, Doris; Chen, Lee; Wang, Cassia; Kellis, Manolis; Yang, Jiekun
errShare
errSave
Functional roles of enhancers in immune microenvironment & immunotherapy response
errCANCER RESEARCH
IF16.6
err2023-04-04
err0
PREAI
errRai, Kunal; Maitituoheti, Mayinuer; Shi, Alvin; Tang, Ming; Ho, Li-Lun; Kreidieh, Firas Youssef; Terranova, Christopher; Galani, Kyriakitsa; Keung, Emily Z.; Creasy, Caitlin A.; Wu, Manrong; Chen, Jiajia; Chen, Nana; Singh, Anand K.; Chaudhri, Apoorvi; Anvar, Nazanin E.; Tarrantino, Giuseppe; Yang, Jiekun; Sarkar, Sharmistha; Jiang, Shan; Malke, Jared; Haydu, Lauren; Burton, Elizabeth; Davies, Michael A.; Gershenwald, Jeffrey E.; Hwu, Patrick; Lazar, Alexander; Cheah, Jaime H.; Soule, Christian K.; Levine, Stuart S.; Bernatchez, Chantale; Saladi, Srinivas V.; Liu, David; Tawbi, Hussein; Wargo, Jennifer; Boland, Genevieve M.; Kellis, Manolis
errShare
errSave
Single-cell transcriptomic and epigenomic landscapes of innate and adaptive immune cells in metastatic melanoma treated with immunotherapy
errCANCER RESEARCH
IF16.6
err2023-04-04
err0
PREAI
errYang, Jiekun; Fu, Doris; Galani, Kyriakitsa; Ho, Li-Lun; Robitschek, Emily J.; Frederick, Dennie T.; Yadav, Sandeep K.; Deng, Wentao; Singh, Anand K.; Burke, Kelly P.; Wang, Cassia; Sharova, Tatyana; Liu, David; Rai, Kunal; Boland, Genevieve M.; Kellis, Manolis
errShare
errSave
Multiomic meta-analysis of differential response to PD-1 and CTLA-4 blockade in metastatic melanoma
errCANCER RESEARCH
IF16.6
err2023-04-04
err0
PREAI
errHuang, Amy Y.; Vokes, Natalie; Ricker, Cora; Aprati, Tyler; Robitschek, Emily; Yang, Jiekun; Ho, Li-Lun; Galani, Kyriakitsa; Burke, Kelly P.; Tarantino, Giuseppe; Chen, Jiajia; Sharpe, Arlene H.; Van Allen, Eliezer M.; Kellis, Manolis; Boland, Genevieve M.; Liu, David
errShare
errSave
Exercise training remodels inguinal white adipose tissue through adaptations in innervation, vascularization, and the extracellular matrix
errCELL REPORTS
IF6.9
err2023-04-01
err13
errOAAI
errNigro, Pasquale; Vamvini, Maria; Yang, Jiekun; Caputo, Tiziana; Ho, Li-Lun; Carbone, Nicholas P.; Papadopoulos, Danae; Conlin, Royce; He, Jie; Hirshman, Michael F.; White, Joseph D.; Robidoux, Jacques; Hickner, Robert C.; Nielsen, Soren; Pedersen, Bente K.; Kellis, Manolis; Middelbeek, Roeland J. W.; Goodyear, Laurie J.
errShare
errSave
Single-cell dissection of the obesity-exercise axis in adipose-muscle tissues implies a critical role for mesenchymal stem cells
errCELL METABOLISM
IF30.9
err2022-10-01
err41
errOAAI
errYang, Jiekun; Vamvini, Maria; Nigro, Pasquale; Ho, Li-Lun; Galani, Kyriakitsa; Alvarez, Marcus; Tanigawa, Yosuke; Renfro, Ashley; Carbone, Nicholas P.; Laakso, Markku; Agudelo, Leandro Z.; Pajukanta, Paivi; Hirshman, Michael F.; Middelbeek, Roeland J. W.; Grove, Kevin; Goodyear, Laurie J.; Kellis, Manolis
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errSave
Investigation of the genetic effect of 56 tobacco-smoking susceptibility genes on DNA methylation and RNA expression in human brain
errFRONTIERS IN PSYCHIATRY
IF3.2
err2022-08-18
err2
errOAAI
errYang, Zhongli; Yang, Jiekun; Mao, Ying; Li, Ming D.
