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徐进宜 封面图

徐进宜 (Jinyi Xu)

china pharmaceutical university

46H指数
347论文数
7.8K被引数
收录论文 168
发表时间
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Discovery of novel and potent 2-aminopyrazine-based HPK1 inhibitors enhancing T-cell immunity against cancer新型高效2-氨基吡嗪基HPK1抑制剂的发现，增强T细胞免疫以对抗癌症
errEuropean Journal of Medicinal Chemistry
IF5.9
err2026-04-15
err0
PREAI
errGuo, Zhichao; Duan, Yiping; Zhang, Baixue; Sun, Kai; Zheng, Tiandong; Chen, Lanlan; He, Chen; Feng, Jiajie; Lu, Yang; Xiong, Geting; Xu, Shengtao; Liu, Jie; Zhu, Zheying; Xu, Jinyi
err分享
err收藏
Discovery of Novel Snail Inhibitors Derived from Omeprazole for Antiatherosclerotic Therapy: A Structure-Based Approach基于结构的奥美拉唑衍生物新型 Slug 抑制剂的发现及其抗动脉粥样硬化治疗应用
errJournal of Medicinal Chemistry
IF6.8
err2026-02-10
err0
PREAI
errZhaolan Zeng; Yang Lu; Mengsha Fang; Xiaopeng Guo; Wenyi Zhong; Geting Xiong; Yu Wang; Fengze Sun; Jinyi Xu; Zhaoqiu Wu; Rong Fu; Jie Liu
err分享
err收藏
Discovery of SY-589; a Highly Potent and Orally Bioavailable Polθ Helicase Inhibitor for the Treatment of HR-Deficient Tumors
errJournal of Medicinal Chemistry
IF6.8
err2026-01-23
err0
PREAI
errChongxun Ge; Dazhi Feng; Song Shi; Xuzhen Tang; Yaqi Cui; Song Liu; Yunyue Wang; Shuangtian Tang; Xinnan Li; Xianqiang Sun; Daopeng Yuan; Jinyi Xu; Hu He; Hong Yao
err分享
err收藏
Discovery of 8-Quinolinesulfonamide Phenylimidazole-based PKM2 Agonists for the Prevention and Delay of Aortic Dissection发现8-喹啉磺酰胺基苯并咪唑类PKM2激动剂，用于预防和延缓主动脉夹层
errEuropean Journal of Medicinal Chemistry
IF5.9
err2025-12-13
err0
PREAI
errJunda Li; Yanyan Yang; Lei Cheng; Xu Xu; Ke Zhong; Tao Wang; Kailin Chen; Chi Zhang; Chen He; Jinyi Xu; Shengtao Xu; Shanshan Luo
err分享
err收藏
Discovery of Novel Bifunctional Agents as Potent TRK Inhibitors and Degraders against xDFG Mutation Resistance
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2025-12-01
err0
PREAI
errSong, Jian; Zhu, Jingjie; Zhu, Wenjian; Feng, Jinwei; Fan, Jiarong; Mei, Yi; Shi, Qiren; Yang, Yuzhuo; Feng, Zhijie; Wang, Peng; Wang, Tianduanyi; Xu, Shengtao; Xu, Jinyi; Zhu, Huajian
err分享
err收藏
Construction of Small-Molecule Deubiquitinase-Targeting Chimeras to Reactivate and Stabilize Mutant p53 Y220C in Vitro and in Vivo靶向去泛素酶的小分子嵌合体的构建，以在体内外重新激活和稳定突变体p53 Y220C
errANGEWANDTE CHEMIE-INTERNATIONAL EDITION
IF16.9
err2025-11-01
err0
PREAI
errHe, Chen; Li, Junda; Cui, Chenxi; Xie, Jia; Feng, Jiajie; Zhang, Baixue; Huang, Xingting; Ma, Ruoping; Zheng, Lufeng; Xu, Jinyi; Yao, Hong; Xu, Shengtao
err分享
err收藏
Rational design of the linkers in targeting chimeras靶向嵌合体中连接子的理性设计
errChem. Sci.
IF7.4
err2025-09-22
err0
errOAAI
errYiping Duan; Michelle Y. Cai; Jinyi Xu; Quanyin Hu
err分享
err收藏
Modulating G6PD/PGD to overcome FSP1/DHODH-mediated ferroptosis defence: A novel oridonin derivative suppresses liver cancer通过调节G6PD/PGD以克服FSP1/DHODH介导的铁死亡防御：一种新型奥多尼丁衍生物抑制肝癌
errBritish Journal of Pharmacology
IF7.7
err2025-08-27
err0
PREAI
errChenhui Ma; Li Han; Hong Yao; Wenxuan Zhao; Feihong Chen; Xiuyuan Wu; Guoqi Li; Ruimin Huang; Cheng Heng Pang; Zheying Zhu; Jinyi Xu; Guoyu Pan
err分享
err收藏
Development of Adamantane-based hydrophobic tags targeting anaplastic lymphoma kinase with enhanced antitumor activities基于金刚烷的疏水标签的研制：靶向间变性淋巴瘤激酶并增强抗肿瘤活性
errBioorganic Chemistry
IF4.7
err2025-08-14
err0
PREAI
errJingjie Zhu; Fangyi Zhan; Jia Xie; Tonghao Fang; Yuan Sun; Feiyan Zhan; Tian Gao; Jingyu Liu; Jiajie Feng; Pijun Zhou; Huajian Zhu; Hong Yao; Zheying Zhu; Shengtao Xu; Jinyi Xu; Shaowen Xie
