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D

David E. Gordon

gladstone institutes
H指数:23
被引数:9,896

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Proteotoxic stress response drives T cell exhaustion and immune evasion

蛋白质毒性应激反应驱动T细胞耗竭和免疫逃逸

Nature
IF48.5
2025-10-010
OAAI
Yi Wang; Anjun Ma; No-Joon Song; Ariana E. Shannon; Yaa S. Amankwah; Xingyu Chen; Weidong Wu; Ziyu Wang; Abbey A. Saadey; Amir Yousif; Gautam Ghosh; Jay K. Mandula; Maria Velegraki; Tong Xiao; Haitao Wen; Stanley Ching-Cheng Huang; Ruoning Wang; Christian M. Beusch; Abdelhameed S. Dawood; David E. Gordon; Mohamed S. Abdel-Hakeem; Hazem E. Ghoneim; Gang Xin; Brian C. Searle; Zihai Li
Dynamic In Vivo Mapping of the Methylproteome Using a Chemoenzymatic Approach

利用化学酶法对活体甲基蛋白质组进行动态成像

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
2025-02-250
OA
Farhi, Jonathan; Emenike, Benjamin; Lee, Richard S.; Sad, Kirti; Fawwal, Dorelle V.; Beusch, Christian M.; Jones, Robert B.; Verma, Ashish K.; Jones, Celina Y.; Foroozani, Maryam; Reeves, Monica; Parwani, Kiran K.; Bagchi, Pritha; Deal, Roger B.; Katz, David J.; Corbett, Anita H.; Gordon, David E.; Raj, Monika; Spangle, Jennifer M.
Distinct SIV-specific CD8+ T cells in the lymph node exhibit simultaneous effector and stem-like profiles and are associated with limited SIV persistence
NATURE IMMUNOLOGY
IF27.6
2024-06-176
PRE
Strongin, Zachary; Marchand, Laurence Raymond; Deleage, Claire; Pampena, M. Betina; Cardenas, Maria Andrea; Beusch, Christian Michel; Hoang, Timothy N.; Urban, Elizabeth A.; Gourves, Mael; Nguyen, Kevin; Tharp, Gregory K.; Lapp, Stacey; Rahmberg, Andrew R.; Harper, Justin; Estrada, Perla M. del Rio; Gonzalez-Navarro, Mauricio; Torres-Ruiz, Fernanda; Luna-Villalobos, Yara Andrea; Avila-Rios, Santiago; Reyes-Teran, Gustavo; Sekaly, Rafick; Silvestri, Guido; Kulpa, Deanna A.; Saez-Cirion, Asier; Brenchley, Jason M.; Bosinger, Steven E.; Gordon, David Ezra; Betts, Michael R.; Kissick, Haydn T.; Paiardini, Mirko
Modulation of type I interferon responses potently inhibits SARS-CoV-2 replication and inflammation in rhesus macaques
SCIENCE IMMUNOLOGY
IF16.3
2023-07-2811
OA
Viox, Elise G.; Hoang, Timothy N.; Upadhyay, Amit A.; Nchioua, Rayhane; Hirschenberger, Maximilian; Strongin, Zachary; Tharp, Gregory K.; Pino, Maria; Nguyen, Kevin; Harper, Justin L.; Gagne, Matthew; Marciano, Shir; Boddapati, Arun K.; Pellegrini, Kathryn L.; Pradhan, Arpan; Tisoncik-Go, Jennifer; Whitmore, Leanne S.; Karunakaran, Kirti A.; Roy, Melissa; Kirejczyk, Shannon; Curran, Elizabeth H.; Wallace, Chelsea; Wood, Jennifer S.; Connor-Stroud, Fawn; Voigt, Emily A.; Monaco, Christopher M.; Gordon, David E.; Kasturi, Sudhir P.; Levit, Rebecca D.; Gale, Michael; Vanderford, Thomas H.; Silvestri, Guido; Busman-Sahay, Kathleen; Estes, Jacob D.; Vaccari, Monica; Douek, Daniel C.; Sparrer, Konstantin M. J.; Johnson, R. Paul; Kirchhoff, Frank; Schreiber, Gideon; Bosinger, Steven E.; Paiardini, Mirko
Low expression of EXOSC2 protects against clinical COVID-19 and impedes SARS-CoV-2 replication

