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E

Eva Mezeiová

university hospital hradec kralove
H指数:20
被引数:1,053

个人简介

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教育背景

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工作经历

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荣誉奖项

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Balancing rigidity and flexibility: Optimised 4-(hexyloxy)benzoate antagonists with enhanced affinity and tuneable duration at muscarinic receptors

平衡刚性与柔性：具有增强亲和力和可调作用时长的优化4-(己氧基)苯甲酸酯拮抗剂在毒蕈碱受体上

Biomedicine & Pharmacotherapy
IF7.5
2025-10-220
OAAI
Eva Dolejší; Eva Mezeiova; Jana Bláhová; Nikolai Chetverikov; Alena Janoušková-Randáková; Dominik Nelic; Lukas Prchal; Barbora Svobodova; John Boulos; Jan Korabecny; Jan Jakubík
2,6-Disubstituted 7-(naphthalen-2-ylmethyl)-7H-purines as a new class of potent antitubercular agents inhibiting DprE1

2，6-二取代的7-(naphthalen-2-ylmethyl)-7h-嘌呤作为抑制DprE1的新型有效抗结核药

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
2023-10-017
OAAI
Finger, Vladimir; Kucera, Tomas; Kafkova, Radka; Muckova, Lubica; Dolezal, Rafael; Kubes, Jan; Novak, Martin; Prchal, Lukas; Lakatos, Levente; Andrs, Martin; Hympanova, Michaela; Marek, Jan; Kufa, Martin; Spiwok, Vojtech; Soukup, Ondrej; Mezeiova, Eva; Janousek, Jiri; Nevosadova, Lenka; Benkova, Marketa; Kitson, Russell R. A.; Kratky, Martin; Bosze, Szilvia; Mikusova, Katarina; Hartkoorn, Ruben; Roh, Jaroslav; Korabecny, Jan
Novel D2/5-HT receptor modulators related to cariprazine with potential implication to schizophrenia treatment

与cariprazine相关的新型D2/5-HT受体调节剂对精神分裂症的治疗具有潜在意义

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
2022-03-017
PRE
Juza, Radomir; Vojtechova, Iveta; Stefkova-Mazochova, Kristyna; Dehaen, Wim; Petrasek, Tomas; Prchal, Lukas; Kobrlova, Tereza; Janousek, Jiri; Vlcek, Premysl; Mezeiova, Eva; Svozil, Daniel; Karasova, Jana Zdarova; Pejchal, Jaroslav; Stark, Holger; Satala, Grzegorz J.; Bojarski, Andrzej J.; Kubacka, Monika; Mogilski, Szczepan; Randakova, Alena; Musilek, Kamil; Soukup, Ondrej; Korabecny, Jan
Discovery of multifunctional anti-Alzheimer's agents with a unique mechanism of action including inhibition of the enzyme butyrylcholinesterase and γ-aminobutyric acid transporters
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
2021-06-0118
PREAI
Pasieka, Anna; Panek, Dawid; Jonczyk, Jakub; Godyn, Justyna; Szalaj, Natalia; Latacz, Gniewomir; Tabor, Julia; Mezeiova, Eva; Chantegreil, Fabien; Dias, Jose; Knez, Damijan; Lu, Junfeng; Pi, Rongbiao; Korabecny, Jan; Brazzolotto, Xavier; Gobec, Stanislav; Hoefner, Georg; Wanner, Klaus; Wieckowska, Anna; Malawska, Barbara
2-Propargylamino-naphthoquinone derivatives as multipotent agents for the treatment of Alzheimer's disease

2-炔丙基氨基-萘醌衍生物作为治疗阿尔茨海默氏病的多能药物

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
2021-02-0122
PREAI
Mezeiova, Eva; Janockova, Jana; Andrys, Rudolf; Soukup, Ondrej; Kobrlova, Tereza; Muckova, Lubica; Pejchal, Jaroslav; Simunkova, Miriama; Handl, Jiri; Micankova, Petra; Capek, Jan; Rousar, Tomas; Hrabinova, Martina; Nepovimova, Eugenie; Luis Marco-Contelles, Jose; Valko, Marian; Korabecny, Jan
Synthesis, in vitro screening and molecular docking of isoquinolinium-5-carbaldoximes as acetylcholinesterase and butyrylcholinesterase reactivators

乙酰胆碱酯酶和丁酰胆碱酯酶再激活剂isoquinolinium-5-carbaldoximes的合成、体外筛选及分子对接

JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
IF5.4
2020-01-0717
OAAI
Malinak, David; Dolezal, Rafael; Hepnarova, Vendula; Hozova, Miroslava; Andrys, Rudolf; Bzonek, Petr; Racakova, Veronika; Korabecny, Jan; Gorecki, Lukas; Mezeiova, Eva; Psotka, Miroslav; Jun, Daniel; Kuca, Kamil; Musilek, Kamil
Novel tacrine-tryptophan hybrids: Multi-target directed ligands as potential treatment for Alzheimer's disease
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
2019-04-0186
OAAI
Chalupova, Katarina; Korabecny, Jan; Bartolini, Manuela; Monti, Barbara; Lamba, Doriano; Caliandro, Rosanna; Pesaresi, Alessandro; Brazzolotto, Xavier; Gastellier, Anne-Julie; Nachon, Florian; Pejchal, Jaroslav; Jarosova, Michaela; Hepnarova, Vendula; Jun, Daniel; Hrabinova, Martina; Dolezal, Rafael; Karasova, Jana Zdarova; Mzik, Martin; Kristofikova, Zdena; Misik, Jan; Muckova, Lubica; Jost, Petr; Soukup, Ondrej; Benkova, Marketa; Setnicka, Vladimir; Habartova, Lucie; Chvojkova, Marketa; Kleteckova, Lenka; Vales, Karel; Mezeiova, Eva; Uliassi, Elisa; Valis, Martin; Nepovimova, Eugenie; Bolognesi, Maria Laura; Kuca, Kamil

研究方向

暂未获取到该数据
J
Jan Korábečný
H 指数:43论文数:269被引数:6,136
O
Ondřej Soukup
H 指数:41论文数:249被引数:5,493
R
Rafael Doležal
H 指数:27论文数:130被引数:2,277
K
Kamil Kuča
H 指数:92论文数:1,357被引数:4.4万
M
Martina Hrabinová
H 指数:29论文数:135被引数:2,464
Ľ
Ľubica Múčková
H 指数:16论文数:67被引数:970
D
Daniel Jun
H 指数:47论文数:419被引数:8,765
N
Nepovimova, Eugenie
H 指数:0论文数:15被引数:898
J
Jana Janočková
H 指数:22论文数:52被引数:1,510
T
Tereza Kobrlová
H 指数:15论文数:39被引数:613