Not logged in A novel therapeutic antibody screening method using bacterial high-content imaging reveals functional antibody binding phenotypes of Escherichia coli ST131 (vol 10, 12414, 2020) Maes, Mailis; Dyson, Zoe A.; Smith, Sarah E.; Goulding, David A.; Ludden, Catherine; Baker, Stephen; Kellam, Paul; Reece, Stephen T.; Dougan, Gordon; Scott, Josefin Bartholdson Share Save
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A novel therapeutic antibody screening method using bacterial high-content imaging reveals functional antibody binding phenotypes of Escherichia coli ST131 Maes, Mailis; Dyson, Zoe A.; Smith, Sarah E.; Goulding, David A.; Ludden, Catherine; Baker, Stephen; Kellam, Paul; Reece, Stephen T.; Dougan, Gordon; Scott, Josefin Bartholdson Share Save
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Bat IFITM3 restriction depends on S-palmitoylation and a polymorphic site within the CD225 domain Benfield, Camilla T. O.; MacKenzie, Farrell; Ritzefeld, Markus; Mazzon, Michela; Weston, Stuart; Tate, Edward; Teo, Boon Han; Smith, Sarah E.; Kellam, Paul; Holmes, Edward C.; Marsh, Mark Share Save
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3D Printing of Metformin HCl PVA Tablets by Fused Deposition Modeling: Drug Loading, Tablet Design, and Dissolution Studies Ibrahim, Mariam; Barnes, Morgan; McMillin, Robert; Cook, Daniel W.; Smith, Sarah; Halquist, Mathew; Wijesinghe, Dayanjan; Roper, Thomas D. Share Save
Interferon-Induced Transmembrane Protein 1 Restricts Replication of Viruses That Enter Cells via the Plasma Membrane Smith, S. E.; Busse, D. C.; Binter, S.; Weston, S.; Soria, C. Diaz; Laksono, B. M.; Clare, S.; Van Nieuwkoop, S.; Van den Hoogen, B. G.; Clement, M.; Marsden, M.; Humphreys, I. R.; Marsh, M.; de Swart, R. L.; Wash, R. S.; Tregoning, J. S.; Kellam, P. Share Save
Functional analysis of Salmonella Typhi adaptation to survival in water Kingsley, Robert A.; Langridge, Gemma; Smith, Sarah E.; Makendi, Carine; Fookes, Maria; Wileman, Tom M.; Abd El Ghany, Moataz; Turner, A. Keith; Dyson, Zoe A.; Sridhar, Sushmita; Pickard, Derek; Kay, Sally; Feasey, Nicholas; Wong, Vanessa; Barquist, Lars; Dougan, Gordon Share Save
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Investments to reverse biodiversity loss are economically beneficial Sumaila, U. Rashid; Rodriguez, Carlos Manuel; Schultz, Maria; Sharma, Ravi; Tyrrell, Tristan D.; Masundire, Hillary; Damodaran, A.; Bellot-Rojas, Mariana; Rosales, Rina Maria P.; Jung, Tae Yong; Hickey, Valerie; Solhaug, Tone; Vause, James; Ervin, Jamison; Smith, Sarah; Rayment, Matt Share Save
The antiviral restriction factor IFN-induced transmembrane protein 3 prevents cytokine-driven CMV pathogenesis Stacey, Maria A.; Clare, Simon; Clement, Mathew; Marsden, Morgan; Abdul-Karim, Juneid; Kane, Leanne; Harcourt, Katherine; Brandt, Cordelia; Fielding, Ceri A.; Smith, Sarah E.; Wash, Rachael S.; Brias, Silvia Gimeno; Stack, Gabrielle; Notley, George; Cambridge, Emma L.; Isherwood, Christopher; Speak, Anneliese O.; Johnson, Zoe; Ferlin, Walter; Jones, Simon A.; Kellam, Paul; Humphreys, Ian R. Share Save
