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Leggy A. Arnold

University of Wisconsin-Milwaukee

36H指数
188论文数
4.7K被引数
收录论文 66
发表时间
Development of Novel Pegylated Imidazobenzodiazepines Targeting α5 GABAA Receptors for Anxiety: A Comparative Prodrug and Metabolite Study新型聚乙二醇化咪唑苯二氮䓬类靶向α5 GABAA受体抗焦虑药物的研发:一种比较前药和代谢物的研究
err2026-09-02
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PREAI
errMubaraq A. Toriola; Ethan T. Kowalczyk; Kayode M. Medubi; Michelle J. Meyer; Maya R. T. Fernando; Petra Scholze; Nethyanji Premananda; Shaun G. Harrington; Braden R. Barkley; Daniel A. Webb; Leggy A. Arnold
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Assessing Age and Cold Ischemia Effects on Liver Tissue Viscoelastic Properties: Implications for Graft Quality Assessment with MRE during Machine Perfusion评估年龄和冷缺血对肝组织黏弹性特性的影响:对机械灌注期间MRE进行移植物质量评估的启示
err2025-12-01
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errOAAI
errLisa-Marie Skrip; Leonard Boerger; Kilian A. Walter; Alexander Arnold; Lene A. Böhne; Eriselda Keshi; Anna S. Pietsch; Nathanael Raschzok; Timo A. Auer; Uli Fehrenbach; Felix Krenzien; Johann Pratschke; Igor M. Sauer; Jing Guo; Jürgen Braun; Heiko Tzschätzsch; Ingolf Sack; Karl H. Hillebrandt; Simon Moosburner
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Development of novel pegylated imidazobenzodiazepines as inhaled asthma drug candidates
err2025-10-01
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PREAI
errKowalczyk, Ethan T.; Medubi, Kayode M.; Meyer, Michelle J.; Toriola, Mubaraq A.; Haasch, Tyler J.; Vesperman, Makena R.; Webb, Daniel A.; Stafford, Douglas C.; Yocum, Gene T.; Emala, Charles W.; Arnold, Leggy A.
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Inactivation of ATG13 stimulates chronic demyelinating pathologies in muscle-serving nerves and spinal cord
err2025-01-07
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errDrosen, Molly E.; Bulbule, Sarojini; Gottschalk, Gunnar; Peterson, Daniel; Allen, Linda Adrienne; Arnold, Leggy A.; Roy, Avik
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Exploring structural features of sleep-enhancing peptides derived from casein hydrolysates by chemometrics and random forest methodology
err2024-12-01
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PREAI
errQian, Jingjing; Yu, Fengjie; Arnold, Leggy A.; Saha, Arjun; Zheng, Lin; Zhao, Mouming
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JRM-28, a Novel HDAC2 Inhibitor, Upregulates Plasticity-Associated Proteins in Hippocampal Neurons and Enhances Morphological Plasticity via Activation of CREB: Implications for Alzheimer's Disease
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IF5.2
err2024-11-27
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errRahman, A. F. M. Towheedur; Bulbule, Sarojini; Belayet, Jawad Bin; Benko, Anna; Gottschalk, Carl Gunnar; Frick, David N.; Arnold, Leggy A.; Hossain, M. Mahmun; Roy, Avik
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Mitochondrial Fission Protein 1 (Fis1) Regulates Endothelial Function in Resistance Arterioles in Health and Cardiometabolic Disease线粒体分裂蛋白1 (Fis1) 调节阻力动脉中的内皮功能,并涉及健康和心血管代谢疾病状态。
err2024-11-12
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PREAI
errWang, Jingli; Nolden, Kelsey; Egner, John; Kakarla, Mamatha; Harwig, Megan; Roberts, Michelle; Arnold, Leggy; Hofeld, Benjamin; Ying, Rong; Wilcox, Taylor; Hill, R.; Widlansky, Michael
