Feilong Zhou - Publications, H-index & Citations

Feilong Zhou

nankai university

18H指数

58论文数

845被引数

收录论文 36

发表时间

Discovery of novel hydroxycamptothecin derivatives as potent Topo I inhibitors for antitumor guided by molecular dynamics 基于分子动力学的抗肿瘤新型羟基喜树碱衍生物作为强效拓扑异构酶I抑制剂的发现

European Journal of Medicinal Chemistry

IF5.9

2026-07-01

PREAI

Zhang, Yixuan; Wang, Hong; Zhou, Feilong; Wang, Guangming; Zhu, Meilin; Fan, Fangtian; Liu, Xinhua

Chimeras co-targeting antigens and FcγRIIb trigger degradation of extracellular soluble proteins and pathological aggregates 嵌合体同时靶向抗原和FcγRIIb，可触发细胞外可溶性蛋白质及病理性聚集物的降解。

Nature Communications

IF15.7

2025-12-10

OAAI

Mingjuan Du; Na Li; Tianqi Li; Zhuoqian Zhao; Huanzhen Liu; Xin Li; Nanxin Gong; Baoxin Duan; Wenli Wang; Yi Jian; Wenxuan Ma; Xiaoqi Zhang; Yi Wang; Zhaoyuan Zhang; Yiyang Bai; Xiaoqian Wang; Chunlei Wang; Jinming Liu; Xiangchen Guan; Feilong Zhou; Wei Wang; Lili Li; Xingping Zhu; Ying Lei; Yinkai Duan; Guoge Han; Pinghui Wei; Shan Gao; Sheng Wang; Ancheng Chen; Yi Huang; Haitao Yang; Xue Xue; Hongkai Zhang

Design and synthesis of a 1,3,6-trimethyl-1H-benzo[d]imidazole-5-sulfonamide derivative as a type I CDK8 inhibitor against colorectal cancer 1,3,6-三甲基-1H-苯并[d]咪唑-5-磺酰胺衍生物的设计与合成，作为针对结直肠癌的I型CDK8抑制剂

Bioorganic Chemistry

IF4.7

2025-11-26

PREAI

Juncheng Du; Yu Zhang; Daxing Shi; Cui Chang; Feilong Zhou; Jin Dong; Yaoyao Yan; Xinhua Liu

Identification of Marrubiin as a Cathepsin C Inhibitor for Treating Rheumatoid Arthritis 将Marrubiin鉴定为一种用于治疗类风湿性关节炎的半胱天冬酶C抑制剂

Molecules 2025, Vol. 30, Page 4170

IF0

2025-10-23

OAAI

Fei-Long Zhou; Yu Zhang; Cui Chang; Da-Xing Shi; Xing Chen; Xin-Hua Liu; Xiao-Bao Shen

Susceptibility and Protective Genes in Diabetic Retinopathy: A Comprehensive Single-Cell RNA Sequencing Analysis 糖尿病视网膜病变中的易感基因与保护基因：一项全面的单细胞RNA测序分析

Experimental Eye Research

IF2.7

2025-10-10

PREAI

Jingqiu Li; Xinyang Hu; Hui Zhang; Yuming Li; Feilong Zhou; Dan Li; Haibo Zhang; Siqi Fan; Bing Shen; Yong Wang

USP39 at the crossroads of cancer immunity: regulating immune evasion and immunotherapy response through RNA splicing and ubiquitin signaling USP39在癌症免疫中的关键作用：通过RNA剪接和泛素信号调节免疫逃逸和免疫治疗反应

Frontiers in Immunology

IF5.9

2025-09-08

OAAI

Feilong Zhou†; Xinhao Li†; Yanmei Sun†; Yizhu Wang†; Kaiyi Niu; Xin Gao; Jiaqi Zhang; Tianyi Chen; Yunxin Li; Weijie Zhao; Binyue Mao; Qiyang Xu; Yanlong Shi; Zhenyu He

Identification of high corrosion failure probability in shale gas gathering and transportation pipeline segments 页岩气集输管道段高腐蚀失效概率的识别

ENGINEERING FAILURE ANALYSIS

IF5.7

2025-05-22

PREAI

Qin, Min; Jiang, Xinhui; Zhang, Shijian; Zhou, Feilong; He, Guoxi; Liao, Kexi

Single-cell data-driven design of armed oncolytic virus to boost cooperative innate-adaptive immunity against cancer 单细胞数据驱动的武装溶瘤病毒设计，以增强协同固有免疫与适应性免疫对抗癌症

MOLECULAR THERAPY

IF12

2025-02-01

OAAI

Zhao, Jiliang; Wang, Han; Wang, Chunlei; Li, Fan; Chen, Jingru; Zhou, Feilong; Zhu, Yiping; Chen, Jinhua; Liu, Jinming; Zheng, Hao; Du, Yazhuo; Deng, Li; Du, Yuyao; Liu, Yanqin; Li, Yuanke; Li, Na; Zhang, Hongru; Yu, Shouzhi; Zhang, Cuizhu; Yan, Yingbin; Wang, Wei; Cao, Youjia; Zhang, Yuntao; Zhang, Hongkai