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Structurally Diverse Mitochondrial Branched Chain Aminotransferase (BCATm) Leads with Varying Binding Modes Identified by Fragment Screening Borthwick, Jennifer A.; Ancellin, Nicolas; Bertrand, Sophie M.; Bingham, Ryan P.; Carter, Paul S.; Chun, Chun-wa; Churcher, Ian; Dodic, Nerina; Fournier, Charlene; Francis, Peter L.; Hobbs, Andrew; Jamieson, Craig; Pickett, Stephen D.; Smith, Sarah E.; Somers, Donald O'N.; Spitzfaden, Claus; Suckling, Colin J.; Young, Robert J. Share Save
Discovery and Optimization of Potent, Selective, and in Vivo Efficacious 2-Aryl Benzimidazole BCATm Inhibitors Deng, Hongfeng; Zhou, Jingye; Sundersingh, Flora; Messer, Jeffrey A.; Somers, Donald O.; Ajakane, Myriam; Arico-Muendel, Christopher C.; Beljean, Arthur; Belyanskaya, Svetlana L.; Bingham, Ryan; Blazensky, Emily; Boullay, Anne-Benedicte; Boursier, Eric; Chai, Jing; Carter, Paul; Chung, Chun-Wa; Daugan, Alain; Ding, Yun; Herry, Kenny; Hobbs, Clare; Humphries, Eric; Kollmann, Christopher; Van Loc Nguyen; Nicodeme, Edwige; Smith, Sarah E.; Dodic, Nerina; Ancellin, Nicolas Share Save
Optimization of Novel Indazoles as Highly Potent and Selective Inhibitors of Phosphoinositide 3-Kinase δ for the Treatment of Respiratory Disease Down, Kenneth; Amour, Augustin; Baldwin, Ian R.; Cooper, Anthony W. J.; Deakin, Angela M.; Felton, Leigh M.; Guntrip, Stephen B.; Hardy, Charlotte; Harrison, Zoe A.; Jones, Katherine L.; Jones, Paul; Keeling, Suzanne E.; Le, Joelle; Livia, Stefano; Lucas, Fiona; Lunniss, Christopher J.; Parr, Nigel J.; Robinson, Ed; Rowland, Paul; Smith, Sarah; Thomas, Daniel A.; Vitulli, Giovanni; Washio, Yoshiaki; Hamblin, J. Nicole Share Save
Discovery, SAR, and X-ray Binding Mode Study of BCATm Inhibitors from a Novel DNA-Encoded Library Deng, Hongfeng; Zhou, Jingye; Sundersingh, Flora S.; Summerfield, Jennifer; Somers, Don; Messer, Jeffrey A.; Satz, Alexander L.; Ancellin, Nicolas; Arico-Muendel, Christopher C.; Bedard, Katie L. (Sargent); Beljean, Arthur; Belyanskaya, Svetlana L.; Bingham, Ryan; Smith, Sarah E.; Boursier, Eric; Carter, Paul; Centrella, Paolo A.; Clark, Matthew A.; Chung, Chun-wa; Davie, Christopher P.; Delorey, Jennifer L.; Ding, Yun; Franklin, G. Joseph; Grady, LaShadric C.; Herry, Kenny; Hobbs, Clare; Kollmann, Christopher S.; Morgan, Barry A.; Kaushansky, Laura J. (Pothier); Zhou, Quan Share Save
The Discovery of in Vivo Active Mitochondrial Branched-Chain Aminotransferase (BCATm) Inhibitors by Hybridizing Fragment and HTS Hits Bertrand, Sophie M.; Ancellin, Nicolas; Beaufils, Benjamin; Bingham, Ryan P.; Borthwick, Jennifer A.; Boullay, Anne-Benedicte; Boursier, Eric; Carter, Paul S.; Chung, Chun-wa; Churcher, Ian; Dodic, Nerina; Fouchet, Marie-Helene; Foumier, Charlene; Francis, Peter L.; Gummer, Laura A.; Herry, Kenny; Hobbs, Andrew; Hobbs, Clare I.; Homes, Paul; Jamieson, Craig; Nicodeme, Edwige; Pickettlt, Stephen D.; Reid, Fain H.; Simpson, Graham L.; Sloan, Lisa A.; Smith, Sarah E.; Somers, Donald O'N.; Spitzfaden, Claus; Suckling, Cohn J.; Valko, Kara; Washio, Yoshiaki; Young, Robert J. Share Save
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