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Clinical prognosticators and targets in the immune microenvironment of intrahepatic cholangiocarcinoma
err2024-10-01
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errLozzi, Isis; Arnold, Alexander; Barone, Matthias; Johnson, Juliette Claire; Sinn, Bruno, V; Eschrich, Johannes; Gebert, Pimrapat; Wang, Ruonan; Hu, Mengwen; Feldbruegge, Linda; Schirmeier, Anja; Reutzel-Selke, Anja; Malinka, Thomas; Krenzien, Felix; Schoening, Wenzel; Modest, Dominik P.; Pratschke, Johann; Sauer, Igor M.; Felsenstein, Matthaeus
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Extracellular NAD+ response to post-hepatectomy liver failure: bridging preclinical and clinical findings
err2024-08-14
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errKamali, Can; Brunnbauer, Philipp; Kamali, Kaan; Saqr, Al-Hussein Ahmed; Arnold, Alexander; Harman Kamali, Gulcin; Babigian, Julia; Keshi, Eriselda; Mohr, Raphael; Felsenstein, Matthaeus; Moosburner, Simon; Hillebrandt, Karl-Herbert; Bartels, Jasmin; Sauer, Igor Maximilian; Tacke, Frank; Schmelzle, Moritz; Pratschke, Johann; Krenzien, Felix
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Novel Oral Treatment for Atopic Dermatitis: Allosteric Modulation of GABAA Receptor Signaling
err2024-05-01
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PREAI
errMeyer, Michelle; Webb, Daniel; Lee, Majia; Kowalczyk, Ethan; Stafford, Douglas; Arnold, Leggy
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New Imidazodiazepine Analogue, 5-(8-Bromo-6-(pyridin-2-yl)-4H-benzo[f]imidazo[1,5-a][1,4]diazepin-3-yl)oxazole, Provides a Simplified Synthetic Scheme, High Oral Plasma and Brain Exposures, and Produces Antiseizure Efficacy in Mice, and Antiepileptogenic Activity in Neural Networks in Brain Slices from a Patient with Mesial Temporal Lobe Epilepsy
err2024-01-04
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PREAI
errSharmin, Dishary; Divovic, Branka; Ping, Xingjie; Cerne, Rok; Smith, Jodi L.; Rezvanian, Sepideh; Mondal, Prithu; Meyer, Michelle Jean; Kiley, Molly E.; Arnold, Leggy A.; Mian, Md Yeunus; Pandey, Kamal P.; Jin, Xiaoming; Mitrovic, Jelena R.; Djorovic, Djordje; Lippa, Arnold; Cook, James M.; Golani, Lalit K.; Scholze, Petra; Savic, Miroslav M.; Witkin, Jeffrey M.
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Design, Synthesis, and Biological Evaluation of Novel Spiro Imidazobenzodiazepines to Identify Improved Inhaled Bronchodilators
err2023-07-07
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errWebb, Daniel A.; Meyer, Michelle J.; Medubi, Kayode M.; Tylek, Anika S.; Yocum, Gene T.; Roni, M. S. Rashid; Zahn, Nicolas M.; Swartwout, Sarah A.; Masoud, Ahmad K.; Emala, Charles W.; Stafford, Douglas C.; Arnold, Leggy A.
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Structural Analogs of the GABAkine KRM-II-81 Are Orally Bioavailable Anticonvulsants without Sedation
err2023-04-01
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errPandey, Kamal P.; Divovic, Branka; Rashid, Farjana; Golani, Lalit K.; Cerne, Rok; Zahn, Nicolas M.; Meyer, Michelle Jean; Arnold, Leggy A.; Sharmin, Dishary; Mian, Md Yeunus; Smith, Jodi L.; Ping, Xingjie; Jin, Xiaoming; Lippa, Arnold; Tiruveedhula, V. V. N. Phani Babu; Cook, James M.; Savic, Miroslav M.; Witkin, Jeffrey M.
