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D

Drew Dudgeon

Regeneron
H指数:9
被引数:688

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CAR T cells based on fully human T cell receptor-mimetic antibodies exhibit potent antitumor activity in vivo

基于全人源T细胞受体模拟抗体的CAR T细胞在体内表现出强大的抗肿瘤活性。

SCIENCE TRANSLATIONAL MEDICINE
IF14.6
2025-03-260
PRE
Salzler, Robert; Dilillo, David J.; Saotome, Kei; Bray, Kevin; Mohrs, Katja; Hwang, Haun; Cygan, Kamil J.; Shah, Darshit; Rye-Weller, Anna; Kundu, Kunal; Badithe, Ashok; Zhang, Xiaoqin; Garnova, Elena; Torres, Marcela; Dhanik, Ankur; Babb, Robert; Delfino, Frank J.; Thwaites, Courtney; Dudgeon, Drew; Moore, Michael J.; Meagher, Thomas Craig; Decker, Corinne E.; Owczarek, Tomasz; Gleason, John A.; Yang, Xiaoran; Suh, David; Lee, Wen-Yi; Welsh, Richard; Macdonald, Douglas; Hansen, Johanna; Guo, Chunguang; Kirshner, Jessica R.; Thurston, Gavin; Huang, Tammy; Franklin, Matthew C.; Yancopoulos, George D.; Lin, John C.; Macdonald, Lynn E.; Murphy, Andrew J.; Chen, Gang; Olsen, Olav; Olson, William C.
A PD-1-targeted, receptor-masked IL-2 immunocytokine that engages IL-2Ra strengthens T cell-mediated anti-tumor therapies
CELL REPORTS MEDICINE
IF10.6
2024-10-010
OAAI
Wu, Jiaxi; Bloch, Nicolin; Chang, Aaron Y.; Bhavsar, Ramandeep; Wang, Qingqing; Crawford, Alison; DiLillo, David J.; Vazzana, Kristin; Mohrs, Katja; Dudgeon, Drew; Patel, Supriya; Ahmed, Hassan; Garg, Vidur; Amatulli, Michael; Antao, Olivia Q.; Yan, Yuetian; Wang, Shunhai; Ramos, Willy; Krueger, Pamela; Adler, Christina; Ni, Min; Wei, Yi; Guo, Chunguang; Macdonald, Lynn; Huang, Tammy; Ullman, Erica; Hermann, Aynur; Yancopoulos, George D.; Murphy, Andrew J.; Davis, Samuel; Olson, William C.; Lin, John C.; Smith, Eric; Zhang, Tong
REGN10597: A PD-1-targeted, receptor-masked wild type IL-2 with improved therapeutic window for cancer immunotherapy
MOLECULAR CANCER THERAPEUTICS
IF5.5
2023-12-010
PRE
Wu, Jiaxi; Bloch, Nicolin; Chang, Aaron; Bhaysar, Ramandeep; Wang, Qingqing; Patel, Supriya; Garg, Vidur; Shakil, Hassan; Amatulli, Michael; Dudgeon, Drew; Yan, Yuetian; Wang, Shunhai; Ramos, Willy; Krueger, Pamela; Vazzana, Kristin; Crawford, Alison; Idun, Jacqueline; Decker, Corinne; DiLillo, David; Chandwani, Samira; Huang, Tammy; Kirshner, Jessica; Guo, Chungguang; Macdonald, Lynn; Ullman, Erica; Hermann, Aynur; Olson, William; Davis, Samuel; Lin, John; Smith, Eric; Zhang, Tong
A PD-1-targeted, receptor-masked IL-2 immunocytokine with maintained potential to engage endogenous IL-2Ra drives selective stimulation of PD-1+ T cells and robust anti-tumor efficacy
CANCER RESEARCH
IF16.6
2023-04-041
PRE
Wu, Jiaxi; Bloch, Nicolin; Chang, Aaron; Bhavsar, Ramandeep; Patel, Supriya; Wang, Qingqing; Ahmed, Hassan Shakil; Garg, Vidur; Amatulli, Michael; Yan, Yuetian; Wang, Shunhai; Dudgeon, Drew; Ramos, Willy; Krueger, Pamela; Rafique, Ashique; Huang, Tammy; Ullman, Erica; Hermann, Aynur; Olson, William; Lin, John; Smith, Eric; Zhang, Tong
Generation of T-cell-redirecting bispecific antibodies with differentiated profiles of cytokine release and biodistribution by CD3 affinity tuning

