Rosanne M. Crooke - Publications, H-index & Citations

Rosanne M. Crooke

ionis pharmaceuticals inc.

52H指数

204论文数

1.3W被引数

收录论文 75

发表时间

Foamy monocytes and atherogenesis in mice with combined hyperlipidemia and effects of antisense knockdown of apoCIII 泡沫单核细胞和联合高脂血症小鼠中的动脉粥样硬化形成及抗 apoCIII 反义寡核苷酸敲低的影响

JOURNAL OF LIPID RESEARCH

IF4.1

2025-02-01

OAAI

Peng, Xueying; Lian, Zeqin; O'Brien, Veronica; Xiao, Jing; Litchfield, Benjamin A.; Perrard, Xiao-Yuan Dai; Xu, Lu; Ni, Jing; Mukherjee, Aparna; Simmons, Timothy; Dong, Henry; Mullick, Adam E.; Crooke, Rosanne; Pownall, Henry J.; Simon, Scott I.; Ballantyne, Christie M.; Wu, Huaizhu

Interventional hepatic apoC-III knockdown improves atherosclerotic plaque stability and remodeling by triglyceride lowering

JCI INSIGHT

IF6.1

2022-07-08

OAAI

Ramms, Bastian; Patel, Sohan; Sun, Xiaoli; Pessentheiner, Ariane R.; Ducasa, G. Michelle; Mullick, Adam E.; Lee, Richard G.; Crooke, Rosanne M.; Tsimikas, Sotirios; Witztum, Joseph L.; Gordts, Philip L. S. M.; Witztum, Joseph L.

Insulin Prevents Hypercholesterolemia by Suppressing 12α-Hydroxylated Bile Acids

CIRCULATION

IF38.6

2022-03-29

OAAI

Semova, Ivana; Levenson, Amy E.; Krawczyk, Joanna; Bullock, Kevin; Gearing, Mary E.; Ling, Alisha, V; Williams, Kathryn A.; Miao, Ji; Adamson, Stuart S.; Shin, Dong-Ju; Chahar, Satyapal; Graham, Mark J.; Crooke, Rosanne M.; Hagey, Lee R.; Vicent, David; de Ferranti, Sarah D.; Kidambi, Srividya; Clish, Clary B.; Biddinger, Sudha B.

Antisense drug discovery and development technology considered in a pharmacological context

BIOCHEMICAL PHARMACOLOGY

IF5.6

2021-07-01

PREAI

Crooke, Stanley T.; Liang, Xue-hai; Crooke, Rosanne M.; Baker, Brenda F.; Geary, Richard S.

An oral antisense oligonucleotide for PCSK9 inhibition

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2021-05-12

PREAI

Gennemark, Peter; Walter, Katrin; Clemmensen, Niclas; Rekic, Dinko; Nilsson, Catarina A. M.; Knochel, Jane; Holtta, Mikko; Wernevik, Linda; Rosengren, Birgitta; Kakol-Palm, Dorota; Wang, Yanfeng; Yu, Rosie Z.; Geary, Richard S.; Riney, Stan J.; Monia, Brett P.; Isaksson, Rikard; Jansson-Lofmark, Rasmus; Rocha, Cristina S. J.; Linden, Daniel; Hurt-Camejo, Eva; Crooke, Rosanne; Tillman, Lloyd; Ryden-Bergsten, Tina; Carlsson, Bjorn; Andersson, Ulf; Elebring, Marie; Tivesten, Anna; Davies, Nigel

Antisense technology: an overview and prospectus

NATURE REVIEWS DRUG DISCOVERY

IF101.8

2021-03-24

426

PREAI

Crooke, Stanley T.; Baker, Brenda F.; Crooke, Rosanne M.; Liang, Xue-hai

Antisense oligonucleotide-mediated inhibition of angiopoietin-like protein 3 increases reverse cholesterol transport in mice

JOURNAL OF LIPID RESEARCH

IF4.1

2021-01-01

OAAI

Bell, Thomas A., III; Liu, Mingxia; Donner, Aaron J.; Lee, Richard G.; Mullick, Adam E.; Crooke, Rosanne M.

Antisense technology: A review

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2021-01-01

165

OAAI

Crooke, Stanley T.; Liang, Xue-Hai; Baker, Brenda F.; Crooke, Rosanne M.

Dyrk1a Antisense Oligonucleotides Conjugated to GLP-1R Agonist Promote Pancreatic Beta-Cell Proliferation

DIABETES

IF7.5

2020-06-01

PREAI

Fu, Wuxia; Lee, Richard; Pirie, Elaine C.; Prakash, Thazha; Murray, Sue; Powers, Andrew; Mullick, Adam E.; Crooke, Rosanne M.

Phosphatidylinositol-(4,5)-Bisphosphate Regulates Plasma Cholesterol Through LDL (Low-Density Lipoprotein) Receptor Lysosomal Degradation

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

IF7.4

2020-05-01

OAAI

Qin, Yuanyuan; Ting, Flora; Kim, Mee J.; Strelnikov, Jacob; Harmon, Joseph; Gao, Feng; Dose, Andrea; Teng, Ba-Bie; Alipour, Mohsen Amir; Yao, Zemin; Crooke, Rosanne; Krauss, Ronald M.; Medina, Marisa W.

Trimethylamine N-Oxide Binds and Activates PERK to Promote Metabolic Dysfunction

CELL METABOLISM

IF30.9

2019-12-01

258

OAAI

Chen, Sifan; Henderson, Ayana; Petriello, Michael C.; Romano, Kymberleigh A.; Gearing, Mary; Miao, Ji; Schell, Mareike; Sandoval-Espinola, Walter J.; Tao, Jiahui; Sha, Bingdong; Graham, Mark; Crooke, Rosanne; Kleinridders, Andre; Balskus, Emily P.; Rey, Federico E.; Morris, Andrew J.; Biddinger, Sudha B.