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Comparative anticonvulsant activity of the GABAkine KRM-II-81 and a deuterated analogGABAkine KRM-II-81和氘代类似物的抗惊厥活性比较
err2023-02-07
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errPing, Xingjie; Meyer, Michelle J.; Zahn, Nicolas M.; Golani, Lalit K.; Sharmin, Dishary; Pandey, Kamal P.; Revanian, Sepideh; Mondal, Prithu; Jin, Xiaoming; Arnold, Leggy A.; Cerne, Rok; Cook, James M.; Divovic, Branka; Savic, Miroslav M.; Lippa, Arnold; Smith, Jodi L.; Witkin, Jeffrey M.
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Imidazobenzodiazepine PI320 Relaxes Mouse Peripheral Airways by Inhibiting Calcium Mobilization
err2022-10-01
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errPerez-Zoghbi, Jose F.; Sajorda, Dannah Rae; Webb, Daniel A.; Arnold, Leggy A.; Emala, Charles W.; Yocum, Gene T.
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Identification of a Vitamin-D Receptor Antagonist, MeTC7, whichInhibits the Growth of Xenograft and Transgenic Tumors In Vivo
err2022-04-11
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errOAAI
errKhazan, Negar; Kim, Kyu Kwang; Hansen, Jeanne N.; Singh, Niloy A.; Moore, Taylor; Snyder, Cameron W. A.; Pandita, Ravina; Strawderman, Myla; Fujihara, Michiko; Takamura, Yuta; Jian, Ye; Battaglia, Nicholas; Yano, Naohiro; Teramoto, Yuki; Arnold, Leggy A.; Hopson, Russell; Kishor, Keshav; Nayak, Sneha; Ojha, Debasmita; Sharon, Ashoke; Ashton, John M.; Wang, Jian; Milano, Michael T.; Miyamoto, Hiroshi; Linehan, David C.; Gerber, Scott A.; Kawar, Nada; Singh, Ajay P.; Tabdanov, Erdem D.; Dokholyan, Nikolay, V; Kakuta, Hiroki; Jurutka, Peter W.; Schor, Nina F.; Rowswell-Turner, Rachael B.; Singh, Rakesh K.; Moore, Richard G.
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Comparative pharmacodynamic and pharmacokinetic study of MIDD0301 and its (S) enantiomer
err2022-03-04
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errOAAI
errRoni, M. S. Rashid; Zahn, Nicolas M.; Yocum, Gene T.; Webb, Daniel A.; Mian, Md Yeunus; Meyer, Michelle J.; Tylek, Anika S.; Cook, James M.; Emala, Charles W.; Stafford, Douglas C.; Arnold, Leggy A.
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Development of a Novel, Small-Molecule Brain-Penetrant Histone Deacetylase Inhibitor That Enhances Spatial Memory Formation in Mice
err2022-02-08
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errOAAI
errBelayet, Jawad B.; Beamish, Sarah; Rahaman, Mizzanoor; Alanani, Samer; Virdi, Rajdeep S.; Frick, David N.; Rahman, A. F. M. Towheedur; Ulicki, Joseph S.; Biswas, Sreya; Arnold, Leggy A.; Roni, M. S. Rashid; Cheng, Eric Y.; Steeber, Douglas A.; Frick, Karyn M.; Hossain, M. Mahmun
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A Structure-Activity Relationship Comparison of Imidazodiazepines Binding at Kappa, Mu, and Delta Opioid Receptors and the GABAA Receptor在Kappa,Mu和Delta阿片受体和GABAA受体上结合的咪唑并二氮的构效关系比较
err2020-08-25
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errLi, Guanguan; Nieman, Amanda N.; Mian, Md Yeunus; Zahn, Nicolas M.; Mikulsky, Brandon N.; Poe, Michael M.; Methuku, Kashi R.; Liu, Yongfeng; Cook, James M.; Stafford, Douglas C.; Arnold, Leggy A.
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