通过CD3亲和力调节产生具有细胞因子释放和生物分布的分化特征的T细胞重定向双特异性抗体

SCIENTIFIC REPORTS
IF3.9
2021-07-1364
OAAI
Haber, Lauric; Olson, Kara; Kelly, Marcus P.; Crawford, Alison; DiLillo, David J.; Tavare, Richard; Ullman, Erica; Mao, Shu; Canova, Lauren; Sineshchekova, Olga; Finney, Jennifer; Pawashe, Arpita; Patel, Supriya; McKay, Ryan; Rizvi, Sahar; Damko, Ermelinda; Chiu, Danica; Vazzana, Kristin; Ram, Priyanka; Mohrs, Katja; D'Orvilliers, Amanda; Xiao, Jenny; Makonnen, Sosina; Hickey, Carlos; Arnold, Cody; Giurleo, Jason; Chen, Ya Ping; Thwaites, Courtney; Dudgeon, Drew; Bray, Kevin; Rafique, Ashique; Huang, Tammy; Delfino, Frank; Hermann, Aynur; Kirshner, Jessica R.; Retter, Marc W.; Babb, Robert; MacDonald, Douglas; Chen, Gang; Olson, William C.; Thurston, Gavin; Davis, Samuel; Lin, John C.; Smith, Eric
Tumor-targeted CD28 bispecific antibodies enhance the antitumor efficacy of PD-1 immunotherapy
SCIENCE TRANSLATIONAL MEDICINE
IF14.6
2020-06-2466
PREAI
Waite, Janelle C.; Wang, Bei; Haber, Lauric; Hermann, Aynur; Ullman, Erica; Ye, Xuan; Dudgeon, Drew; Slim, Rabih; Ajithdoss, Dharani K.; Godin, Stephen J.; Ramos, Ilyssa; Wu, Qi; Oswald, Erin; Poon, Patrick; Golubov, Jacquelynn; Grote, Devon; Stella, Jennifer; Pawashe, Arpita; Finney, Jennifer; Herlihy, Evan; Ahmed, Hassan; Kamat, Vishal; Dorvilliers, Amanda; Navarro, Elizabeth; Xiao, Jenny; Kim, Julie; Yang, Shao Ning; Warsaw, Jacqueline; Lett, Clarissa; Canova, Lauren; Schulenburg, Teresa; Foster, Randi; Krueger, Pamela; Garnova, Elena; Rafique, Ashique; Babb, Robert; Chen, Gang; Oristian, Nicole Stokes; Siao, Chia-Jen; Daly, Christopher; Gurer, Cagan; Martin, Joel; Macdonald, Lynn; MacDonald, Douglas; Poueymirou, William; Smith, Eric; Lowy, Israel; Thurston, Gavin; Olson, William; Lin, John C.; Sleeman, Matthew A.; Yancopoulos, George D.; Murphy, Andrew J.; Skokos, Dimitris
A class of costimulatory CD28-bispecific antibodies that enhance the antitumor activity of CD3-bispecific antibodies

一类增强CD3-bispecific抗体抗肿瘤活性的共刺激CD28-bispecific抗体

SCIENCE TRANSLATIONAL MEDICINE
IF14.6
2020-01-0894
OAAI
Skokos, Dimitris; Waite, Janelle C.; Haber, Lauric; Crawford, Alison; Hermann, Aynur; Ullman, Erica; Slim, Rabih; Godin, Stephen; Ajithdoss, Dharani; Ye, Xuan; Wang, Bei; Wu, Qi; Ramos, Ilyssa; Pawashe, Arpita; Canova, Lauren; Vazzana, Kristin; Ram, Priyanka; Herlihy, Evan; Ahmed, Hassan; Oswald, Erin; Golubov, Jacquelynn; Poon, Patrick; Havel, Lauren; Chiu, Danica; Lazo, Miguel; Provoncha, Kathleen; Yu, Kevin; Kim, Julie; Warsaw, Jacqueline J.; Oristian, Nicole Stokes; Siao, Chia-Jen; Dudgeon, Drew; Huang, Tammy; Potocky, Terra; Martin, Joel; MacDonald, Douglas; Oyejide, Adelekan; Rafique, Ashique; Poueymirou, William; Kirshner, Jessica R.; Smith, Eric; Olson, William; Lin, John; Thurston, Gavin; Sleeman, Matthew A.; Murphy, Andrew J.; Yancopoulos, George D.
Development of Clinical-Stage Human Monoclonal Antibodies That Treat Advanced Ebola Virus Disease in Nonhuman Primates

开发治疗非人类灵长类动物晚期埃博拉病毒疾病的临床阶段人类单克隆抗体

JOURNAL OF INFECTIOUS DISEASES
IF4.5
2018-05-31144
OAAI
Pascal, Kristen E.; Dudgeon, Drew; Trefry, John C.; Anantpadma, Manu; Sakurai, Yasuteru; Murin, Charles D.; Turner, Hannah L.; Fairhurst, Jeanette; Torres, Marcela; Rafique, Ashique; Yan, Ying; Badithe, Ashok; Yu, Kevin; Potocky, Terra; Bixler, Sandra L.; Chance, Taylor B.; Pratt, William D.; Rossi, Franco D.; Shamblin, Joshua D.; Wollen, Suzanne E.; Zelko, Justine M.; Carrion, Ricardo, Jr.; Worwa, Gabriella; Staples, Hilary M.; Burakov, Darya; Babb, Robert; Chen, Gang; Martin, Joel; Huang, Tammy T.; Erlandson, Karl; Willis, Melissa S.; Armstrong, Kimberly; Dreier, Thomas M.; Ward, Andrew B.; Davey, Robert A.; Pitt, Margaret L. M.; Lipsich, Leah; Mason, Peter; Olson, William; Stahl, Neil; Kyratsous, Christos A.

研究方向

暂未获取到该数据
W
William C. Olson
H 指数:58论文数:379被引数:1.4万
T
Tammy Huang
H 指数:22论文数:106被引数:6,667
A
Ashique Rafique
H 指数:33论文数:184被引数:7,214
J
John Lin
H 指数:33论文数:116被引数:4,052
E
Erica Ullman
H 指数:12论文数:84被引数:2,130
A
Aynur Hermann
H 指数:10论文数:71被引数:2,170
G
Gavin Thurston
H 指数:79论文数:489被引数:3.0万
P
Pamela Krueger
H 指数:9论文数:81被引数:870
G
George D. Yancopoulos
H 指数:203论文数:945被引数:16.4万
A
Alison Crawford
H 指数:23论文数:72被引数:5,051