EXOSC2的低表达可防止临床新型冠状病毒肺炎并阻止SARS-CoV-2复制

LIFE SCIENCE ALLIANCE
IF2.9
2022-10-141
OAAI
Moll, Tobias; Odon, Valerie; Harvey, Calum; Collins, Mark O.; Peden, Andrew; Franklin, John; Graves, Emily; Marshall, Jack N. G.; Souza, Cleide dos Santos; Zhang, Sai; Castelli, Lydia; Hautbergue, Guillaume; Azzouz, Mimoun; Gordon, David; Krogan, Nevan; Ferraiuolo, Laura; Snyder, Michael P.; Shaw, Pamela J.; Rehwinkel, Jan; Cooper-Knock, Johnathan
Efficient generation of isogenic primary human myeloid cells using CRISPR-Cas9 ribonucleoproteins
CELL REPORTS
IF6.9
2021-05-0136
OAAI
Hiatt, Joseph; Cavero, Devin A.; McGregor, Michael J.; Zheng, Weihao; Budzik, Jonathan M.; Roth, Theodore L.; Haas, Kelsey M.; Wu, David; Rathore, Ujjwal; Meyer-Franke, Anke; Bouzidi, Mohamed S.; Shifrut, Eric; Lee, Youjin; Kumar, Vigneshwari Easwar; Dang, Eric, V; Gordon, David E.; Wojcechowskyj, Jason A.; Hultquist, Judd F.; Fontaine, Krystal A.; Pillai, Satish K.; Cox, Jeffery S.; Ernst, Joel D.; Krogan, Nevan J.; Marson, Alexander
A SARS-CoV-2 protein interaction map reveals targets for drug repurposing
Nature
IF48.5
2020-04-300
PREAI
David E. Gordon; Gwendolyn M. Jang; Mehdi Bouhaddou; Jiewei Xu; Kirsten Obernier; Kris M. White; Matthew J. O’Meara; Veronica V. Rezelj; Jeffrey Z. Guo; Danielle L. Swaney; Tia A. Tummino; Ruth Hüttenhain; Robyn M. Kaake; Alicia L. Richards; Beril Tutuncuoglu; Helene Foussard; Jyoti Batra; Kelsey Haas; Maya Modak; Minkyu Kim; Paige Haas; Benjamin J. Polacco; Hannes Braberg; Jacqueline M. Fabius; Manon Eckhardt; Margaret Soucheray; Melanie J. Bennett; Merve Cakir; Michael J. McGregor; Qiongyu Li; Bjoern Meyer; Ferdinand Roesch; Thomas Vallet; Alice Mac Kain; Lisa Miorin; Elena Moreno; Zun Zar Chi Naing; Yuan Zhou; Shiming Peng; Ying Shi; Ziyang Zhang; Wenqi Shen; Ilsa T. Kirby; James E. Melnyk; John S. Chorba; Kevin Lou; Shizhong A. Dai; Inigo Barrio-Hernandez; Danish Memon; Claudia Hernandez-Armenta; Jiankun Lyu; Christopher J. P. Mathy; Tina Perica; Kala Bharath Pilla; Sai J. Ganesan; Daniel J. Saltzberg; Ramachandran Rakesh; Xi Liu; Sara B. Rosenthal; Lorenzo Calviello; Srivats Venkataramanan; Jose Liboy-Lugo; Yizhu Lin; Xi-Ping Huang; YongFeng Liu; Stephanie A. Wankowicz; Markus Bohn; Maliheh Safari; Fatima S. Ugur; Cassandra Koh; Nastaran Sadat Savar; Quang Dinh Tran; Djoshkun Shengjuler; Sabrina J. Fletcher; Michael C. O’Neal; Yiming Cai; Jason C. J. Chang; David J. Broadhurst; Saker Klippsten; Phillip P. Sharp; Nicole A. Wenzell; Duygu Kuzuoglu-Ozturk; Hao-Yuan Wang; Raphael Trenker; Janet M. Young; Devin A. Cavero; Joseph Hiatt; Theodore L. Roth; Ujjwal Rathore; Advait Subramanian; Julia Noack; Mathieu Hubert; Robert M. Stroud; Alan D. Frankel; Oren S. Rosenberg; Kliment A. Verba; David A. Agard; Melanie Ott; Michael Emerman; Natalia Jura; Mark von Zastrow; Eric Verdin; Alan Ashworth; Olivier Schwartz; Christophe d’Enfert; Shaeri Mukherjee; Matt Jacobson; Harmit S. Malik; Danica G. Fujimori; Trey Ideker; Charles S. Craik; Stephen N. Floor; James S. Fraser; John D. Gross; Andrej Sali; Bryan L. Roth; Davide Ruggero; Jack Taunton; Tanja Kortemme; Pedro Beltrao; Marco Vignuzzi; Adolfo García-Sastre; Kevan M. Shokat; Brian K. Shoichet; Nevan J. Krogan
