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M

Matthew C. Franklin

regeneron pharmaceuticals
H指数:32
被引数:7,907

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Anticoagulation with mechanistically distinct FXI/FXIa antibodies amrecibart (REGN9933A2) and cenvacibart (REGN7508Cat)

使用作用机制不同的FXI/FXIa抗体amrecibart（REGN9933A2）和cenvacibart（REGN7508Cat）进行抗凝

Blood
IF23.1
2026-06-150
OAAI
Dan Chalothorn; Aaron Kithcart; Ethan Marin; Selin Somersan-Karakaya; KehDih Lai; Frederic Cauwberghs; Jon Ackroyd; Kusha Mohammadi; Anju Shrestha; George Ehrlich; Ashique Rafique; Ishita Chatterjee; Kei Saotome; Matthew C. Franklin; Andrew J. Murphy; William Olson; Benjamin A. Olenchock; Gary A. Herman; David E. Gutstein; Andres Sirulnik
CAR T cells based on fully human T cell receptor-mimetic antibodies exhibit potent antitumor activity in vivo

基于全人源T细胞受体模拟抗体的CAR T细胞在体内表现出强大的抗肿瘤活性。

SCIENCE TRANSLATIONAL MEDICINE
IF14.6
2025-03-260
PRE
Salzler, Robert; Dilillo, David J.; Saotome, Kei; Bray, Kevin; Mohrs, Katja; Hwang, Haun; Cygan, Kamil J.; Shah, Darshit; Rye-Weller, Anna; Kundu, Kunal; Badithe, Ashok; Zhang, Xiaoqin; Garnova, Elena; Torres, Marcela; Dhanik, Ankur; Babb, Robert; Delfino, Frank J.; Thwaites, Courtney; Dudgeon, Drew; Moore, Michael J.; Meagher, Thomas Craig; Decker, Corinne E.; Owczarek, Tomasz; Gleason, John A.; Yang, Xiaoran; Suh, David; Lee, Wen-Yi; Welsh, Richard; Macdonald, Douglas; Hansen, Johanna; Guo, Chunguang; Kirshner, Jessica R.; Thurston, Gavin; Huang, Tammy; Franklin, Matthew C.; Yancopoulos, George D.; Lin, John C.; Macdonald, Lynn E.; Murphy, Andrew J.; Chen, Gang; Olsen, Olav; Olson, William C.
VSIG4 interaction with heparan sulfates inhibits VSIG4-complement binding
GLYCOBIOLOGY
IF3.3
2023-06-212
OAAI
Ebstein, Sarah Y.; Rafique, Ashique; Zhou, Yi; Krasco, Amanda; Montalvo-Ortiz, Welby; Yu, Lola; Custodio, Luisaidy; Adam, Rene C.; Bloch, Nicolin; Lee, Ken; Adewale, Funmilola; Vergata, Dominic; Luz, Antonio; Coquery, Sebastien; Daniel, Benjamin; Ullman, Erica; Franklin, Matthew C.; Hermann, Aynur; Huang, Tammy; Olson, William; Davis, Samuel; Murphy, Andrew J.; Sleeman, Matthew A.; Wei, Joyce; Skokos, Dimitris
Blocking common ? chain cytokine signaling ameliorates T cell-mediated pathogenesis in disease models
SCIENCE TRANSLATIONAL MEDICINE
IF14.6
2023-01-117
PRE
Le Floc'h, Audrey; Nagashima, Kirsten; Birchard, Dylan; Scott, George; Ben, Li-Hong; Ajithdoss, Dharani; Gayvert, Kaitlyn; Hernandez, Annabel Romero; Herbin, Olivier; Tay, Amanda; Farrales, Pamela; Korgaonkar, Chandrashekhar K.; Pan, Hao; Shah, Sweta; Kamat, Vishal; Chatterjee, Ishita; Popke, Jon; Oyejide, Adelekan; Lim, Wei Keat; Kim, Jee H.; Huang, Tammy; Franklin, Matthew; Olson, William; Norton, Thomas; Perlee, Lorah; Yancopoulos, George D.; Murphy, Andrew J.; Sleeman, Matthew A.; Orengo, Jamie M.
