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J

Jeremy L. Jenkins

novartis biomedical research
H指数:46
被引数:8,617

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A conformation-sensitive product inhibitor of HDAC1/2 potentiates WNT signaling

HDAC1/2的构象敏感型产物抑制剂可增强WNT信号通路

Nature Chemical Biology
IF13.7
2026-11-110
PRE
Olga Charlat; Ling Li; Zheng Zhou; Rohan EJ Beckwith; Lijian Feng; Liqing Geng; Aleem Fazal; Jason R. Thomas; Jason Murphy; Nicolas Pizzato; Fabian Wu; Judith Knehr; Sebastian Bergling; Helen T. Pham; Daniel Fuller; Deborah I. Scheffer; Zijun Chen; Jun Gao; Daniel S. Palacios; Stephen M. Canham; Gregory A. Michaud; Claude Shelton; Scott M. Brittain; Marc Hild; Kristie Wetzel; Paola Capodieci; Frederic Sigoillot; Jeremy L. Jenkins; Jeffery A. Porter; En Li; John A. Tallarico; Markus Schirle; Barna D. Fodor; Justin Gu; Feng Cong
Enhancing the Small-Scale Screenable Biological Space beyond Known Chemogenomics Libraries with Gray Chemical Matter-Compounds with Novel Mechanisms from High-Throughput Screening Profiles
ACS CHEMICAL BIOLOGY
IF3.8
2024-04-023
OAAI
Thomas, Jason R.; Shelton, Claude; Murphy, Jason; Brittain, Scott; Bray, Mark-Anthony; Aspesi, Peter; Concannon, John; King, Frederick J.; Ihry, Robert J.; Ho, Daniel J.; Henault, Martin; Hadjikyriacou, Andrea; Neri, Marilisa; Sigoillot, Frederic D.; Pham, Helen T.; Shum, Matthew; Barys, Louise; Jones, Michael D.; Martin, Eric J.; Blechschmidt, Anke; Rieffel, Sebastien; Troxler, Thomas J.; Mapa, Felipa A.; Jenkins, Jeremy L.; Jain, Rishi K.; Kutchukian, Peter S.; Schirle, Markus; Renner, Steffen
Activation of human STING by a molecular glue-like compound

