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L

Lhassane Ismaïli

universite de franche-comte and inserm
H指数:26
被引数:1,992

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Polyfunctionalized N-Arylsulfonyl Indoles: Identification of (E)-N-Hydroxy-3-{3-[(5-(3-(piperidin-1-yl)propoxy]-1H-indol-1-yl)sulfonyl]phenyl}acrylamide (MTP150) for the Epigenetic-based Therapy of Parkinson’s Disease

多官能化N-芳基磺酰基吲哚：用于表观遗传学基础治疗帕金森病的(E)-N-羟基-3-{3-[(5-(3-(哌啶-1-基)丙氧基)-1H-吲哚-1-基)磺酰基]苯基}丙烯酰胺（MTP150）的鉴定

International Journal of Molecular Sciences
IF4.9
2026-03-310
OAAI
Mireia Toledano-Pinedo; Alicia Porro-Pérez; Linda Schäker-Hübner; Daniel Diez-Iriepa; Isabel Iriepa; Agata Siwek; Małgorzata Wolak; Grzegorz Satała; Andrzej J. Bojarski; Agata Doroz-Płonka; Jadwiga Handzlik; Justyna Godyń; Patrick Dallemagne; Christophe Rochais; Audrey Davis; Marc Since; Belén Pérez; Aina Bellver-Sanchis; Alba Irisarri; Mercè Pallàs; Cristina Solana-Manrique; Francisco López-Muñoz; Lhassane Ismaili; Christian Griñán-Ferré; Nuria Paricio; Finn K. Hansen; Anna Więckowska; José Marco-Contelles
Multicomponent Synthesis of Multi-Target Quinazolines Modulating Cholinesterase, Oxidative Stress, and Amyloid Aggregation Activities for the Therapy of Alzheimer’s Disease

多组分合成靶向调节胆碱酯酶、氧化应激和淀粉样蛋白聚集活性的多靶点喹唑啉类化合物，用于阿尔茨海默症的治疗

Molecules 2025, Vol. 30, Page 3930
IF4.6
2025-09-300
OAAI
Saida Chakhari; José Marco-Contelles; Isabel Iriepa; Maria do Carmo Carreiras; Fakher Chabchoub; Lhassane Ismaili; Bernard Refouvelet
Discovery of New Highly Potent Histamine H3 Receptor Antagonists, Calcium Channel Blockers, and Acetylcholinesterase Inhibitors
ACS CHEMICAL NEUROSCIENCE
IF3.9
2024-08-290
PRE
Malek, Rim; Salat, Kinga; Totoson, Perle; Karcz, Tadeusz; Refouvelet, Bernard; Skrzypczak-Wiercioch, Anna; Maj, Maciej; Simakov, Alexey; Martin, Helene; Siwek, Agata; Szalaj, Natalia; Godyn, Justyna; Panek, Dawid; Wieckowska, Anna; Jozwiak, Krzysztof; Demougeot, Celine; Kiec-Kononowicz, Katarzyna; Chabchoub, Fakher; Iriepa, Isabel; Marco-Contelles, Jose; Ismaili, Lhassane
(±)-BIGI-3h: Pentatarget-Directed Ligand combining Cholinesterase, Monoamine Oxidase, and Glycogen Synthase Kinase 3β Inhibition with Calcium Channel Antagonism and Antiaggregating Properties for Alzheimer's Disease

(±)-BIGI-3h: 结合胆碱酯酶，单胺氧化酶和糖原合酶激酶3β 抑制作用的Pentatarget定向配体，具有钙通道拮抗作用和抗聚集特性，可用于阿尔茨海默氏病

ACS CHEMICAL NEUROSCIENCE
IF3.9
2021-04-0229
PREAI
Ismaili, Lhassane; Monnin, Julie; Etievant, Adeline; Arribas, Raquel L.; Viejo, Lucia; Refouvelet, Bernard; Soukup, Ondrej; Janockova, Jana; Hepnarova, Vendula; Korabecny, Jan; Kucera, Tomas; Jun, Daniel; Andrys, Rudolf; Musilek, Kamil; Baguet, Aurelie; Garcia-Frutos, Eva M.; De Simone, Angela; Andrisano, Vincenza; Bartolini, Manuela; de Los Rios, Cristobal; Marco-Contelles, Jose; Haffen, Emmanuel

研究方向

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J
José Marco‐Contelles
H 指数:56论文数:483被引数:1.2万
B
Bernard Refouvelet
H 指数:19论文数:73被引数:1,414
H
Hélène Martin
H 指数:30论文数:152被引数:2,666
I
Isabel Iriepa
H 指数:30论文数:139被引数:2,658
F
Fakher Chabchoub
H 指数:17论文数:85被引数:905
M
Mourad Chioua
H 指数:28论文数:121被引数:2,349
I
Ignacio Moraleda
H 指数:25论文数:41被引数:1,820
I
Irène Pachón-Angona
H 指数:8论文数:14被引数:343
K
Krzysztof Jóźwiak
H 指数:30论文数:180被引数:4,792
O
Ondřej Soukup
H 指数:41论文数:248被引数:5,442