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H

Hugo Gutiérrez‐de‐Terán

Uppsala University

34H指数
145论文数
3.2K被引数
收录论文 70
发表时间
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New high affinity AT2 receptor ligands comprising a 2-methyl substituted phenylthiophene scaffold新型高亲和力AT2受体配体，包含2-甲基取代的苯并噻吩骨架
errBIOORGANIC & MEDICINAL CHEMISTRY
IF3
err2026-09-01
err0
PREAI
errGising, Johan; Wannberg, Johan; Isaksson, Rebecka; Sallander, Jessica; Gutierrez-de-Teran, Hugo; Backlund, Maria; Hallberg, Mathias; Larhed, Mats
err分享
err收藏
Doing More with Less: Accurate and Scalable Ligand Free Energy Calculations by Focusing on the Binding Site以少胜多：通过聚焦结合位点实现准确且可扩展的配体自由能计算
errJournal of Chemical Information and Modeling
IF5.3
err2026-02-13
err0
errOAAI
errDavid Alencar Araripe; Alejandro Díaz-Holguín; Antti Poso; Gerard J. P. van Westen; Johan Åqvist; Hugo Gutiérrez-de-Terán; Willem Jespers
err分享
err收藏
Accurate predictions of protein mutational effects accelerated with a hybrid-topology free energy protocol基于混合拓扑自由能协议加速的蛋白质突变效应准确预测
errCommunications Chemistry
IF6.2
err2025-11-20
err0
errOAAI
errLucien Koenekoop; Nadine van de Brug; Willem Jespers; Johan Åqvist; Hugo Gutiérrez-de-Terán
err分享
err收藏
Ligand and Residue Free Energy Perturbations Solve the Dual Binding Mode Proposal for an A2BAR Partial Agonist配体和残基自由能扰动解决了A2BAR部分激动剂的双结合模式提议
errJOURNAL OF PHYSICAL CHEMISTRY B
IF2.9
err2025-01-08
err0
errOAAI
errTandaric, Tana; Gutierrez-de-Teran, Hugo
err分享
err收藏
Benzylhydroxamic acids as inhibitors of insulin regulated aminopeptidase (IRAP)
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY REPORTS
IF4.1
err2024-12-01
err1
errOAAI
errBeveridge, Julia; Soderstrom, Marcus; Prieto-Diaz, Ruben; Gutierrez-de-Teran, Hugo; Odell, Luke R.; Hallberg, Mathias; Larhed, Mats; Gising, Johan
err分享
err收藏
Interaction networks within disease-associated GaS variants characterized by an integrative biophysical approach
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2024-08-01
err0
errOAAI
errAnazia, Kara; Koenekoop, Lucien; Ferre, Guillaume; Petracco, Enzo; Gutierrez-de-Teran, Hugo; Eddy, Matthew T.
err分享
err收藏
Exploring Biginelli-based scaffolds as A2B adenosine receptor antagonists: Unveiling novel structure-activity relationship trends, lead compounds, and potent colorectal anticancer agents
errBIOMEDICINE & PHARMACOTHERAPY
IF7.5
err2024-04-01
err0
errOAAI
errPrieto-Diaz, Ruben; Fojo-Carballo, Hugo; Majellaro, Maria; Tandaric, Tana; Azuaje, Jhonny; Brea, Jose; Loza, Maria I.; Barbazan, Jorge; Salort, Gloria; Chotalia, Meera; Rodriguez-Pampin, Ivan; Mallo-Abreu, Ana; Paleo, M. Rita; Garcia-Mera, Xerardo; Ciruela, Francisco; Gutierrez-de-Teran, Hugo; Sotelo, Eddy
err分享
err收藏
N-(Heteroaryl)thiophene sulfonamides as angiotensin AT2 receptor ligands
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2024-02-01
err1
errOAAI
