Bertrand, Kelsey; Hanzlik, Emily; Chiang, Jason; Pinto, Soniya; Selukar, Subodh; Kosteka, Anna; Smith, Kyle; Han, Katie; Ibanez, Jorge; Tlais, Dana; Orr, Brent; Langfitt, Deanna; Metais, Jean-Yves; Lockey, Timothy; Willis, Catherine; Fazio, Frank; Shanmugmam, Raghu; Tian, Liqing; Walhart, Tara; Wang, Yu; Allmon, Patricia; Perry, Scott; Schell, Sarah; Adams, Polly; Ward, Meghan; Meehl, Michaela; Akel, Salem; Poston, Leigh; Bag, Asim; Mack, Stephen; Klimo, Paul; Gajjar, Amar; Thomas, Paul; Crawford, Jeremy; Robinson, Giles; Park, Julie; Northcott, Paul; Gottschalk, Stephen; Krenciute, Giedre; Derenzo, Christopher

Computational structural optimization enhances IL13Rα2 – B7-H3 tandem CAR T cells to overcome antigen-heterogeneity-mediated tumor escape

计算结构优化增强了IL13Rα2–B7-H3串联CAR-T细胞以克服抗原异质性介导的肿瘤逃逸

Molecular Therapy

IF12

2025-08-130

OAAI

LOCOREGIONAL ADMINISTRATION OF B7-H3-CAR T CELLS EXPRESSING 41BB LIGAND FOR PEDIATRIC PATIENTS WITH PRIMARY CNS TUMORS: PRELIMINARY RESULTS FROM A PHASE I STUDY

NEURO-ONCOLOGY

IF13.4

2024-11-110

PRE

Bertrand, Kelsey C.; Kostecka, Anna; Smith, Kyle; Han, Katie; Chiang, Jason; Pinto, Soniya; Tlais, Dana; Selukar, Subodh; Orr, Brent; Hanzlik, Emily; Langfitt, Deanna; Metais, Jean-Yves; Lockey, Timothy; Willis, Catherine; Fazio, Frank; Shanmugam, Raghu; Tian, Liqing; Walhart, Tara; Wang, Yu; Allmon, Patricia; Perry, Scott; Schell, Sarah; Adams, Polly; Ward, Meghan B.; Meehl, Michaela; Akel, Salem; Poston, Leigh; Bag, Asim; Mack, Stephen C.; Leggas, Markos; Klimo, Paul; Gajjar, Amar; Thomas, Paul; Robinson, Giles W.; Park, Julie R.; Crawford, Jeremy Chase; Gottschalk, Stephen; Northcott, Paul A.; Krenciute, Giedre; Derenzo, Christopher

IDENTIFICATION OF CAR-T CELL ENHANCING COMPOUNDS USING HIGH THROUGHPUT SCREENING

NEURO-ONCOLOGY

IF13.4

2024-06-180

OAAI

DELETION OF RASA2 IN CAR T CELLS OVERCOMES DYSFUNCTIONAL IMMUNE SYNAPSE FORMATION AGAINST DIPGS, ENHANCING IN VITRO AND IN VIVO ANTITUMOR RESPONSE

NEURO-ONCOLOGY

IF13.4

2024-06-180

OAAI

IMMUNE SYNAPSE OPTIMIZED GRP78-SPECIFIC CAR T CELLS ELICIT AN IMPROVED ANTITUMOR RESPONSE AGAINST DIPGS

NEURO-ONCOLOGY