err分享
err收藏
Se-lectively Triggered: ROS-Activated Michael Acceptor Prodrug Strategy to Enhance Tumor Targeting Efficacy选择性触发：ROS激活的迈克尔受体前药策略以增强肿瘤靶向效能
errChem. Sci.
IF7.4
err2025-07-25
err0
errOAAI
errDazhi Feng; Xinnan Li; Junkai Liu; Xiao Shao; Lihua Liu; Yuning Shi; Yunyue Wang; Minghui Yu; Shuangtian Tang; li Deng; Yongjie Zhang; Shaowen Xie; Jinyi Xu; Shengtao Xu; Hong Yao
err分享
err收藏
Overcoming E3 Ligase-Mediated Resistance: Development of Novel Hydrophobic Tagging-Based Degraders Targeting ALK Protein克服E3连接酶介导的耐药性：基于新型疏水标签的ALK蛋白降解剂的开发
errJournal of Medicinal Chemistry
IF6.8
err2025-07-24
err0
PREAI
errShaowen Xie; Jingjie Zhu; Fangyi Zhan; Dazhi Feng; Chen He; Lihua Liu; Jia Xie; Jingyu Liu; Ming Zhong; Xingting Zhang; Jinyi Xu; Hong Yao; Shengtao Xu
err分享
err收藏
The latest advances with natural products in drug discovery and opportunities for the future: a 2025 update天然产物在药物发现中的最新进展与未来机遇：2025年更新
errExpert Opinion on Drug Discovery
IF4.9
err2025-06-05
err0
PREAI
errShaowen Xie; Fangyi Zhan; Jingjie Zhu; Shengtao Xu; Jinyi Xu
err分享
err收藏
Effect of egg white on the structure and properties of starch in wheat noodles
errJOURNAL OF CEREAL SCIENCE
IF3.7
err2025-05-01
err0
PREAI
errXu, Jinyi; Sang, Shangyuan; Zhang, Jinye; Xing, Jiali; He, Rong; Xu, Fuxing; Fang, Guanghui; Ouyang, Dan; Wan, Ying; Luo, Xiaohu
err分享
err收藏
Synergistic Amylase and Debranching Enzyme Catalysis to Improve the Stability of Oat Milk协同淀粉酶和脱支酶催化以提高燕麦奶的稳定性
errFOODS
IF5.1
err2025-04-05
err0
errOAAI
errZhan, Xinyan; Zhang, Jinye; Xing, Jiali; Xu, Jinyi; Ouyang, Dan; Wang, Li; Wan, Ying; Luo, Xiaohu
err分享
err收藏
Novel agents derived from natural product /3-elemene: A second round of design and synthesis to enhance antitumor properties
errBIOORGANIC & MEDICINAL CHEMISTRY
IF3
err2025-04-01
err0
PREAI
errLiu, Zhouyan; Li, Tong; Gu, Chenglei; Chen, Cheng; Tang, Ziwei; Feng, Yanyan; Zhou, Chen; Xu, Jinyi; Chen, Jichao
err分享
err收藏
Assessing the Therapeutic Value of Primary Tumor Resection in Colorectal Cancer Lung Metastases: A Dynamic Visualization Clinical Tool Constructed Based on the SEER Database评估结直肠癌肺转移原发肿瘤切除的治疗价值: 基于SEER数据库构建的动态可视化临床工具
errJOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
IF3.4
err2025-02-25
err0
PREAI
errXu, Jinyi; Niu, Xiaoqiang
err分享
err收藏
In Vivo Self-Assembly of PROTACs by Bioorthogonal Chemistry for Precision Cancer Therapy体内通过生物正交化学实现PROTACs的自组装，用于精准癌症治疗
errANGEWANDTE CHEMIE-INTERNATIONAL EDITION
IF16.9
err2025-01-07
err0
PREAI
errXie, Shaowen; Zhu, Jingjie; Peng, Yihan; Zhan, Fangyi; Zhan, Feiyan; He, Chen; Feng, Dazhi; Xie, Jia; Liu, Jingyu; Zhu, Huajian; Yao, Hong; Xu, Jinyi; Su, Zhigui; Xu, Shengtao
err分享
err收藏
Cardiac deceleration capacity and acceleration capacity have diagnostic value in patients with vasovagal syncope regardless of age心脏减速能力和加速能力在血管迷走性晕厥患者中具有诊断价值，且与年龄无关。
errFRONTIERS IN CARDIOVASCULAR MEDICINE
IF2.9
err2024-12-18
err0
errOAAI
errWang, Jijing; Xu, Jinyi; Qiu, Yanyan; Yang, Ruike; Wang, Wentao; Gao, Chuanyu
err分享
err收藏
Theoretical study on the mechanism of slope sliding resistance and sliding force on multi-field coupling instability
errAIN SHAMS ENGINEERING JOURNAL
IF5.9
err2024-12-01
err0
errOAAI
errLiang, Zhenxing; Xu, Jinyi; Cao, Haiqing; Zeng, Yinyong; Wu, Tingyao
err分享
err收藏
Insights into direct KRAS inhibition strategies for cancer treatment
errFUTURE MEDICINAL CHEMISTRY
IF3.4
err2024-11-21
err0
PREAI
errLi, Tong; Gu, Chenglei; Zhou, Chen; Mao, Chunqin; Yang, Kan; Xu, Jinyi; Lu, Tulin; Chen, Jichao
err分享
err收藏

