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C

Christiaan Klijn

roche holding usa
H指数:29
被引数:4,568

个人简介

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工作经历

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荣誉奖项

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CRAF dimerization with ARAF regulates KRAS-driven tumor growth
CELL REPORTS
IF6.9
2022-02-0119
OA
Venkatanarayan, Avinashnarayan; Liang, Jason; Yen, Ivana; Shanahan, Frances; Haley, Benjamin; Phu, Lilian; Verschueren, Erik; Hinkle, Trent B.; Kan, David; Segal, Ehud; Long, Jason E.; Lima, Tony; Liau, Nicholas P. D.; Sudhamsu, Jawahar; Li, Jason; Klijn, Christiaan; Piskol, Robert; Junttila, Melissa R.; Shaw, Andrey S.; Merchant, Mark; Chang, Matthew T.; Kirkpatrick, Donald S.; Malek, Shiva
Single-Cell RNA Sequencing Reveals Stromal Evolution into LRRC15+ Myofibroblasts as a Determinant of Patient Response to Cancer Immunotherapy

单细胞RNA测序揭示基质向LRRC15肌成纤维细胞的进化是患者对癌症免疫疗法反应的决定因素

CANCER DISCOVERY
IF33.3
2020-02-05515
OAAI
Dominguez, Claudia X.; Mueller, Soren; Keerthivasan, Shilpa; Koeppen, Hartmut; Hung, Jeffrey; Gierke, Sarah; Breart, Beatrice; Foreman, Oded; Bainbridge, Travis W.; Castiglioni, Alessandra; Senbabaoglu, Yasin; Modrusan, Zora; Liang, Yuxin; Junttila, Melissa R.; Klijn, Christiaan; Bourgon, Richard; Turley, Shannon J.
The Hippo pathway effector TAZ induces TEAD-dependent liver inflammation and tumors
SCIENCE SIGNALING
IF6.6
2018-09-1170
OAAI
Hagenbeek, Thijs J.; Webster, Joshua D.; Kljavin, Noelyn M.; Chang, Matthew T.; Trang Pham; Lee, Ho-June; Klijn, Christiaan; Cai, Allen G.; Totpal, Klara; Ravishankar, Buvana; Yang, Naiying; Lee, Da-Hye; Walsh, Kevin B.; Hatzivassiliou, Georgia; de la Cruz, Cecile C.; Gould, Stephen E.; Wu, Xiumin; Lee, Wyne P.; Yang, Shuqun; Zhang, Zhixiang; Gu, Qingyang; Ji, Qunsheng; Jackson, Erica L.; Lim, Dae-Sik; Dey, Anwesha
Development and mechanistic characterization of USP7 deubiquitinase inhibitors
CANCER RESEARCH
IF16.6
2018-07-010
PRE
Wertz, Ingrid; Kategaya, Lorna; Di Lello, Paola; Rouge, Lionel; Pastor, Richard; Clark, Kevin R.; Drummond, Jason; Kleinheinz, Tracy; Lin, Eva; Upton, John-Paul; Prakash, Sumit; Heideker, Johanna; McCleland, Mark; Ritorto, Maria Stella; Alessi, Dario R.; Trost, Matthias; Bainbridge, Travis W.; Kwok, Michael C.; Ma, Taylur P.; Stiffler, Zachary; Brasher, Bradley; Tang, Yinyan; Jaishanker, Priya; Hearn, Brian; Renslo, Adam R.; Arkin, Michelle R.; Cohen, Frederick; Yu, Kebing; Peale, Frank; Gnad, Florian; Chang, Matthew T.; Klijn, Christiaan; Blackwood, Elizabeth; Martin, Scott E.; Forrest, William F.; Ernst, James A.; Ndubaku, Chudi; Wang, Xiaojing; Beresini, Maureen H.; Tsui, Vickie; Schwerdtfeger, Carsten; Blake, Robert A.; Murray, Jeremy; Maurer, Till
A transcriptional MAPK Pathway Activity Score (MPAS) is a clinically relevant biomarker in multiple cancer types
NPJ PRECISION ONCOLOGY
IF8
2018-03-07119
OAAI
Wagle, Marie-Claire; Kirouac, Daniel; Klijn, Christiaan; Liu, Bonnie; Mahajan, Shilpi; Junttila, Melissa; Moffat, John; Merchant, Mark; Huw, Ling; Wongchenko, Matthew; Okrah, Kwame; Srinivasan, Shrividhya; Mounir, Zineb; Sumiyoshi, Teiko; Haverty, Peter M.; Yauch, Robert L.; Yan, Yibing; Kabbarah, Omar; Hampton, Garret; Amler, Lukas; Ramanujan, Saroja; Lackner, Mark R.; Huang, Shih-Min A.
BRCA1185delAG tumors may acquire therapy resistance through expression of RING-less BRCA1
JOURNAL OF CLINICAL INVESTIGATION
IF13.6
2016-07-25121
OA
Drost, Rinske; Dhillon, Kiranjit K.; van der Gulden, Hanneke; van der Heijden, Ingrid; Brandsma, Inger; Cruz, Cristina; Chondronasiou, Dafni; Castroviejo-Bermejo, Marta; Boon, Ute; Schut, Eva; van der Burg, Eline; Wientjens, Ellen; Pieterse, Mark; Klijn, Christiaan; Klarenbeek, Sjoerd; Loayza-Puch, Fabricio; Elkon, Ran; van Deemter, Liesbeth; Rottenberg, Sven; van de Ven, Marieke; Dekkers, Dick H. W.; Demmers, Jeroen A. A.; van Gent, Dik C.; Agami, Reuven; Balmana, Judith; Serra, Violeta; Taniguchi, Toshiyasu; Bouwman, Peter; Jonkers, Jos
A comprehensive transcriptional portrait of human cancer cell lines

人类癌细胞系的全面转录肖像

NATURE BIOTECHNOLOGY
IF41.7
2014-12-08535
PREAI
Klijn, Christiaan; Durinck, Steffen; Stawiski, Eric W.; Haverty, Peter M.; Jiang, Zhaoshi; Liu, Hanbin; Degenhardt, Jeremiah; Mayba, Oleg; Gnad, Florian; Liu, Jinfeng; Pau, Gregoire; Reeder, Jens; Cao, Yi; Mukhyala, Kiran; Selvaraj, Suresh K.; Yu, Mamie; Zynda, Gregory J.; Brauer, Matthew J.; Wu, Thomas D.; Gentleman, Robert C.; Manning, Gerard; Yauch, Robert L.; Bourgon, Richard; Stokoe, David; Modrusan, Zora; Neve, Richard M.; de Sauvage, Frederic J.; Settleman, Jeffrey; Seshagiri, Somasekar; Zhang, Zemin

研究方向

暂未获取到该数据
J
Jos Jonkers
H 指数:0论文数:5被引数:0
L
Lodewyk F.A. Wessels
H 指数:89论文数:1,030被引数:4.7万
M
Mark Merchant
H 指数:48论文数:380被引数:1.0万
F
Florian Gnad
H 指数:48论文数:144被引数:2.1万
S
Sjoerd Klarenbeek
H 指数:22论文数:167被引数:1,942
Z
Zora Modrušan
H 指数:102论文数:591被引数:4.3万
D
David J. Adams
H 指数:113论文数:975被引数:5.7万
S
Shiva Malek
H 指数:36论文数:216被引数:7,389
S
Somasekar Seshagiri
H 指数:67论文数:255被引数:2.6万
S
Scott E. Martin
H 指数:57论文数:626被引数:1.0万