A Biparatopic Antibody-Drug Conjugate to Treat MET-Expressing Cancers, Including Those that Are Unresponsive to MET Pathway Blockade
MOLECULAR CANCER THERAPEUTICS
IF5.5
2021-07-2629
OAAI
DaSilva, John O.; Yang, Katie; Surriga, Oliver; Nittoli, Thomas; Kunz, Arthur; Franklin, Matthew C.; Delfino, Frank J.; Mao, Shu; Zhao, Feng; Giurleo, Jason T.; Kelly, Marcus P.; Makonnen, Sosina; Hickey, Carlos; Krueger, Pamela; Foster, Randi; Chen, Zhaoyuan; Retter, Marc W.; Slim, Rabih; Young, Tara M.; Olson, William C.; Thurston, Gavin; Daly, Christopher
NMIHBA results from hypomorphic PRUNE1 variants that lack short-chain exopolyphosphatase activity
HUMAN MOLECULAR GENETICS
IF3.2
2020-10-2614
OAAI
Nistala, Harikiran; Dronzek, John; Gonzaga-Jauregui, Claudia; Chim, Shek Man; Rajamani, Saathyaki; Nuwayhid, Samer; Delgado, Dennis; Burke, Elizabeth; Karaca, Ender; Franklin, Matthew C.; Sarangapani, Prasad; Podgorski, Michael; Tang, Yajun; Dominguez, Melissa G.; Withers, Marjorie; Deckelbaum, Ron A.; Scheonherr, Christopher J.; Gahl, William A.; Malicdan, May C.; Zambrowicz, Brian; Gale, Nicholas W.; Gibbs, Richard A.; Chung, Wendy K.; Lupski, James R.; Economides, Aris N.
A Biparatopic Antibody That Modulates MET Trafficking Exhibits Enhanced Efficacy Compared with Parental Antibodies in MET-Driven Tumor Models
CLINICAL CANCER RESEARCH
IF10.2
2020-03-1326
OAAI
DaSilva, John O.; Yang, Katie; Bay, Andres E. Perez; Andreev, Julian; Ngoi, Peter; Pyles, Erica; Franklin, Matthew C.; Dudgeon, Drew; Rafique, Ashique; Dore, Anthony; Delfino, Frank J.; Potocky, Terra B.; Babb, Robert; Chen, Gang; MacDonald, Douglas; Olson, William C.; Thurston, Gavin; Daly, Christopher
Kappa-on-Heavy (KoH) bodies are a distinct class of fully-human antibody-like therapeutic agents with antigen-binding properties
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2019-12-264
OAAI
Macdonald, Lynn E.; Meagher, Karoline A.; Franklin, Matthew C.; Levenkova, Natasha; Hansen, Johanna; Badithe, Ashok T.; Zhong, Maggie; Krueger, Pamela; Rafique, Ashique; Tu, Naxin; Shevchuk, James; Wadhwa, Saurabh; Ehrlich, George; Bautista, Joannie; Grant, Craig; Esau, Lakeisha; Poueymirou, William T.; Auerbach, Wojtek; Morton, Lori; Babb, Robert; Chen, Gang; Huang, Tammy; MacDonald, Douglas; Graham, Kenneth; Gurer, Cagan; Voronina, Vera A.; McWhirter, John R.; Guo, Chunguang; Yancopoulos, George D.; Murphy, Andrew J.

研究方向

暂未获取到该数据
W
William C. Olson
H 指数:58论文数:379被引数:1.4万
A
Andrew Murphy
H 指数:81论文数:457被引数:3.1万
G
George D. Yancopoulos
H 指数:203论文数:945被引数:16.4万
A
Ashique Rafique
H 指数:33论文数:184被引数:7,214
T
Tammy Huang
H 指数:22论文数:106被引数:6,667
W
Wayne J. Fairbrother
H 指数:61论文数:263被引数:1.7万
L
Linda O. Elliott
H 指数:10论文数:21被引数:2,069
D
Domagoj Vucic
H 指数:58论文数:152被引数:2.3万
J
Jonah Cheung
H 指数:20论文数:60被引数:3,275
K
Kei Saotome
H 指数:18论文数:57被引数:3,756