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Small Molecule Inhibition of CPS1 Activity through an Allosteric Pocket Yao, Shihua; Tuong-Vi Nguyen; Rolfe, Alan; Agrawal, Anant A.; Ke, Jiyuan; Peng, Shouyong; Colombo, Federico; Yu, Sean; Bouchard, Patricia; Wu, Jiayi; Huang, Kuan-Chun; Bao, Xingfeng; Omoto, Kiyoyuki; Selvaraj, Anand; Yu, Lihua; Ioannidis, Stephanos; Vaillancourt, Frederic H.; Zhu, Ping; Larsen, Nicholas A.; Bolduc, David M. 分享 收藏
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H3B-8800, an orally available small-molecule splicing modulator, induces lethality in spliceosome-mutant cancers Seiler, Michael; Yoshimi, Akihide; Darman, Rachel; Chan, Betty; Keaney, Gregg; Thomas, Michael; Agrawal, Anant A.; Caleb, Benjamin; Csibi, Alfredo; Sean, Eckley; Fekkes, Peter; Karr, Craig; Klimek, Virginia; Lai, George; Lee, Linda; Kumar, Pavan; Lee, Stanley Chun-Wei; Liu, Xiang; Mackenzie, Crystal; Meeske, Carol; Mizui, Yoshiharu; Padron, Eric; Park, Eunice; Pazolli, Ermira; Peng, Shouyong; Prajapati, Sudeep; Taylor, Justin; Teng, Teng; Wang, John; Warmuth, Markus; Yao, Huilan; Yu, Lihua; Zhu, Ping; Abdel-Wahab, Omar; Smith, Peter G.; Buonamici, Silvia 分享 收藏
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A chemogenomic approach reveals the action of splicing modulators at the branch point adenosine binding pocket defined by the PHF5A/SF3b complex Teng, Teng; Tsai, Jennifer; Puyang, Xiaoling; Seiler, Michael; Peng, Shouyong; Aird, Daniel; Buonamici, Silvia; Caleb, Benjamin; Chan, Betty; Corson, Laura; Feala, Jacob; Fekkes, Peter; Karr, Craig; Korpal, Manav; Mizui, Yoshiharu; Park, Eunice; Palacino, James; Smith, Peter; Subramanian, Vanitha; Wu, Jeremy; Yu, Lihua; Chicas, Agustin; Warmuth, Markus; Larsen, Nicholas; Zhu, Ping 分享 收藏
Splicing modulators act at the branch point adenosine binding pocket defined by the PHF5A-SF3b complex Teng, Teng; Tsai, Jennifer H. C.; Puyang, Xiaoling; Seiler, Michael; Peng, Shouyong; Prajapati, Sudeep; Aird, Daniel; Buonamici, Silvia; Caleb, Benjamin; Chan, Betty; Corson, Laura; Feala, Jacob; Fekkes, Peter; Gerard, Baudouin; Karr, Craig; Korpal, Manav; Liu, Xiang; Lowe, Jason T.; Mizui, Yoshiharu; Palacino, James; Park, Eunice; Smith, Peter G.; Subramanian, Vanitha; Wu, Zhenhua Jeremy; Zou, Jian; Yu, Lihua; Chicas, Agustin; Warmuth, Markus; Larsen, Nicholas; Zhu, Ping 分享 收藏
Identification of PHF5A as a common cellular target of splicing-modulating chemical probes Teng, Teng; Puyang, Xiaoling; Peng, Shouyong; Feala, Jacob; Chan, Betty; Tsai, Jennifer; Caleb, Benjamin; Karr, Craig; Park, Eunice; Corson, Laura; Mizui, Yoshiharu; Smith, Peter; Larsen, Nicholas; Yu, Lihua; Warmuth, Markus; Zhu, Ping; Chicas, Agustin 分享 收藏
Cancer-Associated SF3B1 Hotspot Mutations Induce Cryptic 3′ Splice Site Selection through Use of a Different Branch Point 癌症相关的SF3B1热点突变通过使用不同的分支点诱导隐蔽的3' 剪接位点选择 Darman, Rachel B.; Seiler, Michael; Agrawal, Anant A.; Lim, Kian H.; Peng, Shouyong; Aird, Daniel; Bailey, Suzanna L.; Bhavsar, Erica B.; Chan, Betty; Colla, Simona; Corson, Laura; Feala, Jacob; Fekkes, Peter; Ichikawa, Kana; Keaney, Gregg F.; Lee, Linda; Kumar, Pavan; Kunii, Kaiko; MacKenzie, Crystal; Matijevic, Mark; Mizui, Yoshiharu; Myint, Khin; Park, Eun Sun; Puyang, Xiaoling; Selvaraj, Anand; Thomas, Michael P.; Tsai, Jennifer; Wang, John Y.; Warmuth, Markus; Yang, Hui; Zhu, Ping; Garcia-Manero, Guillermo; Furman, Richard R.; Yu, Lihua; Smith, Peter G.; Buonamici, Silvia 分享 收藏
