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S

Sarah S. Darwish

German University in Cairo

6H-index
13Paper Count
149Citation Count
Published Papers 9
Publication Date
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Exploring Pyrazolidinone and Pyrazolidinedione Scaffolds for Alzheimer's Therapy: Multitarget COX-2 Inhibitors with Anti-Amyloid β; Anti-Tau; Antioxidant; and Neuroprotective Activities
errRSC Med. Chem.
IF3.6
err2025-11-10
err0
PREAI
errMichael Emad; Reham Waheed; Zeinab Mostafa; Sarah S Darwish; Rosa Purgatorio; Daniela V Miniero; Annalisa De Palma; Tzu-Peng Cheng; Yu-Cheng Chen; Moustafa Gabr; Ahmed M El Kerdawy; Marco Catto; Ashraf H. Abadi; Tsong-Long Hwang; Mohammad Abdel-Halim
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Revisiting COX-2 Inhibitors for Alzheimer's Disease as Multitargeted Ligands: Development of 4-Hydrazono-Pyrazolidinediones with Tuned COX Selectivity Profile and Improved Cellular Potency
errEuropean Journal of Medicinal Chemistry
IF5.9
err2025-10-13
err0
PREAI
errReham Waheed; Zeinab Moustafa; Michael Emad; Sarah S. Darwish; Rosa Purgatorio; Daniela Valeria Miniero; Annalisa De Palma; Tzu-Peng Cheng; Ting-Yu Wang; Yu-Cheng Chen; Ahmed M. El Kerdawy; Moustafa T. Gabr; Marco Catto; Ashraf H. Abadi; Tsong-Long Hwang; Mohammad Abdel-Halim
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From Dyrk1A inhibitors to a novel class of antiviral agents: Targeting Enterovirus EV-A71 with 2-aryl-substituted thiophene scaffolds
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2025-04-01
err0
PREAI
errKeddis, Parthiena M.; Tu, Tuong-Khanh My; Scherer, Hugo; Kany, Andreas M.; Hafez, Donia E.; Darwish, Sarah S.; Abadi, Ashraf H.; Hirsch, Anna K. H.; Engel, Matthias; Hamed, Mostafa M.; Horng, Jim-Tong; Abdel-Halim, Mohammad
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Novel 6-hydroxybenzothiazol-2-carboxamides as potent and selective monoamine oxidase B inhibitors endowed with neuroprotective activity
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2024-04-01
err6
errOAAI
errAl-Saad, Omar M.; Gabr, Moustafa; Darwish, Sarah S.; Rullo, Mariagrazia; Pisani, Leonardo; Miniero, Daniela Valeria; Liuzzi, Grazia Maria; Kany, Andreas M.; Hirsch, Anna K. H.; Abadi, Ashraf H.; Engel, Matthias; Catto, Marco; Abdel-Halim, Mohammad
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Development of (4-Phenylamino)quinazoline Alkylthiourea Derivatives as Novel NF-κB Inhibitors
errPHARMACEUTICALS
IF4.8
err2022-06-22
err3
errOAAI
errDarwish, Sarah S.; Chen, Po-Jen; Hamed, Mostafa M.; Wagdy, Reem A.; Chen, Shun-Hua; Abadi, Ashraf H.; Abdel-Halim, Mohammad; Hwang, Tsong-Long; Engel, Matthias
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Development of novel amide-derivatized 2,4-bispyridyl thiophenes as highly potent and selective Dyrk1A inhibitors. Part II: Identification of the cyclopropylamide moiety as a key modification
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2018-10-01
err17
PREAI
errDarwish, Sarah S.; Abdel-Halim, Mohammad; ElHady, Ahmed K.; Salah, Mohamed; Abadi, Ashraf H.; Becker, Walter; Engel, Matthias
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errSave
Development of novel 2,4-bispyridyl thiophene-based compounds as highly potent and selective Dyrk1A inhibitors. Part I: Benzamide and benzylamide derivatives
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2018-09-01
err20
PREAI
errDarwish, Sarah S.; Abdel-Halim, Mohammad; Salah, Mohamed; Abadi, Ashraf H.; Becker, Walter; Engel, Matthias
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First Bispecific Inhibitors of the Epidermal Growth Factor Receptor Kinase and the NF-κB Activity As Novel Anticancer Agents
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2017-03-28
err29
errOAAI
errHamed, Mostafa M.; Darwish, Sarah S.; Herrmann, Jennifer; Abadi, Ashraf H.; Engel, Matthias
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Pharmacological inhibition of protein kinase C (PKC)ζ downregulates the expression of cytokines involved in the pathogenesis of chronic obstructive pulmonary disease (COPD)
errEUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
IF4.7
err2016-10-01
err13
PREAI
errAbdel-Halim, Mohammad; Darwish, Sarah S.; ElHady, Ahmed K.; Hoppstaedter, Jessica; Abadi, Ashraf H.; Hartmann, Rolf W.; Kiemer, Alexandra K.; Engel, Matthias
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Research Directions

No research directions
Co-authors
Cooperation Journals
R
Rolf W. Hartmann
H-index: 60 · Papers: 507
T
Tsong‐Long Hwang
H-index: 58 · Papers: 711
W
Walter Becker
H-index: 50 · Papers: 258
A
Alexandra K. Kiemer
H-index: 48 · Papers: 210
陈玉成 cover
陈玉成 (Yu‐Cheng Chen)
H-index: 46 · Papers: 413
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