Emerging discoveries on the role of TRIM14: from diseases to immune regulation

CELL DEATH DISCOVERY

IF7

2024-12-24

OAAI

Li, Xinhao; Zhou, Feilong; Niu, Kaiyi; Wang, Yizhu; Shi, Yanlong; Li, Yunxin; Gao, Xin; Zhao, Weijie; Chen, Tianyi; Zhang, Yewei

Identification of novel indolinone derivatives as CTSC inhibitors to treat inflammatory bowel disease by modulating inflammatory factors 鉴定新型吲哚酮衍生物作为CTSC抑制剂通过调节炎症因子治疗炎症性肠病

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2024-12-01

PREAI

Chen, Xing; Lou, Yan; Zhou, Feilong; Shi, Daxing; Liu, Xinhua; Tao, Fangbiao

Reduction of circulating IgE and allergens by a pH-sensitive antibody with enhanced FcyRIIb binding 通过一种pH敏感抗体并增强FcyRIIb结合来减少循环IgE和过敏原

MOLECULAR THERAPY

IF12

2024-10-01

PREAI

Li, Na; Gong, Nanxin; Duan, Baoxin; Zhang, Yongyan; Jian, Yi; Xu, Yanqin; Liu, Jinming; Wang, Xiaoqian; Zhang, Xiaoqi; Du, Mingjuan; Zhou, Feilong; Zhao, Jiliang; Guan, Xiangchen; Peng, Xiangda; Wang, Sheng; Zhang, Hongkai

A review: targeting UBR5 domains to mediate emerging roles and mechanisms - chance or necessity?

INTERNATIONAL JOURNAL OF SURGERY

IF10.1

2024-08-01

OAAI

Wang, Yizhu; Niu, Kaiyi; Shi, Yanlong; Zhou, Feilong; Li, Xinhao; Li, Yunxin; Chen, Tianyi; Zhang, Yewei

Synthesis and biological evaluation of 4-imidazolidinone-containing compounds as potent inhibitors of the MDM2/p53 interaction

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2024-04-01

PREAI

Lin, Zhitong; Liu, Chen; Yan, Ziqin; Cheng, Jing; Wang, Xiancheng; Zhou, Feilong; Lyu, Xilin; Zhang, Shiyan; Zhang, Daizhou; Meng, Xiangjing; Zhao, Yujun

Discovery of an effective anti-inflammatory agent for inhibiting the activation of NF-κB

JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

IF5.4

2023-06-16

OAAI

Yan, Yaoyao; Qi, Lv; Zhou, Feilong; Jian, Yujie; Liu, Xinhua; Xing, Chen; Yong, Hu

A chemical perspective on the modulation of TEAD transcriptional activities: Recent progress, challenges, and opportunities TEAD转录活性调节的化学观点: 最新进展，挑战和机遇

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2022-12-01

PREAI

Lou, Jianfeng; Lu, Yuhang; Cheng, Jing; Zhou, Feilong; Yan, Ziqin; Zhang, Daizhou; Meng, Xiangjing; Zhao, Yujun

Discovery of a selective and covalent small-molecule inhibitor of BFL-1 protein that induces robust apoptosis in cancer cells

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2022-06-01

PREAI

Feng, Xuexin; Yan, Ziqin; Zhou, Feilong; Lou, Jianfeng; Lyu, Xilin; Ren, Xuelian; Zeng, Ziyu; Liu, Chenglong; Zhang, Shiyan; Zhu, Di; Huang, He; Yang, Jinming; Zhao, Yujun

CBr4 Mediated [4+1] Dehydrocyclization for the Synthesis of Functionalized Imidazo[1,5-a]heterocycles from Pyridin-2-ylmethanamines and Aldehydes

ACS OMEGA

IF4.3

2021-08-02

OAAI

Wang, Qiang; Zha, Meng; Zhou, Feilong; Chen, Xixi; Wang, Baiyu; Liu, Guodong; Qian, Lisheng

Recent Progress and Clinical Development of Inhibitors that Block MDM4/p53 Protein-Protein Interactions

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2021-07-21

PREAI

Zhang, Shiyan; Lou, Jianfeng; Li, Yafang; Zhou, Feilong; Yan, Ziqin; Lyu, Xilin; Zhao, Yujun

Discovery of a novel, potent and selective small-molecule inhibitor of PD-1/PD-L1 interaction with robust in vivo anti-tumour efficacy

BRITISH JOURNAL OF PHARMACOLOGY

IF7.7

2021-05-04

OAAI

Liu, Chenglong; Zhou, Feilong; Yan, Ziqin; Shen, Lian; Zhang, Xichen; He, Fenglian; Wang, Heng; Lu, Xiaojie; Yu, Ker; Zhao, Yujun; Zhu, Di

Pharmacological inhibition of NF-κB-inducing kinase (NIK) with small molecules for the treatment of human diseases

RSC MEDICINAL CHEMISTRY

IF3.6

2021-01-01

OAAI

Cheng, Jing; Feng, Xuexin; Li, Zhiqiang; Zhou, Feilong; Yang, Jin-Ming; Zhao, Yujun

研究方向