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Gyochang Keum

korea institute of science & technology (kist)

24H-index
156Paper Count
1.8KCitation Count
Published Papers 51
Publication Date
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Lipid Nanoparticle Database towards structure-function modeling and data-driven design for nucleic acid delivery
errNature Communications
IF15.7
err2026-01-28
err0
errOAAI
errEvan Collins; Jungyong Ji; Sung-Gwang Kim; Jacob Witten; Seonghoon Kim; Richard Zhu; Peter Park; Minjun Jung; Aron Park; Rajith S. Manan; Arnab Rudra; Gyochang Keum; Eun-Kyoung Bang; Jun-O Jin; William J. Jeang; Robert Langer; Daniel G. Anderson; Wonpil Im
errShare
errSave
Enhanced Subchronic Cardiac Stress of High Doses of a Novel SARS-CoV-2 mRNA Vaccine Candidate in Streptozotocin-Induced Diabetic Mice
errFood and Chemical Toxicology
IF3.5
err2025-12-05
err0
PREAI
errHarin Jo; Subin Yoon; Sumin Cho; Eunji Lee; NaHyun Kim; Eun-Bin Choi; Inyoung Park; SiYeong Park; Na Yun Lee; Young Jeon; Hyeok-Won An; Jun Won Park; Gyochang Keum; Jae-Hwan Nam; Jun-Won Yun
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errSave
Dihydrotricetin from Euonymus hamiltonianus ameliorates neuroinflammation and exhibits neuroprotective effect in LPS-induced microglia
errBiomedicine & Pharmacotherapy
IF7.5
err2025-11-28
err0
errOAAI
errTianqi Huang; Jae Sik Yu; Gyo Chang Keum; Hyun Ok Yang
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errSave
Delivery strategies of messenger RNA therapeutics for brain disorders
errBULLETIN OF THE KOREAN CHEMICAL SOCIETY
IF2.2
err2025-11-01
err0
PREAI
errYoun, Kounghwa; Oh, Sunmin; Gil, Hyunchae; Choi, Yongseok; Keum, Gyochang; Bang, Eun-kyoung
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errSave
Protocol for in vitro transfection of mRNA-encapsulated lipid nanoparticles
errSTAR PROTOCOLS
IF1.3
err2025-10-01
err0
errOAAI
errYoun, Kounghwa; Yoo, Soyeon; Hwang, Il Kwon; Gil, Hyunchae; Park, Hayoung; Lee, Haein; Oh, Sunmin; Keum, Gyochang; Bang, Eun-Kyoung
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Artificial intelligence-driven discovery of novel scaffolds for selective TLR7 antagonists and their application in enhancing mRNA translation efficiency
errEuropean Journal of Pharmaceutical Sciences
IF4.7
err2025-06-20
err0
errOAAI
errSoyeon Yoo; Kounghwa Youn; Nawoon Kim; Gyochang Keum; Hahnbeom Park; Eun-Kyoung Bang
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errSave
Impact of administration routes and dose frequency on the toxicology of SARS-CoV-2 mRNA vaccines in mice model
errARCHIVES OF TOXICOLOGY
IF6.9
err2024-12-10
err0
errOAAI
errAhn, Jae-Hun; Lee, Jisun; Roh, Gahyun; Lee, Na-Young; Bae, Hee-Jin; Kwon, Euna; Han, Kang-Min; Kim, Ji-Eun; Park, Hyo-Jung; Yoo, Soyeon; Kwon, Sung Pil; Bang, Eun-Kyoung; Keum, Gyochang; Nam, Jae-Hwan; Kang, Byeong-Cheol
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errSave
Novel Less Toxic, Lymphoid Tissue-Targeted Lipid Nanoparticles Containing a Vitamin B5-Derived Ionizable Lipid for mRNA Vaccine Delivery
errADVANCED HEALTHCARE MATERIALS
IF9.6
err2024-11-06
err0
errOAAI
errYoo, Soyeon; Faisal, Muhammad; Bae, Seo-Hyeon; Youn, Kounghwa; Park, Hyo-Jung; Kwon, Sung Pil; Hwang, Il Kwon; Lee, Jisun; Kim, Hyeong Jun; Nam, Jae-Hwan; Keum, Gyochang; Bang, Eun-Kyoung
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errSave
A lipid nanoparticle platform incorporating trehalose glycolipid for exceptional mRNA vaccine safety
errBIOACTIVE MATERIALS
IF20.3
err2024-08-01
err6
errOAAI
errBae, Seo-Hyeon; Yoo, Soyeon; Lee, Jisun; Park, Hyo-Jung; Kwon, Sung Pil; Jin, Harin; Park, Sang-In; Lee, Yu-Sun; Bang, Yoo-Jin; Roh, Gahyun; Lee, Seonghyun; Youn, Sue Bean; Kim, In Woo; Oh, Ho Rim; El-Damasy, Ashraf K.; Keum, Gyochang; Kim, Hojun; Youn, Hyewon; Nam, Jae-Hwan; Bang, Eun-Kyoung
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errSave
Identification of Ureidocoumarin-Based Selective Discoidin Domain Receptor 1 (DDR1) Inhibitors via Drug Repurposing Approach, Biological Evaluation, and In Silico Studies
errPHARMACEUTICALS
IF4.8
err2024-03-27
err3
errOAAI
errEl-Damasy, Ashraf K.; Kim, Hyun Ji; Al-Karmalawy, Ahmed A.; Alnajjar, Radwan; Khalifa, Mohamed M.; Bang, Eun-Kyoung; Keum, Gyochang
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errSave
Identification of an Antagonist Targeting G Protein and β-Arrestin Signaling Pathways of 5-HT7R
errACS CHEMICAL NEUROSCIENCE
IF3.9
err2024-02-22
err0
PREAI
