Michael A. Lodato - Publications, H-index & Citations

Michael A. Lodato

Harvard University

27H指数

65论文数

8.8K被引数

收录论文 19

发表时间

Combined somatic mutation and transcriptome analysis reveals region-specific differences in clonal architecture in human cortex 结合体细胞突变和转录组分析揭示了人类大脑皮层中克隆结构存在区域特异性差异。

Cell Reports

IF6.9

2025-11-14

OAAI

Vinayak V. Viswanadham; Sonia N. Kim; Emre Caglayan; Ryan N. Doan; Yanmei Dou; Sara Bizzotto; Sattar Khoshkhoo; August Yue Huang; Rebecca Yeh; Brian H. Chhouk; Alex Truong; Kathleen M. Chappell; Marc Beaudin; Alison Barton; Shyam K. Akula; Yifan Zhao; Lariza Rento; Michael Lodato; Ryan A. Szeto; Javier Ganz

ATM-deficiency-induced microglial activation promotes neurodegeneration in ataxia-telangiectasia

CELL REPORTS

IF6.9

2024-01-01

OAAI

Lai, Jenny; Demirbas, Didem; Kim, Junho; Jeffries, Ailsa M.; Tolles, Allie; Park, Junseok; Chittenden, Thomas W.; Buckley, Patrick G.; Yu, Timothy W.; Lodato, Michael A.; Lee, Eunjung Alice

Somatic mutations, genome mosaicism and aging 体细胞突变，基因组镶嵌和衰老

FRONTIERS IN AGING

IF4.3

2023-01-09

OAAI

Lodato, Michael A.; Vijg, Jan

The two faces of DNA oxidation in genomic and functional mosaicism during aging in human neurons

FRONTIERS IN AGING

IF4.3

2022-10-12

OAAI

Lodato, Michael A.; Ziegenfuss, Jennifer S.

Prevalence and mechanisms of somatic deletions in single human neurons during normal aging and in DNA repair disorders

NATURE COMMUNICATIONS

IF15.7

2022-10-07

OAAI

Kim, Junho; Huang, August Yue; Johnson, Shelby L.; Lai, Jenny; Isacco, Laura; Jeffries, Ailsa M.; Miller, Michael B.; Lodato, Michael A.; Walsh, Christopher A.; Lee, Eunjung Alice

Single-cell genome sequencing of human neurons identifies somatic point mutation and indel enrichment in regulatory elements

NATURE GENETICS

IF31.8

2022-09-26

OAAI

Luquette, Lovelace J.; Miller, Michael B.; Zhou, Zinan; Bohrson, Craig L.; Zhao, Yifan; Jin, Hu; Gulhan, Doga; Ganz, Javier; Bizzotto, Sara; Kirkham, Samantha; Hochepied, Tino; Libert, Claude; Galor, Alon; Kim, Junho; Lodato, Michael A.; Garaycoechea, Juan, I; Gawad, Charles; West, Jay; Walsh, Christopher A.; Park, Peter J.

Somatic mutations in single human cardiomyocytes reveal age-associated DNA damage and widespread oxidative genotoxicity

NATURE AGING

IF19.4

2022-08-11

OAAI

Choudhury, Sangita; Huang, August Yue; Kim, Junho; Zhou, Zinan; Morino, Katherine; Maury, Eduardo A.; Tsai, Jessica W.; Miller, Michael B.; Lodato, Michael A.; Araten, Sarah; Hilal, Nazia; Lee, Eunjung Alice; Chen, Ming Hui; Walsh, Christopher A.

Persistent DNA damage associated with ATM kinase deficiency promotes microglial dysfunction

NUCLEIC ACIDS RESEARCH

IF13.1

2022-02-25

OAAI

Bourseguin, Julie; Cheng, Wen; Talbot, Emily; Hardy, Liana; Lai, Jenny; Jeffries, Ailsa M.; Lodato, Michael A.; Lee, Eunjung Alice; Khoronenkova, Svetlana, V

Genome aging: somatic mutation in the brain links age-related decline with disease and nominates pathogenic mechanisms (vol 28, pg R197, 2019)

HUMAN MOLECULAR GENETICS

IF3.2

2019-11-28

OAAI

Lodato, Michael A.; Walsh, Christopher A.