errShare
errSave
ISL2 is a putative tumor suppressor whose epigenetic silencing reprograms the metabolism of pancreatic cancer
errDEVELOPMENTAL CELL
IF8.7
err2022-06-01
err11
errOAAI
errOzturk, Harun; Cingoz, Harun; Tufan, Turan; Yang, Jiekun; Adair, Sara J.; Tummala, Krishna Seshu; Kuscu, Cem; Kinali, Meric; Comertpay, Gamze; Nagdas, Sarbajeet; Goudreau, Bernadette J.; Luleyap, Husnu Umit; Bingul, Yagmur; Ware, Timothy B.; Hwang, Wiliam L.; Hsu, Ku-lung; Kashatus, David F.; Ting, David T.; Chandel, Navdeep S.; Bardeesy, Nabeel; Bauer, Todd W.; Adli, Mazhar
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errSave
Targeted CRISPR screening identifies PRMT5 as synthetic lethality combinatorial target with gemcitabine in pancreatic cancer cells
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2020-10-23
err58
errOAAI
errWei, Xiaolong; Yang, Jiekun; Adair, Sara J.; Ozturk, Harun; Kuscu, Cem; Lee, Kyung Yong; Kane, William J.; O'Hara, Patrick E.; Liu, Denis A.; Demirlenk, Yusuf Mert; Habieb, Alaa Hamdi; Yilmaz, Ebru; Dutta, Anindya; Bauer, Todd W.; Adli, Mazhar
errShare
errSave
Chemotherapy-Induced Distal Enhancers Drive Transcriptional Programs to Maintain the Chemoresistant State in Ovarian Cancer
errCANCER RESEARCH
IF16.6
err2019-09-13
err39
errOAAI
errShang, Stephen; Yang, Jiekun; Jazaeri, Amir A.; Duval, Alexander James; Tufan, Turan; Fischer, Natasha Lopes; Benamar, Mouadh; Guessous, Fadila; Lee, Inyoung; Campbell, Robert M.; Ebert, Philip J.; Abbas, Tarek; Landen, Charles N.; Difeo, Analisa; Scacheri, Peter C.; Adli, Mazhar
errShare
errSave
Mapping and Making Sense of Noncoding Mutations in the Genome
errCANCER RESEARCH
IF16.6
err2019-09-03
err5
PREAI
errYang, Jiekun; Adli, Mazhar
errShare
errSave
Recurrent mutations at estrogen receptor binding sites alter chromatin topology and distal gene expression in breast cancer
errGENOME BIOLOGY
IF9.4
err2018-11-07
err22
errOAAI
errYang, Jiekun; Wei, Xiaolong; Tufan, Turan; Kuscu, Cem; Unlu, Hayrunnisa; Farooq, Saadia; Demirtas, Elif; Paschal, Bryce M.; Adli, Mazhar
errShare
errSave
CRISPR knockout screening identifies combinatorial drug targets in pancreatic cancer and models cellular drug response
errNATURE COMMUNICATIONS
IF15.7
err2018-10-15
err47
errOAAI
errSzlachta, Karol; Kuscu, Cem; Tufan, Turan; Adair, Sara J.; Shang, Stephen; Michaels, Alex D.; Mullen, Matthew G.; Fischer, Natasha Lopes; Yang, Jiekun; Liu, Limin; Trivedi, Prasad; Stelow, Edward B.; Stukenberg, P. Todd; Parsons, J. Thomas; Bauer, Todd W.; Adli, Mazhar
errShare
errSave
CRISPR-STOP: gene silencing through base-editing-induced nonsense mutations
errNATURE METHODS
IF32.1
err2017-06-05
err307
PREAI
errKuscu, Cem; Parlak, Mahmut; Tufan, Turan; Yang, Jiekun; Szlachta, Karol; Wei, Xiaolong; Mammadov, Rashad; Adli, Mazhar
errShare
errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
M
Markku Laakso
H-index: 171 · Papers: 1.2K
A
Arlene H. Sharpe
H-index: 154 · Papers: 737
B
Bente Klarlund Pedersen
H-index: 149 · Papers: 1.1K
K
Keith T. Flaherty
H-index: 146 · Papers: 1.7K
M
Manolis Kellis
H-index: 139 · Papers: 1.1K
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