errWannberg, Johan; Gising, Johan; Henriksson, Martin; Vo, Duc Duy; Savmarker, Jonas; Sallander, Jessica; Gutierrez-de-Teran, Hugo; Larsson, Johanna; Hamid, Selin; Ablahad, Hanin; Spizzo, Iresha; Gaspari, Tracey A.; Widdop, Robert E.; Gronbladh, Alfhild; Petersen, Nadia N.; Backlund, Maria; Hallberg, Mathias; Larhed, Mats
err分享
err收藏
Exploring the Effect of Halogenation in a Series of Potent and Selective A2B Adenosine Receptor Antagonists
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2022-12-14
err11
errOAAI
errPrieto-Diaz, Ruben; Gonzalez-Gomez, Manuel; Fojo-Carballo, Hugo; Azuaje, Jhonny; El Maatougui, Abdelaziz; Majellaro, Maria; Loza, Maria, I; Brea, Jose; Fernandez-Duenas, Victor; Paleo, M. Rita; Diaz-Holguin, Alejandro; Garcia-Pinel, Beatriz; Mallo-Abreu, Ana; Estevez, Juan C.; Andujar-Arias, Antonio; Garcia-Mera, Xerardo; Gomez-Tourino, Iria; Ciruela, Francisco; Salas, Cristian O.; Gutierrez-de-Teran, Hugo; Sotelo, Eddy
err分享
err收藏
Pan-cancer functional analysis of somatic mutations in G protein-coupled receptors
errSCIENTIFIC REPORTS
IF3.9
err2022-12-13
err9
errOAAI
errBongers, B. J.; Gonzalez, M. Gorostiola; Wang, X.; van Vlijmen, H. W. T.; Jespers, W.; Gutierrez-de-Teran, H.; Ye, K.; IJzerman, A. P.; Heitman, L. H.; van Westen, G. J. P.
err分享
err收藏
Optimization of 2-Amino-4,6-diarylpyrimidine-5-carbonitriles as Potent and Selective A1 Antagonists
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2022-01-22
err6
errOAAI
errVal, Cristina; Rodriguez-Garcia, Carlos; Prieto-Diaz, Ruben; Crespo, Abel; Azuaje, Jhonny; Carbajales, Carlos; Majellaro, Maria; Diaz-Holguin, Alejandro; Brea, Jose M.; Isabel Loza, Maria; Gioe-Gallo, Claudia; Contino, Marialessandra; Stefanachi, Angela; Garcia-Mera, Xerardo; Estevez, Juan C.; Gutierrez-de-Teran, Hugo; Sotelo, Eddy
err分享
err收藏
Exploring Non-orthosteric Interactions with a Series of Potent and Selective A3 Antagonists
errACS MEDICINAL CHEMISTRY LETTERS
IF4
err2022-01-10
err2
errOAAI
errMiranda-Pastoriza, Dario; Bernardez, Rodrigo; Azuaje, Jhonny; Prieto-Diaz, Ruben; Majellaro, Maria; Tamhankar, Ashish, V; Koenekoop, Lucien; Gonzalez, Alejandro; Gioe-Gallo, Claudia; Mallo-Abreu, Ana; Brea, Jose; Isabel Loza, M.; Garcia-Rey, Aitor; Garcia-Mera, Xerardo; Gutierrez-de-Teran, Hugo; Sotelo, Eddy
err分享
err收藏
Potent Inhibition of Nicotinamide N-Methyltransferase by Alkene-Linked Bisubstrate Mimics Bearing Electron Deficient Aromatics
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2021-08-23
err48
errOAAI
errGao, Yongzhi; van Haren, Matthijs J.; Buijs, Ned; Innocenti, Paolo; Zhang, Yurui; Sartini, Davide; Campagna, Roberto; Emanuelli, Monica; Parsons, Richard B.; Jespers, Willem; Gutierrez-de-Teran, Hugo; van Westen, Gerard J. P.; Martin, Nathaniel, I
err分享
err收藏
Design, synthesis, HER2 inhibition and anticancer evaluation of new substituted 1,5-dihydro-4,1-benzoxazepines
errJOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
IF5.4
err2021-07-12
err6
errOAAI
errCruz-Lopez, Olga; Ner, Matilde; Nerin-Fonz, Francho; Jimenez-Martinez, Yaiza; Araripe, David; Marchal, Juan A.; Boulaiz, Houria; Gutierrez-de-Teran, Hugo; Campos, Joaquin M.; Conejo-Garcia, Ana
err分享
err收藏
Identification of V6.51L as a selectivity hotspot in stereoselective A2B adenosine receptor antagonist recognition
errSCIENTIFIC REPORTS
IF3.9
err2021-07-08
err8
errOAAI
errWang, Xuesong; Jespers, Willem; Prieto-Diaz, Ruben; Majellaro, Maria; IJzerman, Adriaan P.; van Westen, Gerard J. P.; Sotelo, Eddy; Heitman, Laura H.; Gutierrez-de-Teran, Hugo
err分享
err收藏
Potent and Subtype-Selective Dopamine D2 Receptor Biased Partial Agonists Discovered via an Ugi-Based Approach
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2021-06-10
err6
errOAAI
errMallo-Abreu, Ana; Reyes-Resina, Irene; Azuaje, Jhonny; Franco, Rafael; Garcia-Rey, Aitor; Majellaro, Maria; Miranda-Pastoriza, Dario; Garcia-Mera, Xerardo; Jespers, Willem; Gutierrez-de-Teran, Hugo; Navarro, Gemma; Sotelo, Eddy
err分享
err收藏
Editorial: Physiological, Pathological Roles and Pharmacology of Insulin Regulated Aminopeptidase
errFRONTIERS IN MOLECULAR BIOSCIENCES
IF4
err2021-04-23
err0
errOAAI
errChai, Siew Yeen; Gutierrez-de-Teran, Hugo; Stratikos, Efstratios
err分享
err收藏
Structural Basis of Inhibition of Human Insulin-Regulated Aminopeptidase (IRAP) by Benzopyran-Based Inhibitors
errFRONTIERS IN MOLECULAR BIOSCIENCES
IF4
err2021-04-01
err4
errOAAI
errVanga, Sudarsana Reddy; Aqvist, Johan; Hallberg, Anders; Gutierrez-de-Teran, Hugo
err分享
err收藏
N-(Methyloxycarbonyl)thiophene sulfonamides as high affinity AT2 receptor ligands
errBIOORGANIC & MEDICINAL CHEMISTRY
IF3
err2021-01-01
err7
PREAI
errWannberg, Johan; Gising, Johan; Lindman, Jens; Salander, Jessica; Gutierrez-de-Teran, Hugo; Ablahad, Hanin; Hamid, Selin; Gronbladh, Alfhild; Spizzo, Iresha; Gaspari, Tracey A.; Widdop, Robert E.; Hallberg, Anders; Backlund, Maria; Lesniak, Anna; Hallberg, Mathias; Larhed, Mats
err分享
err收藏
3,4-Dihydropyrimidin-2(1H)-ones as Antagonists of the Human A2B Adenosine Receptor: Optimization, Structure-Activity Relationship Studies, and Enantiospecific Recognition
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2020-12-29
err21
PREAI
errMajellaro, Maria; Jespers, Willem; Crespo, Abel; Nunez, Maria J.; Novio, Silvia; Azuaje, Jhonny; Prieto-Diaz, Ruben; Gioe, Claudia; Alispahic, Belma; Brea, Jose; Loza, Maria, I; Freire-Garabal, Manuel; Garcia-Santiago, Carlota; Rodriguez-Garcia, Carlos; Garcia-Mera, Xerardo; Caamano, Olga; Fernandez-Masaguer, Christian; Sardina, Javier F.; Stefanachi, Angela; El Maatougui, Abdelaziz; Mallo-Abreu, Ana; Aqvist, Johan; Gutierrez-de-Teran, Hugo; Sotelo, Eddy
err分享
err收藏

研究方向

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