Dynamic Epigenetic Regulation by Menin During Pancreatic Islet Tumor Formation Lin, Wenchu; Watanabe, Hideo; Peng, Shouyong; Francis, Joshua M.; Kaplan, Nathan; Pedamallu, Chandra Sekhar; Ramachandran, Aruna; Agoston, Agoston; Bass, Adam J.; Meyerson, Matthew 分享 收藏
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Preexisting oncogenic events impact trastuzumab sensitivity in ERBB2-amplified gastroesophageal adenocarcinoma Kim, Jihun; Fox, Cameron; Peng, Shouyong; Pusung, Mark; Pectasides, Eirini; Matthee, Eric; Hong, Yong Sang; Do, In-Gu; Jang, Jiryeon; Thorner, Aaron R.; Van Hummelen, Paul; Rustgi, Anil K.; Wong, Kwok-Kin; Zhou, Zhongren; Tang, Ping; Kim, Kyoung-Mee; Lee, Jeeyun; Bass, Adam J. 分享 收藏
SOX2-p63 interaction and genomic co-localization in squamous cell carcinomas Watanabe, Hideo; Ma, Qiuping; Peng, Shouyong; Adelmant, Guillaume; Swain, Danielle; Song, Wenyu; Fox, Cameron; Francis, Joshua M.; Pedamallu, Chandra Sekhar; Deluca, David S.; Brooks, Angela N.; Que, Jianwen; Rustgi, Anil K.; Wong, Kwok-kin; Ligon, Keith L.; Liu, X. Shirley; Marto, Jarrod A.; Meyerson, Matthew; Bass, Adam J. 分享 收藏
Analyses of clinicopathological, molecular, and prognostic associations of KRAS codon 61 and codon 146 mutations in colorectal cancer: cohort study and literature review Imamura, Yu; Lochhead, Paul; Yamauchi, Mai; Kuchiba, Aya; Qian, Zhi Rong; Liao, Xiaoyun; Nishihara, Reiko; Jung, Seungyoun; Wu, Kana; Nosho, Katsuhiko; Wang, Yaoyu E.; Peng, Shouyong; Bass, Adam J.; Haigis, Kevin M.; Meyerhardt, Jeffrey A.; Chan, Andrew T.; Fuchs, Charles S.; Ogino, Shuji 分享 收藏
SOX2 and p63 colocalize at genetic loci in squamous cell carcinomas Watanabe, Hideo; Ma, Qiuping; Peng, Shouyong; Adelmant, Guillaume; Swain, Danielle; Song, Wenyu; Fox, Cameron; Francis, Joshua M.; Pedamallu, Chandra Sekhar; DeLuca, David S.; Brooks, Angela N.; Wang, Su; Que, Jianwen; Rustgi, Anil K.; Wong, Kwok-kin; Ligon, Keith L.; Liu, X. Shirley; Marto, Jarrod A.; Meyerson, Matthew; Bass, Adam J. 分享 收藏
Exome and whole-genome sequencing of esophageal adenocarcinoma identifies recurrent driver events and mutational complexity Dulak, Austin M.; Stojanov, Petar; Peng, Shouyong; Lawrence, Michael S.; Fox, Cameron; Stewart, Chip; Bandla, Santhoshi; Imamura, Yu; Schumacher, Steven E.; Shefler, Erica; McKenna, Aaron; Carter, Scott L.; Cibulskis, Kristian; Sivachenko, Andrey; Saksena, Gordon; Voet, Douglas; Ramos, Alex H.; Auclair, Daniel; Thompson, Kristin; Sougnez, Carrie; Onofrio, Robert C.; Guiducci, Candace; Beroukhim, Rameen; Zhou, Zhongren; Lin, Lin; Lin, Jules; Reddy, Rishindra; Chang, Andrew; Landrenau, Rodney; Pennathur, Arjun; Ogino, Shuji; Luketich, James D.; Golub, Todd R.; Gabriel, Stacey B.; Lander, Eric S.; Beer, David G.; Godfrey, Tony E.; Getz, Gad; Bass, Adam J. 分享 收藏
Mutant N-RAS Protects Colorectal Cancer Cells from Stress-Induced Apoptosis and Contributes to Cancer Development and Progression Wang, Yufang; Velho, Sergia; Vakiani, Efsevia; Peng, Shouyong; Bass, Adam J.; Chu, Gerald C.; Gierut, Jessica; Bugni, James M.; Der, Channing J.; Philips, Mark; Solit, David B.; Haigis, Kevin M. 分享 收藏
Identification of Chromatin-Associated Regulators of MSL Complex Targeting in Drosophila Dosage Compensation Larschan, Erica; Soruco, Marcela M. L.; Lee, Ok-Kyung; Peng, Shouyong; Bishop, Eric; Chery, Jessica; Goebel, Karen; Feng, Jessica; Park, Peter J.; Kuroda, Mitzi I. 分享 收藏
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