通过分子胶样化合物激活人类STING

NATURE CHEMICAL BIOLOGY
IF13.7
2023-10-1211
OAAI
Li, Jie; Canham, Stephen M.; Wu, Hua; Henault, Martin; Chen, Lihao; Liu, Guoxun; Chen, Yu; Yu, Gary; Miller, Howard R.; Hornak, Viktor; Brittain, Scott M.; Michaud, Gregory A.; Tutter, Antonin; Broom, Wendy; Digan, Mary Ellen; Mcwhirter, Sarah M.; Sivick, Kelsey E.; Pham, Helen T.; Chen, Christine H.; Tria, George S.; Mckenna, Jeffery M.; Schirle, Markus; Mao, Xiaohong; Nicholson, Thomas B.; Wang, Yuan; Jenkins, Jeremy L.; Jain, Rishi K.; Tallarico, John A.; Patel, Sejal J.; Zheng, Lianxing; Ross, Nathan T.; Cho, Charles Y.; Zhang, Xuewu; Bai, Xiao-Chen; Feng, Yan
CYP27A1-dependent anti-melanoma activity of limonoid natural products targets mitochondrial metabolism
CELL CHEMICAL BIOLOGY
IF7.2
2021-10-0118
OAAI
Cho, Hyelim; Shen, Qiong; Zhang, Lydia H.; Okumura, Mikiko; Kawakami, Akinori; Ambrose, Jessi; Sigoillot, Frederic; Miller, Howard R.; Gleim, Scott; Cobos-Correa, Amanda; Wang, Ying; Piechon, Philippe; Roma, Guglielmo; Eggimann, Fabian; Moore, Charles; Aspesi, Peter, Jr.; Mapa, Felipa A.; Burks, Heather; Ross, Nathan T.; Krastel, Philipp; Hild, Marc; Maimone, Thomas J.; Fisher, David E.; Nomura, Daniel K.; Tallarico, John A.; Canham, Stephen M.; Jenkins, Jeremy L.; Forrester, William C.
Systematic Chemogenetic Library Assembly
CELL CHEMICAL BIOLOGY
IF7.2
2020-09-0134
OAAI
Canham, Stephen M.; Wang, Yuan; Cornett, Allen; Auld, Douglas S.; Baeschlin, Daniel K.; Patoor, Maude; Skaanderup, Philip R.; Honda, Ayako; Llamas, Luis; Wendel, Greg; Mapa, Felipa A.; Aspesi, Peter, Jr.; Labbe-Giguere, Nancy; Gamber, Gabriel G.; Palacios, Daniel S.; Schuffenhauer, Ansgar; Deng, Zhan; Nigsch, Florian; Frederiksen, Mathias; Bushell, Simon M.; Rothman, Deborah; Jain, Rishi K.; Hemmerle, Horst; Briner, Karin; Porter, Jeffery A.; Tallarico, John A.; Jenkins, Jeremy L.
CPSF3-dependent pre-mRNA processing as a druggable node in AML and Ewing's sarcoma (vol 13, pg 465, 2019)
NATURE CHEMICAL BIOLOGY
IF13.7
2020-03-041
OAAI
Ross, Nathan T.; Lohmann, Felix; Carbonneau, Seth; Fazal, Aleem; Weihofen, Wilhelm A.; Gleim, Scott; Salcius, Michael; Sigoillot, Frederic; Henault, Martin; Carl, Sarah H.; Rodriguez-Molina, Juan B.; Miller, Howard R.; Brittain, Scott M.; Murphy, Jason; Zambrowski, Mark; Boynton, Geoffrey; Wang, Yuan; Chen, Aye; Molind, Gregory J.; Wilbertz, Johannes H.; Artus-Revel, Caroline G.; Jia, Min; Akinjiyan, Favour A.; Turner, Jonathan; Knehr, Judith; Carbone, Walter; Schuierer, Sven; Reece-Hoyes, John S.; Xie, Kevin; Saran, Chitra; Williams, Eric T.; Roma, Guglielmo; Spencer, Matt; Jenkins, Jeremy; George, Elizabeth L.; Thomas, Jason R.; Michaud, Gregory; Schirle, Markus; Tallarico, John; Passmore, Lori A.; Chao, Jeffrey A.; Beckwith, Rohan E. J.
CPSF3-dependent pre-mRNA processing as a druggable node in AML and Ewing's sarcoma
NATURE CHEMICAL BIOLOGY
IF13.7
2019-12-0970
OAAI
Ross, Nathan T.; Lohmann, Felix; Carbonneau, Seth; Fazal, Aleem; Weihofen, Wilhelm A.; Gleim, Scott; Salcius, Michael; Sigoillot, Frederic; Henault, Martin; Carl, Sarah H.; Rodriguez-Molina, Juan B.; Miller, Howard R.; Brittain, Scott M.; Murphy, Jason; Zambrowski, Mark; Boynton, Geoffrey; Wang, Yuan; Chen, Aye; Molind, Gregory J.; Wilbertz, Johannes H.; Artus-Revel, Caroline G.; Jia, Min; Akinjiyan, Favour A.; Turner, Jonathan; Knehr, Judith; Carbone, Walter; Schuierer, Sven; Reece-Hoyes, John S.; Xie, Kevin; Saran, Chitra; Williams, Eric T.; Roma, Guglielmo; Spencer, Matt; Jenkins, Jeremy; George, Elizabeth L.; Thomas, Jason R.; Michaud, Gregory; Schirle, Markus; Tallarico, John; Passmore, Lori A.; Chao, Jeffrey A.; Beckwith, Rohan E. J.
Discovery of a ZIP7 inhibitor from a Notch pathway screen
NATURE CHEMICAL BIOLOGY
IF13.7
2019-01-1455
OA
Nolin, Erin; Gans, Sara; Llamas, Luis; Bandyopadhyay, Somnath; Brittain, Scott M.; Bernasconi-Elias, Paula; Carter, Kyle P.; Loureiro, Joseph J.; Thomas, Jason R.; Schirle, Markus; Yang, Yi; Guo, Ning; Roma, Guglielmo; Schuierer, Sven; Beibel, Martin; Lindeman, Alicia; Sigoillot, Frederic; Chen, Amy; Xie, Kevin X.; Ho, Samuel; Reece-Hoyes, John; Weihofen, Wilhelm A.; Tyskiewicz, Kayla; Hoepfner, Dominic; McDonald, Richard, I; Guthrie, Nicolette; Dogra, Abhishek; Guo, Haibing; Shao, Jian; Ding, Jian; Canham, Stephen M.; Boynton, Geoff; George, Elizabeth L.; Karig, Zhao B.; Antcza, Christophe; Porter, Jeffery A.; Wallace, Owen; Tallarico, John A.; Palmer, Amy E.; Jenkins, Jeremy L.; Jain, Rishi K.; Bushell, Simon M.; Fryer, Christyj

研究方向

暂未获取到该数据
M
Meir Glick
H 指数:39论文数:151被引数:5,246
J
John W. Davies
H 指数:32论文数:54被引数:4,480
A
Andreas Bender
H 指数:70论文数:542被引数:1.8万
J
John A. Tallarico
H 指数:49论文数:126被引数:1.1万
F
Frederic Sigoillot
H 指数:25论文数:62被引数:2,778
M
Markus Schirle
H 指数:52论文数:143被引数:1.9万
F
Florian Nigsch
H 指数:29论文数:72被引数:4,495
M
Marc Hild
H 指数:27论文数:51被引数:1.0万
J
Josef Scheiber
H 指数:18论文数:49被引数:1,813
L
László Urbán
H 指数:73论文数:426被引数:5.3万