errJeong, Jeong Hyun; Lee, Haeun; Kim, Doyoung; Park, Eunseo; Woo, Jiwan; Cho, Yakdol; Keum, Gyochang; Lee, Ansoo; Kang, Taek; Kim, Jeongjin; Choo, Hyunah; Lee, Sanghee; Jeon, Byungsun
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errSave
Discovery of thiophen-2-ylmethylene bis-dimedone derivatives as novel WRN inhibitors for treating cancers with microsatellite instability
errBIOORGANIC & MEDICINAL CHEMISTRY
IF3
err2024-02-01
err2
PREAI
errYang, Hwasun; Kang, Miso; Jang, Seonyeong; Baek, Soo Yeon; Kim, Jiwon; Kim, Gyeong Un; Kim, Dongwoo; Ha, Junsu; Kim, Jong Seung; Jung, Cheulhee; Kim, Nam-Jung; Cho, Sung-Yup; Shin, Woong-Hee; Lee, Juyong; Ko, Junsu; Lee, Ansoo; Keum, Gyochang; Lee, Sanghee; Kang, Taek
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errSave
Analysis of the Immunostimulatory Effects of Cytokine-Expressing Internal Ribosome Entry Site-Based RNA Adjuvants and Their Applications
errJOURNAL OF INFECTIOUS DISEASES
IF4.5
err2023-09-15
err4
PREAI
errLee, Yu-Sun; Bang, Yoo-Jin; Yoo, Soyeon; Park, Sang-In; Park, Hyo-Jung; Kwak, Hye Won; Bae, Seo-Hyeon; Park, Hyeong-Jun; Kim, Jae-Yong; Youn, Sue-Bean; Roh, Gahyun; Lee, Seonghyun; Kwon, Sung Pil; Bang, Eun-Kyoung; Keum, Gyochang; Nam, Jae-Hwan; Hong, So-Hee
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errSave
Discovery of 3-((3-amino-1H-indazol-4-yl)ethynyl)-N-(4-((4-ethylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide (AKE-72), a potent Pan-BCR-ABL inhibitor including the T315I gatekeeper resistant mutant
errJOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
IF5.4
err2023-07-20
err0
errOAAI
errEl-Damasy, Ashraf K.; Kim, Hyun Ji; Park, Jung Woo; Nam, Yunju; Hur, Wooyoung; Bang, Eun-Kyoung; Keum, Gyochang
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errSave
Analyzing immune responses to varied mRNA and protein vaccine sequences
errNPJ VACCINES
IF6.5
err2023-06-05
err20
errOAAI
errPark, Hyeong-Jun; Bang, Yoo-Jin; Kwon, Sung Pil; Kwak, Woori; Park, Sang-In; Roh, Gahyun; Bae, Seo-Hyeon; Kim, Jae-Yong; Kwak, Hye Won; Kim, Yongkwan; Yoo, Soyeon; Kim, Daegeun; Keum, Gyochang; Bang, Eun-Kyoung; Hong, So-Hee; Nam, Jae-Hwan
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Overcoming the imatinib-resistant BCR-ABL mutants with new ureidobenzothiazole chemotypes endowed with potent and broad-spectrum anticancer activity
errJOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
IF5.4
err2023-03-17
err3
errOAAI
errEl-Damasy, Ashraf K.; Jin, Heewon; Park, Jung Woo; Kim, Hyun Ji; Khojah, Hanan; Seo, Seon Hee; Lee, Ju-Hyeon; Bang, Eun-Kyoung; Keum, Gyochang
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errSave
Discovery of new 6-ureido/amidocoumarins as highly potent and selective inhibitors for the tumour-relevant carbonic anhydrases IX and XII
errJOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
IF5.4
err2023-02-02
err9
errOAAI
errEl-Damasy, Ashraf K.; Kim, Hyun Ji; Nocentini, Alessio; Seo, Seon Hee; Eldehna, Wagdy M.; Bang, Eun-Kyoung; Supuran, Claudiu T.; Keum, Gyochang
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errSave
Identification of New N-methyl-piperazine Chalcones as Dual MAO-B/AChE Inhibitors
errPHARMACEUTICALS
IF4.8
err2023-01-06
err12
errOAAI
errEl-Damasy, Ashraf K.; Park, Jong Eun; Kim, Hyun Ji; Lee, Jinhyuk; Bang, Eun-Kyoung; Kim, Hoon; Keum, Gyochang
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errSave
Sinapic Acid Attenuates the Neuroinflammatory Response by Targeting AKT and MAPK in LPS-Activated Microglial Models
errBIOMOLECULES & THERAPEUTICS
IF3.2
err2022-11-25
err8
errOAAI
errHuang, Tianqi; Zhao, Dong; Lee, Sangbin; Keum, Gyochang; Yang, Hyun Ok
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errSave
Metal/catalyst-free sequential C-N bond forming cascades at room temperature: environment-friendly one-pot synthesis of 5-aminoimidazoles from aryl glyoxals, anilines, and amidines
errGREEN CHEMISTRY
IF9.2
err2022-01-01
err1
PREAI
errJalani, Hitesh B.; Sivaraman, Aneesh; Min, Kyoung Ho; Lee, Hwa Young; Oh, Na Kyoung; Kang, Hyeseul; Keum, Gyochang; Choi, Yongseok; Lee, Kyeong
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Research Directions

No research directions
Co-authors
Cooperation Journals
R
Róbert Langer
H-index: 262 · Papers: 2.0K
K
K. N. Houk
H-index: 157 · Papers: 2.6K
C
Claudiu T. Supuran
H-index: 152 · Papers: 4.2K
B
Bryan L. Roth
H-index: 139 · Papers: 970
J
Jong Seung Kim
H-index: 134 · Papers: 1.2K
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