Genome aging: somatic mutation in the brain links age-related decline with disease and nominates pathogenic mechanisms

HUMAN MOLECULAR GENETICS

IF3.2

2019-09-06

OAAI

Lodato, Michael A.; Walsh, Christopher A.

Linked-read analysis identifies mutations in single-cell DNA-sequencing data

NATURE GENETICS

IF31.8

2019-03-18

OAAI

Bohrson, Craig L.; Barton, Alison R.; Lodato, Michael A.; Rodin, Rachel E.; Luquette, Lovelace J.; Viswanadham, Vinay V.; Gulhan, Doga C.; Cortes-Ciriano, Isidro; Sherman, Maxwell A.; Kwon, Minseok; Coulter, Michael E.; Galor, Alon; Walsh, Christopher A.; Park, Peter J.

PaSD-qc: quality control for single cell whole-genome sequencing data using power spectral density estimation

NUCLEIC ACIDS RESEARCH

IF13.1

2017-11-25

OAAI

Sherman, Maxwell A.; Barton, Alison R.; Lodato, Michael A.; Vitzthum, Carl; Coulter, Michael E.; Walsh, Christopher A.; Park, Peter J.

SOX2 Co-Occupies Distal Enhancer Elements with Distinct POU Factors in ESCs and NPCs to Specify Cell State

PLOS GENETICS

IF3.7

2013-02-21

171

OAAI

Lodato, Michael A.; Ng, Christopher W.; Wamstad, Joseph A.; Cheng, Albert W.; Thai, Kevin K.; Fraenkel, Ernest; Jaenisch, Rudolf; Boyer, Laurie A.

Functional Integration of Dopaminergic Neurons Directly Converted from Mouse Fibroblasts

CELL STEM CELL

IF20.4

2011-11-01

237

OAAI

Kim, Jongpil; Su, Susan C.; Wang, Haoyi; Cheng, Albert W.; Cassady, John P.; Lodato, Michael A.; Lengner, Christopher J.; Chung, Chee-Yeun; Dawlaty, Meelad M.; Tsai, Li-Huei; Jaenisch, Rudolf

Predicting professional preferences for intuition-based hiring

JOURNAL OF MANAGERIAL PSYCHOLOGY

IF2.7

2011-07-05

PREAI

Lodato, Michael A.; Highhouse, Scott; Brooks, Margaret E.

Reprogramming of Postnatal Neurons into Induced Pluripotent Stem Cells by Defined Factors 通过定义的因子将出生后神经元重编程为诱导性多能干细胞

Stem Cells

IF3.6

2011-05-23

OAAI

Kim, Jongpil; Lengner, Christopher J.; Kirak, Oktay; Hanna, Jacob; Cassady, John P.; Lodato, Michael A.; Wu, Su; Faddah, Dina A.; Steine, Eveline J.; Gao, Qing; Fu, Dongdong; Dawlaty, Meelad; Jaenisch, Rudolf

Histone H3K27ac separates active from poised enhancers and predicts developmental state

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2010-11-24

3.5K

OAAI

Creyghton, Menno P.; Cheng, Albert W.; Welstead, G. Grant; Kooistra, Tristan; Carey, Bryce W.; Steine, Eveline J.; Hanna, Jacob; Lodato, Michael A.; Frampton, Garrett M.; Sharp, Phillip A.; Boyer, Laurie A.; Young, Richard A.; Jaenisch, Rudolf

A drug-inducible transgenic system for direct reprogramming of multiple somatic cell types

NATURE BIOTECHNOLOGY

IF41.7

2008-07-01

462

OAAI

Wernig, Marius; Lengner, Christopher J.; Hanna, Jacob; Lodato, Michael A.; Steine, Eveline; Foreman, Ruth; Staerk, Judith; Markoulaki, Styliani; Jaenisch, Rudolf

Understanding the training needs of department chairs

STUDIES IN HIGHER EDUCATION

IF3.2

2005-10-01

PREAI

Aziz, S; Mullins, ME; Balzer, WK; Grauer, E; Burnfield, JL; Lodato, MA; Cohen-Powless, MA

研究方向