Obesity-linked suppression of membrane-bound O-acyltransferase 7 (MBOAT7) drives non-alcoholic fatty liver disease

ELIFE

IF0

2019-10-17

OAAI

Helsley, Robert N.; Varadharajan, Venkateshwari; Brown, Amanda L.; Gromovsky, Anthony D.; Schugar, Rebecca C.; Ramachandiran, Iyappan; Fung, Kevin; Kabbany, Mohammad Nasser; Banerjee, Rakhee; Neumann, Chase K.; Finney, Chelsea; Pathak, Preeti; Orabi, Danny; Osborn, Lucas J.; Massey, William; Zhang, Renliang; Kadam, Anagha; Sansbury, Brian E.; Pan, Calvin; Sacks, Jessica; Lee, Richard G.; Crooke, Rosanne M.; Graham, Mark J.; Lemieux, Madeleine E.; Gogonea, Valentin; Kirwan, John P.; Allende, Daniela S.; Civelek, Mete; Fox, Paul L.; Rudel, Lawrence L.; Lusis, Aldons J.; Spite, Matthew; Brown, J. Mark

Hybrid Mouse Diversity Panel Identifies Genetic Architecture Associated with the Acute Antisense Oligonucleotide-Mediated Inflammatory Response to a 2′-O-Methoxyethyl Antisense Oligonucleotide

NUCLEIC ACID THERAPEUTICS

IF4.7

2019-10-01

OAAI

Pirie, Elaine; Cauntay, Patrick; Fu, Wuxia; Ray, Shayoni; Pan, Calvin; Lusis, Aldonis J.; Hsiao, Jill; Burel, Sebastien A.; Narayanan, Padma; Crooke, Rosanne M.; Lee, Richard G.

Increased apolipoprotein C3 drives cardiovascular risk in type 1 diabetes

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2019-08-26

OAAI

Kanter, Jenny E.; Shao, Baohai; Kramer, Farah; Barnhart, Shelley; Shimizu-Albergine, Masami; Vaisar, Tomas; Graham, Mark J.; Crooke, Rosanne M.; Manuel, Clarence R.; Haeusler, Rebecca A.; Mar, Daniel; Bomsztyk, Karol; Hokanson, John E.; Kinney, Gregory L.; Snell-Bergeon, Janet K.; Heinecke, Jay W.; Bornfeldt, Karin E.

GLP-1 Conjugation Enhances the Activity of Antisense Oligonucleotides Targeting Islet Amyloid Polypeptide (IAPP) or Kelch-Like ECH Associated Protein 1 (Keapl) in Isolated Pancreatic Islets

DIABETES

IF7.5

2019-06-01

PREAI

Fu, Wuxia; Lee, Richard; Pirie, Elaine C.; Prakash, Thazha; Murray, Sue; Powers, Andrew F.; Crooke, Rosanne M.

Chemical modification of PS-ASO therapeutics reduces cellular protein-binding and improves the therapeutic index Ps-aso治疗剂的化学修饰减少了细胞蛋白结合并提高了治疗指数

NATURE BIOTECHNOLOGY

IF41.7

2019-04-29

220

PREAI

Shen, Wen; De Hoyos, Cheryl L.; Migawa, Michael T.; Vickers, Timothy A.; Sun, Hong; Low, Audrey; Bell, Thomas A., III; Rahdar, Meghdad; Mukhopadhyay, Swagatam; Hart, Christopher E.; Bell, Melanie; Riney, Stan; Murray, Susan F.; Greenlee, Sarah; Crooke, Rosanne M.; Liang, Xue-hai; Seth, Punit P.; Crooke, Stanley T.

Antisense oligonucleotides targeting angiotensinogen: insights from animal studies

BIOSCIENCE REPORTS

IF4.7

2019-01-11

OAAI

Wu, Chia-Hua; Wang, Ya; Ma, Murong; Mullick, Adam E.; Crooke, Rosanne M.; Graham, Mark J.; Daugherty, Alan; Lu, Hong S.

Mouse genome-wide association studies and systems genetics uncover the genetic architecture associated with hepatic pharmacokinetic and pharmacodynamic properties of a constrained ethyl antisense oligonucleotide targeting Malat1

PLOS GENETICS

IF3.7

2018-10-29

OAAI

Pirie, Elaine; Ray, Shayoni; Pan, Calvin; Fu, Wuxia; Powers, Andrew F.; Polikoff, Danielle; Miller, Colton M.; Kudrna, Katrina M.; Harris, Edward N.; Lusis, Aldons J.; Crooke, Rosanne M.; Lee, Richard G.

Blood Pressure Lowering and Safety Improvements With Liver Angiotensinogen Inhibition in Models of Hypertension and Kidney Injury

HYPERTENSION

IF8.2

2017-09-01

OAAI

Mullick, Adam E.; Yeh, Steve T.; Graham, Mark J.; Engelhardt, Jeffery A.; Prakash, Thazha P.; Crooke, Rosanne M.

Antisense oligonucleotides targeting translation inhibitory elements in 5′ UTRs can selectively increase protein levels

NUCLEIC ACIDS RESEARCH

IF13.1

2017-07-21

OAAI

Liang, Xue-hai; Sun, Hong; Shen, Wen; Wang, Shiyu; Yao, Joyee; Migawa, Michael T.; Huynh-Hoa Bui; Damle, Sagar S.; Riney, Stan; Graham, Mark J.; Crooke, Rosanne M.; Crooke, Stanley T.

研究方向