logo
CanyamAI summaries for academic research
language
MobileMobile
  • Phone FeatureWeChat Mini Program
EnglishEnglish
noticeNotice
BlogBlog
delete
arrow
Back
T

T.L. Poulos

University of California

86H-index
681Paper Count
3.1WCitation Count
Published Papers 154
Publication Date
logo
An assessment of the cytochrome P450 2-hydroxyisoflavanone synthase (2-HIS) crystal structure
errCommunications Biology
IF5.1
err2026-05-26
err0
errOAAI
errThomas L. Poulos
errShare
errSave
Enhancement of Potency and Selectivity of 2-Aminoquinoline-Based Human Neuronal Nitric Oxide Synthase Inhibitors
errJournal of Medicinal Chemistry
IF6.8
err2026-02-04
err0
PREAI
errAnas Ansari; Koon Mook Kang; Huiying Li; Christine D. Hardy; Athri D. Rathnayake; Amardeep Awasthi; Thomas L. Poulos; Richard B. Silverman
errShare
errSave
Potent; Selective; and Brain Penetrant Ether-Linked 2-Aminopyridine Inhibitors of Human Neuronal Nitric Oxide Synthase with Excellent Oral Bioavailability
errJournal of Medicinal Chemistry
IF6.8
err2026-02-02
err0
PREAI
errAnas Ansari; Radoslaw T. Chrzanowski; Huiying Li; Christine D. Hardy; Amardeep Awasthi; Thomas L. Poulos; Richard B. Silverman
errShare
errSave
New Inhibitors of Neuronal Nitric Oxide Synthase for the Treatment of Melanoma
errJournal of Medicinal Chemistry
IF6.8
err2026-01-30
err0
errOAAI
errAmardeep Awasthi; Anika Patel; Huiying Li; Koon Mook Kang; Christine D. Hardy; Anas Ansari; Raghad Nowar; Md. Emtiaz Hasan; Sun Yang; Thomas L. Poulos; Richard B. Silverman
errShare
errSave
Redox Partner Recognition and Selectivity of Cytochrome P450terp (CYP108A1)
errBIOCHEMISTRY
IF3
err2025-12-01
err0
PREAI
errGable, Jessica A.; Poulos, Thomas L.; Follmer, Alec H.
errShare
errSave
Truncated pyridinylbenzylamines: Potent, selective, and highly membrane permeable inhibitors of human neuronal nitric oxide synthase
errBIOORGANIC & MEDICINAL CHEMISTRY
IF3
err2025-07-01
err0
PREAI
errVasu, Dhananjayan; Do, Ha T.; Li, Huiying; Hardy, Christine D.; Poulos, Thomas L.; Silverman, Richard B.
errShare
errSave
A Tetrahydrobiopterin-Displacing Potent Neuronal Nitric Oxide Synthase Inhibitor with an Unprecedented Binding Mode
errACS MEDICINAL CHEMISTRY LETTERS
IF4
err2025-03-01
err0
PREAI
errWeerawarna, Pathum M.; Li, Huiying; Rathnayake, Athri D.; Hardy, Christine D.; Poulos, Thomas L.; Silverman, Richard B.
errShare
errSave
Crystal structure of cytochrome P450 NysL and the structural basis for stereo- and regio-selective oxidation of antifungal macrolides
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2025-03-01
err0
errOAAI
errMurarka, Vidhi C.; Kim, Jenny S.; Lamb, David C.; Kelly, Steven L.; Poulos, Thomas L.; Follmer, Alec H.
errShare
errSave
Application of the Linear Interaction Energy Method to Nitric Oxide Synthase Structure-Based Inhibitor Design
errJOURNAL OF CHEMICAL INFORMATION AND MODELING
IF5.3
err2024-11-07
err1
PREAI
errFollmer, Alec H.; Poulos, Thomas L.
errShare
errSave
Potent, Selective, and Membrane Permeable 2-Amino-4-Substituted Pyridine-Based Neuronal Nitric Oxide Synthase Inhibitors
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2023-07-11
err5
PREAI
errVasu, Dhananjayan; Do, Ha T. T.; Li, Huiying; Hardy, Christine D. D.; Awasthi, Amardeep; Poulos, Thomas L. L.; Silverman, Richard B. B.
