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SavePulmonary delivery of clofoctol-loaded nanoparticles inhibits SARS-CoV-2 replication and reduces pneumonia
Bourguignon, Tom; Godinez-Leon, Jesus Alfredo; Pochet, Amine; Shamsuddin, Tahmida; Sencio, Valentin; Chatagnon, Jonathan; Grande, Axelle; Fine, Joan; Heumel, Severine; Robil, Cyril; Delval, Lou; Piveteau, Catherine; Belouzard, Sandrine; Brodin, Priscille; Trottein, Francois; Machelart, Arnaud; Gref, Ruxandra
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SaveDesign, Synthesis, and Evaluation of Novel Δ2-Thiazolino 2-Pyridone Derivatives That Potentiate Isoniazid Activity in an Isoniazid-Resistant Mycobacterium tuberculosis Mutant
Sarkar, Souvik; Bridwell, Anne Mayer E.; Good, James A. D.; Wang, Erin R.; McKee, Samuel R.; Valenta, Joy; Harrison, Gregory A.; Flentie, Kelly N.; Henry, Frederick L.; Wixe, Torbjorn; Demirel, Peter; Vagolu, Siva K.; Chatagnon, Jonathan; Machelart, Arnaud; Brodin, Priscille; Tonjum, Tone; Stallings, Christina L.; Almqvist, Fredrik
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SaveTirap controls Mycobacterium tuberculosis phagosomal acidification
Belhaouane, Imene; Pochet, Amine; Chatagnon, Jonathan; Hoffmann, Eik; Queval, Christophe J. J.; Deboosere, Nathalie; Boidin-Wichlacz, Celine; Majlessi, Laleh; Sencio, Valentin; Heumel, Severine; Vandeputte, Alexandre; Werkmeister, Elisabeth; Fievez, Laurence; Bureau, Fabrice; Rouille, Yves; Trottein, Francois; Chamaillard, Mathias; Brodin, Priscille; Machelart, Arnaud
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SaveAn Arginine-Rich Motif in the ORF2 capsid protein regulates the hepatitis E virus lifecycle and interactions with the host cell
Hervouet, Kevin; Ferrie, Martin; Ankavay, Maliki; Montpellier, Claire; Camuzet, Charline; Alexandre, Virginie; Dembele, Aicha; Lecoeur, Cecile; Foe, Arnold Thomas; Bouquet, Peggy; Hot, David; Vausselin, Thibaut; Saliou, Jean-Michel; Salome-Desnoulez, Sophie; Vandeputte, Alexandre; Marsollier, Laurent; Brodin, Priscille; Dreux, Marlene; Rouille, Yves; Dubuisson, Jean; Aliouat-Denis, Cecile-Marie; Cocquerel, Laurence
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SaveClofoctol inhibits SARS-CoV-2 replication and reduces lung pathology in mice
Belouzard, Sandrine; Machelart, Arnaud; Sencio, Valentin; Vausselin, Thibaut; Hoffmann, Eik; Deboosere, Nathalie; Rouille, Yves; Desmarets, Lowiese; Seron, Karin; Danneels, Adeline; Robil, Cyril; Belloy, Loic; Moreau, Camille; Piveteau, Catherine; Biela, Alexandre; Vandeputte, Alexandre; Heumel, Severine; Deruyter, Lucie; Dumont, Julie; Leroux, Florence; Engelmann, Ilka; Alidjinou, Enagnon Kazali; Hober, Didier; Brodin, Priscille; Beghyn, Terence; Trottein, Francois; Deprez, Benoit; Dubuisson, Jean
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SaveThe small-molecule SMARt751 reverses Mycobacterium tuberculosis resistance to ethionamide in acute and chronic mouse models of tuberculosis
Flipo, Marion; Frita, Rosangela; Bourotte, Marilyne; Martinez-Martinez, Maria S.; Boesche, Markus; Boyle, Gary W.; Derimanov, Geo; Drewes, Gerard; Gamallo, Pablo; Ghidelli-Disse, Sonja; Gresham, Stephanie; Jimenez, Elena; de Mercado, Jaime; Perez-Herran, Esther; Porras-De Francisco, Esther; Rullas, Joaquin; Casado, Patricia; Leroux, Florence; Piveteau, Catherine; Kiass, Mehdi; Mathys, Vanessa; Soetaert, Karine; Megalizzi, Veronique; Tanina, Abdalkarim; Wintjens, Rene; Antoine, Rudy; Brodin, Priscille; Delorme, Vincent; Moune, Martin; Djaout, Kamel; Slupek, Stephanie; Kemmer, Christian; Gitzinger, Marc; Ballell, Lluis; Mendoza-Losana, Alfonso; Lociuro, Sergio; Deprez, Benoit; Barros-Aguirre, David; Remuinan, Modesto J.; Willand, Nicolas; Baulard, Alain R.
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SaveA combination screening to identify enhancers of para-aminosalicylic acid against Mycobacterium tuberculosis
Heo, Jinyeong; Koh, Dahae; Woo, Minjeong; Kwon, Doyoon; de Almeida Falcao, Virginia Carla; Wood, Connor; Lee, Honggun; Kim, Kideok; Choi, Inhee; Jang, Jichan; Brodin, Priscille; Shum, David; Delorme, Vincent
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SaveThe out-of-field dose in radiation therapy induces delayed tumorigenesis by senescence evasion
Goy, Erwan; Tomezak, Maxime; Facchin, Caterina; Martin, Nathalie; Bouchaert, Emmanuel; Benoit, Jerome; de Schutter, Clementine; Nassour, Joe; Saas, Laure; Drullion, Claire; Brodin, Priscille M.; Vandeputte, Alexandre; Molendi-Coste, Olivier; Pineau, Laurent; Goormachtigh, Gautier; Pluquet, Olivier; Pourtier, Albin; Cleri, Fabrizio; Lartigau, Eric; Penel, Nicolas; Abbadie, Corinne
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SaveAlteration of the gut microbiota following SARS-CoV-2 infection correlates with disease severity in hamsters
Sencio, Valentin; Machelart, Arnaud; Robil, Cyril; Benech, Nicolas; Hoffmann, Eik; Galbert, Chloe; Deryuter, Lucie; Heumel, Severine; Hantute-Ghesquier, Aline; Flourens, Anne; Brodin, Priscille; Infanti, Fabrice; Richard, Virgile; Dubuisson, Jean; Grangette, Corinne; Sulpice, Thierry; Wolowczuk, Isabelle; Pinet, Florence; Prevot, Vincent; Belouzard, Sandrine; Briand, Francois; Duterque-Coquillaud, Martine; Sokol, Harry; Trottein, Francois
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SaveAconitate decarboxylase 1 participates in the control of pulmonary Brucella infection in mice
Demars, Aurore; Vitali, Armelle; Comein, Audrey; Carlier, Elodie; Azouz, Abdulkader; Goriely, Stanislas; Smout, Justine; Flamand, Veronique; Van Gysel, Megane; Wouters, Johan; Abendroth, Jan; Edwards, Thomas E.; Machelart, Arnaud; Hoffmann, Eik; Brodin, Priscille; De Bolle, Xavier; Muraille, Eric
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SavePathogenomic analyses of Mycobacterium microti, an ESX-1-deleted member of the Mycobacterium tuberculosis complex causing disease in various hosts
Orgeur, Mickael; Frigui, Wafa; Pawlik, Alexandre; Clark, Simon; Williams, Ann; Ates, Louis S.; Ma, Laurence; Bouchier, Christiane; Parkhill, Julian; Brodin, Priscille; Brosch, Roland
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