A Quantitative Genetic Interaction Map of HIV Infection
MOLECULAR CELL
IF16.6
2020-04-0117
OAAI
Gordon, David E.; Watson, Ariane; Roguev, Assen; Zheng, Simin; Jang, Gwendolyn M.; Kane, Joshua; Xu, Jiewei; Guo, Jeffrey Z.; Stevenson, Erica; Swaney, Danielle L.; Franks-Skiba, Kathy; Verschueren, Erik; Shales, Michael; Crosby, David C.; Frankel, Alan D.; Marson, Alexander; Marazzi, Ivan; Cagney, Gerard; Krogan, Nevan J.
Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms
Science
IF45.8
2020-01-010
OAAI
David Ezra Gordon; Joseph B Hiatt; Mehdi Bouhaddou; Veronica V. Rezelj; Svenja Ulferts; Hannes Braberg; Alexander S. Jureka; Kirsten Obernier; Jeffrey Z. Guo; Jyoti Batra; Robyn M. Kaake; Andrew R. Weckstein; Tristan W. Owens; Meghna Gupta; Sergei Pourmal; Erron W. Titus; Merve Çakır; Margaret Soucheray; Michael McGregor; Zeynep Cakir; Gwendolyn Μ. Jang; Matthew J. O’Meara; Tia A. Tummino; Ziyang Zhang; Helene Foussard; Ajda Rojc; Yuan M. Zhou; Dmitry Kuchenov; Ruth Hüttenhain; Jiewei Xu; Manon Eckhardt; Danielle L. Swaney; Jacqueline M. Fabius; Manisha R. Ummadi; Beril Tutuncuoglu; Ujjwal Rathore; Maya Modak; Paige Haas; Kelsey M. Haas; Zun Zar Chi Naing; Ernst H. Pulido; Ying Shi; Inigo Barrio‐Hernandez; Danish Memon; Eirini Petsalaki; Alistair S. Dunham; Miguel Correa Marrero; David F. Burke; Cassandra Koh; Thomas Vallet; Jesus A. Silvas; Caleigh M. Azumaya; Christian B. Billesbølle; Axel F. Brilot; Melody G. Campbell; Amy Diallo; Miles Sasha Dickinson; Devan C. Diwanji; Nadia Herrera; Nick Hoppe; Huong T. Kratochvil; Y.X. Liu; Gregory E. Merz; Michelle Moritz; Henry C. Nguyen; Carlos Nowotny; Cristina Puchades; Alexandrea N. Rizo; Ursula Schulze‐Gahmen; Amber M. Smith; Ming Sun; I.D. Young; Jianhua Zhao; Daniel E. Asarnow; J.T. Biel; Alisa Bowen; Julian R. Braxton; Jen Chen; Cynthia M. Chio; Un Seng Chio; Ishan Deshpande; Loan Doan; Bryan Faust; Sebastian E. Flores; Mingliang Jin; Kate Kim; Victor L. Lam; Fei Li; Junrui Li; Yen-Li Li; Yang Li; Xi Liu; Megan Lo; Kyle Eric Lopez; Arthur Alves de Melo; Frank R. Moss; Phuong Nguyen; Joana Paulino; Komal Ishwar Pawar; Jessica K. Peters; Thomas H. Pospiech; Maliheh Safari; Smriti Sangwan; Kaitlin Schaefer; Paul V. Thomas; Aye C. Thwin; Raphael Trenker; Eric Tse; Tsz Kin Martin Tsui; Feng Wang; Natalie Whitis; Zanlin Yu; Kaihua Zhang; Sunny Zhang; Fengbo Zhou; Daniel J. Saltzberg; Anthony J. Hodder; Amber S. Shun-Shion; Daniel M. Williams; Kris M. White; Romel Rosales; Thomas Kehrer; Lisa Miorin; Elena Moreno; Arvind H. Patel; Suzannah J. Rihn; Mir Mubashir Khalid; Albert Vallejo-Gracia; Parinaz Fozouni; Camille R. Simoneau; Theodore L. Roth; David Wu; Mohd Anisul Karim; Maya Ghoussaini; Ian Dunham; Francesco Berardi; Sebastian Weigang; Maxime Chazal; Jisoo Park; James Logue; Marisa E. McGrath; Stuart M. Weston; Robert E. Haupt; C. James Hastie; Matthew Elliott; Fiona Brown; Kerry A. Burness; Elaine