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SaveSpatial genomics reveals cholesterol metabolism as a key factor in colorectal cancer immunotherapy resistance
Kavran, Andrew J.; Bai, Yulong; Rabe, Brian; Kreshock, Anna; Fisher, Andrew; Cheng, Yelena; Lewin, Anne; Dai, Chao; Meyer, Matthew J.; Mavrakis, Konstantinos J.; Lyubetskaya, Anna; Drokhlyansky, Eugene Share Save Discovery and characterization of a selective IKZF2 glue degrader for cancer immunotherapyBonazzi, Simone; d'Hennezel, Eva; Beckwith, Rohan E. J.; Xu, Lei; Fazal, Aleem; Magracheva, Anna; Ramesh, Radha; Cernijenko, Artiom; Antonakos, Brandon; Bhang, Hyo-eun C.; Caro, Roxana Garcia; Cobb, Jennifer S.; Ornelas, Elizabeth; Ma, Xiaolei; Wartchow, Charles A.; Clifton, Matthew C.; Forseth, Ry R.; Fortnam, Bethany Hughes; Lu, Hongbo; Csibi, Alfredo; Tullai, Jennifer; Carbonneau, Seth; Thomsen, Noel M.; Larrow, Jay; Chie-Leon, Barbara; Hainzl, Dominik; Gu, Yi; Lu, Darlene; Meyer, Matthew J.; Alexander, Dylan; Kinyamu-Akunda, Jacqueline; Sabatos-Peyton, Catherine A.; Dales, Natalie A.; Zecri, Frederic J.; Jain, Rishi K.; Shulok, Janine; Wang, Y. Karen; Briner, Karin; Porter, Jeffery A.; Tallarico, John A.; Engelman, Jeffrey A.; Dranoff, Glenn; Bradner, James E.; Visser, Michael; Solomon, Jonathan M. Share Save CRISPR screening identifies T cell-intrinsic regulators of CD3-bispecific antibody responsesMolony, Ryan D. D.; Funk, Theresa; Trabucco, Gina; Corcoran, Erik; Ruddy, David; Varadarajan, Malini; Elliot, GiNell; Piquet, Michelle; Lam, Joni; Meyer, Matthew J. J.; Wang, Hui Qin; Kurtulus, Sema; Lu, Haihui Share Save Share Save Share Save Share Save Share Save Development of Anti-CD32b Antibodies with Enhanced Fc Function for the Treatment of B and Plasma Cell MalignanciesLu, Haihui; Molony, Ryan D.; Chen, Dongshu; Jang, Sunyoung; Wolf, Babette; Ewert, Stefan; Flaherty, Meghan; Xu, Fangmin; Isim, Sinan; Shim, Yeonju; Dornelas, Christina; Balke, Nicole; Leber, Xavier Charles; Scharenberg, Meike; Koelln, Johanna; Choi, Eugene; Ward, Rebecca; Johnson, Jennifer; Calzascia, Thomas; Isnardi, Isabelle; Williams, Juliet A.; Lindenbergh, Pieter L.; van de Donk, Niels W. C. J.; Mutis, Tuna; Huet, Heather; Lees, Emma; Meyer, Matthew J. Share Save Identification of TNO155, an Allosteric SHP2 Inhibitor for the Treatment of CancerLaMarche, Matthew J.; Acker, Michael; Argintaru, Andreea; Bauer, Daniel; Boisclair, Julie; Chan, Homan; Chen, Christine Hiu-Tung; Chen, Ying-Nan; Chen, Zhouliang; Deng, Zhan; Dore, Michael; Dunstan, David; Fan, Jianmei; Fekkes, Peter; Firestone, Brant; Fodor, Michelle; Garcia-Fortanet, Jorge; Fortin, Pascal D.; Fridrich, Cary; Giraldes, John; Glick, Meir; Grunenfelder, Denise; Hao, Huia-Xiang; Hentemann, Martin; Ho, Samuel; Jouk, Andriana; Kang, Zhao B.; Karki, Rajesh; Kato, Mitsunori; Keen, Nick; Koenig, Robert; LaBonte, Laura R.; Larrow, Jay; Liu, Gang; Liu, Shumei; Majumdar, Dyuti; Mathieu, Simon; Meyer, Matthew J.; Mohseni, Morvarid; Ntaganda, Rukundo; Palermo, Mark; Perez, Lawrence; Pu, Minying; Ramsey, Timothy; Reilly, John; Sarver, Patrick; Sellers, William R.; Sendzik, Martin; Shultz, Michael D.; Slisz, Joanna; Slocum, Kelly; Smith, Troy; Spence, Stanley; Stams, Travis; Straub, Christopher; Tamez, Victoriano, Jr.; Toure, Bakary-Barry; Towler, Christopher; Wang, Ping; Wang, Hongyun; Williams, Sarah L.; Yang, Fan; Yu, Bing; Zhang, Ji-Hu; Zhu, Suzanne Share Save Share Save Share Save Share Save Distinct Transcriptional Programming Drive Response to MAPK Inhibition in BRAFV600-Mutant Melanoma Patient-Derived XenograftsFeng, Tianshu; Golji, Javad; Li, Ailing; Zhang, Xiamei; Ruddy, David A.; Rakiec, Daniel P.; Geyer, Felipe C.; Gu, Jane; Gao, Hui; Williams, Juliet A.; Stuart, DarrinD.; Meyer, Matthew J. Share Save Tumor Intrinsic Efficacy by SHP2 and RTK Inhibitors in KRAS-Mutant CancersHao, Huai-Xiang; Wang, Hongyun; Liu, Chen; Kovats, Steven; Velazquez, Roberto; Lu, Hengyu; Pant, Bhavesh; Shirley, Matthew; Meyer, Matthew J.; Pu, Minying; Lim, Joanne; Fleming, Michael; Alexander, Leigh Ann; Farsidjani, Ali; LaMarche, Matthew J.; Moody, Susan; Silver, Serena J.; Caponigro, Giordano; Stuart, Darrin D.; Abrams, Tinya J.; Hammerman, Peter S.; Williams, Juliet; Engelman, Jeffrey A.; Goldoni, Silvia; Mohseni, Morvarid Share Save Discovery and characterization of next generation monoclonal antibodies targeting the inhibitory Fc gamma receptor CD32b for the treatment of B and plasma cell malignanciesLu, Haihui; Chen, Dongshu; Jang, Sunyoung; Wolf, Babette; Ewert, Stefan; Flaherty, Meghan; Xu, Fangmin; Isim, Sinan; Shim, Yeonjiu; Dornelas, Christina; Balke, Nicole; Leber, Xavier Charles; Scharenberg, Meike; Koelln, Johanna; Choi, Eugene; Ward, Rebecca; Johnson, Jennifer; Calzascia, Thomas; Isnardi, Isabelle; Williams, Juliet; Huet, Heather; Lees, Emma; Meyer, Matthew J. Share Save Share Save Share Save Share Save Share Save 
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