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L

Lu Chen

The University of Osaka

H指数:16

被引数:868

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Model-informed Drug Development (MIDD) Approach to Support Biopharmaceutical Development of Iberdomide

基于模型的新药开发（MIDD）方法支持伊博domide生物制药开发

IF3.7

2025-04-290

OA

Selective Synthesis of N 6,3′,5′-Tripivaloyladenosine via Dynamic Kinetic Crystallization and Regioselective Preparation of Pivalated 2′-Deoxy-2′-fluoroarabinoadenosines

ORGANIC PROCESS RESEARCH & DEVELOPMENT

IF3.5

2024-10-230

PRE

Model-based analysis for the population pharmacokinetics of iberdomide and its major active metabolite in healthy subjects and patients with relapsed and refractory multiple myeloma

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

IF3

2022-08-297

OAAI

Insight into the Stereocontrol of DNA Polymerase-Catalysed Reaction by Chiral Cobalt Complexes

ADVANCED SYNTHESIS & CATALYSIS

IF4

2022-06-271

PRE

Nitro-Activated Nucleobase Exchange in the Synthesis of 2′-Fluoro-2′-Deoxyribonucleosides

JOURNAL OF ORGANIC CHEMISTRY

IF3.6

2022-06-271

PRE

Glucose-responsive multifunctional metal-organic drug-loaded hydrogel for diabetic wound healing

葡萄糖响应型多功能金属有机载药水凝胶用于糖尿病创面愈合

ACTA BIOMATERIALIA

IF9.6

2022-03-01126

PRE

Nuciferine, an active ingredient derived from lotus leaf, lights up the way for the potential treatment of obesity and obesity-related diseases

PHARMACOLOGICAL RESEARCH

IF10.5

2022-01-0145

PRE

Functional effects of berberine in modulating mitochondrial dysfunction and inflammatory response in the respective amyloidogenic cells and activated microglial cells - In vitro models simulating Alzheimer's disease pathology

IF5.1

2021-10-0121

PREAI

ELABELA alleviates syncytiotrophoblast hypoxia/reoxygenation injury and preeclampsia-like symptoms in mice by reducing apoptosis

IF2.5

2021-03-0124

PREAI

(S)-norketamine and (2S, 6S)-hydroxynorketamine exert potent antidepressant-like effects in a chronic corticosterone-induced mouse model of depression

PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

IF2.5

2020-04-0144

PREAI

Discovery of N-(4-[18F]Fluoro-5-methylpyridin-2-yl)isoquinolin-6-amine (JNJ-64326067), a New Promising Tau Positron Emission Tomography Imaging Tracer (vol 62, pg 2974, 2019)

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2020-02-181

OAAI

Discovery of N-(4-[18F]Fluoro-5-methylpyridin-2-yl)isoquinolin-6-amine (JNJ-64326067), a New Promising Tau Positron Emission Tomography Imaging Tracer

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2019-02-2726

PREAI

Applying Supercritical Fluid Technology to Prepare Ibuprofen Solid Dispersions with Improved Oral Bioavailability

应用超临界流体技术制备口服生物利用度提高的布洛芬固体分散体

IF5.5

2019-02-0316

OAAI

New immobilisation protocol for the template used in solid-phase synthesis of MIP nanoparticles

APPLIED SURFACE SCIENCE

IF6.9

2017-06-0118

PREAI

Development of Decarboxylative Cyanation Reactions for C-13/C-14 Carboxylic Acid Labeling Using an Electrophilic Cyanating Reagent

JOURNAL OF ORGANIC CHEMISTRY

IF3.6

2017-03-1637

PREAI

Discovery of N-(Pyridin-4-yl)-1,5-naphthyridin-2-amines as Potential Tau Pathology PET Tracers for Alzheimer's Disease

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2017-02-1033

PREAI

Trimer procyanidin oligomers contribute to the protective effects of cinnamon extracts on pancreatic β-cells in vitro

ACTA PHARMACOLOGICA SINICA

IF8.4

2016-05-3039

OAAI

Molecular characterization of heteroatomic compounds in a high-temperature coal tar using three mass spectrometers

使用三个质谱仪对高温煤焦油中的杂原子化合物进行分子表征

FUEL PROCESSING TECHNOLOGY

IF7.7

2015-10-0158

PREAI

Two New Secondary Metabolites from Xylaria sp cfcc 87468

IF4.6

2014-01-2014

OAAI

Self-assembly of interpenetrated supramolecular networks by C-H•••π interaction

互穿超分子网络的c-h • π 相互作用自组装

JOURNAL OF MOLECULAR STRUCTURE

IF4.7

2013-04-015

PREAI