研究方向

Yao, H.Qiu, Y.Y.Zhou, M.Z.Li, D.H.*Wu, L.*Yang, D.H.Chen, Z.S.Polycyclic Heterocyclic DerivativesTriple-Negative Breast CancerYin Y.Liu, J.Qin, S.Li, X. N.Allen, SBai R. R.Gong, Q.Zhang, H.Y.*Zhu, Z.Y.*Sun, Y.Liu, Y.L.Li, X.N.Zhong, W.Y.Zhan, F.Y.Zhu, J.J.Xu, J.Y.*Xie, S.W.Ma, X.Q.Liu, J.K.Wu H.Y.Lin A.J.Yao, H.Q.Li, D.H.Xu, S.T.*triple-negative breast canceroridonin analogueXu, F.J.Shuai, W.Sun, H.H.Ma, C.Xu, S.T.* Yao, H.Q.Zhu, Z.Y.抗肿瘤药物微管聚合抑制剂Luo, S.S.Liu, Y.P.硫化氢缓释供体心脏保护剂Zhang, Y.K.Wang, G.Y.Hu, Mei.Wu, X.M.* Xie, W.J.Cai, H.Miao, X.M.Wu, F.* Yang, D.H.Xie, W.J.冬凌草甲素抗癌作用荧光类似物亚细胞定位Shao X.Xue S.T.Du P.Wu, H.Y.Chen, Z. S.Yang, D. H.Yao, H.*He, C.Jia, Y.L.分子胶通过诱导蛋白质聚集调节蛋白质功能作为疾病治疗的小分子策略
合作学者
合作期刊
M
Michael Karin
H 指数: 254 · 论文数: 904
A
Andrea Natale
H 指数: 136 · 论文数: 2.1K
T
Thomas J. Kipps
H 指数: 120 · 论文数: 1.0K
陈涛 封面图
陈涛 (Tao Chen)
H 指数: 107 · 论文数: 1.4K
刘建国 封面图
刘建国 (Jianguo Liu)
H 指数: 104 · 论文数: 841
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