Reid; Mark Dorward; Clare Johnson; Stuart G. Wilkinson; Anna Geyer; Daniel M. Giesel; Carla Baillie; Samantha L. Raggett; Hannah Leech; Rachel L. Toth; Nicola Goodman; Kathleen C. Keough; Abigail Lind; Reyna Klesh; Kafi Hemphill; Jared Carlson-Stevermer; Jennifer Oki; Kevin Holden; Travis J. Maures; Katherine S. Pollard; Andrej Šali; David A. Agard; Yifan Cheng; James S. Fraser; Adam S. Frost; Natalia Jura; Tanja Kortemme; Aashish Manglik; Daniel R. Southworth; Robert Michael Stroud; Dario R. Alessi; Paul Davies; Matthew B. Frieman; Trey E. Ideker; Carmen Abate; Nolwenn Jouvenet; Georg Kochs; Brian K. Shoichet; Mélanie Ott; Massimo Palmarini; Kevan M. Shokat; Adolfo García‐Sastre; Jeremy A. Rassen; Robert Grosse; Oren S. Rosenberg; Kliment A. Verba; Christopher F. Basler; Marco Vignuzzi; Andrew A. Peden; Pedro Beltrão; Nevan J. Krogan; Tristan W. Owens; Meghna Gupta; Sergei Pourmal; Erron W. Titus; Caleigh M. Azumaya; Christian B. Billesbølle; Axel F. Brilot; Melody G. Campbell; Amy Diallo; Miles Sasha Dickinson; Devan C. Diwanji; Nadia Herrera; Nick Hoppe; Huong T. Kratochvil; Y.X. Liu; Gregory E. Merz; Michelle Moritz; Henry C. Nguyen; Carlos Nowotny; Cristina Puchades; Alexandrea N. Rizo; Ursula Schulze‐Gahmen; Amber M. Smith; Ming Sun; I.D. Young; Jianhua Zhao; Daniel E. Asarnow; J.T. Biel; Alisa Bowen; Julian R. Braxton; Jen Chen; Cynthia M. Chio; Un Seng Chio; Ishan Deshpande; Loan Doan; Bryan Faust; Sebastian Flores; Mingliang Jin; Kate Kim; Victor L. Lam; Fei Li; Junrui Li; Yen-Li Li; Yang Li; Xi Liu; Megan Lo; Kyle Eric Lopez; Arthur Alves de Melo; Frank R. Moss; Phuong Nguyen; Joana Paulino; Komal Ishwar Pawar; Jessica K. Peters; Thomas H. Pospiech; Maliheh Safari; Smriti Sangwan; Kaitlin Schaefer; Paul V. Thomas; Aye C. Thwin; Raphael Trenker; Eric Tse; Tsz Kin Martin Tsui; Feng Wang; Natalie Whitis; Zanlin Yu; Kaihua Zhang; Sunny Zhang; Fengbo Zhou; Donovan Trinidad; David A. Agard; Yifan Cheng; James S. Fraser; Adam S. Frost; Natalia Jura; Tanja Kortemme; Aashish Manglik; Daniel R. Southworth; Robert Michael Stroud; Oren S. Rosenberg; Kliment A. Verba; Joana Damas; Graham M. Hughes; Kathleen C. Keough; Corrie Painter; Nicole S. Persky; Marco Corbo; Bodgan Kirilenko; Michael Hiller; Klaus‐Peter Koepfli; Irene M. Kaplow; Morgan E. Wirthlin; Andreas R. Pfenning; Huabin Zhao; Diane P. Genereux; Ross Swofford; Abigail Lind; Katherine S. Pollard; Oliver A. Ryderq; Martin Nweeia; Jennifer R. S. Meadows; Michael X. Dong; Ola Wallerman; Vikki Marinescu; Kerstin Lindblad‐Toh; David A. Ray; Sarahjane Power; Emma C. Teeling; Gaurav Chauhan; Xue Li; Elinor K. Karlsson; Harris A. Lewin

研究方向

暂未获取到该数据
N
Nevan J. Krogan
H 指数:129论文数:759被引数:6.9万
C
Christian M. Beusch
H 指数:16论文数:46被引数:1,049
A
Andrew A. Peden
H 指数:37论文数:96被引数:7,786
R
Ruth Hüttenhain
H 指数:33论文数:79被引数:1.2万
B
Benjamin Emenike
H 指数:6论文数:13被引数:68
T
Trey Ideker
H 指数:108论文数:636被引数:12.1万
A
Alexander Marson
H 指数:59论文数:231被引数:1.9万
J
Joseph Hiatt
H 指数:26论文数:43被引数:1.1万
M
Merve Çakır
H 指数:13论文数:28被引数:7,766
G
Gwendolyn Μ. Jang
H 指数:24论文数:94被引数:1.0万