errShare
errSave
Redox partner recognition and selectivity of cytochrome P450lin (CYP111A1)
errJOURNAL OF INORGANIC BIOCHEMISTRY
IF3.2
err2023-07-01
err1
errOAAI
errGable, Jessica A.; Poulos, Thomas L.; Follmer, Alec H.
errShare
errSave
Predicting the environmental fates of emerging contaminants: Synergistic effects in ozone reactions of nitrogen-containing alkenes
errSCIENCE ADVANCES
IF12.5
err2023-03-03
err8
errOAAI
errWang, Xinke; Wang, Weihong; Wingen, Lisa M.; Perraud, Veronique; Ezell, Michael J.; Gable, Jessica; Poulos, Thomas L.; Finlayson-Pitts, Barbara J.
errShare
errSave
Cooperative Substrate Binding Controls Catalysis in Bacterial Cytochrome P450terp (CYP108A1)
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2023-02-13
err7
PREAI
errGable, Jessica A.; Poulos, Thomas L.; Follmer, Alec H.
errShare
errSave
2-Aminopyridines with a shortened amino sidechain as potent, selective, and highly permeable human neuronal nitric oxide synthase inhibitors
errBIOORGANIC & MEDICINAL CHEMISTRY
IF3
err2022-09-01
err11
errOAAI
errVasu, Dhananjayan; Li, Huiying; Hardy, Christine D.; Poulos, Thomas L.; Silverman, Richard B.
errShare
errSave
Structural Insights on the Conversion of Cytochrome P450 to P420
errACS OMEGA
IF4.3
err2022-05-27
err7
errOAAI
errGable, Jessica A.; Tripathi, Sarvind; Poulos, Thomas L.
errShare
errSave
Structural analysis of P450 AmphL from Streptomyces nodosus provides insights into substrate selectivity of polyene macrolide antibiotic biosynthetic P450s
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2022-04-01
err3
errOAAI
errAmaya, Jose A.; Lamb, David C.; Kelly, Steven L.; Caffrey, Patrick; Murarka, Vidhi C.; Poulos, Thomas L.
errShare
errSave
Updating the Paradigm: Redox Partner Binding and Conformational Dynamics in Cytochromes P450
errACCOUNTS OF CHEMICAL RESEARCH
IF17.7
err2021-12-29
err28
errOAAI
errPoulos, Thomas L.; Follmer, Alec H.
errShare
errSave
First Contact: 7-Phenyl-2-Aminoquinolines, Potent and Selective Neuronal Nitric Oxide Synthase Inhibitors That Target an Isoform-Specific Aspartate
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2020-04-17
err19
errOAAI
errCinelli, Maris A.; Reidl, Cory T.; Li, Huiying; Chreifi, Georges; Poulos, Thomas L.; Silverman, Richard B.
errShare
errSave
On the occurrence of cytochrome P450 in viruses
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2019-06-05
err53
errOAAI
errLamb, David C.; Follmer, Alec H.; Goldstone, Jared V.; Nelson, David R.; Warrilow, Andrew G.; Price, Claire L.; True, Marie Y.; Kelly, Steven L.; Poulos, Thomas L.; Stegeman, John J.
errShare
errSave
Optimization of Blood-Brain Barrier Permeability with Potent and Selective Human Neuronal Nitric Oxide Synthase Inhibitors Having a 2-Aminopyridine Scaffold
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2019-02-25
err33
errOAAI
errDo, Ha T.; Li, Huiying; Chreifi, Georges; Poulos, Thomas L.; Silverman, Richard B.
errShare
errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
M
Mark H. Ellisman
H-index: 126 · Papers: 769
J
John R. Falck
H-index: 120 · Papers: 1.2K
V
Vamsi K. Mootha
H-index: 109 · Papers: 367
刘
刘艺 (Yi Liu)
H-index: 107 · Papers: 1.7K
N
Neil L. Kelleher
H-index: 106 · Papers: 712
View more